Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

protein kinase, putative

Species:

Leishmania braziliensis

UniProt:

A4HAC8_LEIBR

TriTrypDb:

LbrM.20.0110 , LBRM2903_200007900

Length:

340

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HAC8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HAC8

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	11
GO:0006793	phosphorus metabolic process	3	11
GO:0006796	phosphate-containing compound metabolic process	4	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0008152	metabolic process	1	11
GO:0009987	cellular process	1	11
GO:0016310	phosphorylation	5	11
GO:0019538	protein metabolic process	3	11
GO:0036211	protein modification process	4	11
GO:0043170	macromolecule metabolic process	3	11
GO:0043412	macromolecule modification	4	11
GO:0044237	cellular metabolic process	2	11
GO:0044238	primary metabolic process	2	11
GO:0071704	organic substance metabolic process	2	11
GO:1901564	organonitrogen compound metabolic process	3	11

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003824	catalytic activity	1	11
GO:0004672	protein kinase activity	3	11
GO:0004674	protein serine/threonine kinase activity	4	10
GO:0005488	binding	1	11
GO:0005524	ATP binding	5	11
GO:0016301	kinase activity	4	11
GO:0016740	transferase activity	2	11
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	11
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	11
GO:0017076	purine nucleotide binding	4	11
GO:0030554	adenyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032559	adenyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:0140096	catalytic activity, acting on a protein	2	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	149	153	PF00656	0.423
CLV_C14_Caspase3-7	99	103	PF00656	0.423
CLV_PCSK_KEX2_1	272	274	PF00082	0.384
CLV_PCSK_KEX2_1	68	70	PF00082	0.311
CLV_PCSK_PC1ET2_1	272	274	PF00082	0.454
CLV_PCSK_PC1ET2_1	68	70	PF00082	0.311
CLV_PCSK_PC7_1	64	70	PF00082	0.423
CLV_PCSK_SKI1_1	145	149	PF00082	0.452
CLV_PCSK_SKI1_1	296	300	PF00082	0.423
CLV_PCSK_SKI1_1	64	68	PF00082	0.344
CLV_PCSK_SKI1_1	69	73	PF00082	0.315
DOC_CDC14_PxL_1	318	326	PF14671	0.541
DOC_PP2B_LxvP_1	111	114	PF13499	0.213
DOC_PP4_FxxP_1	198	201	PF00568	0.423
DOC_USP7_MATH_1	23	27	PF00917	0.583
DOC_USP7_MATH_1	278	282	PF00917	0.382
DOC_USP7_MATH_1	334	338	PF00917	0.407
DOC_USP7_MATH_2	258	264	PF00917	0.213
DOC_USP7_UBL2_3	296	300	PF12436	0.365
DOC_WW_Pin1_4	135	140	PF00397	0.450
DOC_WW_Pin1_4	162	167	PF00397	0.311
LIG_14-3-3_CanoR_1	217	221	PF00244	0.354
LIG_APCC_ABBA_1	251	256	PF00400	0.330
LIG_APCC_ABBA_1	85	90	PF00400	0.423
LIG_APCC_ABBAyCdc20_2	68	74	PF00400	0.454
LIG_deltaCOP1_diTrp_1	115	122	PF00928	0.384
LIG_eIF4E_1	39	45	PF01652	0.330
LIG_FHA_1	181	187	PF00498	0.458
