LeishMANIAdb
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VPS13_C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
VPS13_C domain-containing protein
Gene product:
hypothetical protein (fragment)
Species:
Leishmania braziliensis
UniProt:
A4H9S0_LEIBR
TriTrypDb:
LbrM.18.1720
Length:
256

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Cellular components
Term Name Level Count
GO:0016020 membrane 2 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

A4H9S0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H9S0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 242 246 PF00656 0.730
CLV_PCSK_KEX2_1 206 208 PF00082 0.508
CLV_PCSK_PC1ET2_1 206 208 PF00082 0.508
CLV_PCSK_PC7_1 202 208 PF00082 0.520
DEG_Nend_Nbox_1 1 2 PF02207 0.800
DOC_MAPK_gen_1 2 12 PF00069 0.772
DOC_MAPK_gen_1 206 213 PF00069 0.705
DOC_MAPK_MEF2A_6 5 14 PF00069 0.650
DOC_MAPK_NFAT4_5 5 13 PF00069 0.650
LIG_FHA_2 176 182 PF00498 0.730
LIG_FHA_2 191 197 PF00498 0.571
LIG_FHA_2 240 246 PF00498 0.726
LIG_PTB_Apo_2 219 226 PF02174 0.721
LIG_PTB_Phospho_1 219 225 PF10480 0.719
LIG_SH2_CRK 1 5 PF00017 0.789
LIG_SH2_SRC 225 228 PF00017 0.720
LIG_SH2_STAP1 225 229 PF00017 0.718
LIG_SH2_STAT5 212 215 PF00017 0.700
LIG_TRAF2_1 193 196 PF00917 0.758
LIG_TYR_ITIM 210 215 PF00017 0.704
MOD_CK1_1 175 181 PF00069 0.726
MOD_CK1_1 216 222 PF00069 0.709
MOD_CK1_1 244 250 PF00069 0.732
MOD_CK2_1 173 179 PF00069 0.650
MOD_CK2_1 190 196 PF00069 0.546
MOD_GlcNHglycan 175 178 PF01048 0.520
MOD_GlcNHglycan 218 221 PF01048 0.515
MOD_GlcNHglycan 229 232 PF01048 0.358
MOD_GSK3_1 187 194 PF00069 0.760
MOD_GSK3_1 237 244 PF00069 0.715
MOD_NEK2_1 213 218 PF00069 0.705
MOD_NEK2_1 237 242 PF00069 0.713
MOD_PIKK_1 213 219 PF00454 0.705
MOD_Plk_1 225 231 PF00069 0.713
MOD_Plk_1 244 250 PF00069 0.494
MOD_SUMO_rev_2 175 184 PF00179 0.733
TRG_ENDOCYTIC_2 1 4 PF00928 0.790
TRG_ENDOCYTIC_2 212 215 PF00928 0.700

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS