Serine/threonine-protein phosphatase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

serine/threonine-protein phosphatase PP1, putative

Species:

Leishmania braziliensis

UniProt:

A4HAI9_LEIBR

TriTrypDb:

LbrM.20.0730 , LBRM2903_200014200

Length:

301

Annotations

LeishMANIAdb annotations

A large collection of various protein phosphatases. Very highly expanded in kinetoplastids.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 6
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 60

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 28

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 25
NetGPI	no	yes: 0, no: 25

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	4
GO:0005737	cytoplasm	2	4
GO:0043226	organelle	2	4
GO:0043227	membrane-bounded organelle	3	4
GO:0043229	intracellular organelle	3	4
GO:0043231	intracellular membrane-bounded organelle	4	4
GO:0110165	cellular anatomical entity	1	4

Expansion

Sequence features

A4HAI9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HAI9

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	26
GO:0004721	phosphoprotein phosphatase activity	3	26
GO:0004722	protein serine/threonine phosphatase activity	4	26
GO:0005488	binding	1	24
GO:0016787	hydrolase activity	2	26
GO:0016788	hydrolase activity, acting on ester bonds	3	26
GO:0016791	phosphatase activity	5	26
GO:0017018	myosin phosphatase activity	5	26
GO:0042578	phosphoric ester hydrolase activity	4	26
GO:0043167	ion binding	2	24
GO:0043169	cation binding	3	24
GO:0046872	metal ion binding	4	24
GO:0140096	catalytic activity, acting on a protein	2	26