LIG_FHA_1	28	34	PF00498	0.311
LIG_FHA_1	293	299	PF00498	0.355
LIG_FHA_2	236	242	PF00498	0.302
LIG_FHA_2	97	103	PF00498	0.381
LIG_GBD_Chelix_1	97	105	PF00786	0.213
LIG_LIR_Apic_2	195	201	PF02991	0.330
LIG_LIR_Apic_2	219	225	PF02991	0.311
LIG_LIR_Gen_1	115	122	PF02991	0.311
LIG_LIR_Gen_1	146	155	PF02991	0.423
LIG_LIR_Gen_1	38	45	PF02991	0.399
LIG_LIR_Gen_1	47	57	PF02991	0.357
LIG_LIR_Nem_3	146	151	PF02991	0.423
LIG_LIR_Nem_3	17	21	PF02991	0.641
LIG_LIR_Nem_3	284	289	PF02991	0.353
LIG_LIR_Nem_3	38	42	PF02991	0.399
LIG_LIR_Nem_3	47	53	PF02991	0.357
LIG_SH2_CRK	39	43	PF00017	0.404
LIG_SH2_CRK	50	54	PF00017	0.348
LIG_SH2_GRB2like	131	134	PF00017	0.330
LIG_SH2_NCK_1	57	61	PF00017	0.423
LIG_SH2_PTP2	250	253	PF00017	0.423
LIG_SH2_SRC	100	103	PF00017	0.423
LIG_SH2_STAP1	50	54	PF00017	0.384
LIG_SH2_STAT5	100	103	PF00017	0.423
LIG_SH2_STAT5	131	134	PF00017	0.330
LIG_SH2_STAT5	250	253	PF00017	0.311
LIG_SH2_STAT5	4	7	PF00017	0.623
LIG_SH2_STAT5	70	73	PF00017	0.414
LIG_SH2_STAT5	96	99	PF00017	0.423
LIG_SH3_3	106	112	PF00018	0.336
LIG_TRAF2_1	127	130	PF00917	0.454
LIG_TRAF2_1	203	206	PF00917	0.454
LIG_TRFH_1	5	9	PF08558	0.675
LIG_TYR_ITIM	248	253	PF00017	0.330
LIG_TYR_ITIM	37	42	PF00017	0.336
LIG_WRC_WIRS_1	15	20	PF05994	0.575
MOD_CK1_1	216	222	PF00069	0.442
MOD_CK2_1	124	130	PF00069	0.461
MOD_CK2_1	140	146	PF00069	0.354
MOD_CK2_1	200	206	PF00069	0.321
MOD_CK2_1	278	284	PF00069	0.336
MOD_CK2_1	307	313	PF00069	0.359
MOD_GlcNHglycan	142	145	PF01048	0.213
MOD_GlcNHglycan	192	195	PF01048	0.303
MOD_GlcNHglycan	25	28	PF01048	0.561
MOD_GlcNHglycan	332	335	PF01048	0.518
MOD_GlcNHglycan	38	42	PF01048	0.341
MOD_GSK3_1	162	169	PF00069	0.311
MOD_GSK3_1	205	212	PF00069	0.410
MOD_GSK3_1	23	30	PF00069	0.525
MOD_GSK3_1	292	299	PF00069	0.387
MOD_GSK3_1	330	337	PF00069	0.478
MOD_GSK3_1	96	103	PF00069	0.379
MOD_N-GLC_1	58	63	PF02516	0.386
MOD_NEK2_1	180	185	PF00069	0.321
MOD_NEK2_1	72	77	PF00069	0.431
MOD_NMyristoyl	1	7	PF02799	0.559
MOD_PIKK_1	160	166	PF00454	0.354
MOD_PIKK_1	72	78	PF00454	0.342
MOD_PKA_2	216	222	PF00069	0.354
MOD_Plk_1	205	211	PF00069	0.332
MOD_Plk_1	37	43	PF00069	0.376
MOD_Plk_2-3	124	130	PF00069	0.423
MOD_Plk_2-3	205	211	PF00069	0.213
MOD_Plk_2-3	260	266	PF00069	0.213
MOD_Plk_2-3	307	313	PF00069	0.359
MOD_Plk_4	216	222	PF00069	0.303
MOD_Plk_4	96	102	PF00069	0.287
MOD_ProDKin_1	135	141	PF00069	0.450
MOD_ProDKin_1	162	168	PF00069	0.311
MOD_SUMO_rev_2	169	175	PF00179	0.311
MOD_SUMO_rev_2	232	240	PF00179	0.384
TRG_ENDOCYTIC_2	250	253	PF00928	0.311
TRG_ENDOCYTIC_2	39	42	PF00928	0.404
TRG_ENDOCYTIC_2	4	7	PF00928	0.636
TRG_ENDOCYTIC_2	50	53	PF00928	0.348
TRG_ENDOCYTIC_2	88	91	PF00928	0.412
TRG_ER_diArg_1	326	329	PF00400	0.502
TRG_ER_diArg_1	336	339	PF00400	0.459
TRG_NLS_MonoExtN_4	271	276	PF00514	0.454

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P215	Leptomonas seymouri	29%	100%
A0A0N0P2E2	Leptomonas seymouri	27%	89%
A0A0N0P3Z9	Leptomonas seymouri	29%	96%
A0A0N0P7D2	Leptomonas seymouri	29%	100%
A0A0N1HT76	Leptomonas seymouri	29%	76%
A0A0N1HWQ2	Leptomonas seymouri	23%	100%
A0A0N1ILF6	Leptomonas seymouri	78%	100%
A0A0N1IM47	Leptomonas seymouri	28%	93%
A0A0N1PD05	Leptomonas seymouri	24%	76%
A0A0S4IHW4	Bodo saltans	25%	76%
A0A0S4IKH2	Bodo saltans	27%	69%
A0A0S4IMB7	Bodo saltans	25%	77%
A0A0S4IQ75	Bodo saltans	28%	67%
A0A0S4IRZ7	Bodo saltans	29%	69%
A0A0S4IX86	Bodo saltans	28%	79%
A0A0S4IXR9	Bodo saltans	28%	73%
A0A0S4J7K4	Bodo saltans	27%	70%
A0A0S4JBR3	Bodo saltans	24%	100%
A0A0S4JBY0	Bodo saltans	43%	99%
A0A0S4JF22	Bodo saltans	26%	95%
A0A0S4JK24	Bodo saltans	30%	78%
A0A0S4JNA1	Bodo saltans	27%	69%
A0A0S4JPZ1	Bodo saltans	27%	76%
A0A0S4JUJ2	Bodo saltans	26%	100%
A0A1X0NFW4	Trypanosomatidae	27%	72%
A0A1X0NIA0	Trypanosomatidae	28%	79%
A0A1X0NIX2	Trypanosomatidae	27%	77%
A0A1X0NJV4	Trypanosomatidae	27%	66%
A0A1X0NKA1	Trypanosomatidae	30%	77%
A0A1X0NLC8	Trypanosomatidae	29%	72%
A0A1X0NRZ9	Trypanosomatidae	25%	92%
A0A1X0NY93	Trypanosomatidae	26%	87%
A0A1X0P1A2	Trypanosomatidae	26%	74%
A0A1X0P246	Trypanosomatidae	27%	79%
A0A1X0P527	Trypanosomatidae	27%	77%
A0A1X0P549	Trypanosomatidae	27%	72%
A0A1X0P5U3	Trypanosomatidae	26%	66%
A0A1X0P6V1	Trypanosomatidae	25%	100%
A0A1X0P6Z5	Trypanosomatidae	32%	96%
A0A1X0P8A0	Trypanosomatidae	29%	100%
A0A1X0P919	Trypanosomatidae	27%	91%
A0A1X0P963	Trypanosomatidae	29%	70%
A0A1X0P9C1	Trypanosomatidae	53%	100%
A0A1X0P9C4	Trypanosomatidae	26%	68%
A0A1X0PAW2	Trypanosomatidae	29%	96%
A0A3Q8IAQ1	Leishmania donovani	27%	95%
A0A3Q8IC87	Leishmania donovani	25%	92%
A0A3Q8IEH3	Leishmania donovani	23%	100%
A0A3Q8IFK8	Leishmania donovani	27%	77%
A0A3Q8IFW0	Leishmania donovani	28%	79%
A0A3Q8II44	Leishmania donovani	27%	95%
A0A3R7K109	Trypanosoma rangeli	27%	72%
A0A3R7KCZ4	Trypanosoma rangeli	28%	84%
A0A3R7KMF0	Trypanosoma rangeli	26%	96%
A0A3R7KRP1	Trypanosoma rangeli	25%	71%
A0A3R7L9Q6	Trypanosoma rangeli	29%	96%
A0A3R7M5C7	Trypanosoma rangeli	23%	100%
A0A3R7M819	Trypanosoma rangeli	24%	97%
A0A3R7MKG5	Trypanosoma rangeli	30%	77%
A0A3R7N4D8	Trypanosoma rangeli	25%	84%
A0A3R7N5S4	Trypanosoma rangeli	27%	90%
A0A3R7NLI6	Trypanosoma rangeli	28%	92%
A0A3R7R6T1	Trypanosoma rangeli	51%	100%
A0A3S5H606	Leishmania donovani	24%	100%
A0A3S5H725	Leishmania donovani	28%	96%
A0A3S7WR45	Leishmania donovani	26%	88%
A0A3S7X6T8	Leishmania donovani	24%	76%
A0A3S7X7D5	Leishmania donovani	84%	100%
A0A3S7X7Y2	Leishmania donovani	27%	88%
A0A422N701	Trypanosoma rangeli	28%	76%
A0A422NUF0	Trypanosoma rangeli	26%	85%
A0A422P292	Trypanosoma rangeli	30%	100%
A0A422P4L8	Trypanosoma rangeli	28%	79%
A0AUV4	Mus musculus	31%	67%
A2BD05	Sus scrofa	29%	100%
A2XFF4	Oryza sativa subsp. indica	27%	67%
A3LN91	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	27%	88%
A4H641	Leishmania braziliensis	26%	88%
A4H9D1	Leishmania braziliensis	28%	96%
A4HAS1	Leishmania braziliensis	26%	88%
A4HCD7	Leishmania braziliensis	24%	80%
A4HCE6	Leishmania braziliensis	28%	95%
A4HG92	Leishmania braziliensis	23%	100%
A4HJT5	Leishmania braziliensis	27%	77%
A4HLR0	Leishmania braziliensis	25%	76%
A4HNR5	Leishmania braziliensis	29%	100%
A4HQG8	Leishmania braziliensis	26%	95%
A4HTB4	Leishmania infantum	24%	100%
A4HTU3	Leishmania infantum	27%	71%
A4HUG1	Leishmania infantum	26%	88%
A4HXQ3	Leishmania infantum	28%	96%
A4HZV1	Leishmania infantum	25%	92%
A4HZW8	Leishmania infantum	27%	95%
A4I3C6	Leishmania infantum	23%	100%
A4I7A1	Leishmania infantum	27%	77%
A4I7C4	Leishmania infantum	28%	79%
A4I960	Leishmania infantum	24%	76%
A4I9H1	Leishmania infantum	84%	100%
A4I9Y5	Leishmania infantum	27%	88%
A4ICA4	Leishmania infantum	27%	95%
A4ICT0	Leishmania infantum	29%	100%
A5GFW1	Sus scrofa	26%	85%
A8XJW8	Caenorhabditis briggsae	25%	69%
A9SR33	Physcomitrium patens	26%	99%
B0LT89	Rattus norvegicus	27%	79%
B6DTE5	Bodo saltans	31%	97%
B8BBT7	Oryza sativa subsp. indica	27%	67%
C0HKC8	Mus musculus	27%	67%
C0HKC9	Mus musculus	27%	67%
C9ZIN1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	68%
C9ZIZ0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	75%
C9ZKE1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	84%
C9ZKZ8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	72%
C9ZMH9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	77%
C9ZUD1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	99%
C9ZW46	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	72%
C9ZW68	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	97%
C9ZWK2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	77%
D0A032	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	97%
D0A2M5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
D0A8X3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	92%
D3ZBE5	Rattus norvegicus	25%	100%
D4AE59	Rattus norvegicus	26%	78%
E8NHS0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	95%
E9ALA7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9ARG4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	96%
E9ASH4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AVR5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	92%
E9AVS7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	95%
E9B296	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	77%
E9B2B7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	79%
E9B436	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	76%
E9B4G9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
E9B4Z4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	88%
G5EDF7	Caenorhabditis elegans	24%	100%
O00506	Homo sapiens	25%	80%
O08875	Rattus norvegicus	30%	79%
O09110	Mus musculus	26%	98%
O14047	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	100%
O15865	Plasmodium falciparum (isolate K1 / Thailand)	28%	66%
O22971	Arabidopsis thaliana	29%	68%
O35942	Mus musculus	27%	77%
O55076	Cricetulus griseus	32%	100%
O60145	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	29%	85%
O61125	Dictyostelium discoideum	26%	74%
O75716	Homo sapiens	24%	100%
O88697	Mus musculus	25%	100%
O96526	Leishmania major	29%	100%
P04551	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	100%
