Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

eukaryotic translation initiation factor 2-alpha kinase 2

Species:

Leishmania braziliensis

UniProt:

A4HAS7_LEIBR

TriTrypDb:

LbrM.20.1650 , LBRM2903_200027100

Length:

1467

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005768	endosome	7	1
GO:0005829	cytosol	2	1
GO:0016020	membrane	2	3
GO:0031090	organelle membrane	3	1
GO:0031410	cytoplasmic vesicle	6	1
GO:0031982	vesicle	4	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0097708	intracellular vesicle	5	1
GO:0110165	cellular anatomical entity	1	3
GO:1990578	perinuclear endoplasmic reticulum membrane	4	1

Expansion

Sequence features

A4HAS7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	7
GO:0006793	phosphorus metabolic process	3	7
GO:0006796	phosphate-containing compound metabolic process	4	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0016310	phosphorylation	5	7
GO:0019538	protein metabolic process	3	7
GO:0036211	protein modification process	4	7
GO:0043170	macromolecule metabolic process	3	7
GO:0043412	macromolecule modification	4	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0071704	organic substance metabolic process	2	7
GO:1901564	organonitrogen compound metabolic process	3	7
GO:0001932	regulation of protein phosphorylation	7	1
GO:0006417	regulation of translation	6	1
GO:0006446	regulation of translational initiation	7	1
GO:0009889	regulation of biosynthetic process	4	1
GO:0010468	regulation of gene expression	5	1
GO:0010556	regulation of macromolecule biosynthetic process	5	1
GO:0010608	post-transcriptional regulation of gene expression	6	1
GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	6	1
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	5	1
GO:0019220	regulation of phosphate metabolic process	6	1
GO:0019222	regulation of metabolic process	3	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031326	regulation of cellular biosynthetic process	5	1
GO:0031399	regulation of protein modification process	6	1
GO:0034248	regulation of amide metabolic process	5	1
GO:0042325	regulation of phosphorylation	7	1
GO:0043555	regulation of translation in response to stress	7	1
GO:0043558	regulation of translational initiation in response to stress	8	1
GO:0048583	regulation of response to stimulus	3	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051174	regulation of phosphorus metabolic process	5	1
GO:0051246	regulation of protein metabolic process	5	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0080134	regulation of response to stress	4	1
GO:0080135	regulation of cellular response to stress	4	1
