Pericentrin

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Pericentrin

Gene product:

flagellar attachment zone protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HAX1_LEIBR

TriTrypDb:

LbrM.20.0620 , LbrM.20.2080 , LbrM.20.2090 , LBRM2903_200031400

Length:

1543

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 10

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HAX1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1033	1037	PF00656	0.630
CLV_C14_Caspase3-7	1130	1134	PF00656	0.628
CLV_C14_Caspase3-7	1367	1371	PF00656	0.654
CLV_C14_Caspase3-7	14	18	PF00656	0.400
CLV_C14_Caspase3-7	1492	1496	PF00656	0.756
CLV_C14_Caspase3-7	167	171	PF00656	0.413
CLV_C14_Caspase3-7	394	398	PF00656	0.484
CLV_C14_Caspase3-7	513	517	PF00656	0.445
CLV_C14_Caspase3-7	739	743	PF00656	0.757
CLV_C14_Caspase3-7	949	953	PF00656	0.711
CLV_PCSK_FUR_1	1025	1029	PF00082	0.590
CLV_PCSK_FUR_1	1359	1363	PF00082	0.619
CLV_PCSK_FUR_1	1484	1488	PF00082	0.719
CLV_PCSK_FUR_1	607	611	PF00082	0.741
CLV_PCSK_FUR_1	731	735	PF00082	0.725
CLV_PCSK_KEX2_1	1027	1029	PF00082	0.596
CLV_PCSK_KEX2_1	1124	1126	PF00082	0.588
CLV_PCSK_KEX2_1	1218	1220	PF00082	0.744
CLV_PCSK_KEX2_1	1232	1234	PF00082	0.521
CLV_PCSK_KEX2_1	1246	1248	PF00082	0.441
CLV_PCSK_KEX2_1	1260	1262	PF00082	0.422
CLV_PCSK_KEX2_1	1288	1290	PF00082	0.489
CLV_PCSK_KEX2_1	1302	1304	PF00082	0.447
CLV_PCSK_KEX2_1	1361	1363	PF00082	0.625
CLV_PCSK_KEX2_1	1486	1488	PF00082	0.725
CLV_PCSK_KEX2_1	478	480	PF00082	0.496
CLV_PCSK_KEX2_1	609	611	PF00082	0.736
CLV_PCSK_KEX2_1	674	676	PF00082	0.481
CLV_PCSK_KEX2_1	733	735	PF00082	0.731
CLV_PCSK_KEX2_1	943	945	PF00082	0.691
CLV_PCSK_PC1ET2_1	1027	1029	PF00082	0.538
CLV_PCSK_PC1ET2_1	1124	1126	PF00082	0.530
CLV_PCSK_PC1ET2_1	1218	1220	PF00082	0.717
CLV_PCSK_PC1ET2_1	1232	1234	PF00082	0.521
CLV_PCSK_PC1ET2_1	1246	1248	PF00082	0.441
CLV_PCSK_PC1ET2_1	1260	1262	PF00082	0.422
CLV_PCSK_PC1ET2_1	1288	1290	PF00082	0.489
CLV_PCSK_PC1ET2_1	1302	1304	PF00082	0.447
CLV_PCSK_PC1ET2_1	1361	1363	PF00082	0.567
CLV_PCSK_PC1ET2_1	1486	1488	PF00082	0.666
CLV_PCSK_PC1ET2_1	478	480	PF00082	0.496
CLV_PCSK_PC1ET2_1	609	611	PF00082	0.677
CLV_PCSK_PC1ET2_1	674	676	PF00082	0.472
CLV_PCSK_PC1ET2_1	733	735	PF00082	0.672
CLV_PCSK_PC1ET2_1	943	945	PF00082	0.691
CLV_PCSK_PC7_1	474	480	PF00082	0.521
CLV_PCSK_SKI1_1	114	118	PF00082	0.491
CLV_PCSK_SKI1_1	284	288	PF00082	0.455
CLV_PCSK_SKI1_1	554	558	PF00082	0.513
CLV_PCSK_SKI1_1	609	613	PF00082	0.440
CLV_PCSK_SKI1_1	815	819	PF00082	0.715
CLV_Separin_Metazoa	1534	1538	PF03568	0.416
CLV_Separin_Metazoa	781	785	PF03568	0.440
DEG_APCC_DBOX_1	113	121	PF00400	0.489
DEG_APCC_DBOX_1	485	493	PF00400	0.530
DEG_APCC_DBOX_1	645	653	PF00400	0.482
DEG_APCC_DBOX_1	894	902	PF00400	0.664
DEG_SPOP_SBC_1	138	142	PF00917	0.421
DEG_SPOP_SBC_1	853	857	PF00917	0.840
DOC_ANK_TNKS_1	1060	1067	PF00023	0.565
DOC_ANK_TNKS_1	1157	1164	PF00023	0.585
DOC_ANK_TNKS_1	1394	1401	PF00023	0.580
DOC_ANK_TNKS_1	1519	1526	PF00023	0.687
DOC_ANK_TNKS_1	766	773	PF00023	0.693
DOC_CKS1_1	220	225	PF01111	0.421
DOC_CYCLIN_RxL_1	108	121	PF00134	0.470
DOC_MAPK_gen_1	122	131	PF00069	0.400
DOC_MAPK_gen_1	239	248	PF00069	0.461
DOC_MAPK_gen_1	484	491	PF00069	0.479
DOC_PIKK_1	820	827	PF02985	0.683
DOC_PP2B_LxvP_1	368	371	PF13499	0.500
DOC_USP7_MATH_1	138	142	PF00917	0.421
DOC_USP7_MATH_1	339	343	PF00917	0.518
DOC_USP7_MATH_1	398	402	PF00917	0.597
DOC_USP7_MATH_1	496	500	PF00917	0.491
DOC_USP7_MATH_1	570	574	PF00917	0.469
DOC_USP7_MATH_1	59	63	PF00917	0.508
DOC_USP7_MATH_1	626	630	PF00917	0.602
DOC_USP7_MATH_1	802	806	PF00917	0.733
DOC_USP7_MATH_1	845	849	PF00917	0.856
DOC_USP7_MATH_1	882	886	PF00917	0.621
DOC_USP7_MATH_1	904	908	PF00917	0.693
DOC_USP7_MATH_1	910	914	PF00917	0.589
DOC_USP7_MATH_2	280	286	PF00917	0.482
DOC_USP7_UBL2_3	63	67	PF12436	0.481
DOC_WW_Pin1_4	219	224	PF00397	0.419
DOC_WW_Pin1_4	622	627	PF00397	0.567
DOC_WW_Pin1_4	637	642	PF00397	0.544
DOC_WW_Pin1_4	943	948	PF00397	0.635
LIG_14-3-3_CanoR_1	152	161	PF00244	0.408
LIG_14-3-3_CanoR_1	334	339	PF00244	0.511
LIG_14-3-3_CanoR_1	497	505	PF00244	0.469
LIG_14-3-3_CanoR_1	844	853	PF00244	0.853
LIG_Actin_WH2_2	139	154	PF00022	0.415
LIG_Actin_WH2_2	568	585	PF00022	0.434
LIG_BIR_II_1	1	5	PF00653	0.415
LIG_BIR_III_4	1036	1040	PF00653	0.630
LIG_BIR_III_4	1133	1137	PF00653	0.645
LIG_BIR_III_4	1370	1374	PF00653	0.655
LIG_BIR_III_4	1495	1499	PF00653	0.757
LIG_BIR_III_4	742	746	PF00653	0.758
LIG_BRCT_BRCA1_1	11	15	PF00533	0.350
LIG_BRCT_BRCA1_1	314	318	PF00533	0.500
LIG_BRCT_BRCA1_1	336	340	PF00533	0.514
LIG_BRCT_BRCA1_1	859	863	PF00533	0.739
LIG_Clathr_ClatBox_1	407	411	PF01394	0.492
LIG_CSK_EPIYA_1	647	651	PF00017	0.538
LIG_deltaCOP1_diTrp_1	21	24	PF00928	0.351
LIG_FHA_1	1038	1044	PF00498	0.635
LIG_FHA_1	1135	1141	PF00498	0.665
LIG_FHA_1	1372	1378	PF00498	0.603
LIG_FHA_1	1497	1503	PF00498	0.763
LIG_FHA_1	281	287	PF00498	0.474
LIG_FHA_1	326	332	PF00498	0.522
LIG_FHA_1	545	551	PF00498	0.443
LIG_FHA_1	744	750	PF00498	0.763
LIG_FHA_1	900	906	PF00498	0.625
LIG_FHA_2	1070	1076	PF00498	0.610
LIG_FHA_2	1167	1173	PF00498	0.623
LIG_FHA_2	1404	1410	PF00498	0.621
LIG_FHA_2	1529	1535	PF00498	0.717
LIG_FHA_2	28	34	PF00498	0.400
LIG_FHA_2	325	331	PF00498	0.510
LIG_FHA_2	353	359	PF00498	0.623
LIG_FHA_2	44	50	PF00498	0.352
LIG_FHA_2	502	508	PF00498	0.665
LIG_FHA_2	51	57	PF00498	0.453
LIG_FHA_2	651	657	PF00498	0.749
LIG_FHA_2	776	782	PF00498	0.730
LIG_FHA_2	85	91	PF00498	0.562
LIG_FHA_2	93	99	PF00498	0.481
LIG_FHA_2	944	950	PF00498	0.641
LIG_LIR_Apic_2	336	341	PF02991	0.623
LIG_LIR_Apic_2	931	935	PF02991	0.625
LIG_LIR_Gen_1	12	18	PF02991	0.345
LIG_LIR_Gen_1	158	169	PF02991	0.395
LIG_LIR_Gen_1	586	595	PF02991	0.415
LIG_LIR_Nem_3	12	16	PF02991	0.318
LIG_LIR_Nem_3	158	164	PF02991	0.384
LIG_LIR_Nem_3	2	6	PF02991	0.353
LIG_LIR_Nem_3	264	270	PF02991	0.412
LIG_LIR_Nem_3	586	591	PF02991	0.400
LIG_LIR_Nem_3	866	871	PF02991	0.754
LIG_LIR_Nem_3	931	937	PF02991	0.632
LIG_LYPXL_yS_3	934	937	PF13949	0.637
LIG_MYND_3	1041	1045	PF01753	0.582
LIG_MYND_3	1138	1142	PF01753	0.619
LIG_MYND_3	1375	1379	PF01753	0.608
LIG_MYND_3	1500	1504	PF01753	0.710
LIG_MYND_3	747	751	PF01753	0.709
LIG_NRBOX	1531	1537	PF00104	0.654
LIG_NRBOX	405	411	PF00104	0.490
LIG_NRBOX	778	784	PF00104	0.672
LIG_PDZ_Class_3	1538	1543	PF00595	0.438
LIG_Rb_LxCxE_1	212	232	PF01857	0.419
LIG_RPA_C_Fungi	105	117	PF08784	0.462
LIG_SH2_CRK	588	592	PF00017	0.414
LIG_SH2_CRK	932	936	PF00017	0.630
LIG_SH2_PTP2	3	6	PF00017	0.351
LIG_SH2_STAP1	1069	1073	PF00017	0.620
LIG_SH2_STAP1	1166	1170	PF00017	0.632
LIG_SH2_STAP1	1403	1407	PF00017	0.630
LIG_SH2_STAP1	1528	1532	PF00017	0.719
LIG_SH2_STAP1	399	403	PF00017	0.490
LIG_SH2_STAP1	501	505	PF00017	0.663
LIG_SH2_STAP1	588	592	PF00017	0.414
LIG_SH2_STAP1	650	654	PF00017	0.760
LIG_SH2_STAP1	775	779	PF00017	0.730
LIG_SH2_STAP1	941	945	PF00017	0.688
LIG_SH2_STAT3	508	511	PF00017	0.519
LIG_SH2_STAT3	539	542	PF00017	0.463
LIG_SH2_STAT5	3	6	PF00017	0.351
LIG_SH2_STAT5	422	425	PF00017	0.518
LIG_SH3_3	217	223	PF00018	0.413
LIG_SH3_3	317	323	PF00018	0.457
LIG_SH3_3	632	638	PF00018	0.650
LIG_SUMO_SIM_anti_2	100	107	PF11976	0.491
LIG_SUMO_SIM_anti_2	140	149	PF11976	0.420
LIG_SUMO_SIM_anti_2	405	411	PF11976	0.490
LIG_SUMO_SIM_anti_2	804	812	PF11976	0.727
LIG_SUMO_SIM_par_1	405	411	PF11976	0.490
LIG_TRAF2_1	1072	1075	PF00917	0.609
LIG_TRAF2_1	1169	1172	PF00917	0.622
LIG_TRAF2_1	1406	1409	PF00917	0.621
LIG_TRAF2_1	1531	1534	PF00917	0.718
LIG_TRAF2_1	1538	1541	PF00917	0.596
LIG_TRAF2_1	165	168	PF00917	0.470
LIG_TRAF2_1	171	174	PF00917	0.475
LIG_TRAF2_1	653	656	PF00917	0.748
LIG_TRAF2_1	68	71	PF00917	0.401
LIG_TRAF2_1	778	781	PF00917	0.731
LIG_TRAF2_1	785	788	PF00917	0.634
LIG_TRAF2_1	88	91	PF00917	0.571
LIG_TRAF2_1	95	98	PF00917	0.475
LIG_TRAF2_1	967	970	PF00917	0.737
LIG_TRAF2_2	1060	1065	PF00917	0.624
LIG_TRAF2_2	1394	1399	PF00917	0.524
LIG_TRAF2_2	1519	1524	PF00917	0.752
LIG_TRAF2_2	766	771	PF00917	0.757
LIG_TYR_ITIM	11	16	PF00017	0.407
LIG_UBA3_1	116	124	PF00899	0.484
LIG_UBA3_1	406	412	PF00899	0.589
LIG_UBA3_1	575	583	PF00899	0.470
LIG_UBA3_1	807	815	PF00899	0.724
MOD_CDK_SPK_2	943	948	PF00069	0.635
MOD_CK1_1	141	147	PF00069	0.377
MOD_CK1_1	155	161	PF00069	0.372
MOD_CK1_1	234	240	PF00069	0.433
MOD_CK1_1	258	264	PF00069	0.399
MOD_CK1_1	625	631	PF00069	0.600
MOD_CK1_1	82	88	PF00069	0.576
MOD_CK1_1	857	863	PF00069	0.807
MOD_CK1_1	899	905	PF00069	0.623
MOD_CK1_1	9	15	PF00069	0.350
MOD_CK1_1	918	924	PF00069	0.419
MOD_CK2_1	1069	1075	PF00069	0.615
MOD_CK2_1	1166	1172	PF00069	0.627
MOD_CK2_1	1403	1409	PF00069	0.625
MOD_CK2_1	1528	1534	PF00069	0.718
MOD_CK2_1	162	168	PF00069	0.467
MOD_CK2_1	324	330	PF00069	0.493
MOD_CK2_1	424	430	PF00069	0.500
MOD_CK2_1	43	49	PF00069	0.390
MOD_CK2_1	50	56	PF00069	0.463
MOD_CK2_1	501	507	PF00069	0.589
MOD_CK2_1	59	65	PF00069	0.454
MOD_CK2_1	626	632	PF00069	0.606
MOD_CK2_1	637	643	PF00069	0.650
MOD_CK2_1	650	656	PF00069	0.716
MOD_CK2_1	775	781	PF00069	0.730
MOD_CK2_1	84	90	PF00069	0.610
MOD_CK2_1	92	98	PF00069	0.495
MOD_GlcNHglycan	231	234	PF01048	0.492
MOD_GlcNHglycan	249	252	PF01048	0.371
MOD_GlcNHglycan	314	317	PF01048	0.498
MOD_GlcNHglycan	425	429	PF01048	0.498
MOD_GlcNHglycan	618	622	PF01048	0.502
MOD_GlcNHglycan	632	635	PF01048	0.577
MOD_GlcNHglycan	686	691	PF01048	0.484
MOD_GSK3_1	137	144	PF00069	0.414
MOD_GSK3_1	312	319	PF00069	0.494
MOD_GSK3_1	387	394	PF00069	0.475
MOD_GSK3_1	416	423	PF00069	0.506
MOD_GSK3_1	43	50	PF00069	0.410
MOD_GSK3_1	54	61	PF00069	0.490
MOD_GSK3_1	544	551	PF00069	0.443
MOD_GSK3_1	622	629	PF00069	0.576
MOD_GSK3_1	853	860	PF00069	0.832
MOD_GSK3_1	867	874	PF00069	0.501
MOD_GSK3_1	93	100	PF00069	0.489
MOD_N-GLC_1	110	115	PF02516	0.451
MOD_N-GLC_1	218	223	PF02516	0.415
MOD_N-GLC_1	416	421	PF02516	0.500
MOD_N-GLC_1	845	850	PF02516	0.858
MOD_NEK2_1	146	151	PF00069	0.422
MOD_NEK2_1	318	323	PF00069	0.510
MOD_NEK2_1	424	429	PF00069	0.501
MOD_NEK2_1	435	440	PF00069	0.478
MOD_NEK2_1	541	546	PF00069	0.445
MOD_NEK2_1	575	580	PF00069	0.457
MOD_NEK2_1	6	11	PF00069	0.409
MOD_NEK2_1	811	816	PF00069	0.429
MOD_PIKK_1	152	158	PF00454	0.338
MOD_PIKK_1	435	441	PF00454	0.484
MOD_PIKK_1	541	547	PF00454	0.444
MOD_PIKK_1	79	85	PF00454	0.533
MOD_PIKK_1	93	99	PF00454	0.446
MOD_PK_1	124	130	PF00069	0.395
MOD_PKA_2	333	339	PF00069	0.452
MOD_PKA_2	496	502	PF00069	0.451
MOD_PKA_2	85	91	PF00069	0.594
MOD_PKA_2	857	863	PF00069	0.807
MOD_PKA_2	93	99	PF00069	0.504
MOD_Plk_1	261	267	PF00069	0.465
MOD_Plk_1	316	322	PF00069	0.509
MOD_Plk_1	388	394	PF00069	0.539
MOD_Plk_1	416	422	PF00069	0.504
MOD_Plk_1	424	430	PF00069	0.459
MOD_Plk_1	47	53	PF00069	0.420
MOD_Plk_1	480	486	PF00069	0.468
MOD_Plk_1	601	607	PF00069	0.448
MOD_Plk_1	899	905	PF00069	0.621
MOD_Plk_2-3	168	174	PF00069	0.492
MOD_Plk_4	124	130	PF00069	0.395
MOD_Plk_4	146	152	PF00069	0.419
MOD_Plk_4	231	237	PF00069	0.437
MOD_Plk_4	255	261	PF00069	0.403
MOD_Plk_4	271	277	PF00069	0.466
MOD_Plk_4	282	288	PF00069	0.400
MOD_Plk_4	47	53	PF00069	0.420
MOD_Plk_4	575	581	PF00069	0.417
MOD_Plk_4	6	12	PF00069	0.409
MOD_Plk_4	867	873	PF00069	0.689
MOD_Plk_4	904	910	PF00069	0.634
MOD_ProDKin_1	219	225	PF00069	0.419
MOD_ProDKin_1	622	628	PF00069	0.572
MOD_ProDKin_1	637	643	PF00069	0.536
MOD_ProDKin_1	943	949	PF00069	0.638
MOD_SUMO_for_1	817	820	PF00179	0.718
MOD_SUMO_for_1	967	970	PF00179	0.737
MOD_SUMO_rev_2	1214	1220	PF00179	0.726
MOD_SUMO_rev_2	1228	1234	PF00179	0.530
MOD_SUMO_rev_2	1242	1248	PF00179	0.456
MOD_SUMO_rev_2	1284	1290	PF00179	0.499
MOD_SUMO_rev_2	1298	1304	PF00179	0.456
MOD_SUMO_rev_2	281	286	PF00179	0.479
MOD_SUMO_rev_2	548	556	PF00179	0.630
MOD_SUMO_rev_2	61	68	PF00179	0.484
MOD_SUMO_rev_2	670	676	PF00179	0.493
MOD_SUMO_rev_2	684	690	PF00179	0.529
TRG_DiLeu_BaEn_1	101	106	PF01217	0.493
TRG_DiLeu_BaEn_1	402	407	PF01217	0.476
TRG_DiLeu_BaEn_1	531	536	PF01217	0.445
TRG_DiLeu_BaLyEn_6	69	74	PF01217	0.460
TRG_ENDOCYTIC_2	13	16	PF00928	0.375
TRG_ENDOCYTIC_2	3	6	PF00928	0.380
TRG_ENDOCYTIC_2	588	591	PF00928	0.409
TRG_ENDOCYTIC_2	934	937	PF00928	0.637
TRG_ER_diArg_1	1536	1539	PF00400	0.415
TRG_ER_diArg_1	783	786	PF00400	0.447
TRG_NES_CRM1_1	548	563	PF08389	0.487
TRG_NLS_MonoExtN_4	607	613	PF00514	0.445
TRG_Pf-PMV_PEXEL_1	1061	1065	PF00026	0.606
TRG_Pf-PMV_PEXEL_1	114	119	PF00026	0.494
TRG_Pf-PMV_PEXEL_1	1158	1162	PF00026	0.627
TRG_Pf-PMV_PEXEL_1	1395	1399	PF00026	0.622
TRG_Pf-PMV_PEXEL_1	152	156	PF00026	0.335
TRG_Pf-PMV_PEXEL_1	1520	1524	PF00026	0.733
TRG_Pf-PMV_PEXEL_1	460	464	PF00026	0.517
TRG_Pf-PMV_PEXEL_1	468	472	PF00026	0.541
TRG_Pf-PMV_PEXEL_1	767	771	PF00026	0.738

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HAX0	Leishmania braziliensis	75%	100%
A4IA29	Leishmania infantum	50%	85%