Endo/exonuclease/phosphatase domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Endonuclease/Exonuclease/phosphatase family, putative

Species:

Leishmania braziliensis

UniProt:

A4HAT4_LEIBR

TriTrypDb:

LbrM.20.1720 , LBRM2903_200027800

Length:

845

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HAT4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HAT4

Function

Biological processes
Term	Name	Level	Count
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	6	1
GO:0000956	nuclear-transcribed mRNA catabolic process	7	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006401	RNA catabolic process	5	1
GO:0006402	mRNA catabolic process	6	1
GO:0006417	regulation of translation	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009056	catabolic process	2	1
GO:0009057	macromolecule catabolic process	4	1
GO:0009889	regulation of biosynthetic process	4	1
GO:0009890	negative regulation of biosynthetic process	5	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0009893	positive regulation of metabolic process	4	1
GO:0009894	regulation of catabolic process	4	1
GO:0009896	positive regulation of catabolic process	5	1
GO:0009987	cellular process	1	1
GO:0010468	regulation of gene expression	5	1
GO:0010556	regulation of macromolecule biosynthetic process	5	1
GO:0010558	negative regulation of macromolecule biosynthetic process	6	1
GO:0010604	positive regulation of macromolecule metabolic process	5	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0010608	post-transcriptional regulation of gene expression	6	1
GO:0010629	negative regulation of gene expression	6	1
GO:0016070	RNA metabolic process	5	1
GO:0016071	mRNA metabolic process	6	1
GO:0017148	negative regulation of translation	7	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0019439	aromatic compound catabolic process	4	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031324	negative regulation of cellular metabolic process	5	1
GO:0031325	positive regulation of cellular metabolic process	5	1
GO:0031326	regulation of cellular biosynthetic process	5	1
GO:0031327	negative regulation of cellular biosynthetic process	6	1
GO:0031329	regulation of cellular catabolic process	5	1
GO:0031331	positive regulation of cellular catabolic process	6	1
GO:0034248	regulation of amide metabolic process	5	1
GO:0034249	negative regulation of amide metabolic process	6	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034655	nucleobase-containing compound catabolic process	4	1
GO:0043170	macromolecule metabolic process	3	1
GO:0043487	regulation of RNA stability	3	1
GO:0043488	regulation of mRNA stability	4	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044248	cellular catabolic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044265	obsolete cellular macromolecule catabolic process	4	1
GO:0044270	cellular nitrogen compound catabolic process	4	1
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	6	1
GO:0046483	heterocycle metabolic process	3	1
GO:0046700	heterocycle catabolic process	4	1
GO:0048518	positive regulation of biological process	3	1
GO:0048519	negative regulation of biological process	3	1
GO:0048522	positive regulation of cellular process	4	1
GO:0048523	negative regulation of cellular process	4	1
GO:0050779	RNA destabilization	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051172	negative regulation of nitrogen compound metabolic process	5	1
GO:0051173	positive regulation of nitrogen compound metabolic process	5	1
GO:0051246	regulation of protein metabolic process	5	1
GO:0051248	negative regulation of protein metabolic process	6	1
GO:0051252	regulation of RNA metabolic process	5	1
GO:0051254	positive regulation of RNA metabolic process	6	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0061013	regulation of mRNA catabolic process	6	1
GO:0061014	positive regulation of mRNA catabolic process	7	1
GO:0061157	mRNA destabilization	5	1
GO:0065007	biological regulation	1	1
GO:0065008	regulation of biological quality	2	1
GO:0071704	organic substance metabolic process	2	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1901361	organic cyclic compound catabolic process	4	1
GO:1901575	organic substance catabolic process	3	1
GO:1903311	regulation of mRNA metabolic process	6	1
GO:1903313	positive regulation of mRNA metabolic process	7	1
GO:2000112	obsolete regulation of cellular macromolecule biosynthetic process	6	1
GO:2000113	obsolete negative regulation of cellular macromolecule biosynthetic process	7	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	12
GO:0000175	3'-5'-RNA exonuclease activity	7	1
GO:0004518	nuclease activity	4	2
GO:0004527	exonuclease activity	5	2
GO:0004532	RNA exonuclease activity	5	1
GO:0004540	RNA nuclease activity	4	1
GO:0008408	3'-5' exonuclease activity	6	1
GO:0016787	hydrolase activity	2	2
GO:0016788	hydrolase activity, acting on ester bonds	3	2
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	1
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	6	1
GO:0140098	catalytic activity, acting on RNA	3	1
GO:0140640	catalytic activity, acting on a nucleic acid	2	1
GO:0004519	endonuclease activity	5	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	356	360	PF00656	0.382
CLV_MEL_PAP_1	547	553	PF00089	0.340
CLV_NRD_NRD_1	461	463	PF00675	0.340
CLV_NRD_NRD_1	707	709	PF00675	0.416
