Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HAE2_LEIBR

TriTrypDb:

LbrM.20.0250 , LBRM2903_200005800

Length:

1322

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HAE2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0010941	regulation of cell death	4	2
GO:0042981	regulation of apoptotic process	6	2
GO:0043067	regulation of programmed cell death	5	2
GO:0050789	regulation of biological process	2	2
GO:0050794	regulation of cellular process	3	2
GO:0065007	biological regulation	1	2

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	446	450	PF00656	0.635
CLV_C14_Caspase3-7	470	474	PF00656	0.679
CLV_C14_Caspase3-7	572	576	PF00656	0.452
CLV_NRD_NRD_1	1195	1197	PF00675	0.433
CLV_NRD_NRD_1	1239	1241	PF00675	0.609
CLV_NRD_NRD_1	1289	1291	PF00675	0.585
CLV_NRD_NRD_1	284	286	PF00675	0.691
CLV_NRD_NRD_1	301	303	PF00675	0.700
CLV_NRD_NRD_1	331	333	PF00675	0.647
CLV_NRD_NRD_1	367	369	PF00675	0.734

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6H4	Leptomonas seymouri	42%	93%
A0A3Q8IF73	Leishmania donovani	76%	99%
A4I9J4	Leishmania infantum	76%	99%
E9B4J2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	75%	99%
Q4Q3I4	Leishmania major	74%	100%

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