Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HAU9_LEIBR

TriTrypDb:

LbrM.20.1880 , LBRM2903_200029500

Length:

363

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HAU9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HAU9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	287	291	PF00656	0.734
CLV_C14_Caspase3-7	50	54	PF00656	0.562
CLV_NRD_NRD_1	298	300	PF00675	0.802
CLV_NRD_NRD_1	316	318	PF00675	0.523
CLV_NRD_NRD_1	44	46	PF00675	0.704
CLV_PCSK_FUR_1	42	46	PF00082	0.611
CLV_PCSK_KEX2_1	298	300	PF00082	0.802
CLV_PCSK_KEX2_1	315	317	PF00082	0.535
CLV_PCSK_KEX2_1	44	46	PF00082	0.704
CLV_PCSK_PC1ET2_1	44	46	PF00082	0.704
CLV_PCSK_SKI1_1	132	136	PF00082	0.707
CLV_PCSK_SKI1_1	17	21	PF00082	0.657
CLV_PCSK_SKI1_1	275	279	PF00082	0.551
CLV_PCSK_SKI1_1	6	10	PF00082	0.732
DEG_APCC_DBOX_1	131	139	PF00400	0.529
DEG_Nend_UBRbox_3	1	3	PF02207	0.790
DEG_SCF_FBW7_1	7	13	PF00400	0.537
DEG_SPOP_SBC_1	330	334	PF00917	0.581
DOC_CKS1_1	7	12	PF01111	0.791
DOC_CYCLIN_RxL_1	14	23	PF00134	0.564
DOC_MAPK_gen_1	298	305	PF00069	0.801
DOC_USP7_MATH_1	10	14	PF00917	0.564
DOC_USP7_MATH_1	152	156	PF00917	0.578
DOC_USP7_MATH_1	323	327	PF00917	0.592
DOC_USP7_MATH_1	330	334	PF00917	0.554
DOC_USP7_MATH_1	35	39	PF00917	0.670
DOC_USP7_MATH_1	84	88	PF00917	0.701
DOC_WW_Pin1_4	246	251	PF00397	0.631
DOC_WW_Pin1_4	31	36	PF00397	0.743
DOC_WW_Pin1_4	350	355	PF00397	0.737
DOC_WW_Pin1_4	6	11	PF00397	0.687
DOC_WW_Pin1_4	92	97	PF00397	0.605
LIG_14-3-3_CanoR_1	167	177	PF00244	0.617
LIG_14-3-3_CanoR_1	195	201	PF00244	0.761
LIG_14-3-3_CanoR_1	29	35	PF00244	0.839
LIG_14-3-3_CanoR_1	298	302	PF00244	0.804
LIG_14-3-3_CanoR_1	88	96	PF00244	0.662
LIG_APCC_ABBAyCdc20_2	17	23	PF00400	0.828
LIG_BRCT_BRCA1_1	140	144	PF00533	0.793
LIG_FHA_1	160	166	PF00498	0.762
LIG_FHA_1	274	280	PF00498	0.553
LIG_FHA_2	201	207	PF00498	0.778
LIG_FHA_2	247	253	PF00498	0.593
LIG_LIR_Nem_3	219	225	PF02991	0.557
LIG_NRP_CendR_1	360	363	PF00754	0.755
LIG_PTB_Apo_2	104	111	PF02174	0.555
LIG_PTB_Phospho_1	104	110	PF10480	0.556
LIG_SH2_STAT3	198	201	PF00017	0.823
LIG_SH2_STAT5	238	241	PF00017	0.509
LIG_SUMO_SIM_anti_2	65	71	PF11976	0.528
LIG_TRAF2_1	259	262	PF00917	0.816
MOD_CDK_SPK_2	31	36	PF00069	0.743
MOD_CDK_SPK_2	355	360	PF00069	0.575
MOD_CDK_SPK_2	92	97	PF00069	0.575
MOD_CK1_1	106	112	PF00069	0.544
MOD_CK1_1	124	130	PF00069	0.570
MOD_CK1_1	194	200	PF00069	0.825
MOD_CK1_1	256	262	PF00069	0.646
MOD_CK1_1	304	310	PF00069	0.715
MOD_CK1_1	31	37	PF00069	0.648
MOD_CK1_1	332	338	PF00069	0.692
MOD_CK1_1	38	44	PF00069	0.613
MOD_CK1_1	76	82	PF00069	0.757
MOD_CK1_1	87	93	PF00069	0.728
MOD_CK1_1	95	101	PF00069	0.718
MOD_CK2_1	200	206	PF00069	0.785
MOD_CK2_1	256	262	PF00069	0.601
MOD_CK2_1	44	50	PF00069	0.572
MOD_GlcNHglycan	12	15	PF01048	0.536
MOD_GlcNHglycan	140	143	PF01048	0.805
MOD_GlcNHglycan	156	159	PF01048	0.564
MOD_GlcNHglycan	258	261	PF01048	0.723
MOD_GlcNHglycan	310	313	PF01048	0.583
MOD_GlcNHglycan	37	40	PF01048	0.686
MOD_GSK3_1	117	124	PF00069	0.615
MOD_GSK3_1	187	194	PF00069	0.632
MOD_GSK3_1	196	203	PF00069	0.673
MOD_GSK3_1	284	291	PF00069	0.614
MOD_GSK3_1	297	304	PF00069	0.697
MOD_GSK3_1	31	38	PF00069	0.781
MOD_GSK3_1	329	336	PF00069	0.703
MOD_GSK3_1	350	357	PF00069	0.567
MOD_GSK3_1	45	52	PF00069	0.591
MOD_GSK3_1	6	13	PF00069	0.538
MOD_GSK3_1	60	67	PF00069	0.548
MOD_GSK3_1	72	79	PF00069	0.722
MOD_N-GLC_1	106	111	PF02516	0.812
MOD_N-GLC_1	284	289	PF02516	0.573
MOD_N-GLC_1	79	84	PF02516	0.723
MOD_NEK2_1	101	106	PF00069	0.765
MOD_NEK2_1	138	143	PF00069	0.566
MOD_NEK2_1	146	151	PF00069	0.522
MOD_NEK2_1	305	310	PF00069	0.627
MOD_NEK2_1	60	65	PF00069	0.675
MOD_PIKK_1	118	124	PF00454	0.584
MOD_PIKK_1	168	174	PF00454	0.624
MOD_PIKK_1	268	274	PF00454	0.798
MOD_PIKK_1	321	327	PF00454	0.619
MOD_PIKK_1	87	93	PF00454	0.830
MOD_PKA_1	15	21	PF00069	0.562
MOD_PKA_1	44	50	PF00069	0.699
MOD_PKA_2	188	194	PF00069	0.632
MOD_PKA_2	28	34	PF00069	0.744
MOD_PKA_2	297	303	PF00069	0.801
MOD_PKA_2	44	50	PF00069	0.654
MOD_PKA_2	87	93	PF00069	0.830
MOD_PKB_1	185	193	PF00069	0.723
MOD_Plk_1	106	112	PF00069	0.561
MOD_Plk_1	147	153	PF00069	0.771
MOD_Plk_1	218	224	PF00069	0.807
MOD_Plk_1	253	259	PF00069	0.576
MOD_Plk_1	284	290	PF00069	0.573
MOD_Plk_1	79	85	PF00069	0.726
MOD_Plk_2-3	218	224	PF00069	0.807
MOD_Plk_2-3	286	292	PF00069	0.576
MOD_Plk_4	15	21	PF00069	0.802
MOD_Plk_4	301	307	PF00069	0.702
MOD_Plk_4	64	70	PF00069	0.777
MOD_ProDKin_1	246	252	PF00069	0.636
MOD_ProDKin_1	31	37	PF00069	0.742
MOD_ProDKin_1	350	356	PF00069	0.739
MOD_ProDKin_1	6	12	PF00069	0.688
MOD_ProDKin_1	92	98	PF00069	0.605
TRG_ENDOCYTIC_2	222	225	PF00928	0.565
TRG_ER_diArg_1	184	187	PF00400	0.705
TRG_ER_diArg_1	314	317	PF00400	0.599
TRG_NLS_MonoExtN_4	42	48	PF00514	0.606

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IAB5	Leptomonas seymouri	46%	100%
A0A3S7X7Y4	Leishmania donovani	67%	100%
A4IAM0	Leishmania infantum	68%	100%
E9B524	Leishmania mexicana (strain MHOM/GT/2001/U1103)	66%	100%
Q4Q2W2	Leishmania major	66%	99%