GAR domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HAX3_LEIBR

TriTrypDb:

LbrM.20.2120 , LBRM2903_200031900

Length:

834

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HAX3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HAX3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	224	228	PF00656	0.703
CLV_C14_Caspase3-7	370	374	PF00656	0.730
CLV_C14_Caspase3-7	493	497	PF00656	0.711
CLV_C14_Caspase3-7	616	620	PF00656	0.727
CLV_C14_Caspase3-7	90	94	PF00656	0.681
CLV_NRD_NRD_1	110	112	PF00675	0.639
CLV_NRD_NRD_1	166	168	PF00675	0.729
CLV_NRD_NRD_1	202	204	PF00675	0.689
CLV_NRD_NRD_1	380	382	PF00675	0.731
CLV_NRD_NRD_1	503	505	PF00675	0.712
CLV_NRD_NRD_1	626	628	PF00675	0.720
CLV_NRD_NRD_1	717	719	PF00675	0.721
CLV_NRD_NRD_1	739	741	PF00675	0.714
CLV_PCSK_KEX2_1	110	112	PF00082	0.639
CLV_PCSK_KEX2_1	166	168	PF00082	0.729
CLV_PCSK_KEX2_1	202	204	PF00082	0.689
CLV_PCSK_KEX2_1	379	381	PF00082	0.733
CLV_PCSK_KEX2_1	502	504	PF00082	0.716
CLV_PCSK_KEX2_1	625	627	PF00082	0.723
CLV_PCSK_KEX2_1	717	719	PF00082	0.721
CLV_PCSK_KEX2_1	739	741	PF00082	0.714
CLV_PCSK_SKI1_1	110	114	PF00082	0.640
CLV_PCSK_SKI1_1	372	376	PF00082	0.722
CLV_PCSK_SKI1_1	495	499	PF00082	0.699
CLV_PCSK_SKI1_1	52	56	PF00082	0.642
CLV_PCSK_SKI1_1	618	622	PF00082	0.713
CLV_PCSK_SKI1_1	702	706	PF00082	0.731
DEG_APCC_KENBOX_2	786	790	PF00400	0.772
DEG_Nend_Nbox_1	1	3	PF02207	0.691
DEG_SIAH_1	294	302	PF03145	0.815
DOC_CKS1_1	339	344	PF01111	0.861
DOC_MAPK_gen_1	110	120	PF00069	0.636
DOC_MAPK_gen_1	670	677	PF00069	0.804
DOC_MAPK_HePTP_8	667	679	PF00069	0.797
DOC_MAPK_MEF2A_6	670	679	PF00069	0.800
DOC_MAPK_MEF2A_6	79	86	PF00069	0.631
DOC_MAPK_MEF2A_6	96	104	PF00069	0.370
DOC_USP7_MATH_1	409	413	PF00917	0.719
DOC_USP7_MATH_1	462	466	PF00917	0.711
DOC_USP7_MATH_1	532	536	PF00917	0.708
DOC_USP7_MATH_1	585	589	PF00917	0.700
DOC_USP7_MATH_1	655	659	PF00917	0.738
DOC_USP7_MATH_1	678	682	PF00917	0.782
DOC_USP7_MATH_1	722	726	PF00917	0.682
DOC_WW_Pin1_4	291	296	PF00397	0.787
DOC_WW_Pin1_4	338	343	PF00397	0.860
LIG_14-3-3_CanoR_1	808	813	PF00244	0.720
LIG_BRCT_BRCA1_1	181	185	PF00533	0.689
LIG_BRCT_BRCA1_2	181	187	PF00533	0.688
LIG_CaM_IQ_9	809	824	PF13499	0.710
LIG_FHA_1	216	222	PF00498	0.700
LIG_FHA_1	334	340	PF00498	0.855
LIG_FHA_1	345	351	PF00498	0.680
LIG_FHA_1	4	10	PF00498	0.788
LIG_FHA_1	45	51	PF00498	0.647
LIG_FHA_1	465	471	PF00498	0.712
LIG_FHA_1	53	59	PF00498	0.488
LIG_FHA_1	588	594	PF00498	0.703
LIG_FHA_1	64	70	PF00498	0.338
