Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HA19_LEIBR

TriTrypDb:

LbrM.19.0930 , LBRM2903_190015000

Length:


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6
GO:0005635	nuclear envelope	4	1
GO:0005737	cytoplasm	2	1
GO:0031967	organelle envelope	3	1
GO:0031975	envelope	2	1

A4HA19

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HA19


Leishmania	From	To	Domain/Motif	Score
DOC_CYCLIN_yCln2_LP_2	3	9	PF00134	0.238
DOC_PP2B_LxvP_1	3	6	PF13499	0.238
LIG_Clathr_ClatBox_1	76	80	PF01394	0.642
LIG_eIF4E_1	71	77	PF01652	0.615
LIG_FHA_1	33	39	PF00498	0.629
LIG_LIR_Apic_2	27	32	PF02991	0.637
LIG_LIR_Gen_1	51	60	PF02991	0.562
LIG_LIR_Nem_3	51	55	PF02991	0.565
LIG_SH2_NCK_1	29	33	PF00017	0.564
LIG_SH2_SRC	45	48	PF00017	0.571
LIG_SH2_STAT5	45	48	PF00017	0.573
LIG_SH3_3	76	82	PF00018	0.642
LIG_SUMO_SIM_par_1	12	17	PF11976	0.330
LIG_SUMO_SIM_par_1	72	80	PF11976	0.626
LIG_WRC_WIRS_1	49	54	PF05994	0.563
MOD_GSK3_1	32	39	PF00069	0.630
MOD_GSK3_1	5	12	PF00069	0.251
MOD_NEK2_1	9	14	PF00069	0.394
MOD_PIKK_1	83	89	PF00454	0.609
MOD_Plk_1	72	78	PF00069	0.619
MOD_Plk_4	72	78	PF00069	0.630
MOD_Plk_4	9	15	PF00069	0.253


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1K0	Leptomonas seymouri	62%	97%
A0A3Q8IA80	Leishmania donovani	68%	97%
A4HY82	Leishmania infantum	68%	97%
E9AS13	Leishmania mexicana (strain MHOM/GT/2001/U1103)	68%	97%
Q4QDG0	Leishmania major	70%	100%