BZIP domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H9Y4_LEIBR

TriTrypDb:

LbrM.19.0580 , LBRM2903_190010500

Length:

953

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H9Y4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H9Y4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	37	41	PF00656	0.604
CLV_C14_Caspase3-7	437	441	PF00656	0.848
CLV_C14_Caspase3-7	567	571	PF00656	0.599
CLV_NRD_NRD_1	15	17	PF00675	0.838
CLV_NRD_NRD_1	150	152	PF00675	0.873
CLV_NRD_NRD_1	204	206	PF00675	0.609
CLV_NRD_NRD_1	54	56	PF00675	0.848
CLV_NRD_NRD_1	660	662	PF00675	0.618
CLV_NRD_NRD_1	722	724	PF00675	0.852
CLV_NRD_NRD_1	773	775	PF00675	0.711
CLV_NRD_NRD_1	888	890	PF00675	0.727
CLV_PCSK_KEX2_1	15	17	PF00082	0.838
CLV_PCSK_KEX2_1	150	152	PF00082	0.873
CLV_PCSK_KEX2_1	54	56	PF00082	0.854
CLV_PCSK_KEX2_1	660	662	PF00082	0.618
CLV_PCSK_KEX2_1	772	774	PF00082	0.554
CLV_PCSK_KEX2_1	888	890	PF00082	0.603
CLV_PCSK_PC1ET2_1	54	56	PF00082	0.854
CLV_PCSK_SKI1_1	154	158	PF00082	0.616
CLV_PCSK_SKI1_1	192	196	PF00082	0.861
CLV_PCSK_SKI1_1	280	284	PF00082	0.793
CLV_PCSK_SKI1_1	415	419	PF00082	0.727
CLV_PCSK_SKI1_1	427	431	PF00082	0.587
CLV_PCSK_SKI1_1	543	547	PF00082	0.605
CLV_PCSK_SKI1_1	809	813	PF00082	0.640
CLV_PCSK_SKI1_1	816	820	PF00082	0.462
CLV_PCSK_SKI1_1	945	949	PF00082	0.739
DEG_APCC_DBOX_1	426	434	PF00400	0.820
DEG_Nend_UBRbox_2	1	3	PF02207	0.864
DEG_SCF_FBW7_1	737	743	PF00400	0.759
DEG_SPOP_SBC_1	281	285	PF00917	0.563
DEG_SPOP_SBC_1	624	628	PF00917	0.807
DOC_CKS1_1	717	722	PF01111	0.846
DOC_CKS1_1	726	731	PF01111	0.706
DOC_CKS1_1	737	742	PF01111	0.527
DOC_CYCLIN_yCln2_LP_2	313	319	PF00134	0.560
DOC_CYCLIN_yCln2_LP_2	500	506	PF00134	0.797
DOC_MAPK_gen_1	591	601	PF00069	0.604
DOC_MAPK_gen_1	813	823	PF00069	0.601
DOC_MAPK_MEF2A_6	543	552	PF00069	0.859
DOC_PP2B_LxvP_1	622	625	PF13499	0.813
DOC_PP2B_LxvP_1	750	753	PF13499	0.731
DOC_PP4_FxxP_1	490	493	PF00568	0.684
DOC_PP4_FxxP_1	792	795	PF00568	0.578
DOC_PP4_MxPP_1	585	588	PF00568	0.590
DOC_USP7_MATH_1	181	185	PF00917	0.851
DOC_USP7_MATH_1	217	221	PF00917	0.857
DOC_USP7_MATH_1	263	267	PF00917	0.576
DOC_USP7_MATH_1	281	285	PF00917	0.678
DOC_USP7_MATH_1	329	333	PF00917	0.661
DOC_USP7_MATH_1	339	343	PF00917	0.741
DOC_USP7_MATH_1	34	38	PF00917	0.862
DOC_USP7_MATH_1	355	359	PF00917	0.634
DOC_USP7_MATH_1	406	410	PF00917	0.557
DOC_USP7_MATH_1	493	497	PF00917	0.572
DOC_USP7_MATH_1	572	576	PF00917	0.740
DOC_USP7_MATH_1	639	643	PF00917	0.648
DOC_USP7_MATH_1	69	73	PF00917	0.585
DOC_USP7_MATH_1	704	708	PF00917	0.754
DOC_USP7_MATH_1	740	744	PF00917	0.669
DOC_USP7_MATH_1	946	950	PF00917	0.610
DOC_USP7_MATH_2	558	564	PF00917	0.856
DOC_WW_Pin1_4	208	213	PF00397	0.859
DOC_WW_Pin1_4	227	232	PF00397	0.530
DOC_WW_Pin1_4	241	246	PF00397	0.629
DOC_WW_Pin1_4	253	258	PF00397	0.661
DOC_WW_Pin1_4	327	332	PF00397	0.555
DOC_WW_Pin1_4	351	356	PF00397	0.800
DOC_WW_Pin1_4	529	534	PF00397	0.838
DOC_WW_Pin1_4	536	541	PF00397	0.732
DOC_WW_Pin1_4	544	549	PF00397	0.606
DOC_WW_Pin1_4	554	559	PF00397	0.588
DOC_WW_Pin1_4	574	579	PF00397	0.502
DOC_WW_Pin1_4	620	625	PF00397	0.746
DOC_WW_Pin1_4	626	631	PF00397	0.806
DOC_WW_Pin1_4	659	664	PF00397	0.774
DOC_WW_Pin1_4	695	700	PF00397	0.840
DOC_WW_Pin1_4	716	721	PF00397	0.846
DOC_WW_Pin1_4	725	730	PF00397	0.702
DOC_WW_Pin1_4	736	741	PF00397	0.530
DOC_WW_Pin1_4	764	769	PF00397	0.721
DOC_WW_Pin1_4	872	877	PF00397	0.749
LIG_14-3-3_CanoR_1	15	19	PF00244	0.666
LIG_14-3-3_CanoR_1	205	209	PF00244	0.616
LIG_14-3-3_CanoR_1	35	43	PF00244	0.530
LIG_14-3-3_CanoR_1	415	422	PF00244	0.719
LIG_14-3-3_CanoR_1	5	13	PF00244	0.856
LIG_14-3-3_CanoR_1	516	524	PF00244	0.827
LIG_14-3-3_CanoR_1	543	548	PF00244	0.603
LIG_14-3-3_CanoR_1	591	601	PF00244	0.857
LIG_14-3-3_CanoR_1	747	753	PF00244	0.768
LIG_14-3-3_CanoR_1	888	896	PF00244	0.696
LIG_BRCT_BRCA1_1	183	187	PF00533	0.855
LIG_BRCT_BRCA1_1	514	518	PF00533	0.832
LIG_BRCT_BRCA1_1	525	529	PF00533	0.644
LIG_BRCT_BRCA1_1	96	100	PF00533	0.719
LIG_CtBP_PxDLS_1	305	309	PF00389	0.562
LIG_CtBP_PxDLS_1	565	569	PF00389	0.842
LIG_deltaCOP1_diTrp_1	413	420	PF00928	0.554
LIG_eIF4E_1	896	902	PF01652	0.612
LIG_EVH1_1	497	501	PF00568	0.560
LIG_EVH1_2	498	502	PF00568	0.560
LIG_FHA_1	281	287	PF00498	0.571
LIG_FHA_1	392	398	PF00498	0.643
LIG_FHA_1	554	560	PF00498	0.601
LIG_FHA_1	717	723	PF00498	0.762
LIG_FHA_1	810	816	PF00498	0.626
LIG_FHA_2	114	120	PF00498	0.757
LIG_FHA_2	181	187	PF00498	0.852
LIG_FHA_2	459	465	PF00498	0.812
LIG_FHA_2	555	561	PF00498	0.856
LIG_FHA_2	591	597	PF00498	0.693
LIG_FHA_2	666	672	PF00498	0.589
LIG_FHA_2	930	936	PF00498	0.391
LIG_FXI_DFP_1	479	483	PF00024	0.804
LIG_Integrin_isoDGR_2	870	872	PF01839	0.679
LIG_LIR_Apic_2	489	493	PF02991	0.685
LIG_LIR_Apic_2	791	795	PF02991	0.571
LIG_LIR_Gen_1	267	278	PF02991	0.669
LIG_LIR_Gen_1	577	587	PF02991	0.593
LIG_LIR_Gen_1	893	902	PF02991	0.631
LIG_LIR_Nem_3	267	273	PF02991	0.666
LIG_LIR_Nem_3	413	417	PF02991	0.645
LIG_LIR_Nem_3	577	582	PF02991	0.590
LIG_LIR_Nem_3	615	620	PF02991	0.793
LIG_LIR_Nem_3	847	853	PF02991	0.604
LIG_LIR_Nem_3	893	899	PF02991	0.650
LIG_NRP_CendR_1	951	953	PF00754	0.836
LIG_Pex14_2	482	486	PF04695	0.804
LIG_Rb_pABgroove_1	829	837	PF01858	0.626
LIG_SH2_CRK	579	583	PF00017	0.856
LIG_SH2_CRK	919	923	PF00017	0.604
LIG_SH2_GRB2like	112	115	PF00017	0.605
LIG_SH2_SRC	896	899	PF00017	0.630
LIG_SH2_STAT5	579	582	PF00017	0.853
LIG_SH2_STAT5	738	741	PF00017	0.861
LIG_SH2_STAT5	854	857	PF00017	0.588
LIG_SH3_1	734	740	PF00018	0.861
LIG_SH3_2	589	594	PF14604	0.688
LIG_SH3_3	156	162	PF00018	0.861
LIG_SH3_3	209	215	PF00018	0.849
LIG_SH3_3	216	222	PF00018	0.738
LIG_SH3_3	254	260	PF00018	0.843
LIG_SH3_3	273	279	PF00018	0.486
LIG_SH3_3	335	341	PF00018	0.684
LIG_SH3_3	495	501	PF00018	0.565
LIG_SH3_3	547	553	PF00018	0.790
LIG_SH3_3	586	592	PF00018	0.815
LIG_SH3_3	714	720	PF00018	0.848
LIG_SH3_3	734	740	PF00018	0.530
LIG_SH3_3	742	748	PF00018	0.708
LIG_SH3_3	82	88	PF00018	0.856
LIG_SUMO_SIM_anti_2	932	941	PF11976	0.619
LIG_TRFH_1	620	624	PF08558	0.825
LIG_UBA3_1	864	868	PF00899	0.661
LIG_UBA3_1	939	948	PF00899	0.657
LIG_WRC_WIRS_1	356	361	PF05994	0.712
LIG_WRC_WIRS_1	820	825	PF05994	0.586
LIG_WW_2	498	501	PF00397	0.553
LIG_WW_3	163	167	PF00397	0.854
LIG_WW_3	337	341	PF00397	0.585
LIG_WW_3	552	556	PF00397	0.599
MOD_CDK_SPK_2	243	248	PF00069	0.854
MOD_CDK_SPK_2	659	664	PF00069	0.859
MOD_CDK_SPxxK_3	231	238	PF00069	0.743
MOD_CDK_SPxxK_3	241	248	PF00069	0.645
MOD_CDK_SPxxK_3	536	543	PF00069	0.852
MOD_CDK_SPxxK_3	544	551	PF00069	0.726
MOD_CDK_SPxxK_3	716	723	PF00069	0.848
MOD_CK1_1	105	111	PF00069	0.752
MOD_CK1_1	113	119	PF00069	0.825
MOD_CK1_1	14	20	PF00069	0.832
MOD_CK1_1	198	204	PF00069	0.852
MOD_CK1_1	230	236	PF00069	0.831
MOD_CK1_1	375	381	PF00069	0.815
MOD_CK1_1	458	464	PF00069	0.559
MOD_CK1_1	532	538	PF00069	0.789
MOD_CK1_1	577	583	PF00069	0.773
MOD_CK1_1	623	629	PF00069	0.582
MOD_CK1_1	662	668	PF00069	0.799
MOD_CK1_1	682	688	PF00069	0.526
MOD_CK1_1	695	701	PF00069	0.793
MOD_CK1_1	707	713	PF00069	0.655
MOD_CK2_1	113	119	PF00069	0.758
MOD_CK2_1	378	384	PF00069	0.815
MOD_CK2_1	385	391	PF00069	0.700
MOD_CK2_1	407	413	PF00069	0.811
MOD_CK2_1	486	492	PF00069	0.823
MOD_CK2_1	554	560	PF00069	0.799
MOD_CK2_1	590	596	PF00069	0.693
MOD_CK2_1	665	671	PF00069	0.590
MOD_GlcNHglycan	102	105	PF01048	0.599
MOD_GlcNHglycan	146	149	PF01048	0.616
MOD_GlcNHglycan	175	178	PF01048	0.744
MOD_GlcNHglycan	198	201	PF01048	0.846
MOD_GlcNHglycan	225	228	PF01048	0.619
MOD_GlcNHglycan	248	251	PF01048	0.782
MOD_GlcNHglycan	26	30	PF01048	0.614
MOD_GlcNHglycan	308	311	PF01048	0.712
MOD_GlcNHglycan	327	330	PF01048	0.628
MOD_GlcNHglycan	331	334	PF01048	0.655
MOD_GlcNHglycan	335	338	PF01048	0.668
MOD_GlcNHglycan	341	344	PF01048	0.716
MOD_GlcNHglycan	346	349	PF01048	0.705
MOD_GlcNHglycan	369	372	PF01048	0.819
MOD_GlcNHglycan	448	451	PF01048	0.816
MOD_GlcNHglycan	461	464	PF01048	0.584
MOD_GlcNHglycan	570	573	PF01048	0.705
MOD_GlcNHglycan	633	636	PF01048	0.744
MOD_GlcNHglycan	71	74	PF01048	0.836
MOD_GlcNHglycan	714	717	PF01048	0.849
MOD_GlcNHglycan	730	733	PF01048	0.591
MOD_GlcNHglycan	750	753	PF01048	0.401
MOD_GlcNHglycan	828	831	PF01048	0.451
MOD_GlcNHglycan	92	95	PF01048	0.761
MOD_GSK3_1	108	115	PF00069	0.602
MOD_GSK3_1	173	180	PF00069	0.608
MOD_GSK3_1	195	202	PF00069	0.855
MOD_GSK3_1	204	211	PF00069	0.719
MOD_GSK3_1	223	230	PF00069	0.561
MOD_GSK3_1	317	324	PF00069	0.757
MOD_GSK3_1	325	332	PF00069	0.667
MOD_GSK3_1	351	358	PF00069	0.667
MOD_GSK3_1	378	385	PF00069	0.624
MOD_GSK3_1	455	462	PF00069	0.609
MOD_GSK3_1	482	489	PF00069	0.708
MOD_GSK3_1	512	519	PF00069	0.825
MOD_GSK3_1	523	530	PF00069	0.646
MOD_GSK3_1	532	539	PF00069	0.515
MOD_GSK3_1	560	567	PF00069	0.692
MOD_GSK3_1	568	575	PF00069	0.651
MOD_GSK3_1	577	584	PF00069	0.610
MOD_GSK3_1	590	597	PF00069	0.557
MOD_GSK3_1	620	627	PF00069	0.703
MOD_GSK3_1	688	695	PF00069	0.862
MOD_GSK3_1	704	711	PF00069	0.585
MOD_GSK3_1	712	719	PF00069	0.723
MOD_GSK3_1	724	731	PF00069	0.521
MOD_GSK3_1	732	739	PF00069	0.528
MOD_GSK3_1	90	97	PF00069	0.614
MOD_LATS_1	193	199	PF00433	0.856
MOD_N-GLC_1	113	118	PF02516	0.603
MOD_N-GLC_1	196	201	PF02516	0.851
MOD_N-GLC_1	241	246	PF02516	0.763
MOD_N-GLC_1	44	49	PF02516	0.626
MOD_N-GLC_1	445	450	PF02516	0.835
MOD_N-GLC_1	512	517	PF02516	0.825
MOD_N-GLC_1	809	814	PF02516	0.631
MOD_N-GLC_2	323	325	PF02516	0.646
MOD_NEK2_1	100	105	PF00069	0.852
MOD_NEK2_1	265	270	PF00069	0.777
MOD_NEK2_1	365	370	PF00069	0.769
MOD_NEK2_1	372	377	PF00069	0.697
MOD_NEK2_1	445	450	PF00069	0.629
MOD_NEK2_1	486	491	PF00069	0.821
MOD_NEK2_1	568	573	PF00069	0.596
MOD_NEK2_1	689	694	PF00069	0.862
MOD_NEK2_1	730	735	PF00069	0.746
MOD_NEK2_1	834	839	PF00069	0.533
MOD_NEK2_2	890	895	PF00069	0.694
MOD_PIKK_1	17	23	PF00454	0.820
MOD_PIKK_1	375	381	PF00454	0.718
MOD_PIKK_1	385	391	PF00454	0.602
MOD_PIKK_1	732	738	PF00454	0.859
MOD_PKA_2	14	20	PF00069	0.832
MOD_PKA_2	204	210	PF00069	0.614
MOD_PKA_2	339	345	PF00069	0.667
MOD_PKA_2	34	40	PF00069	0.526
MOD_PKA_2	568	574	PF00069	0.590
MOD_PKA_2	590	596	PF00069	0.743
MOD_PKA_2	69	75	PF00069	0.838
MOD_PKA_2	704	710	PF00069	0.849
MOD_PKA_2	746	752	PF00069	0.791
MOD_PKA_2	756	762	PF00069	0.511
MOD_PKB_1	807	815	PF00069	0.639
MOD_Plk_1	25	31	PF00069	0.603
MOD_Plk_1	595	601	PF00069	0.602
MOD_Plk_2-3	413	419	PF00069	0.807
MOD_Plk_4	122	128	PF00069	0.603
MOD_Plk_4	382	388	PF00069	0.816
MOD_Plk_4	474	480	PF00069	0.566
MOD_Plk_4	816	822	PF00069	0.492
MOD_Plk_4	935	941	PF00069	0.614
MOD_ProDKin_1	208	214	PF00069	0.853
MOD_ProDKin_1	227	233	PF00069	0.531
MOD_ProDKin_1	241	247	PF00069	0.625
MOD_ProDKin_1	253	259	PF00069	0.658
MOD_ProDKin_1	327	333	PF00069	0.555
MOD_ProDKin_1	351	357	PF00069	0.801
MOD_ProDKin_1	529	535	PF00069	0.839
MOD_ProDKin_1	536	542	PF00069	0.734
MOD_ProDKin_1	544	550	PF00069	0.607
MOD_ProDKin_1	554	560	PF00069	0.590
MOD_ProDKin_1	574	580	PF00069	0.504
MOD_ProDKin_1	620	626	PF00069	0.745
MOD_ProDKin_1	659	665	PF00069	0.773
MOD_ProDKin_1	695	701	PF00069	0.841
MOD_ProDKin_1	716	722	PF00069	0.847
MOD_ProDKin_1	725	731	PF00069	0.704
MOD_ProDKin_1	736	742	PF00069	0.529
MOD_ProDKin_1	764	770	PF00069	0.714
MOD_ProDKin_1	872	878	PF00069	0.754
MOD_SUMO_rev_2	458	467	PF00179	0.560
TRG_DiLeu_BaEn_1	382	387	PF01217	0.817
TRG_ENDOCYTIC_2	579	582	PF00928	0.600
TRG_ENDOCYTIC_2	854	857	PF00928	0.588
TRG_ENDOCYTIC_2	896	899	PF00928	0.630
TRG_ENDOCYTIC_2	919	922	PF00928	0.609
TRG_ER_diArg_1	771	774	PF00400	0.714
TRG_ER_diArg_1	888	890	PF00400	0.727
TRG_NES_CRM1_1	920	935	PF08389	0.609
TRG_NLS_MonoExtN_4	54	59	PF00514	0.600
TRG_Pf-PMV_PEXEL_1	16	21	PF00026	0.825

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WVB1	Leishmania donovani	79%	99%
A4HY49	Leishmania infantum	79%	99%
E9ARX8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	99%
Q4QDJ4	Leishmania major	80%	99%