Histone H2B

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Histone H2B

Gene product:

histone H2B

Species:

Leishmania braziliensis

UniProt:

A4H9W0_LEIBR

TriTrypDb:

LbrM.19.0340 , LBRM2903_190008300

Length:

182

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 40

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 16

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Show entries

Cellular components
Term	Name	Level	Count
GO:0000786	nucleosome	3	9
GO:0005634	nucleus	5	9
GO:0032991	protein-containing complex	1	9
GO:0032993	protein-DNA complex	2	9
GO:0043226	organelle	2	9
GO:0043227	membrane-bounded organelle	3	9
GO:0043229	intracellular organelle	3	9
GO:0043231	intracellular membrane-bounded organelle	4	9
GO:0044815	DNA packaging complex	2	9
GO:0110165	cellular anatomical entity	1	9

Previous1Next

Expansion

Sequence features

A4H9W0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H9W0

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006325	chromatin organization	4	1
GO:0006334	nucleosome assembly	7	1
GO:0006338	chromatin remodeling	5	1
GO:0009987	cellular process	1	1
GO:0016043	cellular component organization	3	1
GO:0022607	cellular component assembly	4	1
GO:0034728	nucleosome organization	6	1
GO:0043933	protein-containing complex organization	4	1
GO:0065003	protein-containing complex assembly	5	1
GO:0065004	protein-DNA complex assembly	6	1

Previous1 2Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	9
GO:0003677	DNA binding	4	9
GO:0005198	structural molecule activity	1	9
GO:0005488	binding	1	9
GO:0005515	protein binding	2	9
GO:0030527	structural constituent of chromatin	2	9
GO:0046982	protein heterodimerization activity	4	9
GO:0046983	protein dimerization activity	3	9
GO:0097159	organic cyclic compound binding	2	9
GO:1901363	heterocyclic compound binding	2	9

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	79	81	PF00675	0.833
CLV_NRD_NRD_1	89	91	PF00675	0.386
CLV_PCSK_KEX2_1	145	147	PF00082	0.385
CLV_PCSK_KEX2_1	93	95	PF00082	0.414
CLV_PCSK_PC1ET2_1	145	147	PF00082	0.385
CLV_PCSK_PC1ET2_1	93	95	PF00082	0.451
CLV_PCSK_PC7_1	141	147	PF00082	0.385
CLV_PCSK_SKI1_1	102	106	PF00082	0.472
CLV_PCSK_SKI1_1	158	162	PF00082	0.509
DEG_SCF_FBW7_1	1	6	PF00400	0.500

Previous1 2 3 4 5…8Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H7I6	Leishmania donovani	41%	100%
A4H9W1	Leishmania braziliensis	99%	100%
A4HG62	Leishmania braziliensis	43%	100%
A4HY42	Leishmania infantum	75%	100%
A4I394	Leishmania infantum	41%	100%
E9AZI2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	100%
Q4Q8P9	Leishmania major	43%	100%

Previous1Next