Mitochondrial RNA binding complex 1 subunit

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HAV1_LEIBR

TriTrypDb:

LbrM.20.1900 , LBRM2903_200029700

Length:

334

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HAV1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HAV1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	305	309	PF00656	0.582
CLV_NRD_NRD_1	125	127	PF00675	0.689
CLV_NRD_NRD_1	207	209	PF00675	0.448
CLV_NRD_NRD_1	219	221	PF00675	0.356
CLV_NRD_NRD_1	225	227	PF00675	0.375
CLV_NRD_NRD_1	328	330	PF00675	0.620
CLV_NRD_NRD_1	7	9	PF00675	0.590
CLV_PCSK_KEX2_1	125	127	PF00082	0.650
CLV_PCSK_KEX2_1	219	221	PF00082	0.355
CLV_PCSK_KEX2_1	225	227	PF00082	0.372
CLV_PCSK_KEX2_1	328	330	PF00082	0.566
CLV_PCSK_KEX2_1	7	9	PF00082	0.603
CLV_PCSK_PC7_1	3	9	PF00082	0.687
CLV_PCSK_SKI1_1	15	19	PF00082	0.662
CLV_PCSK_SKI1_1	159	163	PF00082	0.463
CLV_PCSK_SKI1_1	209	213	PF00082	0.455
CLV_PCSK_SKI1_1	219	223	PF00082	0.427
CLV_PCSK_SKI1_1	299	303	PF00082	0.475
DEG_Nend_Nbox_1	1	3	PF02207	0.674
DOC_MAPK_DCC_7	126	136	PF00069	0.582
DOC_MAPK_FxFP_2	17	20	PF00069	0.620
DOC_MAPK_gen_1	208	215	PF00069	0.417
DOC_PP1_RVXF_1	194	201	PF00149	0.461
DOC_PP4_FxxP_1	17	20	PF00568	0.663
DOC_USP7_MATH_1	24	28	PF00917	0.636
DOC_USP7_MATH_1	307	311	PF00917	0.614
DOC_USP7_UBL2_3	159	163	PF12436	0.341
DOC_WW_Pin1_4	20	25	PF00397	0.627
DOC_WW_Pin1_4	99	104	PF00397	0.655
LIG_14-3-3_CanoR_1	133	139	PF00244	0.649
LIG_14-3-3_CanoR_1	299	304	PF00244	0.478
LIG_14-3-3_CanoR_1	315	321	PF00244	0.374
LIG_APCC_ABBA_1	151	156	PF00400	0.552
LIG_Clathr_ClatBox_1	148	152	PF01394	0.518
LIG_Clathr_ClatBox_1	57	61	PF01394	0.718
LIG_eIF4E_1	138	144	PF01652	0.445
LIG_eIF4E_1	95	101	PF01652	0.555
LIG_FHA_1	26	32	PF00498	0.594
LIG_FHA_1	271	277	PF00498	0.395
LIG_FHA_1	315	321	PF00498	0.424
LIG_FHA_2	243	249	PF00498	0.489
LIG_FHA_2	276	282	PF00498	0.470
LIG_FHA_2	300	306	PF00498	0.507
LIG_FHA_2	322	328	PF00498	0.584
LIG_KLC1_Yacidic_2	92	97	PF13176	0.640
LIG_LIR_Apic_2	14	20	PF02991	0.636
LIG_LIR_Apic_2	181	187	PF02991	0.549
LIG_LIR_Apic_2	63	68	PF02991	0.641
LIG_LIR_Apic_2	92	98	PF02991	0.532
LIG_LIR_Gen_1	118	128	PF02991	0.694
LIG_LIR_Gen_1	248	257	PF02991	0.536
LIG_LIR_Gen_1	266	274	PF02991	0.441
LIG_LIR_Gen_1	283	294	PF02991	0.285
LIG_LIR_Nem_3	118	123	PF02991	0.526
LIG_LIR_Nem_3	199	203	PF02991	0.504
LIG_LIR_Nem_3	248	252	PF02991	0.448
LIG_LIR_Nem_3	266	270	PF02991	0.325
LIG_LIR_Nem_3	282	288	PF02991	0.380
LIG_LIR_Nem_3	76	82	PF02991	0.595
LIG_MAD2	196	204	PF02301	0.575
LIG_PCNA_yPIPBox_3	261	275	PF02747	0.492
LIG_Pex14_1	180	184	PF04695	0.558
LIG_SH2_CRK	34	38	PF00017	0.533
LIG_SH2_PTP2	267	270	PF00017	0.519
LIG_SH2_SRC	184	187	PF00017	0.533
LIG_SH2_SRC	265	268	PF00017	0.512
LIG_SH2_SRC	47	50	PF00017	0.607
LIG_SH2_SRC	95	98	PF00017	0.545
LIG_SH2_STAP1	316	320	PF00017	0.413
LIG_SH2_STAT3	258	261	PF00017	0.448
LIG_SH2_STAT5	184	187	PF00017	0.533
LIG_SH2_STAT5	267	270	PF00017	0.528
LIG_SH2_STAT5	285	288	PF00017	0.299
LIG_SH2_STAT5	316	319	PF00017	0.416
LIG_SH2_STAT5	47	50	PF00017	0.607
LIG_SH2_STAT5	79	82	PF00017	0.504
LIG_SH2_STAT5	95	98	PF00017	0.545
LIG_SH3_3	200	206	PF00018	0.571
LIG_SH3_CIN85_PxpxPR_1	128	133	PF14604	0.644
LIG_Sin3_3	211	218	PF02671	0.391
LIG_SUMO_SIM_anti_2	232	239	PF11976	0.538
LIG_SUMO_SIM_par_1	107	113	PF11976	0.523
LIG_SUMO_SIM_par_1	316	321	PF11976	0.414
LIG_SUMO_SIM_par_1	55	61	PF11976	0.719
LIG_TRAF2_1	102	105	PF00917	0.536
LIG_UBA3_1	214	222	PF00899	0.508
LIG_WRC_WIRS_1	249	254	PF05994	0.317
MOD_CK1_1	310	316	PF00069	0.568
MOD_CK2_1	226	232	PF00069	0.421
MOD_CK2_1	99	105	PF00069	0.542
MOD_Cter_Amidation	5	8	PF01082	0.749
MOD_GlcNHglycan	181	184	PF01048	0.586
MOD_GlcNHglycan	193	196	PF01048	0.406
MOD_GlcNHglycan	258	261	PF01048	0.526
MOD_GlcNHglycan	299	302	PF01048	0.596
MOD_GlcNHglycan	54	57	PF01048	0.580
MOD_GSK3_1	134	141	PF00069	0.610
MOD_GSK3_1	20	27	PF00069	0.635
MOD_GSK3_1	238	245	PF00069	0.371
MOD_GSK3_1	297	304	PF00069	0.525
MOD_GSK3_1	310	317	PF00069	0.370
MOD_LATS_1	224	230	PF00433	0.361
MOD_NEK2_1	110	115	PF00069	0.517
MOD_NEK2_1	134	139	PF00069	0.648
MOD_NEK2_1	179	184	PF00069	0.648
MOD_NEK2_1	25	30	PF00069	0.728
MOD_NEK2_1	270	275	PF00069	0.493
MOD_PIKK_1	41	47	PF00454	0.601
MOD_PKA_2	134	140	PF00069	0.637
MOD_PKA_2	314	320	PF00069	0.423
MOD_Plk_1	167	173	PF00069	0.453
MOD_Plk_1	281	287	PF00069	0.475
MOD_Plk_1	60	66	PF00069	0.600
MOD_Plk_2-3	281	287	PF00069	0.481
MOD_Plk_4	168	174	PF00069	0.488
MOD_Plk_4	242	248	PF00069	0.501
MOD_Plk_4	281	287	PF00069	0.466
MOD_Plk_4	60	66	PF00069	0.630
MOD_ProDKin_1	20	26	PF00069	0.626
MOD_ProDKin_1	99	105	PF00069	0.654
MOD_SUMO_for_1	161	164	PF00179	0.566
MOD_SUMO_for_1	279	282	PF00179	0.494
TRG_DiLeu_BaEn_1	104	109	PF01217	0.508
TRG_DiLeu_BaEn_1	146	151	PF01217	0.432
TRG_ENDOCYTIC_2	265	268	PF00928	0.528
TRG_ENDOCYTIC_2	34	37	PF00928	0.539
TRG_ENDOCYTIC_2	79	82	PF00928	0.504
TRG_ER_diArg_1	125	127	PF00400	0.689
TRG_ER_diArg_1	132	135	PF00400	0.539
TRG_ER_diArg_1	218	220	PF00400	0.396
TRG_ER_diArg_1	328	330	PF00400	0.659
TRG_ER_diArg_1	7	9	PF00400	0.604
TRG_NLS_MonoExtN_4	206	212	PF00514	0.526
TRG_Pf-PMV_PEXEL_1	142	146	PF00026	0.510
TRG_Pf-PMV_PEXEL_1	7	12	PF00026	0.673

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I3R0	Leptomonas seymouri	79%	100%
A0A0S4INW7	Bodo saltans	53%	99%
A0A1X0P9M5	Trypanosomatidae	64%	100%
A0A3S7X7Z6	Leishmania donovani	93%	100%
A4I9Z8	Leishmania infantum	93%	100%
C9ZML5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	66%	100%
E9B526	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q4Q2W0	Leishmania major	93%	100%
V5DGS2	Trypanosoma cruzi	63%	100%