SNF2/RAD54 related DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

SNF2/RAD54 related DNA helicase

Species:

Leishmania braziliensis

UniProt:

A4H9V3_LEIBR

TriTrypDb:

LbrM.19.0270 , LBRM2903_190007500

Length:

958

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005657	replication fork	2	1
GO:0043596	nuclear replication fork	3	1
GO:0110165	cellular anatomical entity	1	3
GO:0016020	membrane	2	2

Expansion

Sequence features

A4H9V3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H9V3

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006259	DNA metabolic process	4	1
GO:0006275	regulation of DNA replication	6	1
GO:0006281	DNA repair	5	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0008152	metabolic process	1	1
GO:0008156	negative regulation of DNA replication	7	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0009987	cellular process	1	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0031297	replication fork processing	6	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031324	negative regulation of cellular metabolic process	5	1
GO:0033554	cellular response to stress	3	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0045005	DNA-templated DNA replication maintenance of fidelity	5	1
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	6	1
GO:0046483	heterocycle metabolic process	3	1
GO:0048478	obsolete replication fork protection	6	1
GO:0048519	negative regulation of biological process	3	1
GO:0048523	negative regulation of cellular process	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0050896	response to stimulus	1	1
GO:0051052	regulation of DNA metabolic process	5	1
GO:0051053	negative regulation of DNA metabolic process	6	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051172	negative regulation of nitrogen compound metabolic process	5	1
GO:0051716	cellular response to stimulus	2	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0071704	organic substance metabolic process	2	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0090304	nucleic acid metabolic process	4	1
GO:0090329	regulation of DNA-templated DNA replication	7	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:2000104	negative regulation of DNA-templated DNA replication	8	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003676	nucleic acid binding	3	11
GO:0003824	catalytic activity	1	11
GO:0004386	helicase activity	2	8
GO:0004518	nuclease activity	4	11
GO:0004519	endonuclease activity	5	11
GO:0005488	binding	1	11
GO:0005524	ATP binding	5	11
GO:0008094	ATP-dependent activity, acting on DNA	2	11
GO:0016491	oxidoreductase activity	2	10
GO:0016787	hydrolase activity	2	11
GO:0016788	hydrolase activity, acting on ester bonds	3	11
GO:0017076	purine nucleotide binding	4	11
GO:0030554	adenyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032559	adenyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0051213	dioxygenase activity	3	10
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:0140097	catalytic activity, acting on DNA	3	11
GO:0140640	catalytic activity, acting on a nucleic acid	2	11
GO:0140657	ATP-dependent activity	1	11
GO:0140658	ATP-dependent chromatin remodeler activity	3	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11
GO:0004520	DNA endonuclease activity	5	1
GO:0004536	DNA nuclease activity	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	310	314	PF00656	0.458
CLV_C14_Caspase3-7	503	507	PF00656	0.382
CLV_C14_Caspase3-7	679	683	PF00656	0.271
CLV_C14_Caspase3-7	790	794	PF00656	0.325
CLV_NRD_NRD_1	180	182	PF00675	0.593
CLV_NRD_NRD_1	384	386	PF00675	0.379
CLV_NRD_NRD_1	399	401	PF00675	0.156
CLV_NRD_NRD_1	409	411	PF00675	0.238
CLV_NRD_NRD_1	429	431	PF00675	0.576
CLV_NRD_NRD_1	485	487	PF00675	0.251
CLV_NRD_NRD_1	692	694	PF00675	0.423
CLV_NRD_NRD_1	720	722	PF00675	0.584
CLV_NRD_NRD_1	739	741	PF00675	0.579
CLV_NRD_NRD_1	809	811	PF00675	0.434
CLV_NRD_NRD_1	816	818	PF00675	0.367
CLV_NRD_NRD_1	847	849	PF00675	0.474
CLV_NRD_NRD_1	955	957	PF00675	0.542
CLV_PCSK_FUR_1	427	431	PF00082	0.459
CLV_PCSK_KEX2_1	180	182	PF00082	0.583
CLV_PCSK_KEX2_1	325	327	PF00082	0.231
CLV_PCSK_KEX2_1	384	386	PF00082	0.377
CLV_PCSK_KEX2_1	399	401	PF00082	0.163
CLV_PCSK_KEX2_1	429	431	PF00082	0.640
CLV_PCSK_KEX2_1	692	694	PF00082	0.421
CLV_PCSK_KEX2_1	719	721	PF00082	0.656
CLV_PCSK_KEX2_1	739	741	PF00082	0.525
CLV_PCSK_KEX2_1	809	811	PF00082	0.407
CLV_PCSK_KEX2_1	816	818	PF00082	0.394
CLV_PCSK_KEX2_1	847	849	PF00082	0.547
CLV_PCSK_KEX2_1	918	920	PF00082	0.521
CLV_PCSK_KEX2_1	955	957	PF00082	0.522
CLV_PCSK_PC1ET2_1	325	327	PF00082	0.261
CLV_PCSK_PC1ET2_1	918	920	PF00082	0.552
CLV_PCSK_PC1ET2_1	955	957	PF00082	0.538
CLV_PCSK_SKI1_1	118	122	PF00082	0.386
CLV_PCSK_SKI1_1	181	185	PF00082	0.614
CLV_PCSK_SKI1_1	192	196	PF00082	0.237
CLV_PCSK_SKI1_1	200	204	PF00082	0.242
CLV_PCSK_SKI1_1	273	277	PF00082	0.323
CLV_PCSK_SKI1_1	399	403	PF00082	0.270
CLV_PCSK_SKI1_1	464	468	PF00082	0.312
CLV_PCSK_SKI1_1	924	928	PF00082	0.593
CLV_Separin_Metazoa	407	411	PF03568	0.487
DEG_APCC_DBOX_1	384	392	PF00400	0.384
DEG_APCC_KENBOX_2	444	448	PF00400	0.284
DEG_Nend_UBRbox_2	1	3	PF02207	0.470
DOC_ANK_TNKS_1	849	856	PF00023	0.416
DOC_CDC14_PxL_1	172	180	PF14671	0.436
DOC_CDC14_PxL_1	222	230	PF14671	0.487
DOC_CYCLIN_yCln2_LP_2	121	127	PF00134	0.473
DOC_CYCLIN_yCln2_LP_2	741	747	PF00134	0.358
DOC_MAPK_DCC_7	52	61	PF00069	0.436
DOC_MAPK_gen_1	325	333	PF00069	0.431
DOC_MAPK_gen_1	399	408	PF00069	0.438
DOC_MAPK_gen_1	410	418	PF00069	0.470
DOC_MAPK_gen_1	483	492	PF00069	0.416
DOC_MAPK_gen_1	50	58	PF00069	0.471
DOC_MAPK_gen_1	719	730	PF00069	0.645
DOC_MAPK_gen_1	918	927	PF00069	0.629
DOC_MAPK_HePTP_8	49	61	PF00069	0.433
DOC_MAPK_MEF2A_6	370	379	PF00069	0.382
DOC_MAPK_MEF2A_6	50	58	PF00069	0.456
DOC_MAPK_MEF2A_6	74	82	PF00069	0.315
DOC_MAPK_MEF2A_6	921	929	PF00069	0.440
DOC_PP1_RVXF_1	198	204	PF00149	0.333
DOC_PP1_RVXF_1	234	240	PF00149	0.487
DOC_PP1_RVXF_1	737	744	PF00149	0.455
DOC_PP1_RVXF_1	801	807	PF00149	0.514
DOC_PP2B_LxvP_1	406	409	PF13499	0.480
DOC_PP4_FxxP_1	147	150	PF00568	0.412
DOC_USP7_MATH_1	409	413	PF00917	0.533
DOC_USP7_MATH_1	590	594	PF00917	0.588
DOC_USP7_MATH_1	60	64	PF00917	0.403
DOC_USP7_MATH_1	713	717	PF00917	0.525
DOC_USP7_MATH_1	789	793	PF00917	0.315
DOC_WW_Pin1_4	324	329	PF00397	0.463
DOC_WW_Pin1_4	333	338	PF00397	0.419
DOC_WW_Pin1_4	371	376	PF00397	0.469
DOC_WW_Pin1_4	61	66	PF00397	0.507
DOC_WW_Pin1_4	616	621	PF00397	0.554
DOC_WW_Pin1_4	685	690	PF00397	0.565
LIG_14-3-3_CanoR_1	180	184	PF00244	0.536
LIG_14-3-3_CanoR_1	290	295	PF00244	0.501
LIG_14-3-3_CanoR_1	370	374	PF00244	0.411
LIG_14-3-3_CanoR_1	439	445	PF00244	0.468
LIG_14-3-3_CanoR_1	50	55	PF00244	0.480
LIG_14-3-3_CanoR_1	594	599	PF00244	0.665
LIG_14-3-3_CanoR_1	646	650	PF00244	0.507
LIG_14-3-3_CanoR_1	723	729	PF00244	0.559
LIG_14-3-3_CanoR_1	776	782	PF00244	0.328
LIG_14-3-3_CanoR_1	801	807	PF00244	0.457
LIG_14-3-3_CanoR_1	816	820	PF00244	0.311
LIG_14-3-3_CanoR_1	935	939	PF00244	0.562
LIG_Actin_WH2_2	141	158	PF00022	0.442
LIG_Actin_WH2_2	164	182	PF00022	0.306
LIG_BRCT_BRCA1_1	793	797	PF00533	0.425
LIG_CaM_IQ_9	910	926	PF13499	0.354
LIG_Clathr_ClatBox_1	4	8	PF01394	0.499
LIG_CSL_BTD_1	700	703	PF09270	0.403
LIG_deltaCOP1_diTrp_1	671	680	PF00928	0.456
LIG_DLG_GKlike_1	594	602	PF00625	0.620
LIG_eIF4E_1	462	468	PF01652	0.349
LIG_eIF4E_1	747	753	PF01652	0.286
LIG_FHA_1	130	136	PF00498	0.420
LIG_FHA_1	315	321	PF00498	0.438
LIG_FHA_1	44	50	PF00498	0.453
LIG_FHA_1	450	456	PF00498	0.340
LIG_FHA_1	51	57	PF00498	0.553
LIG_FHA_1	594	600	PF00498	0.613
LIG_FHA_1	638	644	PF00498	0.399
LIG_FHA_1	725	731	PF00498	0.540
LIG_FHA_1	87	93	PF00498	0.356
LIG_FHA_1	901	907	PF00498	0.273
LIG_FHA_1	935	941	PF00498	0.599
LIG_FHA_2	164	170	PF00498	0.537
LIG_FHA_2	281	287	PF00498	0.382
LIG_FHA_2	339	345	PF00498	0.409
LIG_FHA_2	677	683	PF00498	0.425
LIG_FHA_2	788	794	PF00498	0.414
LIG_FHA_2	864	870	PF00498	0.281
LIG_FHA_2	911	917	PF00498	0.273
LIG_FHA_2	934	940	PF00498	0.614
LIG_Integrin_RGD_1	501	503	PF01839	0.287
LIG_LIR_Gen_1	291	298	PF02991	0.421
LIG_LIR_Gen_1	313	323	PF02991	0.447
LIG_LIR_Gen_1	340	349	PF02991	0.470
LIG_LIR_Gen_1	374	381	PF02991	0.596
LIG_LIR_Gen_1	460	469	PF02991	0.450
LIG_LIR_Gen_1	578	587	PF02991	0.399
LIG_LIR_Gen_1	651	662	PF02991	0.559
LIG_LIR_Gen_1	671	681	PF02991	0.535
LIG_LIR_Gen_1	777	786	PF02991	0.306
LIG_LIR_Gen_1	85	94	PF02991	0.281
LIG_LIR_Gen_1	939	950	PF02991	0.697
LIG_LIR_Nem_3	22	27	PF02991	0.410
LIG_LIR_Nem_3	223	228	PF02991	0.494
LIG_LIR_Nem_3	291	297	PF02991	0.456
LIG_LIR_Nem_3	313	319	PF02991	0.447
LIG_LIR_Nem_3	340	346	PF02991	0.470
LIG_LIR_Nem_3	374	379	PF02991	0.511
LIG_LIR_Nem_3	446	451	PF02991	0.357
LIG_LIR_Nem_3	460	465	PF02991	0.472
LIG_LIR_Nem_3	578	583	PF02991	0.380
LIG_LIR_Nem_3	651	657	PF02991	0.567
LIG_LIR_Nem_3	671	677	PF02991	0.558
LIG_LIR_Nem_3	777	782	PF02991	0.494
LIG_LIR_Nem_3	85	91	PF02991	0.401
LIG_LIR_Nem_3	939	945	PF02991	0.564
LIG_LYPXL_yS_3	15	18	PF13949	0.321
LIG_LYPXL_yS_3	225	228	PF13949	0.487
LIG_NRBOX	387	393	PF00104	0.399
LIG_PCNA_PIPBox_1	84	93	PF02747	0.253
LIG_Pex14_2	24	28	PF04695	0.383
LIG_Pex14_2	653	657	PF04695	0.467
LIG_Rb_LxCxE_1	293	313	PF01857	0.487
LIG_SH2_CRK	316	320	PF00017	0.446
LIG_SH2_CRK	368	372	PF00017	0.506
LIG_SH2_CRK	462	466	PF00017	0.357
LIG_SH2_CRK	779	783	PF00017	0.301
LIG_SH2_GRB2like	440	443	PF00017	0.435
LIG_SH2_NCK_1	779	783	PF00017	0.301
LIG_SH2_SRC	440	443	PF00017	0.435
LIG_SH2_STAP1	316	320	PF00017	0.438
LIG_SH2_STAP1	440	444	PF00017	0.364
LIG_SH2_STAP1	462	466	PF00017	0.425
LIG_SH2_STAP1	724	728	PF00017	0.566
LIG_SH2_STAP1	88	92	PF00017	0.242
LIG_SH2_STAT5	17	20	PF00017	0.403
LIG_SH2_STAT5	246	249	PF00017	0.533
LIG_SH2_STAT5	316	319	PF00017	0.441
LIG_SH2_STAT5	368	371	PF00017	0.470
LIG_SH2_STAT5	376	379	PF00017	0.470
LIG_SH2_STAT5	567	570	PF00017	0.322
LIG_SH2_STAT5	618	621	PF00017	0.649
LIG_SH2_STAT5	654	657	PF00017	0.459
LIG_SH2_STAT5	742	745	PF00017	0.578
LIG_SH2_STAT5	748	751	PF00017	0.458
LIG_SH2_STAT5	88	91	PF00017	0.237
LIG_SH3_3	139	145	PF00018	0.420
LIG_SH3_3	147	153	PF00018	0.353
LIG_SH3_3	51	57	PF00018	0.445
LIG_SH3_3	603	609	PF00018	0.490
LIG_SH3_3	712	718	PF00018	0.561
LIG_SH3_3	869	875	PF00018	0.393
LIG_SH3_3	922	928	PF00018	0.633
LIG_SUMO_SIM_anti_2	33	40	PF11976	0.517
LIG_SUMO_SIM_anti_2	463	469	PF11976	0.370
LIG_SUMO_SIM_par_1	102	107	PF11976	0.285
LIG_SUMO_SIM_par_1	273	278	PF11976	0.487
LIG_SUMO_SIM_par_1	63	70	PF11976	0.365
LIG_SUMO_SIM_par_1	74	79	PF11976	0.292
LIG_TRAF2_1	185	188	PF00917	0.290
LIG_TRAF2_1	435	438	PF00917	0.561
LIG_TRAF2_1	928	931	PF00917	0.446
LIG_TRFH_1	779	783	PF08558	0.301
LIG_TYR_ITIM	564	569	PF00017	0.395
LIG_UBA3_1	397	402	PF00899	0.438
LIG_UBA3_1	66	74	PF00899	0.267
LIG_WRC_WIRS_1	276	281	PF05994	0.410
LIG_WRC_WIRS_1	654	659	PF05994	0.357
LIG_WRC_WIRS_1	677	682	PF05994	0.525
LIG_WRC_WIRS_1	864	869	PF05994	0.278
MOD_CDK_SPxxK_3	685	692	PF00069	0.531
MOD_CK1_1	431	437	PF00069	0.628
MOD_CK1_1	449	455	PF00069	0.336
MOD_CK1_1	585	591	PF00069	0.487
MOD_CK1_1	593	599	PF00069	0.562
MOD_CK1_1	607	613	PF00069	0.607
MOD_CK1_1	637	643	PF00069	0.487
MOD_CK1_1	648	654	PF00069	0.512
MOD_CK1_1	777	783	PF00069	0.318
MOD_CK1_1	791	797	PF00069	0.456
MOD_CK1_1	948	954	PF00069	0.666
MOD_CK2_1	163	169	PF00069	0.384
MOD_CK2_1	249	255	PF00069	0.569
MOD_CK2_1	280	286	PF00069	0.413
MOD_CK2_1	357	363	PF00069	0.494
MOD_CK2_1	432	438	PF00069	0.482
MOD_CK2_1	440	446	PF00069	0.384
MOD_CK2_1	585	591	PF00069	0.532
MOD_CK2_1	655	661	PF00069	0.323
MOD_CK2_1	789	795	PF00069	0.475
MOD_CK2_1	863	869	PF00069	0.283
MOD_CMANNOS	732	735	PF00535	0.503
MOD_Cter_Amidation	323	326	PF01082	0.231
MOD_Cter_Amidation	845	848	PF01082	0.411
MOD_GlcNHglycan	137	140	PF01048	0.467
MOD_GlcNHglycan	232	235	PF01048	0.308
MOD_GlcNHglycan	309	312	PF01048	0.344
MOD_GlcNHglycan	333	336	PF01048	0.267
MOD_GlcNHglycan	430	433	PF01048	0.669
MOD_GlcNHglycan	448	451	PF01048	0.266
MOD_GlcNHglycan	798	801	PF01048	0.439
MOD_GlcNHglycan	810	813	PF01048	0.383
MOD_GSK3_1	157	164	PF00069	0.355
MOD_GSK3_1	348	355	PF00069	0.457
MOD_GSK3_1	387	394	PF00069	0.521
MOD_GSK3_1	428	435	PF00069	0.671
MOD_GSK3_1	578	585	PF00069	0.456
MOD_GSK3_1	590	597	PF00069	0.636
MOD_GSK3_1	621	628	PF00069	0.581
MOD_GSK3_1	648	655	PF00069	0.586
MOD_GSK3_1	676	683	PF00069	0.440
MOD_GSK3_1	763	770	PF00069	0.346
MOD_GSK3_1	787	794	PF00069	0.407
MOD_GSK3_1	833	840	PF00069	0.538
MOD_LATS_1	612	618	PF00433	0.539
MOD_N-GLC_1	307	312	PF02516	0.332
MOD_N-GLC_1	446	451	PF02516	0.503
MOD_N-GLC_1	585	590	PF02516	0.385
MOD_NEK2_1	114	119	PF00069	0.525
MOD_NEK2_1	135	140	PF00069	0.495
MOD_NEK2_1	163	168	PF00069	0.349
MOD_NEK2_1	179	184	PF00069	0.392
MOD_NEK2_1	19	24	PF00069	0.442
MOD_NEK2_1	304	309	PF00069	0.503
MOD_NEK2_1	331	336	PF00069	0.438
MOD_NEK2_1	357	362	PF00069	0.470
MOD_NEK2_1	386	391	PF00069	0.451
MOD_NEK2_1	598	603	PF00069	0.574
MOD_NEK2_1	634	639	PF00069	0.440
MOD_NEK2_1	653	658	PF00069	0.548
MOD_NEK2_1	67	72	PF00069	0.502
MOD_NEK2_1	680	685	PF00069	0.478
MOD_NEK2_1	774	779	PF00069	0.436
MOD_NEK2_1	796	801	PF00069	0.418
MOD_NEK2_1	815	820	PF00069	0.301
MOD_NEK2_1	837	842	PF00069	0.404
MOD_NEK2_1	86	91	PF00069	0.322
MOD_NEK2_1	933	938	PF00069	0.572
MOD_PIKK_1	570	576	PF00454	0.432
MOD_PIKK_1	598	604	PF00454	0.763
MOD_PIKK_1	910	916	PF00454	0.195
MOD_PKA_2	179	185	PF00069	0.388
MOD_PKA_2	19	25	PF00069	0.462
MOD_PKA_2	352	358	PF00069	0.451
MOD_PKA_2	369	375	PF00069	0.397
MOD_PKA_2	409	415	PF00069	0.571
MOD_PKA_2	428	434	PF00069	0.689
MOD_PKA_2	593	599	PF00069	0.555
MOD_PKA_2	645	651	PF00069	0.540
MOD_PKA_2	722	728	PF00069	0.464
MOD_PKA_2	802	808	PF00069	0.471
MOD_PKA_2	815	821	PF00069	0.340
MOD_PKA_2	934	940	PF00069	0.581
MOD_PKA_2	951	957	PF00069	0.489
MOD_Plk_1	299	305	PF00069	0.477
MOD_Plk_1	386	392	PF00069	0.482
MOD_Plk_1	432	438	PF00069	0.413
MOD_Plk_1	774	780	PF00069	0.485
MOD_Plk_1	894	900	PF00069	0.340
MOD_Plk_2-3	129	135	PF00069	0.417
MOD_Plk_2-3	249	255	PF00069	0.487
MOD_Plk_2-3	264	270	PF00069	0.363
MOD_Plk_4	167	173	PF00069	0.393
MOD_Plk_4	280	286	PF00069	0.428
MOD_Plk_4	352	358	PF00069	0.425
MOD_Plk_4	387	393	PF00069	0.456
MOD_Plk_4	594	600	PF00069	0.553
MOD_Plk_4	676	682	PF00069	0.508
MOD_Plk_4	777	783	PF00069	0.406
MOD_Plk_4	802	808	PF00069	0.437
MOD_ProDKin_1	324	330	PF00069	0.463
MOD_ProDKin_1	333	339	PF00069	0.419
MOD_ProDKin_1	371	377	PF00069	0.469
MOD_ProDKin_1	61	67	PF00069	0.510
MOD_ProDKin_1	616	622	PF00069	0.552
MOD_ProDKin_1	685	691	PF00069	0.561
MOD_SUMO_rev_2	915	920	PF00179	0.351
TRG_DiLeu_BaEn_1	387	392	PF01217	0.438
TRG_DiLeu_BaLyEn_6	418	423	PF01217	0.363
TRG_DiLeu_BaLyEn_6	62	67	PF01217	0.277
TRG_DiLeu_BaLyEn_6	628	633	PF01217	0.483
TRG_DiLeu_BaLyEn_6	748	753	PF01217	0.282
TRG_DiLeu_LyEn_5	223	228	PF01217	0.533
TRG_ENDOCYTIC_2	15	18	PF00928	0.443
TRG_ENDOCYTIC_2	225	228	PF00928	0.568
TRG_ENDOCYTIC_2	316	319	PF00928	0.446
TRG_ENDOCYTIC_2	368	371	PF00928	0.509
TRG_ENDOCYTIC_2	376	379	PF00928	0.487
TRG_ENDOCYTIC_2	462	465	PF00928	0.340
TRG_ENDOCYTIC_2	566	569	PF00928	0.396
TRG_ENDOCYTIC_2	654	657	PF00928	0.541
TRG_ENDOCYTIC_2	779	782	PF00928	0.452
TRG_ENDOCYTIC_2	88	91	PF00928	0.237
TRG_ER_diArg_1	179	181	PF00400	0.561
TRG_ER_diArg_1	289	292	PF00400	0.412
TRG_ER_diArg_1	384	386	PF00400	0.559
TRG_ER_diArg_1	398	400	PF00400	0.369
TRG_ER_diArg_1	49	52	PF00400	0.496
TRG_ER_diArg_1	718	721	PF00400	0.643
TRG_ER_diArg_1	738	740	PF00400	0.467
TRG_ER_diArg_1	801	804	PF00400	0.484
TRG_ER_diArg_1	808	810	PF00400	0.450
TRG_ER_diArg_1	815	817	PF00400	0.392
TRG_NES_CRM1_1	241	255	PF08389	0.494
TRG_NES_CRM1_1	68	81	PF08389	0.491
TRG_NLS_Bipartite_1	399	414	PF00514	0.487
TRG_NLS_MonoExtN_4	409	414	PF00514	0.487
TRG_Pf-PMV_PEXEL_1	200	205	PF00026	0.318
TRG_Pf-PMV_PEXEL_1	399	403	PF00026	0.240

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IHR1	Leptomonas seymouri	55%	99%
A0A1X0NWY2	Trypanosomatidae	41%	97%
A0A3Q8I7U7	Leishmania donovani	83%	100%
A0A3R7RKP1	Trypanosoma rangeli	41%	97%
A4HUR7	Leishmania infantum	83%	100%
D0A7P6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
E9ANF1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4QH75	Leishmania major	81%	100%
V5BRH2	Trypanosoma cruzi	42%	98%