LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HAZ3_LEIBR
TriTrypDb:
LbrM.20.2320 , LBRM2903_200033600 *
Length:
348

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HAZ3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HAZ3

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 23 27 PF00656 0.499
CLV_NRD_NRD_1 100 102 PF00675 0.608
CLV_NRD_NRD_1 58 60 PF00675 0.769
CLV_PCSK_KEX2_1 57 59 PF00082 0.855
CLV_PCSK_KEX2_1 69 71 PF00082 0.666
CLV_PCSK_KEX2_1 99 101 PF00082 0.568
CLV_PCSK_PC1ET2_1 69 71 PF00082 0.655
CLV_PCSK_SKI1_1 259 263 PF00082 0.566
CLV_PCSK_SKI1_1 78 82 PF00082 0.564
CLV_Separin_Metazoa 137 141 PF03568 0.571
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S5H7X2 Leishmania donovani 53% 100%
A4IA53 Leishmania infantum 53% 100%
E9B567 Leishmania mexicana (strain MHOM/GT/2001/U1103) 50% 100%
Q4Q2R8 Leishmania major 51% 98%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS