LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HA09_LEIBR
TriTrypDb:
LbrM.19.0830 , LBRM2903_190013000 *
Length:
1014

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HA09
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HA09

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 122 126 PF00656 0.861
CLV_C14_Caspase3-7 459 463 PF00656 0.846
CLV_C14_Caspase3-7 615 619 PF00656 0.860
CLV_C14_Caspase3-7 629 633 PF00656 0.638
CLV_C14_Caspase3-7 720 724 PF00656 0.828
CLV_C14_Caspase3-7 8 12 PF00656 0.876
CLV_C14_Caspase3-7 90 94 PF00656 0.878
CLV_C14_Caspase3-7 96 100 PF00656 0.761
CLV_NRD_NRD_1 1009 1011 PF00675 0.519
CLV_NRD_NRD_1 735 737 PF00675 0.736
CLV_NRD_NRD_1 991 993 PF00675 0.770
CLV_NRD_NRD_1 998 1000 PF00675 0.642
CLV_PCSK_KEX2_1 1009 1011 PF00082 0.554
CLV_PCSK_KEX2_1 251 253 PF00082 0.781
CLV_PCSK_KEX2_1 735 737 PF00082 0.736
CLV_PCSK_KEX2_1 779 781 PF00082 0.775
CLV_PCSK_KEX2_1 993 995 PF00082 0.761
CLV_PCSK_KEX2_1 998 1000 PF00082 0.677
CLV_PCSK_PC1ET2_1 251 253 PF00082 0.781
CLV_PCSK_PC1ET2_1 779 781 PF00082 0.775
CLV_PCSK_PC1ET2_1 993 995 PF00082 0.761
CLV_PCSK_PC7_1 994 1000 PF00082 0.759
CLV_PCSK_SKI1_1 272 276 PF00082 0.757
CLV_PCSK_SKI1_1 306 310 PF00082 0.822
CLV_PCSK_SKI1_1 373 377 PF00082 0.842
CLV_PCSK_SKI1_1 389 393 PF00082 0.559
CLV_PCSK_SKI1_1 736 740 PF00082 0.713
DEG_APCC_DBOX_1 305 313 PF00400 0.821
DEG_APCC_DBOX_1 388 396 PF00400 0.845
DEG_SPOP_SBC_1 585 589 PF00917 0.878
DEG_SPOP_SBC_1 670 674 PF00917 0.869
DOC_CKS1_1 330 335 PF01111 0.828
DOC_CKS1_1 600 605 PF01111 0.869
DOC_CKS1_1 940 945 PF01111 0.850
DOC_CYCLIN_yCln2_LP_2 52 55 PF00134 0.852
DOC_CYCLIN_yCln2_LP_2 882 888 PF00134 0.726
DOC_MAPK_DCC_7 306 314 PF00069 0.820
DOC_MAPK_gen_1 283 293 PF00069 0.783
DOC_MAPK_gen_1 645 654 PF00069 0.875
DOC_MAPK_gen_1 661 670 PF00069 0.596
DOC_MAPK_MEF2A_6 407 416 PF00069 0.821
DOC_MAPK_MEF2A_6 645 654 PF00069 0.875
DOC_MAPK_RevD_3 765 780 PF00069 0.761
DOC_PP1_RVXF_1 753 759 PF00149 0.694
DOC_PP2B_LxvP_1 110 113 PF13499 0.838
DOC_PP2B_LxvP_1 52 55 PF13499 0.852
DOC_PP2B_LxvP_1 652 655 PF13499 0.866
DOC_PP2B_LxvP_1 657 660 PF13499 0.779
DOC_PP2B_LxvP_1 715 718 PF13499 0.764
DOC_PP4_FxxP_1 531 534 PF00568 0.865
DOC_USP7_MATH_1 197 201 PF00917 0.862
DOC_USP7_MATH_1 221 225 PF00917 0.861
DOC_USP7_MATH_1 227 231 PF00917 0.750
DOC_USP7_MATH_1 250 254 PF00917 0.782
DOC_USP7_MATH_1 274 278 PF00917 0.758
DOC_USP7_MATH_1 362 366 PF00917 0.870
DOC_USP7_MATH_1 4 8 PF00917 0.867
DOC_USP7_MATH_1 61 65 PF00917 0.832
DOC_USP7_MATH_1 638 642 PF00917 0.877
DOC_USP7_MATH_1 648 652 PF00917 0.696
DOC_USP7_MATH_1 679 683 PF00917 0.857
DOC_USP7_MATH_1 837 841 PF00917 0.766
DOC_USP7_MATH_1 848 852 PF00917 0.631
DOC_USP7_MATH_1 864 868 PF00917 0.512
DOC_USP7_MATH_1 931 935 PF00917 0.859
DOC_USP7_MATH_1 955 959 PF00917 0.859
DOC_WW_Pin1_4 182 187 PF00397 0.864
DOC_WW_Pin1_4 329 334 PF00397 0.829
DOC_WW_Pin1_4 354 359 PF00397 0.851
DOC_WW_Pin1_4 43 48 PF00397 0.860
DOC_WW_Pin1_4 440 445 PF00397 0.828
DOC_WW_Pin1_4 519 524 PF00397 0.841
DOC_WW_Pin1_4 526 531 PF00397 0.741
DOC_WW_Pin1_4 563 568 PF00397 0.861
DOC_WW_Pin1_4 574 579 PF00397 0.685
DOC_WW_Pin1_4 599 604 PF00397 0.876
DOC_WW_Pin1_4 634 639 PF00397 0.883
DOC_WW_Pin1_4 655 660 PF00397 0.860
DOC_WW_Pin1_4 925 930 PF00397 0.848
DOC_WW_Pin1_4 932 937 PF00397 0.740
DOC_WW_Pin1_4 939 944 PF00397 0.608
DOC_WW_Pin1_4 963 968 PF00397 0.879
DOC_WW_Pin1_4 982 987 PF00397 0.510
LIG_14-3-3_CanoR_1 252 256 PF00244 0.775
LIG_14-3-3_CanoR_1 286 293 PF00244 0.795
LIG_14-3-3_CanoR_1 373 382 PF00244 0.835
LIG_14-3-3_CanoR_1 384 392 PF00244 0.633
LIG_14-3-3_CanoR_1 403 407 PF00244 0.528
LIG_14-3-3_CanoR_1 471 479 PF00244 0.846
LIG_14-3-3_CanoR_1 681 685 PF00244 0.845
LIG_14-3-3_CanoR_1 757 763 PF00244 0.705
LIG_14-3-3_CanoR_1 839 844 PF00244 0.794
LIG_AP2alpha_1 117 121 PF02296 0.865
LIG_APCC_ABBA_1 684 689 PF00400 0.789
LIG_BIR_III_2 14 18 PF00653 0.878
LIG_BIR_III_2 187 191 PF00653 0.865
LIG_BIR_III_2 695 699 PF00653 0.711
LIG_BIR_III_4 115 119 PF00653 0.856
LIG_EVH1_1 652 656 PF00568 0.862
LIG_EVH1_2 113 117 PF00568 0.833
LIG_FHA_1 140 146 PF00498 0.821
LIG_FHA_1 332 338 PF00498 0.830
LIG_FHA_1 359 365 PF00498 0.867
LIG_FHA_1 434 440 PF00498 0.844
LIG_FHA_1 474 480 PF00498 0.848
LIG_FHA_1 595 601 PF00498 0.883
LIG_FHA_1 615 621 PF00498 0.511
LIG_FHA_1 857 863 PF00498 0.822
LIG_FHA_1 982 988 PF00498 0.832
LIG_FHA_2 120 126 PF00498 0.862
LIG_FHA_2 150 156 PF00498 0.830
LIG_FHA_2 252 258 PF00498 0.775
LIG_FHA_2 330 336 PF00498 0.830
LIG_FHA_2 394 400 PF00498 0.856
LIG_FHA_2 479 485 PF00498 0.865
LIG_FHA_2 58 64 PF00498 0.843
LIG_FHA_2 6 12 PF00498 0.875
LIG_FHA_2 699 705 PF00498 0.682
LIG_FHA_2 718 724 PF00498 0.480
LIG_FHA_2 792 798 PF00498 0.719
LIG_HP1_1 412 416 PF01393 0.809
LIG_Integrin_RGD_1 1012 1014 PF01839 0.849
LIG_LIR_Apic_2 529 534 PF02991 0.860
LIG_LIR_Apic_2 923 929 PF02991 0.841
LIG_LIR_Gen_1 215 225 PF02991 0.871
LIG_LIR_Gen_1 514 523 PF02991 0.850
LIG_LIR_Nem_3 115 120 PF02991 0.856
LIG_LIR_Nem_3 215 220 PF02991 0.878
LIG_LIR_Nem_3 514 518 PF02991 0.860
LIG_LIR_Nem_3 549 555 PF02991 0.827
LIG_LIR_Nem_3 711 715 PF02991 0.718
LIG_LIR_Nem_3 897 902 PF02991 0.723
LIG_LYPXL_yS_3 195 198 PF13949 0.855