GO:2000112	obsolete regulation of cellular macromolecule biosynthetic process	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003824	catalytic activity	1	7
GO:0004672	protein kinase activity	3	7
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0016301	kinase activity	4	7
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	7
GO:0017076	purine nucleotide binding	4	7
GO:0030554	adenyl nucleotide binding	5	7
GO:0032553	ribonucleotide binding	3	7
GO:0032555	purine ribonucleotide binding	4	7
GO:0032559	adenyl ribonucleotide binding	5	7
GO:0035639	purine ribonucleoside triphosphate binding	4	7
GO:0036094	small molecule binding	2	7
GO:0043167	ion binding	2	7
GO:0043168	anion binding	3	7
GO:0097159	organic cyclic compound binding	2	7
GO:0097367	carbohydrate derivative binding	2	7
GO:0140096	catalytic activity, acting on a protein	2	7
GO:1901265	nucleoside phosphate binding	3	7
GO:1901363	heterocyclic compound binding	2	7
GO:0004674	protein serine/threonine kinase activity	4	1
GO:0004683	calmodulin-dependent protein kinase activity	5	1
GO:0004686	elongation factor-2 kinase activity	6	1
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	2	1
GO:0020037	heme binding	4	1
GO:0045182	translation regulator activity	1	4
GO:0046906	tetrapyrrole binding	3	1
GO:0003676	nucleic acid binding	3	3
GO:0003743	translation initiation factor activity	4	3
GO:0008135	translation factor activity, RNA binding	3	3
GO:0090079	translation regulator activity, nucleic acid binding	2	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	995	999	PF00656	0.548
CLV_NRD_NRD_1	1047	1049	PF00675	0.260
CLV_NRD_NRD_1	1103	1105	PF00675	0.346
CLV_NRD_NRD_1	1212	1214	PF00675	0.349
CLV_NRD_NRD_1	1397	1399	PF00675	0.679
CLV_NRD_NRD_1	1455	1457	PF00675	0.575
CLV_NRD_NRD_1	199	201	PF00675	0.558
CLV_NRD_NRD_1	25	27	PF00675	0.534
CLV_NRD_NRD_1	582	584	PF00675	0.519
CLV_PCSK_KEX2_1	1046	1048	PF00082	0.238
CLV_PCSK_KEX2_1	1102	1104	PF00082	0.346
CLV_PCSK_KEX2_1	1389	1391	PF00082	0.691
CLV_PCSK_KEX2_1	1397	1399	PF00082	0.650
CLV_PCSK_KEX2_1	1455	1457	PF00082	0.657
CLV_PCSK_KEX2_1	199	201	PF00082	0.558
CLV_PCSK_KEX2_1	24	26	PF00082	0.535
CLV_PCSK_KEX2_1	357	359	PF00082	0.785
CLV_PCSK_KEX2_1	977	979	PF00082	0.238
CLV_PCSK_PC1ET2_1	1102	1104	PF00082	0.346
CLV_PCSK_PC1ET2_1	1389	1391	PF00082	0.750
CLV_PCSK_PC1ET2_1	357	359	PF00082	0.655
CLV_PCSK_PC1ET2_1	977	979	PF00082	0.238
CLV_PCSK_PC7_1	20	26	PF00082	0.531
CLV_PCSK_SKI1_1	1058	1062	PF00082	0.376
CLV_PCSK_SKI1_1	1078	1082	PF00082	0.183
CLV_PCSK_SKI1_1	1199	1203	PF00082	0.346
CLV_PCSK_SKI1_1	1213	1217	PF00082	0.346
CLV_PCSK_SKI1_1	341	345	PF00082	0.634
CLV_PCSK_SKI1_1	41	45	PF00082	0.415
CLV_PCSK_SKI1_1	816	820	PF00082	0.383
CLV_Separin_Metazoa	1055	1059	PF03568	0.619
CLV_Separin_Metazoa	742	746	PF03568	0.723
DEG_APCC_DBOX_1	1212	1220	PF00400	0.558
DEG_MDM2_SWIB_1	963	971	PF02201	0.546
DEG_Nend_UBRbox_3	1	3	PF02207	0.502
DEG_SCF_FBW7_1	166	172	PF00400	0.343
DEG_SPOP_SBC_1	417	421	PF00917	0.468
DEG_SPOP_SBC_1	437	441	PF00917	0.408
DEG_SPOP_SBC_1	62	66	PF00917	0.380
DEG_SPOP_SBC_1	795	799	PF00917	0.651
DOC_CDC14_PxL_1	460	468	PF14671	0.481
DOC_CDC14_PxL_1	518	526	PF14671	0.316
DOC_CKS1_1	1003	1008	PF01111	0.438
DOC_CKS1_1	166	171	PF01111	0.342
DOC_CYCLIN_RxL_1	974	985	PF00134	0.438
DOC_CYCLIN_yCln2_LP_2	143	149	PF00134	0.417
DOC_MAPK_gen_1	1078	1087	PF00069	0.460
DOC_MAPK_gen_1	1213	1224	PF00069	0.701
DOC_MAPK_gen_1	1329	1337	PF00069	0.591
DOC_MAPK_gen_1	199	205	PF00069	0.361
DOC_MAPK_gen_1	6	15	PF00069	0.497
DOC_MAPK_MEF2A_6	1217	1226	PF00069	0.707
DOC_MAPK_MEF2A_6	144	151	PF00069	0.409
DOC_MAPK_MEF2A_6	41	48	PF00069	0.548
DOC_MAPK_NFAT4_5	41	49	PF00069	0.619
DOC_PP1_RVXF_1	907	913	PF00149	0.546
DOC_PP2B_LxvP_1	1001	1004	PF13499	0.438
DOC_PP2B_LxvP_1	1181	1184	PF13499	0.619
DOC_PP2B_LxvP_1	1320	1323	PF13499	0.532
DOC_PP2B_LxvP_1	147	150	PF13499	0.403
DOC_PP4_FxxP_1	1321	1324	PF00568	0.693
DOC_PP4_FxxP_1	185	188	PF00568	0.276
DOC_PP4_FxxP_1	461	464	PF00568	0.401
DOC_PP4_FxxP_1	79	82	PF00568	0.291
DOC_USP7_MATH_1	1107	1111	PF00917	0.555
DOC_USP7_MATH_1	1247	1251	PF00917	0.595
DOC_USP7_MATH_1	1288	1292	PF00917	0.724
DOC_USP7_MATH_1	1356	1360	PF00917	0.496
DOC_USP7_MATH_1	169	173	PF00917	0.432
DOC_USP7_MATH_1	228	232	PF00917	0.390
DOC_USP7_MATH_1	417	421	PF00917	0.551
DOC_USP7_MATH_1	437	441	PF00917	0.494
DOC_USP7_MATH_1	492	496	PF00917	0.390
DOC_USP7_MATH_1	571	575	PF00917	0.324
DOC_USP7_MATH_1	608	612	PF00917	0.361
DOC_USP7_MATH_1	62	66	PF00917	0.458
DOC_USP7_MATH_1	722	726	PF00917	0.736
DOC_USP7_MATH_1	795	799	PF00917	0.787
DOC_USP7_MATH_1	825	829	PF00917	0.768
DOC_USP7_MATH_1	838	842	PF00917	0.613
DOC_USP7_MATH_1	94	98	PF00917	0.433
DOC_USP7_MATH_2	873	879	PF00917	0.629
DOC_USP7_UBL2_3	905	909	PF12436	0.546
DOC_WW_Pin1_4	1002	1007	PF00397	0.438
DOC_WW_Pin1_4	1128	1133	PF00397	0.546
DOC_WW_Pin1_4	1239	1244	PF00397	0.738
DOC_WW_Pin1_4	1281	1286	PF00397	0.769
DOC_WW_Pin1_4	1363	1368	PF00397	0.464
DOC_WW_Pin1_4	165	170	PF00397	0.377
DOC_WW_Pin1_4	245	250	PF00397	0.442
DOC_WW_Pin1_4	295	300	PF00397	0.477
DOC_WW_Pin1_4	304	309	PF00397	0.540
DOC_WW_Pin1_4	320	325	PF00397	0.549
DOC_WW_Pin1_4	364	369	PF00397	0.575
DOC_WW_Pin1_4	427	432	PF00397	0.468
DOC_WW_Pin1_4	51	56	PF00397	0.261
DOC_WW_Pin1_4	572	577	PF00397	0.392
DOC_WW_Pin1_4	58	63	PF00397	0.347
DOC_WW_Pin1_4	610	615	PF00397	0.331
DOC_WW_Pin1_4	692	697	PF00397	0.709
DOC_WW_Pin1_4	699	704	PF00397	0.639
DOC_WW_Pin1_4	752	757	PF00397	0.700
DOC_WW_Pin1_4	762	767	PF00397	0.612
DOC_WW_Pin1_4	810	815	PF00397	0.661
DOC_WW_Pin1_4	819	824	PF00397	0.756
DOC_WW_Pin1_4	869	874	PF00397	0.671
LIG_14-3-3_CanoR_1	1021	1027	PF00244	0.480
LIG_14-3-3_CanoR_1	1390	1395	PF00244	0.483
LIG_14-3-3_CanoR_1	1461	1466	PF00244	0.588
LIG_14-3-3_CanoR_1	154	159	PF00244	0.358
LIG_14-3-3_CanoR_1	199	204	PF00244	0.362
LIG_14-3-3_CanoR_1	235	240	PF00244	0.527
LIG_14-3-3_CanoR_1	334	343	PF00244	0.448
LIG_14-3-3_CanoR_1	371	378	PF00244	0.547
LIG_14-3-3_CanoR_1	383	392	PF00244	0.403
LIG_14-3-3_CanoR_1	498	508	PF00244	0.369
LIG_14-3-3_CanoR_1	600	609	PF00244	0.327
LIG_14-3-3_CanoR_1	682	690	PF00244	0.716
LIG_14-3-3_CanoR_1	9	13	PF00244	0.568
LIG_14-3-3_CanoR_1	90	94	PF00244	0.368
LIG_14-3-3_CanoR_1	924	932	PF00244	0.546
LIG_Actin_WH2_2	586	602	PF00022	0.291
LIG_AP2alpha_2	709	711	PF02296	0.510
LIG_BIR_III_4	123	127	PF00653	0.447
LIG_BRCT_BRCA1_1	1148	1152	PF00533	0.546
LIG_BRCT_BRCA1_1	235	239	PF00533	0.565
LIG_BRCT_BRCA1_1	646	650	PF00533	0.411
LIG_BRCT_BRCA1_1	96	100	PF00533	0.253
LIG_CSL_BTD_1	542	545	PF09270	0.383
LIG_deltaCOP1_diTrp_1	1043	1051	PF00928	0.546
LIG_deltaCOP1_diTrp_1	854	862	PF00928	0.712
LIG_FHA_1	1109	1115	PF00498	0.438
LIG_FHA_1	128	134	PF00498	0.496
LIG_FHA_1	1408	1414	PF00498	0.378
LIG_FHA_1	211	217	PF00498	0.373
LIG_FHA_1	372	378	PF00498	0.490
LIG_FHA_1	38	44	PF00498	0.472
LIG_FHA_1	417	423	PF00498	0.488
LIG_FHA_1	442	448	PF00498	0.504
LIG_FHA_1	48	54	PF00498	0.223
LIG_FHA_1	631	637	PF00498	0.273
LIG_FHA_1	713	719	PF00498	0.715
LIG_FHA_1	728	734	PF00498	0.680
LIG_FHA_1	763	769	PF00498	0.548
LIG_FHA_1	845	851	PF00498	0.728
LIG_FHA_1	889	895	PF00498	0.581
LIG_FHA_1	989	995	PF00498	0.505
LIG_FHA_2	1038	1044	PF00498	0.546
LIG_FHA_2	1138	1144	PF00498	0.526
LIG_FHA_2	1165	1171	PF00498	0.546
LIG_FHA_2	1355	1361	PF00498	0.395
LIG_FHA_2	1364	1370	PF00498	0.409
LIG_FHA_2	1404	1410	PF00498	0.377
LIG_FHA_2	1423	1429	PF00498	0.360
LIG_FHA_2	166	172	PF00498	0.426
LIG_FHA_2	365	371	PF00498	0.435
LIG_FHA_2	564	570	PF00498	0.419
LIG_FHA_2	75	81	PF00498	0.314
LIG_FHA_2	771	777	PF00498	0.704
LIG_FHA_2	874	880	PF00498	0.754
LIG_FHA_2	993	999	PF00498	0.551
LIG_LIR_Apic_2	1131	1137	PF02991	0.546
LIG_LIR_Apic_2	1319	1324	PF02991	0.659
LIG_LIR_Apic_2	1433	1438	PF02991	0.456
LIG_LIR_Apic_2	458	464	PF02991	0.391
LIG_LIR_Apic_2	566	571	PF02991	0.379
LIG_LIR_Apic_2	759	764	PF02991	0.703
LIG_LIR_Apic_2	76	82	PF02991	0.330
LIG_LIR_Gen_1	1025	1033	PF02991	0.514
LIG_LIR_Gen_1	1164	1172	PF02991	0.546
LIG_LIR_Gen_1	1313	1322	PF02991	0.567
LIG_LIR_Gen_1	157	167	PF02991	0.363
LIG_LIR_Gen_1	168	176	PF02991	0.393
LIG_LIR_Gen_1	271	281	PF02991	0.364
LIG_LIR_Gen_1	594	602	PF02991	0.426
LIG_LIR_Gen_1	638	645	PF02991	0.394
LIG_LIR_Nem_3	1025	1029	PF02991	0.538
LIG_LIR_Nem_3	11	15	PF02991	0.605
LIG_LIR_Nem_3	1164	1168	PF02991	0.585
LIG_LIR_Nem_3	1313	1317	PF02991	0.566
LIG_LIR_Nem_3	157	162	PF02991	0.356
LIG_LIR_Nem_3	271	277	PF02991	0.272
LIG_LIR_Nem_3	594	598	PF02991	0.423
LIG_LIR_Nem_3	638	642	PF02991	0.394
LIG_NRBOX	38	44	PF00104	0.506
LIG_OCRL_FandH_1	1313	1325	PF00620	0.505
LIG_Pex14_1	568	572	PF04695	0.290
LIG_Pex14_2	335	339	PF04695	0.525
LIG_Pex14_2	900	904	PF04695	0.599
LIG_Pex14_2	963	967	PF04695	0.507
LIG_PTB_Apo_2	1429	1436	PF02174	0.537
LIG_PTB_Phospho_1	1429	1435	PF10480	0.540
LIG_Rb_LxCxE_1	767	788	PF01857	0.564
LIG_Rb_pABgroove_1	338	346	PF01858	0.438
LIG_REV1ctd_RIR_1	1049	1057	PF16727	0.619
LIG_SH2_CRK	1026	1030	PF00017	0.516
LIG_SH2_CRK	1435	1439	PF00017	0.448
LIG_SH2_CRK	526	530	PF00017	0.294
LIG_SH2_CRK	595	599	PF00017	0.288
LIG_SH2_CRK	91	95	PF00017	0.438
LIG_SH2_NCK_1	1134	1138	PF00017	0.619
LIG_SH2_PTP2	451	454	PF00017	0.392
LIG_SH2_STAP1	118	122	PF00017	0.266
LIG_SH2_STAP1	286	290	PF00017	0.404
LIG_SH2_STAP1	595	599	PF00017	0.288
LIG_SH2_STAP1	930	934	PF00017	0.546
LIG_SH2_STAT3	1059	1062	PF00017	0.619
LIG_SH2_STAT3	561	564	PF00017	0.465
LIG_SH2_STAT5	1035	1038	PF00017	0.507
LIG_SH2_STAT5	1069	1072	PF00017	0.546
LIG_SH2_STAT5	1444	1447	PF00017	0.524
LIG_SH2_STAT5	167	170	PF00017	0.355
LIG_SH2_STAT5	189	192	PF00017	0.358
LIG_SH2_STAT5	211	214	PF00017	0.460
LIG_SH2_STAT5	391	394	PF00017	0.472
LIG_SH2_STAT5	451	454	PF00017	0.392
LIG_SH2_STAT5	91	94	PF00017	0.409
LIG_SH2_STAT5	964	967	PF00017	0.504
LIG_SH3_1	1435	1441	PF00018	0.450
LIG_SH3_1	754	760	PF00018	0.671
LIG_SH3_3	1142	1148	PF00018	0.546
LIG_SH3_3	1282	1288	PF00018	0.678
LIG_SH3_3	1428	1434	PF00018	0.453
LIG_SH3_3	1435	1441	PF00018	0.469
LIG_SH3_3	1460	1466	PF00018	0.584
LIG_SH3_3	299	305	PF00018	0.569
LIG_SH3_3	356	362	PF00018	0.457
LIG_SH3_3	570	576	PF00018	0.440
LIG_SH3_3	728	734	PF00018	0.769
LIG_SH3_3	754	760	PF00018	0.741
LIG_SUMO_SIM_par_1	1155	1160	PF11976	0.546
LIG_SUMO_SIM_par_1	1222	1228	PF11976	0.725
LIG_SUMO_SIM_par_1	127	132	PF11976	0.409
LIG_SUMO_SIM_par_1	49	54	PF11976	0.261
LIG_SUMO_SIM_par_1	841	851	PF11976	0.738
LIG_SxIP_EBH_1	154	168	PF03271	0.277
LIG_TRAF2_1	1231	1234	PF00917	0.770
LIG_TRAF2_1	1425	1428	PF00917	0.403
LIG_TRAF2_1	739	742	PF00917	0.759
LIG_TRAF2_1	773	776	PF00917	0.660
LIG_TRAF2_1	893	896	PF00917	0.639
LIG_TYR_ITIM	524	529	PF00017	0.291
LIG_TYR_ITIM	593	598	PF00017	0.287
LIG_UBA3_1	1215	1221	PF00899	0.626
LIG_UBA3_1	899	905	PF00899	0.600
LIG_WRC_WIRS_1	1162	1167	PF05994	0.585
LIG_WRC_WIRS_1	1311	1316	PF05994	0.504
LIG_WRC_WIRS_1	636	641	PF05994	0.411
LIG_WRC_WIRS_1	713	718	PF05994	0.647
LIG_WRC_WIRS_1	807	812	PF05994	0.553
LIG_WW_3	655	659	PF00397	0.597
LIG_WW_3	862	866	PF00397	0.558
MOD_CDK_SPK_2	320	325	PF00069	0.564
MOD_CDK_SPK_2	810	815	PF00069	0.554
MOD_CDK_SPxK_1	810	816	PF00069	0.663
MOD_CDK_SPxxK_3	364	371	PF00069	0.591
MOD_CK1_1	1228	1234	PF00069	0.580
MOD_CK1_1	1347	1353	PF00069	0.392
MOD_CK1_1	1378	1384	PF00069	0.471
MOD_CK1_1	138	144	PF00069	0.492
MOD_CK1_1	1403	1409	PF00069	0.407
MOD_CK1_1	157	163	PF00069	0.343
MOD_CK1_1	172	178	PF00069	0.405
MOD_CK1_1	241	247	PF00069	0.483
MOD_CK1_1	312	318	PF00069	0.587
MOD_CK1_1	320	326	PF00069	0.434
MOD_CK1_1	436	442	PF00069	0.528
MOD_CK1_1	610	616	PF00069	0.375
MOD_CK1_1	63	69	PF00069	0.512
MOD_CK1_1	676	682	PF00069	0.727
MOD_CK1_1	712	718	PF00069	0.672
MOD_CK1_1	736	742	PF00069	0.682
MOD_CK1_1	798	804	PF00069	0.595
MOD_CK1_1	83	89	PF00069	0.435
MOD_CK1_1	839	845	PF00069	0.673
MOD_CK1_1	882	888	PF00069	0.787
MOD_CK1_1	997	1003	PF00069	0.546
MOD_CK2_1	1132	1138	PF00069	0.619
MOD_CK2_1	1164	1170	PF00069	0.546
MOD_CK2_1	1228	1234	PF00069	0.710
MOD_CK2_1	1310	1316	PF00069	0.533
MOD_CK2_1	1354	1360	PF00069	0.406
MOD_CK2_1	1363	1369	PF00069	0.410
MOD_CK2_1	1403	1409	PF00069	0.456
MOD_CK2_1	1422	1428	PF00069	0.511
MOD_CK2_1	165	171	PF00069	0.424
MOD_CK2_1	258	264	PF00069	0.451
MOD_CK2_1	469	475	PF00069	0.507
MOD_CK2_1	563	569	PF00069	0.376
MOD_CK2_1	736	742	PF00069	0.763
MOD_CK2_1	770	776	PF00069	0.684
MOD_CK2_1	869	875	PF00069	0.649
MOD_GlcNHglycan	1007	1010	PF01048	0.376
MOD_GlcNHglycan	104	107	PF01048	0.583
MOD_GlcNHglycan	1249	1252	PF01048	0.365
MOD_GlcNHglycan	1295	1298	PF01048	0.543
MOD_GlcNHglycan	1307	1310	PF01048	0.430
MOD_GlcNHglycan	1380	1383	PF01048	0.642
MOD_GlcNHglycan	1400	1403	PF01048	0.682
MOD_GlcNHglycan	1414	1417	PF01048	0.595
MOD_GlcNHglycan	1422	1425	PF01048	0.701
MOD_GlcNHglycan	1463	1466	PF01048	0.798
MOD_GlcNHglycan	31	34	PF01048	0.454
MOD_GlcNHglycan	313	317	PF01048	0.792
MOD_GlcNHglycan	435	438	PF01048	0.716
MOD_GlcNHglycan	454	457	PF01048	0.604
MOD_GlcNHglycan	469	472	PF01048	0.635
MOD_GlcNHglycan	620	623	PF01048	0.567
MOD_GlcNHglycan	684	687	PF01048	0.466
MOD_GlcNHglycan	800	803	PF01048	0.496
MOD_GlcNHglycan	82	85	PF01048	0.604
MOD_GlcNHglycan	827	830	PF01048	0.589
MOD_GSK3_1	1108	1115	PF00069	0.441
MOD_GSK3_1	1128	1135	PF00069	0.547
MOD_GSK3_1	1146	1153	PF00069	0.470
MOD_GSK3_1	1271	1278	PF00069	0.725
MOD_GSK3_1	1288	1295	PF00069	0.702
MOD_GSK3_1	1343	1350	PF00069	0.535
MOD_GSK3_1	1378	1385	PF00069	0.537
MOD_GSK3_1	1403	1410	PF00069	0.416
MOD_GSK3_1	1418	1425	PF00069	0.506
MOD_GSK3_1	165	172	PF00069	0.386
MOD_GSK3_1	235	242	PF00069	0.480
MOD_GSK3_1	284	291	PF00069	0.400
MOD_GSK3_1	300	307	PF00069	0.519
MOD_GSK3_1	348	355	PF00069	0.418
MOD_GSK3_1	412	419	PF00069	0.455
MOD_GSK3_1	423	430	PF00069	0.524
MOD_GSK3_1	433	440	PF00069	0.563
MOD_GSK3_1	465	472	PF00069	0.450
MOD_GSK3_1	47	54	PF00069	0.443
MOD_GSK3_1	481	488	PF00069	0.396
MOD_GSK3_1	56	63	PF00069	0.548
MOD_GSK3_1	673	680	PF00069	0.743
MOD_GSK3_1	722	729	PF00069	0.729
MOD_GSK3_1	752	759	PF00069	0.739
MOD_GSK3_1	785	792	PF00069	0.660
MOD_GSK3_1	794	801	PF00069	0.678
MOD_GSK3_1	806	813	PF00069	0.643
MOD_GSK3_1	819	826	PF00069	0.755
MOD_GSK3_1	836	843	PF00069	0.619
MOD_GSK3_1	869	876	PF00069	0.742
MOD_GSK3_1	880	887	PF00069	0.819
MOD_GSK3_1	89	96	PF00069	0.324
MOD_GSK3_1	988	995	PF00069	0.548
MOD_LATS_1	1396	1402	PF00433	0.559
MOD_N-GLC_1	192	197	PF02516	0.554
MOD_N-GLC_1	242	247	PF02516	0.714
MOD_N-GLC_1	352	357	PF02516	0.651
MOD_N-GLC_1	401	406	PF02516	0.640
MOD_N-GLC_1	441	446	PF02516	0.652
MOD_N-GLC_1	486	491	PF02516	0.617
MOD_N-GLC_1	726	731	PF02516	0.384
MOD_N-GLC_1	839	844	PF02516	0.563
MOD_N-GLC_2	1254	1256	PF02516	0.348
MOD_NEK2_1	100	105	PF00069	0.367
MOD_NEK2_1	1161	1166	PF00069	0.546
MOD_NEK2_1	1197	1202	PF00069	0.580
MOD_NEK2_1	1310	1315	PF00069	0.528
MOD_NEK2_1	192	197	PF00069	0.354
MOD_NEK2_1	221	226	PF00069	0.508
MOD_NEK2_1	239	244	PF00069	0.486
MOD_NEK2_1	268	273	PF00069	0.277
MOD_NEK2_1	381	386	PF00069	0.497
MOD_NEK2_1	401	406	PF00069	0.322
MOD_NEK2_1	46	51	PF00069	0.442
MOD_NEK2_1	499	504	PF00069	0.366
MOD_NEK2_1	535	540	PF00069	0.369
MOD_NEK2_1	618	623	PF00069	0.487
MOD_NEK2_1	644	649	PF00069	0.411
MOD_NEK2_1	805	810	PF00069	0.667
MOD_NEK2_1	89	94	PF00069	0.371
MOD_NEK2_2	635	640	PF00069	0.411
MOD_NEK2_2	914	919	PF00069	0.619
MOD_PIKK_1	1225	1231	PF00454	0.562
MOD_PIKK_1	233	239	PF00454	0.564
MOD_PIKK_1	290	296	PF00454	0.439
MOD_PIKK_1	300	306	PF00454	0.531
MOD_PIKK_1	334	340	PF00454	0.526
MOD_PIKK_1	383	389	PF00454	0.450
MOD_PIKK_1	56	62	PF00454	0.669
MOD_PIKK_1	884	890	PF00454	0.806
MOD_PKA_1	199	205	PF00069	0.364
MOD_PKA_2	1037	1043	PF00069	0.524
MOD_PKA_2	1271	1277	PF00069	0.743
MOD_PKA_2	199	205	PF00069	0.364
MOD_PKA_2	370	376	PF00069	0.554
MOD_PKA_2	497	503	PF00069	0.366
MOD_PKA_2	536	542	PF00069	0.358
MOD_PKA_2	673	679	PF00069	0.728
MOD_PKA_2	8	14	PF00069	0.536
MOD_PKA_2	879	885	PF00069	0.795
MOD_PKA_2	89	95	PF00069	0.370
MOD_PKA_2	923	929	PF00069	0.546
MOD_Plk_1	1123	1129	PF00069	0.526
MOD_Plk_1	1344	1350	PF00069	0.528
MOD_Plk_1	1448	1454	PF00069	0.459
MOD_Plk_1	1459	1465	PF00069	0.504
MOD_Plk_1	15	21	PF00069	0.674
MOD_Plk_1	192	198	PF00069	0.354
MOD_Plk_1	284	290	PF00069	0.395
MOD_Plk_1	348	354	PF00069	0.392
MOD_Plk_1	401	407	PF00069	0.442
MOD_Plk_1	413	419	PF00069	0.456
MOD_Plk_1	593	599	PF00069	0.294
MOD_Plk_1	726	732	PF00069	0.690
MOD_Plk_1	736	742	PF00069	0.756
