RING-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HAB4_LEIBR

TriTrypDb:

LbrM.19.1910 , LBRM2903_190019100 , LBRM2903_190019200

Length:

2630

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005815	microtubule organizing center	2	1
GO:0036064	ciliary basal body	3	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A4HAB4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	1
GO:0008270	zinc ion binding	6	1
GO:0043167	ion binding	2	1
GO:0043169	cation binding	3	1
GO:0046872	metal ion binding	4	1
GO:0046914	transition metal ion binding	5	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1012	1016	PF00656	0.590
CLV_C14_Caspase3-7	1183	1187	PF00656	0.694
CLV_C14_Caspase3-7	1289	1293	PF00656	0.494
CLV_C14_Caspase3-7	1458	1462	PF00656	0.493
CLV_C14_Caspase3-7	1636	1640	PF00656	0.497
CLV_C14_Caspase3-7	173	177	PF00656	0.804
CLV_C14_Caspase3-7	194	198	PF00656	0.756
CLV_C14_Caspase3-7	2145	2149	PF00656	0.697
CLV_C14_Caspase3-7	2182	2186	PF00656	0.731
CLV_C14_Caspase3-7	2237	2241	PF00656	0.513

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I705	Leptomonas seymouri	44%	100%
A0A3Q8IBD0	Leishmania donovani	69%	98%
A4HYD3	Leishmania infantum	69%	98%
E9AS66	Leishmania mexicana (strain MHOM/GT/2001/U1103)	68%	99%
Q4QDA0	Leishmania major	68%	99%

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