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	143	145	PF00675	0.362
CLV_PCSK_KEX2_1	142	144	PF00082	0.362
CLV_PCSK_PC1ET2_1	142	144	PF00082	0.362
CLV_PCSK_SKI1_1	148	152	PF00082	0.365
CLV_PCSK_SKI1_1	16	20	PF00082	0.317
CLV_PCSK_SKI1_1	199	203	PF00082	0.375
CLV_PCSK_SKI1_1	27	31	PF00082	0.307
CLV_PCSK_SKI1_1	37	41	PF00082	0.325
CLV_PCSK_SKI1_1	44	48	PF00082	0.328
DEG_APCC_DBOX_1	198	206	PF00400	0.519
DEG_APCC_DBOX_1	36	44	PF00400	0.533
DOC_MAPK_gen_1	142	149	PF00069	0.362
DOC_MAPK_gen_1	21	31	PF00069	0.571
DOC_PP2B_LxvP_1	295	298	PF13499	0.440
DOC_PP4_FxxP_1	268	271	PF00568	0.374
DOC_WW_Pin1_4	175	180	PF00397	0.362
LIG_14-3-3_CanoR_1	222	227	PF00244	0.361
LIG_14-3-3_CanoR_1	262	268	PF00244	0.531
LIG_14-3-3_CanoR_1	37	47	PF00244	0.583
LIG_14-3-3_CanoR_1	97	103	PF00244	0.352
LIG_AP2alpha_1	153	157	PF02296	0.362
LIG_BIR_II_1	1	5	PF00653	0.686
LIG_BRCT_BRCA1_1	224	228	PF00533	0.361
LIG_EH1_1	99	107	PF00400	0.454
LIG_FHA_1	157	163	PF00498	0.362
LIG_FHA_2	10	16	PF00498	0.587
LIG_LIR_Apic_2	204	210	PF02991	0.362
LIG_LIR_Apic_2	266	271	PF02991	0.372
LIG_LIR_Gen_1	154	165	PF02991	0.362
LIG_LIR_Gen_1	235	244	PF02991	0.363
LIG_LIR_Gen_1	293	299	PF02991	0.424
LIG_LIR_Gen_1	86	95	PF02991	0.362
LIG_LIR_Nem_3	117	122	PF02991	0.362
LIG_LIR_Nem_3	253	259	PF02991	0.370
LIG_LIR_Nem_3	293	297	PF02991	0.417
LIG_LIR_Nem_3	4	10	PF02991	0.371
LIG_LIR_Nem_3	86	91	PF02991	0.362
LIG_NRBOX	201	207	PF00104	0.362
LIG_PCNA_yPIPBox_3	11	24	PF02747	0.520
LIG_Pex14_2	153	157	PF04695	0.362
LIG_PTB_Apo_2	84	91	PF02174	0.379
LIG_REV1ctd_RIR_1	117	127	PF16727	0.362
LIG_REV1ctd_RIR_1	256	266	PF16727	0.400
LIG_SH2_CRK	111	115	PF00017	0.362
LIG_SH2_CRK	71	75	PF00017	0.398
LIG_SH2_GRB2like	85	88	PF00017	0.379
LIG_SH2_STAP1	85	89	PF00017	0.379
LIG_SH2_STAT5	109	112	PF00017	0.362
LIG_SH2_STAT5	226	229	PF00017	0.361
LIG_SH2_STAT5	273	276	PF00017	0.454
LIG_SH2_STAT5	88	91	PF00017	0.362
LIG_SH2_STAT5	94	97	PF00017	0.362
LIG_SUMO_SIM_anti_2	103	109	PF11976	0.247
LIG_SUMO_SIM_par_1	263	269	PF11976	0.373
LIG_UBA3_1	105	112	PF00899	0.375
LIG_UBA3_1	13	21	PF00899	0.462
LIG_UBA3_1	73	79	PF00899	0.398
MOD_CK1_1	183	189	PF00069	0.417
MOD_CK2_1	9	15	PF00069	0.388
MOD_GlcNHglycan	268	271	PF01048	0.375
MOD_GSK3_1	175	182	PF00069	0.357
MOD_N-GLC_2	272	274	PF02516	0.424
MOD_NEK2_1	1	6	PF00069	0.596
MOD_NEK2_1	258	263	PF00069	0.475
MOD_NEK2_1	290	295	PF00069	0.418
MOD_NEK2_1	9	14	PF00069	0.358
MOD_PIKK_1	46	52	PF00454	0.523
MOD_Plk_1	179	185	PF00069	0.358
MOD_Plk_4	183	189	PF00069	0.400
MOD_Plk_4	222	228	PF00069	0.361
MOD_Plk_4	263	269	PF00069	0.373
MOD_Plk_4	290	296	PF00069	0.430
MOD_Plk_4	9	15	PF00069	0.379
MOD_ProDKin_1	175	181	PF00069	0.362
MOD_SUMO_for_1	31	34	PF00179	0.550
TRG_DiLeu_BaEn_1	103	108	PF01217	0.295
TRG_DiLeu_BaEn_1	117	122	PF01217	0.449
TRG_ENDOCYTIC_2	111	114	PF00928	0.362
TRG_ENDOCYTIC_2	135	138	PF00928	0.362
TRG_ENDOCYTIC_2	256	259	PF00928	0.405
TRG_ENDOCYTIC_2	70	73	PF00928	0.377
TRG_ENDOCYTIC_2	88	91	PF00928	0.289
TRG_ER_diArg_1	143	145	PF00400	0.362
TRG_NES_CRM1_1	180	191	PF08389	0.400
TRG_NES_CRM1_1	230	243	PF08389	0.361

