Putative kinesin

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Putative kinesin

Gene product:

kinesin, putative (fragment)

Species:

Leishmania braziliensis

UniProt:

A4HA41_LEIBR

TriTrypDb:

LbrM.19.1160 , LBRM2903_190015700

Length:

267

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HA41

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HA41

Function

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Biological processes
Term	Name	Level	Count
GO:0007017	microtubule-based process	2	2
GO:0007018	microtubule-based movement	3	2
GO:0009987	cellular process	1	2

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	2
GO:0003774	cytoskeletal motor activity	1	2
GO:0003777	microtubule motor activity	2	2
GO:0005488	binding	1	2
GO:0005515	protein binding	2	2
GO:0005524	ATP binding	5	2
GO:0008017	microtubule binding	5	2
GO:0008092	cytoskeletal protein binding	3	2
GO:0015631	tubulin binding	4	2
GO:0017076	purine nucleotide binding	4	2

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	12	14	PF00675	0.829
CLV_NRD_NRD_1	171	173	PF00675	0.784
CLV_NRD_NRD_1	189	191	PF00675	0.516
CLV_NRD_NRD_1	23	25	PF00675	0.654
CLV_PCSK_KEX2_1	12	14	PF00082	0.829
CLV_PCSK_KEX2_1	171	173	PF00082	0.784
CLV_PCSK_KEX2_1	189	191	PF00082	0.516
CLV_PCSK_KEX2_1	23	25	PF00082	0.654
CLV_PCSK_PC7_1	8	14	PF00082	0.825
CLV_PCSK_SKI1_1	189	193	PF00082	0.711

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
Q6ZMV9	HUMAN	56%	33%

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