LIG_FHA_1	714	720	PF00498	0.721
LIG_FHA_1	97	103	PF00498	0.672
LIG_FHA_2	173	179	PF00498	0.685
LIG_FHA_2	222	228	PF00498	0.702
LIG_FHA_2	269	275	PF00498	0.689
LIG_FHA_2	276	282	PF00498	0.632
LIG_FHA_2	316	322	PF00498	0.854
LIG_FHA_2	324	330	PF00498	0.711
LIG_FHA_2	406	412	PF00498	0.719
LIG_FHA_2	529	535	PF00498	0.708
LIG_FHA_2	63	69	PF00498	0.678
LIG_FHA_2	652	658	PF00498	0.730
LIG_FHA_2	759	765	PF00498	0.681
LIG_FHA_2	88	94	PF00498	0.665
LIG_GBD_Chelix_1	794	802	PF00786	0.719
LIG_LIR_Gen_1	274	283	PF02991	0.718
LIG_LIR_Gen_1	38	45	PF02991	0.637
LIG_LIR_Gen_1	764	773	PF02991	0.678
LIG_LIR_Gen_1	788	798	PF02991	0.747
LIG_LIR_Nem_3	108	112	PF02991	0.638
LIG_LIR_Nem_3	142	148	PF02991	0.838
LIG_LIR_Nem_3	274	279	PF02991	0.728
LIG_LIR_Nem_3	38	42	PF02991	0.628
LIG_LIR_Nem_3	770	775	PF02991	0.686
LIG_LIR_Nem_3	788	794	PF02991	0.445
LIG_PCNA_PIPBox_1	680	689	PF02747	0.783
LIG_PDZ_Class_1	829	834	PF00595	0.766
LIG_Rb_LxCxE_1	727	747	PF01857	0.705
LIG_RPA_C_Fungi	384	396	PF08784	0.711
LIG_RPA_C_Fungi	507	519	PF08784	0.701
LIG_RPA_C_Fungi	630	642	PF08784	0.706
LIG_SH2_CRK	276	280	PF00017	0.719
LIG_SH2_SRC	772	775	PF00017	0.683
LIG_SH2_STAP1	276	280	PF00017	0.719
LIG_SH2_STAP1	283	287	PF00017	0.593
LIG_SH2_STAT3	260	263	PF00017	0.759
LIG_SH2_STAT3	283	286	PF00017	0.709
LIG_SH2_STAT5	32	35	PF00017	0.648
LIG_SH2_STAT5	772	775	PF00017	0.683
LIG_SH3_3	148	154	PF00018	0.819
LIG_SH3_3	336	342	PF00018	0.856
LIG_SUMO_SIM_anti_2	5	11	PF11976	0.789
LIG_SUMO_SIM_anti_2	70	78	PF11976	0.659
LIG_SUMO_SIM_par_1	5	11	PF11976	0.789
LIG_SUMO_SIM_par_1	54	61	PF11976	0.640
LIG_SUMO_SIM_par_1	681	688	PF11976	0.783
LIG_TRAF2_1	271	274	PF00917	0.728
LIG_TRAF2_1	423	426	PF00917	0.703
LIG_TRAF2_1	458	461	PF00917	0.724
LIG_TRAF2_1	546	549	PF00917	0.687
LIG_TRAF2_1	581	584	PF00917	0.714
MOD_CDK_SPK_2	338	343	PF00069	0.860
MOD_CK1_1	70	76	PF00069	0.653
MOD_CK1_1	796	802	PF00069	0.714
MOD_CK2_1	16	22	PF00069	0.782
MOD_CK2_1	172	178	PF00069	0.685
MOD_CK2_1	249	255	PF00069	0.708
MOD_CK2_1	268	274	PF00069	0.398
MOD_CK2_1	405	411	PF00069	0.716
MOD_CK2_1	528	534	PF00069	0.706
MOD_CK2_1	62	68	PF00069	0.678
MOD_CK2_1	651	657	PF00069	0.728
MOD_CK2_1	689	695	PF00069	0.752
MOD_CK2_1	782	788	PF00069	0.777
MOD_GlcNHglycan	10	13	PF01048	0.791
MOD_GlcNHglycan	233	236	PF01048	0.706
MOD_GlcNHglycan	735	739	PF01048	0.676
MOD_GSK3_1	131	138	PF00069	0.847
MOD_GSK3_1	22	29	PF00069	0.713
MOD_GSK3_1	311	318	PF00069	0.841
MOD_GSK3_1	405	412	PF00069	0.718
MOD_GSK3_1	52	59	PF00069	0.633
MOD_GSK3_1	528	535	PF00069	0.707
MOD_GSK3_1	63	70	PF00069	0.483
MOD_GSK3_1	651	658	PF00069	0.728
MOD_N-GLC_1	291	296	PF02516	0.787
MOD_N-GLC_1	671	676	PF02516	0.803
MOD_N-GLC_1	70	75	PF02516	0.656
MOD_NEK2_1	221	226	PF00069	0.706
MOD_NEK2_1	23	28	PF00069	0.708
MOD_NEK2_1	30	35	PF00069	0.523
MOD_NEK2_1	332	337	PF00069	0.853
MOD_NEK2_1	712	717	PF00069	0.729
MOD_NEK2_1	758	763	PF00069	0.678
MOD_OFUCOSY	85	91	PF10250	0.636
MOD_PIKK_1	137	143	PF00454	0.857
MOD_PIKK_1	193	199	PF00454	0.684
MOD_PIKK_1	237	243	PF00454	0.690
MOD_PIKK_1	282	288	PF00454	0.716
MOD_PIKK_1	315	321	PF00454	0.853
MOD_PIKK_1	341	347	PF00454	0.869
MOD_PK_1	671	677	PF00069	0.804
MOD_Plk_1	173	179	PF00069	0.685
MOD_Plk_1	221	227	PF00069	0.702
MOD_Plk_1	267	273	PF00069	0.732
MOD_Plk_1	70	76	PF00069	0.653
MOD_Plk_1	96	102	PF00069	0.674
MOD_Plk_2-3	268	274	PF00069	0.690
MOD_Plk_2-3	275	281	PF00069	0.636
MOD_Plk_2-3	3	9	PF00069	0.786
MOD_Plk_2-3	744	750	PF00069	0.764
MOD_Plk_2-3	782	788	PF00069	0.777
MOD_Plk_4	275	281	PF00069	0.718
MOD_Plk_4	70	76	PF00069	0.653
MOD_ProDKin_1	291	297	PF00069	0.791
MOD_ProDKin_1	338	344	PF00069	0.861
MOD_SUMO_rev_2	398	408	PF00179	0.673
MOD_SUMO_rev_2	441	446	PF00179	0.701
MOD_SUMO_rev_2	521	531	PF00179	0.664
MOD_SUMO_rev_2	564	569	PF00179	0.688
MOD_SUMO_rev_2	644	654	PF00179	0.717
TRG_DiLeu_BaEn_1	242	247	PF01217	0.703
TRG_DiLeu_BaEn_1	275	280	PF01217	0.720
TRG_DiLeu_BaEn_1	5	10	PF01217	0.790
TRG_DiLeu_BaEn_2	694	700	PF01217	0.736
TRG_DiLeu_BaLyEn_6	285	290	PF01217	0.730
TRG_DiLeu_BaLyEn_6	298	303	PF01217	0.597
TRG_ENDOCYTIC_2	116	119	PF00928	0.639
TRG_ENDOCYTIC_2	145	148	PF00928	0.832
TRG_ENDOCYTIC_2	276	279	PF00928	0.727
TRG_ENDOCYTIC_2	772	775	PF00928	0.683
TRG_ER_diArg_1	109	111	PF00400	0.641
TRG_ER_diArg_1	257	260	PF00400	0.741
TRG_ER_diArg_1	379	381	PF00400	0.733
TRG_ER_diArg_1	435	438	PF00400	0.702
TRG_ER_diArg_1	502	504	PF00400	0.716
TRG_ER_diArg_1	558	561	PF00400	0.689
TRG_ER_diArg_1	625	627	PF00400	0.723
TRG_ER_diArg_1	717	719	PF00400	0.721
TRG_NES_CRM1_1	211	222	PF08389	0.696
TRG_NES_CRM1_1	764	776	PF08389	0.683
TRG_NES_CRM1_1	8	22	PF08389	0.786
TRG_Pf-PMV_PEXEL_1	167	172	PF00026	0.704
TRG_Pf-PMV_PEXEL_1	248	253	PF00026	0.707
TRG_Pf-PMV_PEXEL_1	468	472	PF00026	0.715
TRG_Pf-PMV_PEXEL_1	591	595	PF00026	0.706
TRG_Pf-PMV_PEXEL_1	771	776	PF00026	0.690
TRG_Pf-PMV_PEXEL_1	800	804	PF00026	0.713
TRG_Pf-PMV_PEXEL_1	817	821	PF00026	0.408