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7S7	Leptomonas seymouri	57%	100%
A0A0N1HSR2	Leptomonas seymouri	43%	81%
A0A0N1I0V3	Leptomonas seymouri	55%	77%
A0A0N1IBK9	Leptomonas seymouri	43%	98%
A0A0N1ILH2	Leptomonas seymouri	30%	71%
A0A0N1P9X9	Leptomonas seymouri	40%	98%
A0A0N1PAV9	Leptomonas seymouri	59%	83%
A0A0N1PCC5	Leptomonas seymouri	38%	97%
A0A0N1PDK9	Leptomonas seymouri	41%	95%
A0A0S4IIW0	Bodo saltans	30%	76%
A0A0S4ILF8	Bodo saltans	43%	99%
A0A0S4J1J1	Bodo saltans	33%	78%
A0A0S4JDD1	Bodo saltans	36%	67%
A0A0S4JJ52	Bodo saltans	61%	79%
A0A0S4JJ96	Bodo saltans	49%	96%
A0A0S4JJH3	Bodo saltans	88%	96%
A0A0S4KGD7	Bodo saltans	42%	100%
A0A0S4KKU2	Bodo saltans	40%	98%
A0A0S4KM73	Bodo saltans	47%	76%
A0A1X0NK88	Trypanosomatidae	60%	87%
A0A1X0NNN6	Trypanosomatidae	42%	90%
A0A1X0NS37	Trypanosomatidae	38%	100%
A0A1X0NS65	Trypanosomatidae	42%	99%
A0A1X0NUA6	Trypanosomatidae	39%	75%
A0A1X0NYR5	Trypanosomatidae	58%	99%
A0A1X0P6J3	Trypanosomatidae	35%	79%
A0A1X0P7H9	Trypanosomatidae	36%	67%
A0A1X0P7Q5	Trypanosomatidae	31%	78%
A0A1X0P982	Trypanosomatidae	55%	91%
A0A1X0P9R6	Trypanosomatidae	30%	66%
A0A1X0PA67	Trypanosomatidae	87%	100%
A0A1X0PAK9	Trypanosomatidae	89%	100%
A0A1X0PBJ2	Trypanosomatidae	34%	98%
A0A3Q8I8M6	Leishmania donovani	30%	70%
A0A3Q8IFB2	Leishmania donovani	94%	100%
A0A3Q8IH18	Leishmania donovani	44%	98%
A0A3Q8IHY7	Leishmania donovani	91%	100%
A0A3R7KQR6	Trypanosoma rangeli	42%	89%
A0A3R7M399	Trypanosoma rangeli	31%	69%
A0A3R7MBA3	Trypanosoma rangeli	36%	67%
A0A3R7MFZ7	Trypanosoma rangeli	54%	91%
A0A3R7MM48	Trypanosoma rangeli	39%	75%
A0A3R7N275	Trypanosoma rangeli	58%	99%
A0A3R7NP99	Trypanosoma rangeli	34%	98%
A0A3S5H6K2	Leishmania donovani	23%	71%
A0A3S5H6T9	Leishmania donovani	42%	80%
A0A3S5H7Q6	Leishmania donovani	60%	82%
A0A3S7WZ39	Leishmania donovani	41%	95%
A0A3S7X190	Leishmania donovani	57%	100%
A0A3S7X1Y0	Leishmania donovani	40%	98%
A0A3S7X7I6	Leishmania donovani	96%	100%
A0A3S7X7J8	Leishmania donovani	55%	100%
A0A3S7X7K2	Leishmania donovani	89%	99%
A0A3S7X8K6	Leishmania donovani	38%	97%
A0A3S7XAY3	Leishmania donovani	29%	74%
A0A422N8P1	Trypanosoma rangeli	88%	100%
A0A422N9D5	Trypanosoma rangeli	31%	76%
A0A422NKG0	Trypanosoma rangeli	39%	98%
A0A422NPG1	Trypanosoma rangeli	60%	86%
A0A422NYN7	Trypanosoma rangeli	41%	99%
A0A422P483	Trypanosoma rangeli	33%	71%
A0C1E4	Paramecium tetraurelia	43%	99%
A0CCD2	Paramecium tetraurelia	43%	98%
A0CNL9	Paramecium tetraurelia	42%	96%
A0DJ90	Paramecium tetraurelia	38%	99%
A2X2G3	Oryza sativa subsp. indica	44%	98%
A2XN40	Oryza sativa subsp. indica	41%	98%
A2YEB4	Oryza sativa subsp. indica	43%	98%
A3C4N5	Oryza sativa subsp. japonica	41%	96%
A4H7Z3	Leishmania braziliensis	44%	100%
A4HAI7	Leishmania braziliensis	94%	100%
A4HAI8	Leishmania braziliensis	88%	100%
A4HAJ8	Leishmania braziliensis	54%	100%
A4HBE2	Leishmania braziliensis	37%	97%
A4HE75	Leishmania braziliensis	40%	100%
A4HGA9	Leishmania braziliensis	57%	100%
A4HGX0	Leishmania braziliensis	43%	100%
A4HJQ1	Leishmania braziliensis	61%	100%
A4HKU9	Leishmania braziliensis	44%	98%
A4HP65	Leishmania braziliensis	27%	75%
A4HV49	Leishmania infantum	23%	71%
A4HVT0	Leishmania infantum	31%	70%
A4HWC1	Leishmania infantum	42%	80%
A4I1H6	Leishmania infantum	41%	95%
A4I3E3	Leishmania infantum	57%	100%
A4I400	Leishmania infantum	40%	98%
A4I768	Leishmania infantum	61%	82%
A4I8C8	Leishmania infantum	44%	98%
A4I9P2	Leishmania infantum	55%	100%
A4IAJ0	Leishmania infantum	38%	97%
A4IDH0	Leishmania infantum	29%	74%
A6H772	Bos taurus	42%	98%
A8WGP3	Danio rerio	42%	97%
A8XE00	Caenorhabditis briggsae	42%	90%
A9JRC7	Danio rerio	42%	98%
C9ZJZ6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	93%
C9ZM48	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	71%
C9ZMF3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	87%
C9ZN02	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	54%	92%
C9ZN04	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	100%
C9ZN06	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	84%	100%
C9ZWN3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	87%
C9ZX13	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	70%
D0A358	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	77%
D0A805	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	99%
D0A970	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	98%
D0AAU4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	99%
E9AHS8	Leishmania infantum	88%	100%
E9AHS9	Leishmania infantum	88%	99%
E9AHT0	Leishmania infantum	94%	100%
E9AHT1	Leishmania infantum	96%	100%
E9APH5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	70%
E9AQ21	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	80%
E9ASX3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	74%
E9AXL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	95%
E9AZN0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	57%	100%
E9B090	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	98%
E9B262	Leishmania mexicana (strain MHOM/GT/2001/U1103)	61%	82%
E9B387	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	98%
E9B4P8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
E9B4P9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	97%
E9B4Q0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E9B4Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
E9B4Q6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	55%	100%
E9B5L4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	97%
G5EGK8	Caenorhabditis elegans	43%	95%
O00743	Homo sapiens	40%	99%
O02658	Caenorhabditis elegans	51%	99%
O04856	Nicotiana tabacum	61%	95%
O04857	Nicotiana tabacum	59%	97%
O04858	Nicotiana tabacum	57%	99%
O04860	Nicotiana tabacum	39%	96%
O04951	Arabidopsis thaliana	42%	98%
O15757	Dictyostelium discoideum	60%	94%
O74789	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	86%
O76932	Drosophila melanogaster	41%	98%
O82733	Arabidopsis thaliana	57%	91%
O82734	Arabidopsis thaliana	56%	93%
P0C5D7	Oryza sativa subsp. indica	41%	96%
P11084	Oryctolagus cuniculus	42%	98%
P11493	Sus scrofa	44%	100%
P11611	Oryctolagus cuniculus	44%	97%
P11612	Drosophila melanogaster	55%	96%