CLV_NRD_NRD_1	8	10	PF00675	0.533
CLV_NRD_NRD_1	87	89	PF00675	0.554
CLV_PCSK_KEX2_1	181	183	PF00082	0.748
CLV_PCSK_KEX2_1	221	223	PF00082	0.563
CLV_PCSK_KEX2_1	8	10	PF00082	0.533
CLV_PCSK_KEX2_1	87	89	PF00082	0.554
CLV_PCSK_PC1ET2_1	181	183	PF00082	0.748
CLV_PCSK_PC1ET2_1	221	223	PF00082	0.552
CLV_PCSK_PC7_1	217	223	PF00082	0.447
CLV_PCSK_PC7_1	4	10	PF00082	0.489
CLV_PCSK_SKI1_1	125	129	PF00082	0.651
CLV_PCSK_SKI1_1	207	211	PF00082	0.522
CLV_PCSK_SKI1_1	221	225	PF00082	0.550
CLV_PCSK_SKI1_1	427	431	PF00082	0.298
CLV_PCSK_SKI1_1	485	489	PF00082	0.346
CLV_PCSK_SKI1_1	558	562	PF00082	0.283
CLV_PCSK_SKI1_1	570	574	PF00082	0.316
CLV_PCSK_SKI1_1	656	660	PF00082	0.280
CLV_PCSK_SKI1_1	754	758	PF00082	0.349
CLV_Separin_Metazoa	806	810	PF03568	0.421
DEG_APCC_DBOX_1	124	132	PF00400	0.423
DEG_COP1_1	113	122	PF00400	0.483
DEG_Nend_Nbox_1	1	3	PF02207	0.567
DEG_SIAH_1	119	127	PF03145	0.445
DEG_SPOP_SBC_1	112	116	PF00917	0.687
DEG_SPOP_SBC_1	166	170	PF00917	0.512
DOC_CYCLIN_yCln2_LP_2	615	618	PF00134	0.197
DOC_MAPK_gen_1	181	188	PF00069	0.444
DOC_MAPK_HePTP_8	198	210	PF00069	0.363
DOC_MAPK_MEF2A_6	201	210	PF00069	0.467
DOC_MAPK_MEF2A_6	380	388	PF00069	0.494
DOC_PP1_RVXF_1	205	211	PF00149	0.493
DOC_PP1_RVXF_1	672	678	PF00149	0.399
DOC_PP2B_LxvP_1	209	212	PF13499	0.577
DOC_PP2B_LxvP_1	254	257	PF13499	0.534
DOC_PP2B_LxvP_1	407	410	PF13499	0.574
DOC_PP2B_LxvP_1	615	618	PF13499	0.197
DOC_PP2B_LxvP_1	780	783	PF13499	0.458
DOC_PP4_FxxP_1	210	213	PF00568	0.602
DOC_PP4_FxxP_1	823	826	PF00568	0.421
DOC_USP7_MATH_1	112	116	PF00917	0.670
DOC_USP7_MATH_1	12	16	PF00917	0.552
DOC_USP7_MATH_1	143	147	PF00917	0.524
DOC_USP7_MATH_1	166	170	PF00917	0.542
DOC_USP7_MATH_1	19	23	PF00917	0.572
DOC_USP7_MATH_1	213	217	PF00917	0.609
DOC_USP7_MATH_1	25	29	PF00917	0.552
DOC_USP7_MATH_1	250	254	PF00917	0.381
DOC_USP7_MATH_1	326	330	PF00917	0.400
DOC_USP7_MATH_1	348	352	PF00917	0.523
DOC_USP7_MATH_1	450	454	PF00917	0.300
DOC_USP7_MATH_1	624	628	PF00917	0.421
DOC_USP7_MATH_1	66	70	PF00917	0.572
DOC_USP7_MATH_1	92	96	PF00917	0.735
DOC_USP7_UBL2_3	221	225	PF12436	0.645
DOC_USP7_UBL2_3	55	59	PF12436	0.597
DOC_WW_Pin1_4	310	315	PF00397	0.541
DOC_WW_Pin1_4	351	356	PF00397	0.597
DOC_WW_Pin1_4	369	374	PF00397	0.373
DOC_WW_Pin1_4	41	46	PF00397	0.649
DOC_WW_Pin1_4	61	66	PF00397	0.514
DOC_WW_Pin1_4	622	627	PF00397	0.298
DOC_WW_Pin1_4	707	712	PF00397	0.456
DOC_WW_Pin1_4	714	719	PF00397	0.444
LIG_14-3-3_CanoR_1	182	187	PF00244	0.669
LIG_14-3-3_CanoR_1	240	247	PF00244	0.498
LIG_14-3-3_CanoR_1	385	389	PF00244	0.487
LIG_14-3-3_CanoR_1	427	432	PF00244	0.302
LIG_14-3-3_CanoR_1	656	663	PF00244	0.421
LIG_Actin_WH2_2	544	560	PF00022	0.337
LIG_APCC_ABBA_1	139	144	PF00400	0.536
