Ribosome maturation protein SDO1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Shwachman-Bodian-Diamond syndrome (SBDS) protein/SBDS protein C-terminal domain containing protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HAM9_LEIBR

TriTrypDb:

LbrM.20.1140 , LBRM2903_200019900

Length:

530

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HAM9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HAM9

Function

Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	7
GO:0022613	ribonucleoprotein complex biogenesis	4	7
GO:0042254	ribosome biogenesis	5	7
GO:0044085	cellular component biogenesis	3	7
GO:0071840	cellular component organization or biogenesis	2	7

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	213	217	PF00656	0.493
CLV_C14_Caspase3-7	363	367	PF00656	0.729
CLV_C14_Caspase3-7	431	435	PF00656	0.576
CLV_C14_Caspase3-7	481	485	PF00656	0.535
CLV_NRD_NRD_1	12	14	PF00675	0.516
CLV_NRD_NRD_1	292	294	PF00675	0.753
CLV_NRD_NRD_1	339	341	PF00675	0.659
CLV_NRD_NRD_1	354	356	PF00675	0.632
CLV_NRD_NRD_1	453	455	PF00675	0.574
CLV_NRD_NRD_1	492	494	PF00675	0.589
CLV_PCSK_FUR_1	352	356	PF00082	0.565
CLV_PCSK_KEX2_1	12	14	PF00082	0.516
CLV_PCSK_KEX2_1	292	294	PF00082	0.832
CLV_PCSK_KEX2_1	339	341	PF00082	0.703
CLV_PCSK_KEX2_1	354	356	PF00082	0.544
CLV_PCSK_KEX2_1	415	417	PF00082	0.650
CLV_PCSK_KEX2_1	455	457	PF00082	0.556
CLV_PCSK_PC1ET2_1	415	417	PF00082	0.650
CLV_PCSK_PC1ET2_1	455	457	PF00082	0.556
CLV_PCSK_SKI1_1	155	159	PF00082	0.290
CLV_PCSK_SKI1_1	292	296	PF00082	0.559
CLV_PCSK_SKI1_1	461	465	PF00082	0.752
CLV_PCSK_SKI1_1	88	92	PF00082	0.300
DEG_SCF_TRCP1_1	366	372	PF00400	0.545
DOC_CYCLIN_yClb5_NLxxxL_5	227	236	PF00134	0.518
DOC_MAPK_gen_1	12	19	PF00069	0.476
DOC_MAPK_gen_1	154	160	PF00069	0.486
DOC_MAPK_gen_1	21	31	PF00069	0.486
DOC_MAPK_MEF2A_6	24	31	PF00069	0.493
DOC_MAPK_MEF2A_6	310	317	PF00069	0.532
DOC_MAPK_MEF2A_6	374	383	PF00069	0.533
DOC_USP7_MATH_1	130	134	PF00917	0.462
DOC_USP7_MATH_1	139	143	PF00917	0.517
DOC_USP7_MATH_1	212	216	PF00917	0.499
DOC_USP7_MATH_1	245	249	PF00917	0.572
DOC_USP7_MATH_1	286	290	PF00917	0.628
DOC_USP7_MATH_1	296	300	PF00917	0.663
DOC_USP7_UBL2_3	24	28	PF12436	0.539
DOC_USP7_UBL2_3	415	419	PF12436	0.605
DOC_USP7_UBL2_3	457	461	PF12436	0.756
DOC_USP7_UBL2_3	464	468	PF12436	0.665
DOC_USP7_UBL2_3	494	498	PF12436	0.624
LIG_14-3-3_CanoR_1	180	189	PF00244	0.535
LIG_14-3-3_CanoR_1	292	301	PF00244	0.552
LIG_Actin_WH2_2	128	143	PF00022	0.418
LIG_BIR_II_1	1	5	PF00653	0.664
LIG_BRCT_BRCA1_1	394	398	PF00533	0.550
LIG_deltaCOP1_diTrp_1	511	517	PF00928	0.717
LIG_FHA_1	102	108	PF00498	0.584
LIG_FHA_1	248	254	PF00498	0.376
LIG_FHA_1	295	301	PF00498	0.547
LIG_FHA_1	376	382	PF00498	0.574
LIG_FHA_1	422	428	PF00498	0.573
LIG_FHA_2	181	187	PF00498	0.559
LIG_FHA_2	479	485	PF00498	0.543
LIG_FHA_2	80	86	PF00498	0.560
LIG_LIR_Gen_1	56	67	PF02991	0.486
LIG_LIR_Nem_3	108	114	PF02991	0.400
LIG_LIR_Nem_3	56	62	PF02991	0.486
LIG_NRBOX	159	165	PF00104	0.560
LIG_NRBOX	262	268	PF00104	0.472
LIG_SH2_STAT5	66	69	PF00017	0.560
LIG_SUMO_SIM_anti_2	113	119	PF11976	0.486
LIG_SUMO_SIM_anti_2	15	21	PF11976	0.328
LIG_SUMO_SIM_anti_2	223	229	PF11976	0.327
LIG_SUMO_SIM_anti_2	311	317	PF11976	0.532
LIG_TRAF2_1	485	488	PF00917	0.702
LIG_TRAF2_1	99	102	PF00917	0.487
LIG_UBA3_1	232	241	PF00899	0.431
MOD_CK1_1	210	216	PF00069	0.493
MOD_CK1_1	246	252	PF00069	0.553
MOD_CK1_1	299	305	PF00069	0.676
MOD_CK1_1	40	46	PF00069	0.560
MOD_CK1_1	471	477	PF00069	0.556
MOD_CK2_1	180	186	PF00069	0.557
MOD_CK2_1	328	334	PF00069	0.757
MOD_CK2_1	40	46	PF00069	0.587
MOD_CK2_1	471	477	PF00069	0.665
MOD_CK2_1	482	488	PF00069	0.599
MOD_CK2_1	66	72	PF00069	0.487
MOD_CK2_1	79	85	PF00069	0.486
MOD_Cter_Amidation	337	340	PF01082	0.697
MOD_Cter_Amidation	352	355	PF01082	0.541
MOD_Cter_Amidation	413	416	PF01082	0.680
MOD_Cter_Amidation	465	468	PF01082	0.650
MOD_GlcNHglycan	1	4	PF01048	0.680
MOD_GlcNHglycan	212	215	PF01048	0.644
MOD_GlcNHglycan	245	248	PF01048	0.593
MOD_GlcNHglycan	288	291	PF01048	0.621
MOD_GlcNHglycan	301	304	PF01048	0.694
MOD_GlcNHglycan	306	309	PF01048	0.629
MOD_GlcNHglycan	366	369	PF01048	0.600
MOD_GlcNHglycan	370	374	PF01048	0.607
MOD_GlcNHglycan	42	45	PF01048	0.375
MOD_GlcNHglycan	421	424	PF01048	0.766
MOD_GlcNHglycan	470	473	PF01048	0.558
MOD_GSK3_1	206	213	PF00069	0.601
MOD_GSK3_1	243	250	PF00069	0.386
MOD_GSK3_1	282	289	PF00069	0.677
MOD_GSK3_1	292	299	PF00069	0.623
MOD_GSK3_1	304	311	PF00069	0.591
MOD_GSK3_1	478	485	PF00069	0.545
MOD_N-GLC_1	210	215	PF02516	0.579
MOD_N-GLC_1	322	327	PF02516	0.725
MOD_N-GLC_1	419	424	PF02516	0.767
MOD_NEK2_1	164	169	PF00069	0.482
MOD_NEK2_1	364	369	PF00069	0.632
MOD_PIKK_1	116	122	PF00454	0.483
MOD_PIKK_1	124	130	PF00454	0.491
MOD_PIKK_1	428	434	PF00454	0.748
MOD_PIKK_1	7	13	PF00454	0.519
MOD_PKA_1	12	18	PF00069	0.487
MOD_PKA_1	292	298	PF00069	0.559
MOD_PKA_1	456	462	PF00069	0.551
MOD_PKA_2	12	18	PF00069	0.497
MOD_PKA_2	179	185	PF00069	0.526
MOD_PKA_2	20	26	PF00069	0.486
MOD_PKA_2	292	298	PF00069	0.553
MOD_PKB_1	454	462	PF00069	0.551
MOD_Plk_1	311	317	PF00069	0.555
MOD_Plk_1	478	484	PF00069	0.552
MOD_Plk_4	156	162	PF00069	0.469
MOD_Plk_4	220	226	PF00069	0.375
MOD_Plk_4	311	317	PF00069	0.532
MOD_Plk_4	72	78	PF00069	0.479
MOD_SUMO_for_1	240	243	PF00179	0.392
MOD_SUMO_for_1	27	30	PF00179	0.539
MOD_SUMO_rev_2	262	272	PF00179	0.465
TRG_ER_diArg_1	352	355	PF00400	0.570
TRG_NES_CRM1_1	138	150	PF08389	0.486
TRG_NES_CRM1_1	382	393	PF08389	0.614
TRG_NLS_Bipartite_1	437	459	PF00514	0.540
TRG_NLS_MonoCore_2	454	459	PF00514	0.552
TRG_NLS_MonoExtC_3	414	419	PF00514	0.568
TRG_NLS_MonoExtC_3	455	460	PF00514	0.746
TRG_NLS_MonoExtC_3	463	468	PF00514	0.662
TRG_NLS_MonoExtN_4	413	419	PF00514	0.669
TRG_NLS_MonoExtN_4	454	461	PF00514	0.746

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IFC9	Leishmania donovani	71%	99%
A0A422NGQ3	Trypanosoma rangeli	51%	100%
A4I9S1	Leishmania infantum	72%	99%
E9B4T2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	72%	99%
Q4Q394	Leishmania major	73%	100%