P12982	Drosophila melanogaster	61%	100%
P13681	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	61%	92%
P20604	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	97%
P20654	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	61%	93%
P22198	Zea mays	57%	95%
P23594	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	41%	82%
P23595	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	42%	80%
P23635	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	42%	97%
P23636	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	42%	93%
P23696	Drosophila melanogaster	44%	97%
P23733	Trypanosoma brucei brucei	55%	87%
P23734	Trypanosoma brucei brucei	55%	87%
P23777	Brassica napus	59%	100%
P23778	Brassica napus	41%	97%
P23880	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	61%	93%
P30366	Arabidopsis thaliana	59%	95%
P32345	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	44%	98%
P32598	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	61%	96%
P32838	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	82%
P34350	Caenorhabditis elegans	31%	80%
P36614	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	41%	99%
P36873	Homo sapiens	61%	93%
P36874	Xenopus laevis	61%	93%
P48458	Caenorhabditis elegans	47%	83%
P48459	Caenorhabditis elegans	43%	66%
P48460	Caenorhabditis elegans	40%	66%
P48461	Drosophila melanogaster	61%	92%
P48462	Drosophila melanogaster	61%	91%
P48463	Gallus gallus	44%	97%
P48480	Acetabularia peniculus	62%	94%
P48481	Acetabularia peniculus	62%	94%
P48482	Arabidopsis thaliana	64%	96%
P48483	Arabidopsis thaliana	59%	93%
P48484	Arabidopsis thaliana	58%	94%
P48485	Arabidopsis thaliana	61%	96%
P48486	Arabidopsis thaliana	60%	93%
P48487	Brassica oleracea	59%	95%
P48488	Medicago sativa subsp. varia	60%	94%
P48489	Oryza sativa subsp. japonica	62%	93%
P48490	Phaseolus vulgaris	57%	96%
P48528	Arabidopsis thaliana	40%	99%
P48529	Arabidopsis thaliana	40%	99%
P48577	Acetabularia peniculus	41%	98%
P48578	Arabidopsis thaliana	41%	96%
P48579	Helianthus annuus	44%	99%
P48580	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	41%	92%
P48726	Paramecium tetraurelia	40%	96%
P48727	Caenorhabditis elegans	61%	90%
P49576	Paramecium tetraurelia	38%	99%
P60510	Homo sapiens	42%	98%
P61287	Bos taurus	61%	93%
P61292	Sus scrofa	62%	92%
P62136	Homo sapiens	62%	91%
P62137	Mus musculus	62%	91%
P62138	Rattus norvegicus	62%	91%
P62139	Oryctolagus cuniculus	62%	91%
P62140	Homo sapiens	62%	92%
P62141	Mus musculus	62%	92%
P62142	Rattus norvegicus	62%	92%
P62143	Oryctolagus cuniculus	62%	92%
P62207	Gallus gallus	62%	92%
P62714	Homo sapiens	44%	97%
P62715	Mus musculus	44%	97%
P62716	Rattus norvegicus	44%	97%
P63087	Mus musculus	61%	93%
P63088	Rattus norvegicus	61%	93%
P63330	Mus musculus	42%	97%
P63331	Rattus norvegicus	42%	97%
P67774	Bos taurus	42%	97%
P67775	Homo sapiens	42%	97%
P67776	Sus scrofa	42%	97%
P67777	Oryctolagus cuniculus	42%	97%
P91420	Caenorhabditis elegans	50%	99%
P97470	Mus musculus	42%	98%
Q05547	Drosophila melanogaster	61%	100%
Q06009	Medicago sativa	40%	96%
