Putative peroxin 13

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Putative peroxin 13

Gene product:

peroxin 13, putative

Species:

Leishmania braziliensis

UniProt:

A4H9W4_LEIBR

TriTrypDb:

LbrM.19.0380 , LBRM2903_190008400

Length:

396

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005778	peroxisomal membrane	6	1
GO:0005794	Golgi apparatus	5	1
GO:0016020	membrane	2	2
GO:0031090	organelle membrane	3	1
GO:0031903	microbody membrane	5	1
GO:0042579	microbody	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0046860	glycosome membrane	7	1
GO:0098588	bounding membrane of organelle	4	1
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4H9W4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H9W4

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	1
GO:0006996	organelle organization	4	1
GO:0007031	peroxisome organization	5	1
GO:0009987	cellular process	1	1
GO:0015919	peroxisomal membrane transport	5	1
GO:0016043	cellular component organization	3	1
GO:0043574	peroxisomal transport	4	1
GO:0046907	intracellular transport	3	1
GO:0051179	localization	1	1
GO:0051234	establishment of localization	2	1
GO:0051641	cellular localization	2	1
GO:0051649	establishment of localization in cell	3	1
GO:0071840	cellular component organization or biogenesis	2	1

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	104	106	PF00675	0.637
CLV_NRD_NRD_1	218	220	PF00675	0.508
CLV_NRD_NRD_1	253	255	PF00675	0.427
CLV_NRD_NRD_1	325	327	PF00675	0.359
CLV_NRD_NRD_1	378	380	PF00675	0.248
CLV_PCSK_FUR_1	102	106	PF00082	0.567
CLV_PCSK_KEX2_1	104	106	PF00082	0.637
CLV_PCSK_KEX2_1	252	254	PF00082	0.428
CLV_PCSK_KEX2_1	325	327	PF00082	0.317
CLV_PCSK_KEX2_1	378	380	PF00082	0.273
CLV_PCSK_SKI1_1	257	261	PF00082	0.475
DEG_APCC_DBOX_1	221	229	PF00400	0.287
DEG_Nend_Nbox_1	1	3	PF02207	0.351
DOC_MAPK_gen_1	125	135	PF00069	0.371
DOC_MAPK_gen_1	219	228	PF00069	0.235
DOC_MAPK_MEF2A_6	222	230	PF00069	0.256
DOC_USP7_MATH_1	200	204	PF00917	0.384
DOC_USP7_MATH_1	303	307	PF00917	0.619
DOC_USP7_MATH_1	318	322	PF00917	0.706
DOC_USP7_MATH_1	358	362	PF00917	0.506
DOC_USP7_MATH_1	367	371	PF00917	0.506
DOC_WW_Pin1_4	371	376	PF00397	0.373
DOC_WW_Pin1_4	80	85	PF00397	0.513
DOC_WW_Pin1_4	95	100	PF00397	0.456
LIG_14-3-3_CanoR_1	219	225	PF00244	0.297
LIG_14-3-3_CanoR_1	254	263	PF00244	0.614
LIG_14-3-3_CanoR_1	311	318	PF00244	0.576
LIG_Actin_WH2_2	135	150	PF00022	0.356
LIG_eIF4E_1	18	24	PF01652	0.440
LIG_FHA_1	138	144	PF00498	0.340
LIG_FHA_1	200	206	PF00498	0.555
LIG_FHA_1	221	227	PF00498	0.204
LIG_FHA_1	244	250	PF00498	0.650
LIG_FHA_2	284	290	PF00498	0.690
LIG_GBD_Chelix_1	135	143	PF00786	0.679
LIG_LIR_Gen_1	384	393	PF02991	0.602
LIG_LIR_Nem_3	261	266	PF02991	0.620
LIG_LIR_Nem_3	384	389	PF02991	0.513
LIG_LIR_Nem_3	75	81	PF02991	0.380
LIG_PDZ_Class_1	391	396	PF00595	0.578
LIG_Pex14_2	154	158	PF04695	0.296
LIG_SH2_CRK	263	267	PF00017	0.625
LIG_SH2_SRC	357	360	PF00017	0.471
LIG_SH2_STAP1	162	166	PF00017	0.286
LIG_SH2_STAP1	272	276	PF00017	0.703
LIG_SH2_STAP1	332	336	PF00017	0.491
LIG_SH2_STAT3	332	335	PF00017	0.513
LIG_SH3_3	88	94	PF00018	0.435
LIG_TRAF2_1	98	101	PF00917	0.445
MOD_CDK_SPxxK_3	371	378	PF00069	0.183
MOD_CDK_SPxxK_3	95	102	PF00069	0.554
MOD_CK1_1	258	264	PF00069	0.516
MOD_CK1_1	275	281	PF00069	0.652
MOD_CK1_1	283	289	PF00069	0.627
MOD_CK1_1	48	54	PF00069	0.582
MOD_CK1_1	66	72	PF00069	0.509
MOD_CK2_1	146	152	PF00069	0.341
MOD_CK2_1	265	271	PF00069	0.547
MOD_CK2_1	276	282	PF00069	0.604
MOD_CK2_1	358	364	PF00069	0.368
MOD_CK2_1	95	101	PF00069	0.505
MOD_CMANNOS	221	224	PF00535	0.408
MOD_Cter_Amidation	376	379	PF01082	0.348
MOD_GlcNHglycan	148	151	PF01048	0.418
MOD_GlcNHglycan	190	193	PF01048	0.495
MOD_GlcNHglycan	20	23	PF01048	0.569
MOD_GlcNHglycan	202	205	PF01048	0.565
MOD_GlcNHglycan	214	217	PF01048	0.476
MOD_GlcNHglycan	257	260	PF01048	0.435
MOD_GlcNHglycan	26	29	PF01048	0.554
MOD_GlcNHglycan	31	34	PF01048	0.555
MOD_GlcNHglycan	318	321	PF01048	0.640
MOD_GlcNHglycan	369	372	PF01048	0.266
MOD_GlcNHglycan	88	91	PF01048	0.549
MOD_GSK3_1	208	215	PF00069	0.631
MOD_GSK3_1	239	246	PF00069	0.559
MOD_GSK3_1	272	279	PF00069	0.574
MOD_GSK3_1	305	312	PF00069	0.681
MOD_GSK3_1	367	374	PF00069	0.266
MOD_GSK3_1	44	51	PF00069	0.474
MOD_N-GLC_1	371	376	PF02516	0.262
MOD_N-GLC_1	95	100	PF02516	0.579
MOD_NEK2_1	24	29	PF00069	0.593
MOD_NEK2_1	64	69	PF00069	0.713
MOD_NEK2_2	272	277	PF00069	0.649
MOD_NEK2_2	342	347	PF00069	0.183
MOD_NEK2_2	45	50	PF00069	0.467
MOD_PIKK_1	170	176	PF00454	0.365
MOD_PIKK_1	194	200	PF00454	0.522
MOD_PIKK_1	265	271	PF00454	0.530
MOD_PIKK_1	310	316	PF00454	0.558
MOD_PIKK_1	56	62	PF00454	0.750
MOD_PKA_2	283	289	PF00069	0.662
MOD_PKA_2	310	316	PF00069	0.555
MOD_Plk_1	272	278	PF00069	0.579
MOD_Plk_4	157	163	PF00069	0.361
MOD_Plk_4	258	264	PF00069	0.432
MOD_Plk_4	305	311	PF00069	0.540
MOD_Plk_4	45	51	PF00069	0.497
MOD_ProDKin_1	371	377	PF00069	0.183
MOD_ProDKin_1	80	86	PF00069	0.656
MOD_ProDKin_1	95	101	PF00069	0.576
TRG_DiLeu_BaLyEn_6	77	82	PF01217	0.475
TRG_ENDOCYTIC_2	161	164	PF00928	0.336
TRG_ENDOCYTIC_2	263	266	PF00928	0.537
TRG_ENDOCYTIC_2	328	331	PF00928	0.371
TRG_ER_diArg_1	102	105	PF00400	0.450
TRG_ER_diArg_1	252	254	PF00400	0.600
TRG_ER_diArg_1	325	327	PF00400	0.505
TRG_NES_CRM1_1	134	145	PF08389	0.404
TRG_NLS_MonoExtN_4	218	223	PF00514	0.339
TRG_Pf-PMV_PEXEL_1	114	119	PF00026	0.568
TRG_PTS1	393	396	PF00515	0.486

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1P9X6	Leptomonas seymouri	68%	93%
A0A0S4J170	Bodo saltans	24%	87%
A0A1X0P6F7	Trypanosomatidae	34%	100%
A0A3S7WV91	Leishmania donovani	78%	95%
A0A422NCY3	Trypanosoma rangeli	31%	100%
D0A0C7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
E9AGQ9	Leishmania infantum	79%	93%
E9ARV8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	93%
Q4QDL4	Leishmania major	78%	100%