LIG_APCC_ABBAyCdc20_2	225	231	PF00400	0.519
LIG_BRCT_BRCA1_1	328	332	PF00533	0.481
LIG_BRCT_BRCA1_1	540	544	PF00533	0.391
LIG_BRCT_BRCA1_1	626	630	PF00533	0.365
LIG_BRCT_BRCA1_1	66	70	PF00533	0.585
LIG_FHA_1	148	154	PF00498	0.466
LIG_FHA_1	183	189	PF00498	0.586
LIG_FHA_1	359	365	PF00498	0.396
LIG_FHA_1	372	378	PF00498	0.418
LIG_FHA_1	428	434	PF00498	0.295
LIG_FHA_1	658	664	PF00498	0.398
LIG_FHA_1	724	730	PF00498	0.249
LIG_FHA_1	808	814	PF00498	0.287
LIG_FHA_2	354	360	PF00498	0.391
LIG_FHA_2	415	421	PF00498	0.448
LIG_FHA_2	574	580	PF00498	0.231
LIG_FHA_2	788	794	PF00498	0.319
LIG_LIR_Apic_2	821	826	PF02991	0.419
LIG_LIR_Gen_1	270	281	PF02991	0.564
LIG_LIR_Gen_1	341	350	PF02991	0.435
LIG_LIR_Gen_1	392	403	PF02991	0.411
LIG_LIR_Gen_1	430	438	PF02991	0.280
LIG_LIR_Gen_1	522	533	PF02991	0.343
LIG_LIR_Gen_1	781	791	PF02991	0.389
LIG_LIR_Gen_1	796	805	PF02991	0.236
LIG_LIR_Nem_3	270	276	PF02991	0.480
LIG_LIR_Nem_3	341	345	PF02991	0.393
LIG_LIR_Nem_3	359	365	PF02991	0.506
LIG_LIR_Nem_3	420	426	PF02991	0.383
LIG_LIR_Nem_3	430	434	PF02991	0.296
LIG_LIR_Nem_3	486	491	PF02991	0.341
LIG_LIR_Nem_3	522	528	PF02991	0.343
LIG_LIR_Nem_3	541	547	PF02991	0.486
LIG_LIR_Nem_3	652	658	PF02991	0.299
LIG_LIR_Nem_3	781	787	PF02991	0.308
LIG_LIR_Nem_3	788	794	PF02991	0.295
LIG_LIR_Nem_3	796	800	PF02991	0.287
LIG_NRBOX	690	696	PF00104	0.414
LIG_Pex14_2	488	492	PF04695	0.410
LIG_Pex14_2	787	791	PF04695	0.421
LIG_PTB_Apo_2	279	286	PF02174	0.359
LIG_PTB_Apo_2	824	831	PF02174	0.295
LIG_PTB_Phospho_1	824	830	PF10480	0.295
LIG_SH2_CRK	303	307	PF00017	0.428
LIG_SH2_CRK	431	435	PF00017	0.280
LIG_SH2_CRK	501	505	PF00017	0.374
LIG_SH2_CRK	604	608	PF00017	0.295
LIG_SH2_CRK	655	659	PF00017	0.295
LIG_SH2_NCK_1	303	307	PF00017	0.416
LIG_SH2_PTP2	318	321	PF00017	0.361
LIG_SH2_STAP1	340	344	PF00017	0.293
LIG_SH2_STAT3	765	768	PF00017	0.365
LIG_SH2_STAT5	273	276	PF00017	0.488
LIG_SH2_STAT5	318	321	PF00017	0.328
LIG_SH2_STAT5	491	494	PF00017	0.344
LIG_SH2_STAT5	505	508	PF00017	0.218
LIG_SH2_STAT5	797	800	PF00017	0.327
LIG_SH3_1	809	815	PF00018	0.225
LIG_SH3_2	177	182	PF14604	0.636
LIG_SH3_2	212	217	PF14604	0.432
LIG_SH3_3	120	126	PF00018	0.617
LIG_SH3_3	137	143	PF00018	0.444
LIG_SH3_3	174	180	PF00018	0.763
LIG_SH3_3	209	215	PF00018	0.544
LIG_SH3_3	275	281	PF00018	0.403
LIG_SH3_3	311	317	PF00018	0.366
LIG_SH3_3	418	424	PF00018	0.336
LIG_SH3_3	620	626	PF00018	0.385
LIG_SH3_3	633	639	PF00018	0.414
LIG_SH3_3	808	814	PF00018	0.296
LIG_SH3_4	55	62	PF00018	0.522
LIG_SUMO_SIM_anti_2	327	332	PF11976	0.448
LIG_SUMO_SIM_anti_2	801	810	PF11976	0.302
LIG_SUMO_SIM_anti_2	832	840	PF11976	0.322
LIG_SUMO_SIM_par_1	146	152	PF11976	0.473
LIG_SUMO_SIM_par_1	184	190	PF11976	0.413
LIG_SUMO_SIM_par_1	453	460	PF11976	0.285
LIG_TRAF2_1	192	195	PF00917	0.583
LIG_TYR_ITIM	316	321	PF00017	0.466
LIG_TYR_ITIM	429	434	PF00017	0.295
LIG_UBA3_1	127	135	PF00899	0.423
LIG_WRPW_2	10	13	PF00400	0.499
LIG_WW_3	211	215	PF00397	0.632
MOD_CK1_1	108	114	PF00069	0.744
MOD_CK1_1	167	173	PF00069	0.641
MOD_CK1_1	24	30	PF00069	0.557
MOD_CK1_1	310	316	PF00069	0.558
MOD_CK1_1	346	352	PF00069	0.458
MOD_CK1_1	441	447	PF00069	0.318
MOD_CK1_1	562	568	PF00069	0.382
MOD_CK1_1	58	64	PF00069	0.792
MOD_CK1_1	625	631	PF00069	0.378
MOD_CK1_1	69	75	PF00069	0.700
MOD_CK1_1	737	743	PF00069	0.389
MOD_CK1_1	801	807	PF00069	0.380
MOD_CK1_1	97	103	PF00069	0.704
MOD_CK2_1	263	269	PF00069	0.507
MOD_CK2_1	508	514	PF00069	0.424
MOD_CK2_1	575	581	PF00069	0.315
MOD_CK2_1	714	720	PF00069	0.419
MOD_CK2_1	787	793	PF00069	0.321
MOD_GlcNHglycan	110	113	PF01048	0.689
MOD_GlcNHglycan	120	123	PF01048	0.669
MOD_GlcNHglycan	23	26	PF01048	0.568
MOD_GlcNHglycan	260	263	PF01048	0.563
MOD_GlcNHglycan	27	30	PF01048	0.566
MOD_GlcNHglycan	347	351	PF01048	0.563
MOD_GlcNHglycan	508	511	PF01048	0.353
MOD_GlcNHglycan	529	532	PF01048	0.197
MOD_GlcNHglycan	66	69	PF01048	0.651
MOD_GlcNHglycan	744	748	PF01048	0.368
MOD_GlcNHglycan	94	97	PF01048	0.800
MOD_GSK3_1	100	107	PF00069	0.747
MOD_GSK3_1	108	115	PF00069	0.722
MOD_GSK3_1	13	20	PF00069	0.599
MOD_GSK3_1	143	150	PF00069	0.491
MOD_GSK3_1	151	158	PF00069	0.460
MOD_GSK3_1	165	172	PF00069	0.671
MOD_GSK3_1	21	28	PF00069	0.587
MOD_GSK3_1	213	220	PF00069	0.706
MOD_GSK3_1	263	270	PF00069	0.635
MOD_GSK3_1	306	313	PF00069	0.510
MOD_GSK3_1	349	356	PF00069	0.442
MOD_GSK3_1	36	43	PF00069	0.647
MOD_GSK3_1	367	374	PF00069	0.533
MOD_GSK3_1	389	396	PF00069	0.425
MOD_GSK3_1	437	444	PF00069	0.386
MOD_GSK3_1	47	54	PF00069	0.573
MOD_GSK3_1	55	62	PF00069	0.494
MOD_GSK3_1	559	566	PF00069	0.390
MOD_GSK3_1	622	629	PF00069	0.398
MOD_GSK3_1	69	76	PF00069	0.775
MOD_GSK3_1	714	721	PF00069	0.397
MOD_GSK3_1	778	785	PF00069	0.438
MOD_GSK3_1	87	94	PF00069	0.660
MOD_N-GLC_1	217	222	PF02516	0.454
MOD_N-GLC_1	294	299	PF02516	0.522
MOD_N-GLC_1	37	42	PF02516	0.521
MOD_N-GLC_1	506	511	PF02516	0.374
MOD_N-GLC_1	646	651	PF02516	0.280
MOD_N-GLC_1	737	742	PF02516	0.491
MOD_N-GLC_1	785	790	PF02516	0.315
MOD_N-GLC_2	594	596	PF02516	0.280
MOD_NEK2_1	13	18	PF00069	0.617
MOD_NEK2_1	151	156	PF00069	0.400
MOD_NEK2_1	267	272	PF00069	0.499
MOD_NEK2_1	438	443	PF00069	0.329
MOD_NEK2_1	51	56	PF00069	0.594
MOD_NEK2_1	520	525	PF00069	0.376
MOD_NEK2_1	527	532	PF00069	0.313
MOD_NEK2_1	573	578	PF00069	0.477
MOD_NEK2_1	646	651	PF00069	0.313
MOD_NEK2_1	657	662	PF00069	0.295
MOD_NEK2_1	787	792	PF00069	0.400
MOD_NEK2_2	358	363	PF00069	0.346
MOD_PIKK_1	100	106	PF00454	0.517
MOD_PIKK_1	143	149	PF00454	0.563
MOD_PIKK_1	17	23	PF00454	0.505
MOD_PIKK_1	175	181	PF00454	0.499
MOD_PIKK_1	44	50	PF00454	0.514
MOD_PIKK_1	709	715	PF00454	0.252
MOD_PIKK_1	737	743	PF00454	0.441
MOD_PIKK_1	87	93	PF00454	0.580
MOD_PK_1	508	514	PF00069	0.421
MOD_PKA_1	181	187	PF00069	0.707
MOD_PKA_1	221	227	PF00069	0.508
MOD_PKA_1	87	93	PF00069	0.557
MOD_PKA_2	181	187	PF00069	0.684
MOD_PKA_2	213	219	PF00069	0.627
MOD_PKA_2	221	227	PF00069	0.559
MOD_PKA_2	239	245	PF00069	0.533
MOD_PKA_2	384	390	PF00069	0.483
MOD_PKA_2	520	526	PF00069	0.341
MOD_PKA_2	573	579	PF00069	0.458
MOD_PKA_2	87	93	PF00069	0.764
MOD_Plk_1	151	157	PF00069	0.507
MOD_Plk_1	250	256	PF00069	0.370
MOD_Plk_1	326	332	PF00069	0.457
MOD_Plk_1	358	364	PF00069	0.361
MOD_Plk_1	611	617	PF00069	0.488
MOD_Plk_1	778	784	PF00069	0.357
MOD_Plk_1	785	791	PF00069	0.298
MOD_Plk_1	801	807	PF00069	0.315
MOD_Plk_2-3	575	581	PF00069	0.300
MOD_Plk_4	182	188	PF00069	0.544
MOD_Plk_4	280	286	PF00069	0.359
MOD_Plk_4	326	332	PF00069	0.389
MOD_Plk_4	539	545	PF00069	0.461
MOD_Plk_4	611	617	PF00069	0.407
MOD_Plk_4	66	72	PF00069	0.684
MOD_ProDKin_1	310	316	PF00069	0.538
MOD_ProDKin_1	351	357	PF00069	0.600
MOD_ProDKin_1	369	375	PF00069	0.377
MOD_ProDKin_1	41	47	PF00069	0.647
MOD_ProDKin_1	61	67	PF00069	0.513
MOD_ProDKin_1	622	628	PF00069	0.298
MOD_ProDKin_1	707	713	PF00069	0.456
MOD_ProDKin_1	714	720	PF00069	0.444
MOD_SUMO_rev_2	190	198	PF00179	0.499
TRG_DiLeu_BaEn_2	513	519	PF01217	0.421
TRG_DiLeu_BaLyEn_6	123	128	PF01217	0.508
TRG_DiLeu_BaLyEn_6	204	209	PF01217	0.481
TRG_DiLeu_BaLyEn_6	653	658	PF01217	0.421
TRG_DiLeu_BaLyEn_6	679	684	PF01217	0.374
TRG_ENDOCYTIC_2	273	276	PF00928	0.488
TRG_ENDOCYTIC_2	318	321	PF00928	0.381
TRG_ENDOCYTIC_2	423	426	PF00928	0.386
TRG_ENDOCYTIC_2	431	434	PF00928	0.280
TRG_ENDOCYTIC_2	435	438	PF00928	0.285
TRG_ENDOCYTIC_2	501	504	PF00928	0.374
TRG_ENDOCYTIC_2	604	607	PF00928	0.295
TRG_ENDOCYTIC_2	655	658	PF00928	0.280
TRG_ENDOCYTIC_2	797	800	PF00928	0.295
TRG_ER_diArg_1	205	208	PF00400	0.456
TRG_ER_diArg_1	7	9	PF00400	0.528
TRG_NES_CRM1_1	803	816	PF08389	0.365
TRG_Pf-PMV_PEXEL_1	125	129	PF00026	0.433
TRG_Pf-PMV_PEXEL_1	682	687	PF00026	0.421

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IC26	Leptomonas seymouri	62%	100%
A0A0S4J452	Bodo saltans	33%	100%
A0A1X0PAG3	Trypanosomatidae	44%	100%
A0A3R7LBT2	Trypanosoma rangeli	42%	100%
A0A3S7X813	Leishmania donovani	80%	100%
A4I9Z4	Leishmania infantum	76%	100%
C9ZMN4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
E9B508	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%
Q4Q2X8	Leishmania major	80%	99%
V5DGT6	Trypanosoma cruzi	42%	100%