Q07098	Arabidopsis thaliana	42%	98%
Q07099	Arabidopsis thaliana	42%	98%
Q07100	Arabidopsis thaliana	41%	96%
Q09496	Caenorhabditis elegans	40%	91%
Q0DBD3	Oryza sativa subsp. japonica	43%	98%
Q0E2S4	Oryza sativa subsp. japonica	44%	98%
Q0P594	Bos taurus	44%	97%
Q10298	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	42%	98%
Q10BT5	Oryza sativa subsp. japonica	41%	98%
Q27497	Caenorhabditis elegans	60%	91%
Q27884	Drosophila melanogaster	39%	99%
Q3SWW9	Bos taurus	62%	92%
Q3T0E7	Bos taurus	62%	91%
Q4Q1M5	Leishmania major	29%	100%
Q4Q2C2	Leishmania major	38%	100%
Q4Q3C0	Leishmania major	55%	100%
Q4Q3C5	Leishmania major	98%	100%
Q4Q3C6	Leishmania major	94%	100%
Q4Q3C7	Leishmania major	88%	100%
Q4Q3C8	Leishmania major	90%	99%
Q4Q4W8	Leishmania major	44%	100%
Q4Q5Z8	Leishmania major	61%	100%
Q4Q7Z5	Leishmania major	39%	100%
Q4Q8K1	Leishmania major	58%	100%
Q4Q9W1	Leishmania major	41%	100%
Q4QFG0	Leishmania major	43%	100%
Q4QG03	Leishmania major	30%	100%
Q4QGT8	Leishmania major	22%	100%
Q4WM22	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	42%	78%
Q54RD6	Dictyostelium discoideum	43%	96%
Q59KY8	Candida albicans (strain SC5314 / ATCC MYA-2876)	38%	96%
Q5A6B6	Candida albicans (strain SC5314 / ATCC MYA-2876)	40%	72%
Q5BJ92	Rattus norvegicus	42%	98%
Q5I085	Xenopus tropicalis	62%	92%
Q5R6K8	Pongo abelii	42%	98%
Q5R740	Pongo abelii	62%	92%
Q61JR3	Caenorhabditis briggsae	60%	91%
Q627N3	Caenorhabditis briggsae	61%	90%
Q64620	Rattus norvegicus	40%	99%
Q6BFF6	Paramecium tetraurelia	41%	96%
Q6CNT6	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	43%	98%
Q6FM81	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	42%	97%
Q6GQL2	Xenopus laevis	62%	92%
Q6IP91	Xenopus laevis	42%	98%
Q6NVU2	Xenopus tropicalis	61%	93%
Q6P861	Xenopus tropicalis	42%	98%
Q74ZR2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	43%	97%
Q7SZ10	Xenopus laevis	61%	93%
Q8LSN3	Pisum sativum	39%	99%
Q8MJ46	Canis lupus familiaris	61%	93%
Q8MJ47	Canis lupus familiaris	62%	92%
Q8WMS6	Canis lupus familiaris	62%	91%
Q8X178	Blumeria hordei	43%	92%
Q9CQR6	Mus musculus	40%	99%
Q9FN02	Arabidopsis thaliana	32%	73%
Q9HFQ2	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	42%	91%
Q9LHE7	Arabidopsis thaliana	39%	99%
Q9M9W3	Arabidopsis thaliana	57%	95%
Q9SX52	Arabidopsis thaliana	39%	99%
Q9U9A3	Dictyostelium discoideum	38%	99%
Q9UW86	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	61%	98%
Q9XGH7	Nicotiana tabacum	41%	96%
Q9XTT8	Caenorhabditis elegans	42%	94%
Q9XW79	Caenorhabditis elegans	42%	90%
Q9XZE5	Dictyostelium discoideum	44%	98%
Q9Y0B7	Dictyostelium discoideum	41%	99%
Q9ZSE4	Hevea brasiliensis	42%	98%
V5AUW3	Trypanosoma cruzi	53%	91%
V5B3V2	Trypanosoma cruzi	36%	79%
V5B5K9	Trypanosoma cruzi	40%	90%
V5B8G5	Trypanosoma cruzi	42%	89%
V5BBR3	Trypanosoma cruzi	32%	77%
V5BGM0	Trypanosoma cruzi	41%	76%
V5BKU4	Trypanosoma cruzi	58%	99%
V5BQD7	Trypanosoma cruzi	33%	69%
V5D2G9	Trypanosoma cruzi	59%	86%
V5DAX7	Trypanosoma cruzi	90%	100%
V5DCW3	Trypanosoma cruzi	38%	98%
V5DIG8	Trypanosoma cruzi	33%	69%
V5DMS5	Trypanosoma cruzi	34%	98%