MOD_Plk_1	74	80	PF00069	0.421
MOD_Plk_1	844	850	PF00069	0.732
MOD_Plk_1	873	879	PF00069	0.737
MOD_Plk_1	997	1003	PF00069	0.525
MOD_Plk_2-3	709	715	PF00069	0.697
MOD_Plk_2-3	844	850	PF00069	0.659
MOD_Plk_4	1197	1203	PF00069	0.619
MOD_Plk_4	1260	1266	PF00069	0.540
MOD_Plk_4	1310	1316	PF00069	0.533
MOD_Plk_4	1347	1353	PF00069	0.365
MOD_Plk_4	1375	1381	PF00069	0.451
MOD_Plk_4	1383	1389	PF00069	0.488
MOD_Plk_4	1449	1455	PF00069	0.494
MOD_Plk_4	154	160	PF00069	0.358
MOD_Plk_4	193	199	PF00069	0.354
MOD_Plk_4	443	449	PF00069	0.436
MOD_Plk_4	469	475	PF00069	0.491
MOD_Plk_4	563	569	PF00069	0.449
MOD_Plk_4	594	600	PF00069	0.299
MOD_Plk_4	74	80	PF00069	0.324
MOD_Plk_4	914	920	PF00069	0.546
MOD_ProDKin_1	1002	1008	PF00069	0.438
MOD_ProDKin_1	1128	1134	PF00069	0.546
MOD_ProDKin_1	1239	1245	PF00069	0.734
MOD_ProDKin_1	1281	1287	PF00069	0.769
MOD_ProDKin_1	1363	1369	PF00069	0.463
MOD_ProDKin_1	165	171	PF00069	0.378
MOD_ProDKin_1	245	251	PF00069	0.446
MOD_ProDKin_1	295	301	PF00069	0.483
MOD_ProDKin_1	304	310	PF00069	0.539
MOD_ProDKin_1	320	326	PF00069	0.546
MOD_ProDKin_1	364	370	PF00069	0.571
MOD_ProDKin_1	427	433	PF00069	0.470
MOD_ProDKin_1	51	57	PF00069	0.261
MOD_ProDKin_1	572	578	PF00069	0.395
MOD_ProDKin_1	58	64	PF00069	0.349
MOD_ProDKin_1	610	616	PF00069	0.330
MOD_ProDKin_1	692	698	PF00069	0.706
MOD_ProDKin_1	699	705	PF00069	0.636
MOD_ProDKin_1	752	758	PF00069	0.701
MOD_ProDKin_1	762	768	PF00069	0.613
MOD_ProDKin_1	810	816	PF00069	0.663
MOD_ProDKin_1	819	825	PF00069	0.757
MOD_ProDKin_1	869	875	PF00069	0.673
MOD_SUMO_rev_2	1074	1083	PF00179	0.546
MOD_SUMO_rev_2	603	608	PF00179	0.311
MOD_SUMO_rev_2	895	900	PF00179	0.638
TRG_DiLeu_BaEn_3	775	781	PF01217	0.662
TRG_DiLeu_BaLyEn_6	38	43	PF01217	0.444
TRG_DiLeu_BaLyEn_6	611	616	PF01217	0.358
TRG_DiLeu_LyEn_5	264	269	PF01217	0.491
TRG_ENDOCYTIC_2	1026	1029	PF00928	0.516
TRG_ENDOCYTIC_2	167	170	PF00928	0.384
TRG_ENDOCYTIC_2	189	192	PF00928	0.358
TRG_ENDOCYTIC_2	274	277	PF00928	0.360
TRG_ENDOCYTIC_2	451	454	PF00928	0.392
TRG_ENDOCYTIC_2	526	529	PF00928	0.293
TRG_ENDOCYTIC_2	595	598	PF00928	0.288
TRG_ER_diArg_1	1045	1048	PF00400	0.546
TRG_ER_diArg_1	1397	1399	PF00400	0.481
TRG_ER_diArg_1	1454	1456	PF00400	0.370
TRG_ER_diArg_1	198	200	PF00400	0.355
TRG_ER_diArg_1	24	26	PF00400	0.729
TRG_ER_diArg_1	864	867	PF00400	0.569
TRG_Pf-PMV_PEXEL_1	1213	1218	PF00026	0.349
TRG_Pf-PMV_PEXEL_1	1456	1460	PF00026	0.660
TRG_Pf-PMV_PEXEL_1	409	413	PF00026	0.645

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8U7	Leptomonas seymouri	47%	99%
A0A3S5H7W8	Leishmania donovani	71%	100%
A4I9Y7	Leishmania infantum	71%	100%
E9B501	Leishmania mexicana (strain MHOM/GT/2001/U1103)	69%	100%
Q4Q2Y5	Leishmania major	71%	100%