LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HB51_LEIBR
TriTrypDb:
LbrM.20.2910 , LBRM2903_200042600 *
Length:
153

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HB51
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HB51

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 139 141 PF00675 0.676
CLV_PCSK_FUR_1 137 141 PF00082 0.648
CLV_PCSK_KEX2_1 139 141 PF00082 0.676
CLV_PCSK_SKI1_1 146 150 PF00082 0.642
CLV_PCSK_SKI1_1 3 7 PF00082 0.565
CLV_PCSK_SKI1_1 66 70 PF00082 0.403
DEG_Nend_Nbox_1 1 3 PF02207 0.543
DOC_MAPK_gen_1 107 117 PF00069 0.511
DOC_MAPK_gen_1 88 95 PF00069 0.492
DOC_PP1_RVXF_1 111 118 PF00149 0.563
DOC_USP7_MATH_1 78 82 PF00917 0.396
DOC_WW_Pin1_4 132 137 PF00397 0.476
DOC_WW_Pin1_4 41 46 PF00397 0.496
LIG_14-3-3_CanoR_1 3 8 PF00244 0.488
LIG_14-3-3_CanoR_1 63 69 PF00244 0.517
LIG_DCNL_PONY_1 1 4 PF03556 0.447
LIG_FHA_1 136 142 PF00498 0.573
LIG_FHA_2 147 153 PF00498 0.549
LIG_SH2_STAP1 125 129 PF00017 0.546
MOD_CDK_SPK_2 132 137 PF00069 0.476
MOD_CDK_SPxxK_3 132 139 PF00069 0.478
MOD_CK1_1 135 141 PF00069 0.550
MOD_CK1_1 44 50 PF00069 0.436
MOD_CK1_1 81 87 PF00069 0.432
MOD_GlcNHglycan 14 17 PF01048 0.639
MOD_GlcNHglycan 28 31 PF01048 0.660
MOD_GSK3_1 3 10 PF00069 0.590
MOD_GSK3_1 52 59 PF00069 0.397
MOD_NEK2_1 117 122 PF00069 0.502
MOD_NEK2_1 7 12 PF00069 0.540
MOD_NEK2_1 95 100 PF00069 0.485
MOD_PIKK_1 147 153 PF00454 0.594
MOD_PIKK_1 32 38 PF00454 0.615
MOD_PKA_2 7 13 PF00069 0.524
MOD_Plk_1 56 62 PF00069 0.411
MOD_Plk_4 44 50 PF00069 0.396
MOD_Plk_4 95 101 PF00069 0.421
MOD_ProDKin_1 132 138 PF00069 0.481
MOD_ProDKin_1 41 47 PF00069 0.489
MOD_SUMO_rev_2 120 130 PF00179 0.542
TRG_ENDOCYTIC_2 53 56 PF00928 0.395
TRG_ENDOCYTIC_2 92 95 PF00928 0.476
TRG_ER_diArg_1 136 139 PF00400 0.644

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P447 Leptomonas seymouri 71% 100%
A0A1X0PAS5 Trypanosomatidae 62% 100%
A0A3S7X896 Leishmania donovani 80% 100%
A4IA99 Leishmania infantum 81% 100%
E9B5C1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 78% 100%
Q4Q2L2 Leishmania major 80% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS