Chromosome partition protein Smc

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HA29_LEIBR

TriTrypDb:

LbrM.19.1030 , LBRM2903_190016200

Length:

301

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HA29

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HA29

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	129	133	PF00656	0.666
CLV_C14_Caspase3-7	252	256	PF00656	0.563
CLV_NRD_NRD_1	151	153	PF00675	0.526
CLV_NRD_NRD_1	288	290	PF00675	0.575
CLV_PCSK_SKI1_1	194	198	PF00082	0.499
CLV_PCSK_SKI1_1	244	248	PF00082	0.616
DEG_APCC_DBOX_1	193	201	PF00400	0.555
DEG_APCC_DBOX_1	243	251	PF00400	0.538
DEG_Nend_UBRbox_2	1	3	PF02207	0.582
DEG_SPOP_SBC_1	294	298	PF00917	0.745
DOC_CYCLIN_yCln2_LP_2	72	78	PF00134	0.439
DOC_USP7_MATH_1	126	130	PF00917	0.674
DOC_USP7_MATH_1	249	253	PF00917	0.575
DOC_USP7_UBL2_3	153	157	PF12436	0.601
DOC_WW_Pin1_4	290	295	PF00397	0.700
LIG_14-3-3_CanoR_1	125	131	PF00244	0.633
LIG_14-3-3_CanoR_1	242	250	PF00244	0.617
LIG_FHA_1	100	106	PF00498	0.609
LIG_FHA_2	271	277	PF00498	0.584
LIG_LIR_Gen_1	255	265	PF02991	0.475
LIG_LIR_Gen_1	269	280	PF02991	0.605
LIG_LIR_Nem_3	205	211	PF02991	0.513
LIG_LIR_Nem_3	255	261	PF02991	0.509
LIG_LIR_Nem_3	263	268	PF02991	0.565
LIG_LIR_Nem_3	269	275	PF02991	0.588
LIG_NRP_CendR_1	300	301	PF00754	0.775
LIG_PCNA_yPIPBox_3	56	69	PF02747	0.624
LIG_SH2_CRK	258	262	PF00017	0.421
LIG_TRAF2_1	210	213	PF00917	0.490
MOD_CDK_SPK_2	290	295	PF00069	0.481
MOD_CK1_1	201	207	PF00069	0.566
MOD_CK1_1	293	299	PF00069	0.703
MOD_CK2_1	185	191	PF00069	0.568
MOD_CK2_1	207	213	PF00069	0.495
MOD_CK2_1	270	276	PF00069	0.519
MOD_GlcNHglycan	187	190	PF01048	0.607
MOD_GlcNHglycan	212	216	PF01048	0.508
MOD_GlcNHglycan	235	239	PF01048	0.612
MOD_GSK3_1	121	128	PF00069	0.574
MOD_GSK3_1	147	154	PF00069	0.399
MOD_GSK3_1	207	214	PF00069	0.494
MOD_GSK3_1	220	227	PF00069	0.484
MOD_GSK3_1	290	297	PF00069	0.668
MOD_NEK2_1	130	135	PF00069	0.591
MOD_NEK2_1	285	290	PF00069	0.627
MOD_NEK2_1	7	12	PF00069	0.539
MOD_NEK2_2	126	131	PF00069	0.556
MOD_PK_1	295	301	PF00069	0.668
MOD_PKA_2	130	136	PF00069	0.614
MOD_PKA_2	151	157	PF00069	0.601
MOD_PKA_2	185	191	PF00069	0.665
MOD_PKA_2	294	300	PF00069	0.532
MOD_Plk_1	234	240	PF00069	0.582
MOD_Plk_4	64	70	PF00069	0.585
MOD_ProDKin_1	290	296	PF00069	0.700
MOD_SUMO_rev_2	98	105	PF00179	0.643
TRG_DiLeu_BaLyEn_6	9	14	PF01217	0.654
TRG_ENDOCYTIC_2	258	261	PF00928	0.423
TRG_ER_diArg_1	299	301	PF00400	0.770
TRG_ER_diArg_1	81	84	PF00400	0.622
TRG_Pf-PMV_PEXEL_1	56	60	PF00026	0.655

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIA8	Leptomonas seymouri	75%	99%
A0A1X0P7A5	Trypanosomatidae	37%	96%
A0A3Q8IB89	Leishmania donovani	85%	99%
A0A422NN36	Trypanosoma rangeli	37%	99%
A4HY92	Leishmania infantum	85%	99%
D0A0M5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
E9AS24	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4QDE9	Leishmania major	83%	100%
V5B7K2	Trypanosoma cruzi	37%	98%