Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved (fragment)

Species:

Leishmania braziliensis

UniProt:

A4HAB7_LEIBR

TriTrypDb:

LbrM.19.1940 , LBRM2903_190014500

Length:

204

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 3, no: 0
NetGPI	no	yes: 0, no: 3

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

Expansion

Sequence features

A4HAB7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HAB7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	3	7	PF00082	0.541
DOC_CKS1_1	168	173	PF01111	0.267
DOC_MAPK_MEF2A_6	103	112	PF00069	0.392
DOC_PP4_FxxP_1	201	204	PF00568	0.311
DOC_USP7_MATH_1	178	182	PF00917	0.374
DOC_USP7_MATH_1	25	29	PF00917	0.354
DOC_WW_Pin1_4	164	169	PF00397	0.267
DOC_WW_Pin1_4	89	94	PF00397	0.509
LIG_14-3-3_CanoR_1	154	164	PF00244	0.245
LIG_14-3-3_CanoR_1	53	62	PF00244	0.283
LIG_BIR_II_1	1	5	PF00653	0.372
LIG_FHA_1	156	162	PF00498	0.243
LIG_FHA_1	171	177	PF00498	0.304
LIG_FHA_1	198	204	PF00498	0.354
LIG_FHA_1	72	78	PF00498	0.186
LIG_FHA_2	90	96	PF00498	0.512
LIG_LIR_Apic_2	199	204	PF02991	0.301
LIG_LIR_Gen_1	187	197	PF02991	0.273
LIG_LIR_Nem_3	56	61	PF02991	0.266
LIG_LYPXL_S_1	62	66	PF13949	0.485
LIG_SH2_CRK	126	130	PF00017	0.296
LIG_SH2_GRB2like	149	152	PF00017	0.253
LIG_SH2_SRC	61	64	PF00017	0.267
LIG_SH2_STAP1	189	193	PF00017	0.347
LIG_SH2_STAT5	105	108	PF00017	0.501
LIG_SH2_STAT5	149	152	PF00017	0.240
LIG_SH2_STAT5	61	64	PF00017	0.262
LIG_SH3_3	165	171	PF00018	0.267
LIG_SUMO_SIM_anti_2	74	79	PF11976	0.186
LIG_TRAF2_1	92	95	PF00917	0.513
LIG_TRFH_1	60	64	PF08558	0.265
LIG_TYR_ITIM	124	129	PF00017	0.433
LIG_UBA3_1	44	51	PF00899	0.261
MOD_CK1_1	156	162	PF00069	0.356
MOD_CK1_1	167	173	PF00069	0.373
MOD_CK1_1	196	202	PF00069	0.310
MOD_CK1_1	40	46	PF00069	0.312
MOD_CK2_1	137	143	PF00069	0.294
MOD_CK2_1	89	95	PF00069	0.561
MOD_GlcNHglycan	164	167	PF01048	0.492
MOD_GlcNHglycan	23	26	PF01048	0.523
MOD_GlcNHglycan	89	92	PF01048	0.356
MOD_GSK3_1	155	162	PF00069	0.333
MOD_GSK3_1	193	200	PF00069	0.436
MOD_GSK3_1	21	28	PF00069	0.358
MOD_GSK3_1	33	40	PF00069	0.276
MOD_N-GLC_1	143	148	PF02516	0.496
MOD_N-GLC_1	150	155	PF02516	0.486
MOD_N-GLC_1	162	167	PF02516	0.553
MOD_N-GLC_1	184	189	PF02516	0.451
MOD_N-GLC_1	40	45	PF02516	0.471
MOD_NEK2_1	131	136	PF00069	0.255
MOD_NEK2_1	150	155	PF00069	0.199
MOD_NEK2_1	18	23	PF00069	0.399
MOD_NEK2_1	33	38	PF00069	0.246
MOD_NEK2_1	71	76	PF00069	0.179
MOD_PIKK_1	53	59	PF00454	0.263
MOD_PKA_2	153	159	PF00069	0.234
MOD_PKA_2	193	199	PF00069	0.295
MOD_Plk_1	143	149	PF00069	0.286
MOD_Plk_1	150	156	PF00069	0.353
MOD_Plk_1	184	190	PF00069	0.258
MOD_Plk_1	40	46	PF00069	0.270
MOD_Plk_2-3	143	149	PF00069	0.355
MOD_Plk_4	156	162	PF00069	0.243
MOD_Plk_4	40	46	PF00069	0.327
MOD_ProDKin_1	164	170	PF00069	0.265
MOD_ProDKin_1	89	95	PF00069	0.510
MOD_SUMO_rev_2	90	99	PF00179	0.558
TRG_ENDOCYTIC_2	105	108	PF00928	0.501
TRG_ENDOCYTIC_2	126	129	PF00928	0.425
TRG_ENDOCYTIC_2	189	192	PF00928	0.342
TRG_ENDOCYTIC_2	63	66	PF00928	0.285

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4J3F3	Bodo saltans	28%	71%
V5BAX6	Trypanosoma cruzi	40%	93%