P06493	Homo sapiens	30%	100%
P06784	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	66%
P08092	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	72%
P10506	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
P11440	Mus musculus	31%	100%
P13863	Gallus gallus	31%	100%
P18431	Drosophila melanogaster	28%	66%
P23437	Xenopus laevis	31%	100%
P23572	Drosophila melanogaster	29%	100%
P23573	Drosophila melanogaster	29%	100%
P24033	Xenopus laevis	30%	100%
P24941	Homo sapiens	32%	100%
P25859	Arabidopsis thaliana	27%	100%
P32491	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	67%
P34556	Caenorhabditis elegans	27%	100%
P35567	Xenopus laevis	31%	100%
P39951	Rattus norvegicus	31%	100%
P43063	Candida albicans (strain SC5314 / ATCC MYA-2876)	28%	100%
P43450	Carassius auratus	30%	100%
P45985	Homo sapiens	28%	85%
P46734	Homo sapiens	26%	98%
P46892	Rattus norvegicus	30%	78%
P47809	Mus musculus	28%	86%
P48734	Bos taurus	31%	100%
P48963	Mesocricetus auratus	31%	100%
P49071	Drosophila melanogaster	28%	95%
P49615	Mus musculus	30%	100%
P51955	Homo sapiens	28%	76%
P51956	Homo sapiens	30%	67%
P51958	Carassius auratus	32%	100%
P52564	Homo sapiens	26%	100%
P54665	Trypanosoma brucei brucei	28%	99%
P54666	Trypanosoma brucei brucei	28%	100%
P54743	Mycobacterium leprae (strain TN)	25%	78%
P57760	Rattus norvegicus	24%	100%
P59895	Rattus norvegicus	29%	100%
P70236	Mus musculus	26%	100%
P9WI62	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	26%	85%
P9WI63	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	26%	85%
Q00526	Homo sapiens	33%	100%
Q00532	Homo sapiens	28%	95%
Q00535	Homo sapiens	30%	100%
Q02399	Bos taurus	30%	100%
Q03114	Rattus norvegicus	30%	100%
Q0GGW5	Gallus gallus	28%	77%
Q0JI49	Oryza sativa subsp. japonica	27%	68%
Q10078	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	99%
Q10LQ2	Oryza sativa subsp. japonica	29%	75%
Q10SC8	Oryza sativa subsp. japonica	28%	75%
Q12003	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	93%
Q15831	Homo sapiens	26%	79%
Q2QMI0	Oryza sativa subsp. japonica	27%	75%
Q2QY53	Oryza sativa subsp. japonica	27%	78%
Q2QYM3	Oryza sativa subsp. japonica	27%	77%
Q2RAX3	Oryza sativa subsp. japonica	27%	75%
Q2RBF0	Oryza sativa subsp. japonica	27%	78%
Q2V419	Arabidopsis thaliana	27%	100%
Q2V452	Arabidopsis thaliana	27%	77%
Q32PP3	Danio rerio	25%	100%
Q38774	Antirrhinum majus	28%	100%
Q3SWY6	Bos taurus	25%	80%
Q4Q0B0	Leishmania major	27%	95%
Q4Q2Z2	Leishmania major	27%	88%
Q4Q3K6	Leishmania major	82%	100%
Q4Q3Y9	Leishmania major	24%	76%
Q4Q5T9	Leishmania major	28%	79%
Q4Q5W2	Leishmania major	27%	77%
Q4QBQ2	Leishmania major	28%	95%
Q4QBR6	Leishmania major	25%	91%
Q4QE15	Leishmania major	28%	96%
Q4QHG6	Leishmania major	26%	88%
Q4QIJ7	Leishmania major	24%	100%
Q54QD5	Dictyostelium discoideum	25%	70%
Q54RB2	Dictyostelium discoideum	27%	95%
Q556S2	Dictyostelium discoideum	27%	66%
Q55BN8	Dictyostelium discoideum	24%	81%
Q5E9X2	Bos taurus	26%	100%
Q5E9Y0	Bos taurus	32%	100%
Q5KQF5	Oryza sativa subsp. japonica	27%	75%
Q5R754	Pongo abelii	26%	69%
Q5RCH1	Pongo abelii	30%	100%
Q5W736	Oryza sativa subsp. japonica	30%	74%
Q5XIT0	Rattus norvegicus	26%	67%
Q5Z6X0	Oryza sativa subsp. japonica	28%	66%
Q63686	Rattus norvegicus	30%	69%
Q63699	Rattus norvegicus	32%	100%
Q64261	Mus musculus	29%	100%
Q66HE7	Rattus norvegicus	28%	97%
Q68Y49	Oryza sativa subsp. japonica	29%	67%
Q6ERS4	Oryza sativa subsp. japonica	32%	75%
Q6H7U5	Oryza sativa subsp. japonica	28%	69%
Q6NU47	Xenopus laevis	26%	100%
Q6NU98	Xenopus laevis	27%	100%
Q6X4A2	Oryza sativa subsp. japonica	28%	76%
Q6ZLP5	Oryza sativa subsp. japonica	27%	76%
Q75V57	Oryza sativa subsp. japonica	31%	94%
Q7TYY6	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	26%	85%
Q7X996	Oryza sativa subsp. japonica	27%	77%
Q80YP0	Mus musculus	31%	100%
Q84VQ3	Arabidopsis thaliana	28%	77%
Q852Q0	Oryza sativa subsp. japonica	27%	67%
Q852Q1	Oryza sativa subsp. japonica	27%	67%
Q8AYC9	Gallus gallus	26%	71%
Q8C0N0	Mus musculus	28%	68%
Q8CEQ0	Mus musculus	29%	97%
Q8ICR0	Plasmodium falciparum (isolate 3D7)	28%	66%
Q8L4P8	Oryza sativa subsp. japonica	30%	100%
Q8N165	Homo sapiens	26%	100%
Q8NU97	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	26%	72%
Q8QZR7	Mus musculus	26%	100%
Q8SRF5	Encephalitozoon cuniculi (strain GB-M1)	30%	100%
Q8W1D5	Arabidopsis thaliana	29%	70%
Q8W490	Arabidopsis thaliana	24%	72%
Q8WQ45	Leishmania donovani	29%	100%
Q92207	Candida albicans (strain SC5314 / ATCC MYA-2876)	26%	90%
Q92772	Homo sapiens	26%	69%
Q93VD3	Arabidopsis thaliana	28%	71%
Q93VK0	Arabidopsis thaliana	29%	100%
Q96PN8	Homo sapiens	30%	100%
Q99JT2	Mus musculus	26%	82%
Q99KH8	Mus musculus	26%	79%
Q9BYT3	Homo sapiens	24%	66%
Q9C562	Arabidopsis thaliana	28%	71%
Q9D2E1	Mus musculus	30%	100%
Q9DG98	Oryzias luzonensis	31%	100%
Q9DGA2	Oryzias javanicus	31%	100%
Q9DGA5	Oryzias curvinotus	30%	100%
Q9DGD3	Oryzias latipes	31%	100%
Q9DGE0	Danio rerio	26%	94%
Q9ES70	Mus musculus	29%	100%
Q9ES74	Mus musculus	26%	100%
Q9FJ54	Arabidopsis thaliana	30%	77%
Q9HC98	Homo sapiens	29%	100%
Q9HGY5	Candida albicans	28%	100%
Q9LDI3	Arabidopsis thaliana	28%	76%
Q9LEU7	Arabidopsis thaliana	29%	76%
Q9LWM4	Oryza sativa subsp. japonica	29%	74%
Q9LYQ8	Arabidopsis thaliana	27%	75%
Q9MAM1	Arabidopsis thaliana	27%	76%
Q9N2N1	Leishmania major	23%	100%
Q9NB31	Caenorhabditis elegans	25%	68%
Q9P289	Homo sapiens	26%	82%
Q9QYZ3	Mus musculus	28%	70%
Q9QYZ4	Mus musculus	28%	70%
Q9QYZ6	Mus musculus	28%	67%
Q9S7U9	Arabidopsis thaliana	25%	94%
Q9SEZ7	Arabidopsis thaliana	30%	72%
Q9UV50	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	27%	88%
Q9W739	Rana dybowskii	31%	100%
Q9WTK7	Mus musculus	26%	78%
Q9Y6E0	Homo sapiens	26%	77%
Q9Z2W1	Mus musculus	25%	80%
V5B472	Trypanosoma cruzi	52%	100%
V5B6E9	Trypanosoma cruzi	30%	96%
V5B871	Trypanosoma cruzi	26%	79%
V5B9R6	Trypanosoma cruzi	25%	97%
V5BAZ8	Trypanosoma cruzi	26%	89%
V5BC28	Trypanosoma cruzi	29%	68%
V5BC61	Trypanosoma cruzi	28%	100%
V5BCH2	Trypanosoma cruzi	24%	87%
V5BKJ3	Trypanosoma cruzi	28%	96%
V5BMH5	Trypanosoma cruzi	28%	100%
V5BNV8	Trypanosoma cruzi	24%	100%
V5BV49	Trypanosoma cruzi	30%	100%
V5C224	Trypanosoma cruzi	28%	68%
V5D579	Trypanosoma cruzi	26%	79%
V5D9M1	Trypanosoma cruzi	29%	93%