LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Transmembrane protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HB83_LEIBR
TriTrypDb:
LbrM.20.3230 , LBRM2903_200046300 *
Length:
112

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 15
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 2, no: 5
NetGPI no yes: 0, no: 7
Cellular components
Term Name Level Count
GO:0016020 membrane 2 8
GO:0110165 cellular anatomical entity 1 8

Expansion

Sequence features

A4HB83
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HB83

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 105 109 PF00656 0.615
CLV_PCSK_SKI1_1 6 10 PF00082 0.556
DEG_Nend_Nbox_1 1 3 PF02207 0.447
DEG_SPOP_SBC_1 30 34 PF00917 0.609
DOC_PP1_RVXF_1 81 87 PF00149 0.702
DOC_USP7_UBL2_3 69 73 PF12436 0.563
DOC_WW_Pin1_4 93 98 PF00397 0.677
LIG_FHA_1 3 9 PF00498 0.420
LIG_GBD_Chelix_1 51 59 PF00786 0.414
LIG_PDZ_Class_3 107 112 PF00595 0.655
LIG_SH3_3 15 21 PF00018 0.417
LIG_UBA3_1 1 6 PF00899 0.436
LIG_UBA3_1 63 69 PF00899 0.247
MOD_CDK_SPK_2 93 98 PF00069 0.677
MOD_CDK_SPxK_1 93 99 PF00069 0.682
MOD_GlcNHglycan 75 78 PF01048 0.569
MOD_GSK3_1 29 36 PF00069 0.597
MOD_GSK3_1 73 80 PF00069 0.734
MOD_N-GLC_1 93 98 PF02516 0.477
MOD_NEK2_1 2 7 PF00069 0.427
MOD_NEK2_1 29 34 PF00069 0.471
MOD_NEK2_1 55 60 PF00069 0.490
MOD_NEK2_1 79 84 PF00069 0.623
MOD_Plk_1 30 36 PF00069 0.500
MOD_Plk_4 55 61 PF00069 0.525
MOD_ProDKin_1 93 99 PF00069 0.682
TRG_NLS_MonoExtC_3 97 103 PF00514 0.671
TRG_NLS_MonoExtN_4 97 102 PF00514 0.653

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8ILG5 Leishmania donovani 61% 100%
E9AEH7 Leishmania major 53% 100%
E9B5F3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 53% 69%
E9B5F4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 55% 100%
E9B5F5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 51% 69%
Q4Q2I0 Leishmania major 55% 69%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS