GRIP domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

GRIP domain containing protein, putative

Species:

Leishmania braziliensis

UniProt:

A4H9V1_LEIBR

TriTrypDb:

LbrM.19.0250 , LBRM2903_190007300

Length:

966

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H9V1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H9V1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	184	188	PF00656	0.553
CLV_C14_Caspase3-7	87	91	PF00656	0.658
CLV_NRD_NRD_1	377	379	PF00675	0.606
CLV_NRD_NRD_1	469	471	PF00675	0.599
CLV_NRD_NRD_1	561	563	PF00675	0.628
CLV_NRD_NRD_1	653	655	PF00675	0.602
CLV_NRD_NRD_1	774	776	PF00675	0.602
CLV_NRD_NRD_1	800	802	PF00675	0.690
CLV_PCSK_KEX2_1	377	379	PF00082	0.606
CLV_PCSK_KEX2_1	469	471	PF00082	0.599
CLV_PCSK_KEX2_1	561	563	PF00082	0.628
CLV_PCSK_KEX2_1	653	655	PF00082	0.602
CLV_PCSK_KEX2_1	774	776	PF00082	0.719
CLV_PCSK_SKI1_1	273	277	PF00082	0.660
CLV_PCSK_SKI1_1	629	633	PF00082	0.657
CLV_PCSK_SKI1_1	714	718	PF00082	0.627
CLV_PCSK_SKI1_1	861	865	PF00082	0.668
CLV_Separin_Metazoa	744	748	PF03568	0.689
DEG_APCC_DBOX_1	176	184	PF00400	0.563
DEG_APCC_KENBOX_2	879	883	PF00400	0.723
DEG_Nend_UBRbox_2	1	3	PF02207	0.800
DOC_CYCLIN_RxL_1	341	353	PF00134	0.600
DOC_MAPK_gen_1	44	51	PF00069	0.680
DOC_MAPK_gen_1	653	659	PF00069	0.597
DOC_MAPK_gen_1	950	957	PF00069	0.433
DOC_MAPK_MEF2A_6	16	23	PF00069	0.584
DOC_MAPK_MEF2A_6	658	666	PF00069	0.590
DOC_MAPK_MEF2A_6	699	706	PF00069	0.643
DOC_MAPK_MEF2A_6	907	916	PF00069	0.678
DOC_MAPK_RevD_3	615	629	PF00069	0.565
DOC_PP4_FxxP_1	867	870	PF00568	0.668
DOC_USP7_MATH_1	110	114	PF00917	0.566
DOC_USP7_MATH_1	292	296	PF00917	0.812
DOC_USP7_MATH_1	740	744	PF00917	0.632
DOC_USP7_MATH_1	821	825	PF00917	0.756
DOC_USP7_MATH_1	837	841	PF00917	0.598
DOC_USP7_UBL2_3	352	356	PF12436	0.580
DOC_USP7_UBL2_3	444	448	PF12436	0.692
DOC_USP7_UBL2_3	536	540	PF12436	0.786
DOC_USP7_UBL2_3	58	62	PF12436	0.681
DOC_USP7_UBL2_3	628	632	PF12436	0.676
DOC_USP7_UBL2_3	880	884	PF12436	0.530
DOC_WW_Pin1_4	91	96	PF00397	0.759
LIG_14-3-3_CanoR_1	157	165	PF00244	0.580
LIG_14-3-3_CanoR_1	301	305	PF00244	0.781
LIG_14-3-3_CanoR_1	365	370	PF00244	0.535
LIG_14-3-3_CanoR_1	457	462	PF00244	0.585
LIG_14-3-3_CanoR_1	549	554	PF00244	0.634
LIG_14-3-3_CanoR_1	658	666	PF00244	0.620
LIG_Actin_WH2_2	642	660	PF00022	0.586
LIG_Actin_WH2_2	734	751	PF00022	0.711
LIG_APCC_ABBA_1	330	335	PF00400	0.714
LIG_DLG_GKlike_1	653	661	PF00625	0.595
LIG_FHA_1	139	145	PF00498	0.567
LIG_FHA_1	417	423	PF00498	0.608
LIG_FHA_1	46	52	PF00498	0.678
LIG_FHA_1	509	515	PF00498	0.644
LIG_FHA_1	601	607	PF00498	0.610
LIG_FHA_1	92	98	PF00498	0.576
LIG_FHA_2	134	140	PF00498	0.551
LIG_FHA_2	235	241	PF00498	0.575
LIG_FHA_2	26	32	PF00498	0.673
LIG_FHA_2	300	306	PF00498	0.720
LIG_FHA_2	54	60	PF00498	0.680
LIG_FHA_2	642	648	PF00498	0.572
LIG_FHA_2	683	689	PF00498	0.616
LIG_FHA_2	87	93	PF00498	0.573
LIG_FHA_2	871	877	PF00498	0.643
LIG_FHA_2	941	947	PF00498	0.549
LIG_GBD_Chelix_1	32	40	PF00786	0.690
LIG_LIR_Apic_2	866	870	PF02991	0.671
LIG_LIR_Gen_1	45	51	PF02991	0.681
LIG_LIR_Gen_1	638	645	PF02991	0.571
LIG_LIR_Gen_1	80	88	PF02991	0.621
LIG_LIR_Gen_1	862	870	PF02991	0.670
LIG_LIR_Nem_3	45	50	PF02991	0.682
LIG_LIR_Nem_3	638	642	PF02991	0.576
LIG_LIR_Nem_3	80	85	PF02991	0.608
LIG_LIR_Nem_3	862	868	PF02991	0.671
LIG_PCNA_yPIPBox_3	886	900	PF02747	0.688
LIG_REV1ctd_RIR_1	2	11	PF16727	0.783
LIG_RPA_C_Fungi	296	308	PF08784	0.728
LIG_SH2_CRK	328	332	PF00017	0.711
LIG_SH2_CRK	47	51	PF00017	0.681
LIG_SH2_CRK	82	86	PF00017	0.622
LIG_SH2_NCK_1	819	823	PF00017	0.736
LIG_SH2_SRC	819	822	PF00017	0.735
LIG_SH2_STAP1	47	51	PF00017	0.681
LIG_SH2_STAT3	191	194	PF00017	0.565
LIG_SH2_STAT5	47	50	PF00017	0.683
LIG_SH2_STAT5	899	902	PF00017	0.677
LIG_SH2_STAT5	918	921	PF00017	0.549
LIG_SH2_STAT5	926	929	PF00017	0.410
LIG_SH3_1	815	821	PF00018	0.714
LIG_SH3_3	286	292	PF00018	0.855
LIG_SH3_3	815	821	PF00018	0.714
LIG_SH3_3	957	963	PF00018	0.705
LIG_SH3_4	322	329	PF00018	0.704
LIG_SUMO_SIM_anti_2	17	23	PF11976	0.699
LIG_SUMO_SIM_par_1	47	52	PF11976	0.678
LIG_SUMO_SIM_par_1	662	668	PF11976	0.592
LIG_SUMO_SIM_par_1	720	726	PF11976	0.627
LIG_TRAF2_1	15	18	PF00917	0.709
LIG_TRAF2_1	182	185	PF00917	0.674
LIG_TRAF2_1	237	240	PF00917	0.693
LIG_TRAF2_1	368	371	PF00917	0.588
LIG_TRAF2_1	401	404	PF00917	0.602
LIG_TRAF2_1	460	463	PF00917	0.694
LIG_TRAF2_1	493	496	PF00917	0.620
LIG_TRAF2_1	552	555	PF00917	0.735
LIG_TRAF2_1	585	588	PF00917	0.610
LIG_TYR_ITSM	78	85	PF00017	0.602
LIG_UBA3_1	22	27	PF00899	0.567
MOD_CDK_SPxxK_3	91	98	PF00069	0.750
MOD_CK1_1	132	138	PF00069	0.563
MOD_CK1_1	295	301	PF00069	0.739
MOD_CK1_1	311	317	PF00069	0.616
MOD_CK1_1	751	757	PF00069	0.680
MOD_CK1_1	77	83	PF00069	0.652
MOD_CK1_1	86	92	PF00069	0.557
MOD_CK2_1	128	134	PF00069	0.679
MOD_CK2_1	179	185	PF00069	0.675
MOD_CK2_1	220	226	PF00069	0.691
MOD_CK2_1	234	240	PF00069	0.447
MOD_CK2_1	25	31	PF00069	0.555
MOD_CK2_1	299	305	PF00069	0.724
MOD_CK2_1	365	371	PF00069	0.592
MOD_CK2_1	457	463	PF00069	0.598
MOD_CK2_1	53	59	PF00069	0.678
MOD_CK2_1	549	555	PF00069	0.645
MOD_CK2_1	641	647	PF00069	0.583
MOD_CK2_1	781	787	PF00069	0.624
MOD_CK2_1	827	833	PF00069	0.728
MOD_CK2_1	86	92	PF00069	0.607
MOD_CK2_1	940	946	PF00069	0.549
MOD_GlcNHglycan	214	217	PF01048	0.643
MOD_GlcNHglycan	223	226	PF01048	0.581
MOD_GlcNHglycan	294	297	PF01048	0.812
MOD_GlcNHglycan	677	680	PF01048	0.713
MOD_GlcNHglycan	733	736	PF01048	0.712
MOD_GlcNHglycan	835	838	PF01048	0.796
MOD_GlcNHglycan	839	842	PF01048	0.714
MOD_GlcNHglycan	861	864	PF01048	0.666
MOD_GSK3_1	125	132	PF00069	0.662
MOD_GSK3_1	204	211	PF00069	0.572
MOD_GSK3_1	295	302	PF00069	0.852
MOD_GSK3_1	308	315	PF00069	0.608
MOD_GSK3_1	45	52	PF00069	0.679
MOD_GSK3_1	653	660	PF00069	0.532
MOD_GSK3_1	677	684	PF00069	0.740
MOD_GSK3_1	827	834	PF00069	0.831
MOD_N-GLC_1	204	209	PF02516	0.689
MOD_N-GLC_1	263	268	PF02516	0.593
MOD_N-GLC_1	284	289	PF02516	0.863
MOD_N-GLC_1	731	736	PF02516	0.632
MOD_N-GLC_2	117	119	PF02516	0.556
MOD_NEK2_1	208	213	PF00069	0.571
MOD_NEK2_1	284	289	PF00069	0.823
MOD_NEK2_1	436	441	PF00069	0.570
MOD_NEK2_1	49	54	PF00069	0.677
MOD_NEK2_1	528	533	PF00069	0.661
MOD_NEK2_1	620	625	PF00069	0.684
MOD_NEK2_1	657	662	PF00069	0.569
MOD_NEK2_1	706	711	PF00069	0.644
MOD_NEK2_2	720	725	PF00069	0.628
MOD_PIKK_1	138	144	PF00454	0.610
MOD_PIKK_1	156	162	PF00454	0.449
MOD_PIKK_1	208	214	PF00454	0.573
MOD_PIKK_1	229	235	PF00454	0.574
MOD_PIKK_1	313	319	PF00454	0.733
MOD_PIKK_1	35	41	PF00454	0.574
MOD_PIKK_1	657	663	PF00454	0.590
MOD_PIKK_1	831	837	PF00454	0.717
MOD_PKA_1	6	12	PF00069	0.768
MOD_PKA_1	653	659	PF00069	0.597
MOD_PKA_1	774	780	PF00069	0.720
MOD_PKA_2	156	162	PF00069	0.572
MOD_PKA_2	300	306	PF00069	0.779
MOD_PKA_2	64	70	PF00069	0.579
MOD_PKA_2	653	659	PF00069	0.650
MOD_PKA_2	774	780	PF00069	0.720
MOD_PKA_2	781	787	PF00069	0.595
MOD_Plk_1	133	139	PF00069	0.682
MOD_Plk_1	204	210	PF00069	0.689
MOD_Plk_1	263	269	PF00069	0.712
MOD_Plk_1	417	423	PF00069	0.608
MOD_Plk_1	436	442	PF00069	0.348
MOD_Plk_1	509	515	PF00069	0.644
MOD_Plk_1	528	534	PF00069	0.440
MOD_Plk_1	601	607	PF00069	0.616
MOD_Plk_1	620	626	PF00069	0.459
MOD_Plk_1	731	737	PF00069	0.631
MOD_Plk_1	751	757	PF00069	0.447
MOD_Plk_1	77	83	PF00069	0.519
MOD_Plk_2-3	199	205	PF00069	0.692
MOD_Plk_2-3	698	704	PF00069	0.638
MOD_Plk_2-3	781	787	PF00069	0.718
MOD_Plk_4	436	442	PF00069	0.569
MOD_Plk_4	45	51	PF00069	0.681
MOD_Plk_4	528	534	PF00069	0.661
MOD_Plk_4	620	626	PF00069	0.681
MOD_Plk_4	827	833	PF00069	0.786
MOD_Plk_4	940	946	PF00069	0.549
MOD_ProDKin_1	91	97	PF00069	0.754
MOD_SUMO_for_1	15	18	PF00179	0.709
MOD_SUMO_for_1	321	324	PF00179	0.702
MOD_SUMO_for_1	863	866	PF00179	0.675
MOD_SUMO_rev_2	315	323	PF00179	0.715
MOD_SUMO_rev_2	37	45	PF00179	0.685
MOD_SUMO_rev_2	425	431	PF00179	0.584
MOD_SUMO_rev_2	517	523	PF00179	0.642
MOD_SUMO_rev_2	609	615	PF00179	0.584
MOD_SUMO_rev_2	787	795	PF00179	0.583
TRG_DiLeu_BaEn_1	17	22	PF01217	0.701
TRG_DiLeu_BaEn_1	226	231	PF01217	0.579
TRG_DiLeu_BaEn_4	184	190	PF01217	0.555
TRG_DiLeu_BaEn_4	240	246	PF01217	0.569
TRG_DiLeu_BaEn_4	371	377	PF01217	0.588
TRG_DiLeu_BaEn_4	463	469	PF01217	0.698
TRG_DiLeu_BaEn_4	555	561	PF01217	0.729
TRG_ENDOCYTIC_2	47	50	PF00928	0.683
TRG_ENDOCYTIC_2	82	85	PF00928	0.618
TRG_ENDOCYTIC_2	865	868	PF00928	0.675
TRG_ER_diArg_1	376	378	PF00400	0.599
TRG_ER_diArg_1	468	470	PF00400	0.593
TRG_ER_diArg_1	560	562	PF00400	0.621
TRG_ER_diArg_1	652	654	PF00400	0.610
TRG_ER_diArg_1	69	72	PF00400	0.694
TRG_ER_diArg_1	773	775	PF00400	0.609
TRG_ER_diArg_1	815	818	PF00400	0.700
TRG_NES_CRM1_1	142	153	PF08389	0.675
TRG_NES_CRM1_1	265	280	PF08389	0.758
TRG_NLS_MonoExtC_3	627	632	PF00514	0.558
TRG_NLS_MonoExtN_4	628	633	PF00514	0.559
TRG_Pf-PMV_PEXEL_1	236	240	PF00026	0.692
TRG_Pf-PMV_PEXEL_1	62	66	PF00026	0.692
TRG_Pf-PMV_PEXEL_1	920	924	PF00026	0.549

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HUR9	Leishmania infantum	64%	72%