J domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H9W6_LEIBR

TriTrypDb:

LbrM.19.0400 , LBRM2903_190008600

Length:

403

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	10

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Expansion

Sequence features

A4H9W6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H9W6

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	285	289	PF00656	0.339
CLV_C14_Caspase3-7	294	298	PF00656	0.343
CLV_NRD_NRD_1	16	18	PF00675	0.411
CLV_NRD_NRD_1	184	186	PF00675	0.543
CLV_NRD_NRD_1	265	267	PF00675	0.644
CLV_NRD_NRD_1	298	300	PF00675	0.610
CLV_PCSK_KEX2_1	16	18	PF00082	0.411
CLV_PCSK_KEX2_1	183	185	PF00082	0.583
CLV_PCSK_KEX2_1	265	267	PF00082	0.618
CLV_PCSK_KEX2_1	393	395	PF00082	0.484

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3L0	Leptomonas seymouri	72%	100%
A0A0S4IRI9	Bodo saltans	46%	92%
A0A1X0P6G2	Trypanosomatidae	57%	100%
A0A3S5IQZ2	Trypanosoma rangeli	58%	100%
A0A3S7WV59	Leishmania donovani	87%	100%
D0A0B6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	100%
E9AGR1	Leishmania infantum	87%	100%
E9ARW0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4QDL2	Leishmania major	85%	100%
V5C1R6	Trypanosoma cruzi	57%	100%

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