LIG_MYND_1 160 164 PF01753 0.856
LIG_MYND_1 655 659 PF01753 0.859
LIG_MYND_3 159 163 PF01753 0.854
LIG_Pex14_1 551 555 PF04695 0.825
LIG_Pex14_2 117 121 PF04695 0.865
LIG_REV1ctd_RIR_1 763 773 PF16727 0.745
LIG_SH2_CRK 877 881 PF00017 0.745
LIG_SH2_CRK 926 930 PF00017 0.850
LIG_SH2_SRC 322 325 PF00017 0.843
LIG_SH2_STAP1 287 291 PF00017 0.792
LIG_SH2_STAP1 832 836 PF00017 0.756
LIG_SH2_STAP1 877 881 PF00017 0.745
LIG_SH2_STAT3 1000 1003 PF00017 0.762
LIG_SH2_STAT5 1000 1003 PF00017 0.762
LIG_SH2_STAT5 1006 1009 PF00017 0.695
LIG_SH2_STAT5 515 518 PF00017 0.860
LIG_SH2_STAT5 562 565 PF00017 0.863
LIG_SH3_1 647 653 PF00018 0.874
LIG_SH3_2 656 661 PF14604 0.865
LIG_SH3_3 155 161 PF00018 0.848
LIG_SH3_3 305 311 PF00018 0.822
LIG_SH3_3 489 495 PF00018 0.862
LIG_SH3_3 50 56 PF00018 0.859
LIG_SH3_3 597 603 PF00018 0.879
LIG_SH3_3 647 653 PF00018 0.874
LIG_SH3_3 713 719 PF00018 0.750
LIG_SH3_3 930 936 PF00018 0.857
LIG_SH3_3 937 943 PF00018 0.738
LIG_SH3_3 951 957 PF00018 0.609
LIG_SH3_CIN85_PxpxPR_1 694 699 PF14604 0.714
LIG_SUMO_SIM_anti_2 390 401 PF11976 0.851
LIG_SUMO_SIM_par_1 390 402 PF11976 0.851
LIG_SUMO_SIM_par_1 606 612 PF11976 0.868
LIG_SUMO_SIM_par_1 884 889 PF11976 0.718
LIG_TRAF2_1 17 20 PF00917 0.874
LIG_TRAF2_1 988 991 PF00917 0.779
LIG_TRFH_1 217 221 PF08558 0.875
LIG_WW_3 658 662 PF00397 0.866
MOD_CDC14_SPxK_1 658 661 PF00782 0.863
MOD_CDK_SPK_2 440 445 PF00069 0.828
MOD_CDK_SPxK_1 655 661 PF00069 0.861
MOD_CK1_1 143 149 PF00069 0.813
MOD_CK1_1 151 157 PF00069 0.694
MOD_CK1_1 177 183 PF00069 0.869
MOD_CK1_1 200 206 PF00069 0.882
MOD_CK1_1 21 27 PF00069 0.616
MOD_CK1_1 236 242 PF00069 0.855
MOD_CK1_1 243 249 PF00069 0.679
MOD_CK1_1 354 360 PF00069 0.853
MOD_CK1_1 393 399 PF00069 0.854
MOD_CK1_1 401 407 PF00069 0.719
MOD_CK1_1 420 426 PF00069 0.480
MOD_CK1_1 440 446 PF00069 0.478
MOD_CK1_1 465 471 PF00069 0.856
MOD_CK1_1 486 492 PF00069 0.862
MOD_CK1_1 566 572 PF00069 0.870
MOD_CK1_1 624 630 PF00069 0.878
MOD_CK1_1 64 70 PF00069 0.796
MOD_CK1_1 671 677 PF00069 0.866
MOD_CK1_1 7 13 PF00069 0.876
MOD_CK1_1 835 841 PF00069 0.759
MOD_CK1_1 851 857 PF00069 0.545
MOD_CK1_1 867 873 PF00069 0.507
MOD_CK1_1 925 931 PF00069 0.849
MOD_CK1_1 935 941 PF00069 0.690
MOD_CK2_1 149 155 PF00069 0.824
MOD_CK2_1 251 257 PF00069 0.778
MOD_CK2_1 329 335 PF00069 0.830
MOD_CK2_1 478 484 PF00069 0.863
MOD_CK2_1 544 550 PF00069 0.839
MOD_CK2_1 624 630 PF00069 0.878
MOD_CK2_1 698 704 PF00069 0.698
MOD_CK2_1 72 78 PF00069 0.792
MOD_CK2_1 722 728 PF00069 0.840
MOD_CK2_1 741 747 PF00069 0.326
MOD_CK2_1 985 991 PF00069 0.798
MOD_DYRK1A_RPxSP_1 927 931 PF00069 0.849
MOD_GlcNHglycan 110 113 PF01048 0.645
MOD_GlcNHglycan 125 128 PF01048 0.593
MOD_GlcNHglycan 199 202 PF01048 0.869
MOD_GlcNHglycan 222 226 PF01048 0.866
MOD_GlcNHglycan 229 232 PF01048 0.747
MOD_GlcNHglycan 23 26 PF01048 0.860
MOD_GlcNHglycan 314 317 PF01048 0.829
MOD_GlcNHglycan 32 35 PF01048 0.691
MOD_GlcNHglycan 364 367 PF01048 0.869
MOD_GlcNHglycan 376 379 PF01048 0.635
MOD_GlcNHglycan 385 388 PF01048 0.659
MOD_GlcNHglycan 423 426 PF01048 0.811
MOD_GlcNHglycan 439 442 PF01048 0.556
MOD_GlcNHglycan 568 571 PF01048 0.876
MOD_GlcNHglycan 614 617 PF01048 0.863
MOD_GlcNHglycan 66 69 PF01048 0.789
MOD_GlcNHglycan 675 678 PF01048 0.860
MOD_GlcNHglycan 720 723 PF01048 0.824
MOD_GlcNHglycan 773 776 PF01048 0.766
MOD_GlcNHglycan 818 821 PF01048 0.731
MOD_GlcNHglycan 862 865 PF01048 0.804
MOD_GlcNHglycan 869 872 PF01048 0.665
MOD_GlcNHglycan 88 92 PF01048 0.881
MOD_GlcNHglycan 889 893 PF01048 0.358
MOD_GlcNHglycan 957 960 PF01048 0.864
MOD_GlcNHglycan 99 102 PF01048 0.669
MOD_GSK3_1 119 126 PF00069 0.862
MOD_GSK3_1 139 146 PF00069 0.472
MOD_GSK3_1 200 207 PF00069 0.881
MOD_GSK3_1 232 239 PF00069 0.868
MOD_GSK3_1 246 253 PF00069 0.544
MOD_GSK3_1 349 356 PF00069 0.855
MOD_GSK3_1 358 365 PF00069 0.704
MOD_GSK3_1 390 397 PF00069 0.849
MOD_GSK3_1 398 405 PF00069 0.717
MOD_GSK3_1 417 424 PF00069 0.481
MOD_GSK3_1 433 440 PF00069 0.564
MOD_GSK3_1 473 480 PF00069 0.846
MOD_GSK3_1 57 64 PF00069 0.845
MOD_GSK3_1 612 619 PF00069 0.862
MOD_GSK3_1 634 641 PF00069 0.883
MOD_GSK3_1 666 673 PF00069 0.874
MOD_GSK3_1 68 75 PF00069 0.592
MOD_GSK3_1 718 725 PF00069 0.814
MOD_GSK3_1 835 842 PF00069 0.763
MOD_GSK3_1 856 863 PF00069 0.822
MOD_GSK3_1 884 891 PF00069 0.716
MOD_GSK3_1 927 934 PF00069 0.853
MOD_GSK3_1 935 942 PF00069 0.724
MOD_GSK3_1 955 962 PF00069 0.515
MOD_GSK3_1 965 972 PF00069 0.697
MOD_GSK3_1 978 985 PF00069 0.634
MOD_LATS_1 584 590 PF00433 0.883
MOD_N-GLC_1 123 128 PF02516 0.859
MOD_N-GLC_1 169 174 PF02516 0.871
MOD_N-GLC_1 204 209 PF02516 0.882
MOD_N-GLC_1 246 251 PF02516 0.794
MOD_N-GLC_1 486 491 PF02516 0.866
MOD_N-GLC_1 851 856 PF02516 0.825
MOD_N-GLC_1 969 974 PF02516 0.873
MOD_N-GLC_1 97 102 PF02516 0.863
MOD_N-GLC_2 300 302 PF02516 0.821
MOD_NEK2_1 139 144 PF00069 0.825
MOD_NEK2_1 237 242 PF00069 0.853
MOD_NEK2_1 560 565 PF00069 0.861
MOD_NEK2_1 668 673 PF00069 0.871
MOD_NEK2_1 680 685 PF00069 0.639
MOD_NEK2_1 687 692 PF00069 0.404
MOD_NEK2_1 751 756 PF00069 0.688
MOD_NEK2_1 758 763 PF00069 0.581
MOD_NEK2_1 856 861 PF00069 0.825
MOD_PIKK_1 204 210 PF00454 0.881
MOD_PIKK_1 473 479 PF00454 0.846
MOD_PIKK_1 560 566 PF00454 0.862
MOD_PIKK_1 985 991 PF00454 0.798
MOD_PKA_1 251 257 PF00069 0.778
MOD_PKA_2 213 219 PF00069 0.876
MOD_PKA_2 227 233 PF00069 0.615
MOD_PKA_2 251 257 PF00069 0.778
MOD_PKA_2 285 291 PF00069 0.787
MOD_PKA_2 383 389 PF00069 0.818
MOD_PKA_2 402 408 PF00069 0.524
MOD_PKA_2 470 476 PF00069 0.842
MOD_PKA_2 585 591 PF00069 0.882
MOD_PKA_2 624 630 PF00069 0.878
MOD_PKA_2 680 686 PF00069 0.839
MOD_PKA_2 698 704 PF00069 0.382
MOD_PKA_2 741 747 PF00069 0.659
MOD_PKA_2 758 764 PF00069 0.410
MOD_PKA_2 768 774 PF00069 0.587
MOD_PKA_2 838 844 PF00069 0.788
MOD_Plk_1 169 175 PF00069 0.869
MOD_Plk_1 18 24 PF00069 0.867
MOD_Plk_1 294 300 PF00069 0.804
MOD_Plk_1 851 857 PF00069 0.826
MOD_Plk_2-3 119 125 PF00069 0.864
MOD_Plk_2-3 5 11 PF00069 0.874
MOD_Plk_2-3 741 747 PF00069 0.659
MOD_Plk_2-3 884 890 PF00069 0.719
MOD_Plk_4 169 175 PF00069 0.869
MOD_Plk_4 251 257 PF00069 0.778
MOD_Plk_4 390 396 PF00069 0.847
MOD_Plk_4 68 74 PF00069 0.785
MOD_Plk_4 741 747 PF00069 0.659
MOD_Plk_4 788 794 PF00069 0.745
MOD_ProDKin_1 182 188 PF00069 0.865
MOD_ProDKin_1 329 335 PF00069 0.830
MOD_ProDKin_1 354 360 PF00069 0.853
MOD_ProDKin_1 43 49 PF00069 0.860
MOD_ProDKin_1 440 446 PF00069 0.828
MOD_ProDKin_1 519 525 PF00069 0.841
MOD_ProDKin_1 526 532 PF00069 0.742
MOD_ProDKin_1 563 569 PF00069 0.862
MOD_ProDKin_1 574 580 PF00069 0.685
MOD_ProDKin_1 599 605 PF00069 0.871
MOD_ProDKin_1 634 640 PF00069 0.883
MOD_ProDKin_1 655 661 PF00069 0.861
MOD_ProDKin_1 925 931 PF00069 0.849
MOD_ProDKin_1 932 938 PF00069 0.741
MOD_ProDKin_1 939 945 PF00069 0.607
MOD_ProDKin_1 963 969 PF00069 0.878
MOD_ProDKin_1 982 988 PF00069 0.500
MOD_SUMO_rev_2 277 285 PF00179 0.747
MOD_SUMO_rev_2 499 504 PF00179 0.867
MOD_SUMO_rev_2 988 995 PF00179 0.773
TRG_DiLeu_BaEn_1 711 716 PF01217 0.719
TRG_DiLeu_BaEn_1 741 746 PF01217 0.651
TRG_DiLeu_BaEn_1 747 752 PF01217 0.574
TRG_DiLeu_BaLyEn_6 448 453 PF01217 0.849
TRG_DiLeu_BaLyEn_6 520 525 PF01217 0.842
TRG_DiLeu_LyEn_5 747 752 PF01217 0.679
TRG_ENDOCYTIC_2 195 198 PF00928 0.855
TRG_ENDOCYTIC_2 515 518 PF00928 0.860
TRG_ENDOCYTIC_2 778 781 PF00928 0.769
TRG_ENDOCYTIC_2 877 880 PF00928 0.750
TRG_ER_diArg_1 1009 1012 PF00400 0.645
TRG_ER_diArg_1 264 267 PF00400 0.772
TRG_ER_diArg_1 644 647 PF00400 0.884
TRG_ER_diArg_1 755 758 PF00400 0.691
TRG_ER_diArg_1 780 783 PF00400 0.776
TRG_ER_diArg_1 802 805 PF00400 0.740
TRG_ER_diArg_1 998 1000 PF00400 0.765
TRG_NLS_MonoExtN_4 777 783 PF00514 0.771
TRG_Pf-PMV_PEXEL_1 451 455 PF00026 0.842
TRG_Pf-PMV_PEXEL_1 706 711 PF00026 0.675

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS