G_PROTEIN_RECEP_F1_2 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HAW0_LEIBR

TriTrypDb:

LbrM.20.1990

Length:

236

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4HAW0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HAW0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	138	140	PF00675	0.602
CLV_NRD_NRD_1	219	221	PF00675	0.649
CLV_NRD_NRD_1	26	28	PF00675	0.534
CLV_NRD_NRD_1	64	66	PF00675	0.740
CLV_PCSK_FUR_1	217	221	PF00082	0.650
CLV_PCSK_KEX2_1	138	140	PF00082	0.602
CLV_PCSK_KEX2_1	219	221	PF00082	0.649
CLV_PCSK_KEX2_1	25	27	PF00082	0.536
CLV_PCSK_KEX2_1	63	65	PF00082	0.748
CLV_PCSK_SKI1_1	118	122	PF00082	0.536
CLV_PCSK_SKI1_1	133	137	PF00082	0.405
CLV_PCSK_SKI1_1	139	143	PF00082	0.523
CLV_PCSK_SKI1_1	153	157	PF00082	0.368
CLV_PCSK_SKI1_1	222	226	PF00082	0.656
CLV_PCSK_SKI1_1	29	33	PF00082	0.449
DEG_APCC_DBOX_1	205	213	PF00400	0.832
DEG_APCC_DBOX_1	24	32	PF00400	0.727
DEG_SPOP_SBC_1	19	23	PF00917	0.537
DEG_SPOP_SBC_1	2	6	PF00917	0.798
DOC_MAPK_gen_1	107	117	PF00069	0.754
DOC_MAPK_gen_1	25	32	PF00069	0.726
DOC_MAPK_HePTP_8	90	102	PF00069	0.549
DOC_MAPK_MEF2A_6	25	32	PF00069	0.726
DOC_MAPK_MEF2A_6	93	102	PF00069	0.549
DOC_MAPK_NFAT4_5	25	33	PF00069	0.721
DOC_MAPK_RevD_3	124	139	PF00069	0.778
DOC_PP1_RVXF_1	116	123	PF00149	0.737
DOC_USP7_MATH_1	111	115	PF00917	0.750
DOC_USP7_MATH_1	17	21	PF00917	0.577
DOC_USP7_MATH_1	2	6	PF00917	0.798
DOC_WW_Pin1_4	164	169	PF00397	0.836
DOC_WW_Pin1_4	224	229	PF00397	0.850
LIG_14-3-3_CanoR_1	110	116	PF00244	0.539
LIG_14-3-3_CanoR_1	180	189	PF00244	0.834
LIG_14-3-3_CanoR_1	206	210	PF00244	0.833
LIG_14-3-3_CanoR_1	222	231	PF00244	0.652
LIG_14-3-3_CanoR_1	71	81	PF00244	0.519
LIG_14-3-3_CanoR_1	93	101	PF00244	0.549
LIG_14-3-3_CterR_2	232	236	PF00244	0.840
LIG_EH1_1	81	89	PF00400	0.449
LIG_eIF4E_1	82	88	PF01652	0.449
LIG_FHA_1	32	38	PF00498	0.549
LIG_FHA_1	40	46	PF00498	0.410
LIG_FHA_1	95	101	PF00498	0.549
LIG_FHA_2	209	215	PF00498	0.835
LIG_LIR_Gen_1	34	43	PF02991	0.549
LIG_LIR_Nem_3	150	155	PF02991	0.810
LIG_LIR_Nem_3	34	38	PF02991	0.549
LIG_NRBOX	116	122	PF00104	0.740
LIG_PCNA_yPIPBox_3	12	26	PF02747	0.755
LIG_Pex14_2	44	48	PF04695	0.549
LIG_SH2_CRK	152	156	PF00017	0.814
LIG_SH2_PTP2	82	85	PF00017	0.449
LIG_SH2_SRC	82	85	PF00017	0.449
LIG_SH2_STAT5	82	85	PF00017	0.449
LIG_SH3_3	162	168	PF00018	0.839
LIG_SUMO_SIM_anti_2	97	102	PF11976	0.549
LIG_SUMO_SIM_par_1	87	92	PF11976	0.549
LIG_TYR_ITIM	80	85	PF00017	0.654
LIG_WRC_WIRS_1	32	37	PF05994	0.549
LIG_WW_3	163	167	PF00397	0.816
MOD_CK1_1	167	173	PF00069	0.832
MOD_CK1_1	20	26	PF00069	0.396
MOD_CK1_1	227	233	PF00069	0.826
MOD_CK1_1	4	10	PF00069	0.723
MOD_CK1_1	72	78	PF00069	0.646
MOD_CK2_1	204	210	PF00069	0.806
MOD_CMANNOS	119	122	PF00535	0.668
MOD_GlcNHglycan	143	146	PF01048	0.756
MOD_GlcNHglycan	169	172	PF01048	0.839
MOD_GlcNHglycan	6	9	PF01048	0.716
MOD_GSK3_1	17	24	PF00069	0.431
MOD_GSK3_1	2	9	PF00069	0.741
MOD_GSK3_1	204	211	PF00069	0.806
MOD_GSK3_1	48	55	PF00069	0.663
MOD_N-GLC_1	222	227	PF02516	0.838
MOD_N-GLC_1	72	77	PF02516	0.648
MOD_NEK2_1	155	160	PF00069	0.796
MOD_NEK2_1	18	23	PF00069	0.696
MOD_NEK2_1	196	201	PF00069	0.810
MOD_NEK2_1	57	62	PF00069	0.661
MOD_NEK2_1	94	99	PF00069	0.549
MOD_PKA_2	205	211	PF00069	0.806
MOD_PKA_2	92	98	PF00069	0.549
MOD_PKB_1	220	228	PF00069	0.834
MOD_Plk_1	52	58	PF00069	0.670
MOD_Plk_4	111	117	PF00069	0.690
MOD_ProDKin_1	164	170	PF00069	0.815
MOD_ProDKin_1	224	230	PF00069	0.832
TRG_DiLeu_BaLyEn_6	183	188	PF01217	0.805
TRG_ENDOCYTIC_2	152	155	PF00928	0.777
TRG_ENDOCYTIC_2	81	84	PF00928	0.655
TRG_ER_diArg_1	137	139	PF00400	0.763
TRG_ER_diArg_1	219	222	PF00400	0.833
TRG_ER_diArg_1	231	234	PF00400	0.610
TRG_ER_diArg_1	25	27	PF00400	0.671
TRG_ER_diArg_1	63	65	PF00400	0.688
TRG_Pf-PMV_PEXEL_1	153	157	PF00026	0.785