LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HB19_LEIBR
TriTrypDb:
LbrM.20.2580 , LBRM2903_200037800 *
Length:
606

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HB19
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HB19

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 86 90 PF00656 0.647
CLV_NRD_NRD_1 144 146 PF00675 0.467
CLV_NRD_NRD_1 155 157 PF00675 0.463
CLV_PCSK_KEX2_1 144 146 PF00082 0.509
CLV_PCSK_KEX2_1 155 157 PF00082 0.550
CLV_PCSK_KEX2_1 31 33 PF00082 0.550
CLV_PCSK_PC1ET2_1 155 157 PF00082 0.497
CLV_PCSK_PC1ET2_1 31 33 PF00082 0.433
CLV_PCSK_SKI1_1 150 154 PF00082 0.399
CLV_PCSK_SKI1_1 319 323 PF00082 0.571
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P512 Leptomonas seymouri 37% 95%
A0A3Q8IIC9 Leishmania donovani 59% 96%
A4IA76 Leishmania infantum 59% 96%
E9B589 Leishmania mexicana (strain MHOM/GT/2001/U1103) 57% 96%
Q4Q2P4 Leishmania major 57% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS