NERD domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H9U6_LEIBR

TriTrypDb:

LbrM.19.0200 , LBRM2903_190006700

Length:

189

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H9U6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H9U6

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	131	133	PF00675	0.430
CLV_NRD_NRD_1	9	11	PF00675	0.446
CLV_NRD_NRD_1	93	95	PF00675	0.398
CLV_PCSK_KEX2_1	131	133	PF00082	0.432
CLV_PCSK_KEX2_1	9	11	PF00082	0.446
CLV_PCSK_KEX2_1	93	95	PF00082	0.398
CLV_PCSK_SKI1_1	32	36	PF00082	0.461
DEG_Nend_Nbox_1	1	3	PF02207	0.571
DOC_MAPK_gen_1	28	37	PF00069	0.445
DOC_MAPK_gen_1	75	82	PF00069	0.541

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAM1	Leptomonas seymouri	67%	100%
A0A3Q8I8Z4	Leishmania donovani	84%	100%
A4HUS4	Leishmania infantum	84%	100%
E9ANF8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4QH68	Leishmania major	87%	100%

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