Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ttaggg binding factor, putative

Species:

Leishmania braziliensis

UniProt:

A4H9N4_LEIBR

TriTrypDb:

LbrM.18.1340 , LBRM2903_180019100

Length:

811

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H9N4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H9N4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	284	288	PF00656	0.532
CLV_C14_Caspase3-7	428	432	PF00656	0.707
CLV_C14_Caspase3-7	480	484	PF00656	0.690
CLV_C14_Caspase3-7	574	578	PF00656	0.573
CLV_C14_Caspase3-7	806	810	PF00656	0.726
CLV_NRD_NRD_1	167	169	PF00675	0.835
CLV_NRD_NRD_1	258	260	PF00675	0.671
CLV_NRD_NRD_1	278	280	PF00675	0.520
CLV_NRD_NRD_1	295	297	PF00675	0.618
CLV_NRD_NRD_1	319	321	PF00675	0.610
CLV_NRD_NRD_1	343	345	PF00675	0.693
CLV_NRD_NRD_1	520	522	PF00675	0.628
CLV_NRD_NRD_1	564	566	PF00675	0.693
CLV_NRD_NRD_1	664	666	PF00675	0.731
CLV_NRD_NRD_1	699	701	PF00675	0.579
CLV_NRD_NRD_1	75	77	PF00675	0.648
CLV_NRD_NRD_1	755	757	PF00675	0.595
CLV_PCSK_KEX2_1	167	169	PF00082	0.835
CLV_PCSK_KEX2_1	258	260	PF00082	0.746
CLV_PCSK_KEX2_1	278	280	PF00082	0.520
CLV_PCSK_KEX2_1	295	297	PF00082	0.621
CLV_PCSK_KEX2_1	319	321	PF00082	0.610
CLV_PCSK_KEX2_1	345	347	PF00082	0.690
CLV_PCSK_KEX2_1	520	522	PF00082	0.628
CLV_PCSK_KEX2_1	564	566	PF00082	0.594
CLV_PCSK_KEX2_1	664	666	PF00082	0.671
CLV_PCSK_KEX2_1	698	700	PF00082	0.601
CLV_PCSK_KEX2_1	75	77	PF00082	0.506
CLV_PCSK_KEX2_1	754	756	PF00082	0.463
CLV_PCSK_PC1ET2_1	345	347	PF00082	0.690
CLV_PCSK_PC7_1	750	756	PF00082	0.446
CLV_PCSK_SKI1_1	127	131	PF00082	0.535
CLV_PCSK_SKI1_1	295	299	PF00082	0.523
CLV_PCSK_SKI1_1	529	533	PF00082	0.708
CLV_PCSK_SKI1_1	669	673	PF00082	0.614
CLV_PCSK_SKI1_1	740	744	PF00082	0.476
CLV_PCSK_SKI1_1	750	754	PF00082	0.384
DEG_SCF_FBW7_1	131	137	PF00400	0.523
DEG_SPOP_SBC_1	160	164	PF00917	0.551
DEG_SPOP_SBC_1	358	362	PF00917	0.722
DEG_SPOP_SBC_1	689	693	PF00917	0.709
DOC_CKS1_1	131	136	PF01111	0.622
DOC_CKS1_1	670	675	PF01111	0.567
DOC_CKS1_1	792	797	PF01111	0.695
DOC_CYCLIN_yCln2_LP_2	122	128	PF00134	0.600
DOC_MAPK_gen_1	737	745	PF00069	0.496
DOC_MAPK_MEF2A_6	178	185	PF00069	0.531
DOC_PP2B_LxvP_1	122	125	PF13499	0.630
DOC_PP2B_LxvP_1	183	186	PF13499	0.529
DOC_PP2B_LxvP_1	554	557	PF13499	0.564
DOC_PP2B_LxvP_1	685	688	PF13499	0.652
DOC_PP2B_LxvP_1	86	89	PF13499	0.528
DOC_USP7_MATH_1	205	209	PF00917	0.541
DOC_USP7_MATH_1	354	358	PF00917	0.678
DOC_USP7_MATH_1	4	8	PF00917	0.583
DOC_USP7_MATH_1	420	424	PF00917	0.543
DOC_USP7_MATH_1	474	478	PF00917	0.542
DOC_USP7_MATH_1	590	594	PF00917	0.616
DOC_USP7_MATH_1	612	616	PF00917	0.433
DOC_USP7_MATH_1	636	640	PF00917	0.796
DOC_USP7_MATH_1	652	656	PF00917	0.537
DOC_USP7_MATH_1	675	679	PF00917	0.706
DOC_USP7_MATH_1	689	693	PF00917	0.726
DOC_USP7_MATH_1	731	735	PF00917	0.478
DOC_USP7_MATH_1	759	763	PF00917	0.524
DOC_WW_Pin1_4	130	135	PF00397	0.628
DOC_WW_Pin1_4	137	142	PF00397	0.570
DOC_WW_Pin1_4	152	157	PF00397	0.544
DOC_WW_Pin1_4	171	176	PF00397	0.668
DOC_WW_Pin1_4	177	182	PF00397	0.691
DOC_WW_Pin1_4	195	200	PF00397	0.529
DOC_WW_Pin1_4	237	242	PF00397	0.714
DOC_WW_Pin1_4	591	596	PF00397	0.621
DOC_WW_Pin1_4	669	674	PF00397	0.567
DOC_WW_Pin1_4	701	706	PF00397	0.549
DOC_WW_Pin1_4	785	790	PF00397	0.705
DOC_WW_Pin1_4	791	796	PF00397	0.639
LIG_14-3-3_CanoR_1	127	132	PF00244	0.524
LIG_14-3-3_CanoR_1	18	25	PF00244	0.684
LIG_14-3-3_CanoR_1	30	34	PF00244	0.531
LIG_14-3-3_CanoR_1	613	621	PF00244	0.454
LIG_14-3-3_CanoR_1	664	671	PF00244	0.675
LIG_14-3-3_CanoR_1	690	697	PF00244	0.562
LIG_14-3-3_CanoR_1	737	746	PF00244	0.496
LIG_14-3-3_CanoR_1	75	85	PF00244	0.453
LIG_14-3-3_CanoR_1	99	104	PF00244	0.444
LIG_Actin_WH2_2	506	522	PF00022	0.586
LIG_APCC_ABBA_1	413	418	PF00400	0.506
LIG_BIR_III_2	483	487	PF00653	0.694
LIG_BRCT_BRCA1_1	200	204	PF00533	0.533
LIG_BRCT_BRCA1_1	721	725	PF00533	0.450
LIG_BRCT_BRCA1_1	93	97	PF00533	0.491
LIG_EH_1	413	417	PF12763	0.496
LIG_EVH1_1	685	689	PF00568	0.557
LIG_FHA_1	117	123	PF00498	0.576
LIG_FHA_1	296	302	PF00498	0.514
LIG_FHA_1	389	395	PF00498	0.713
LIG_FHA_1	436	442	PF00498	0.640
LIG_FHA_1	451	457	PF00498	0.559
LIG_FHA_1	526	532	PF00498	0.574
LIG_FHA_1	596	602	PF00498	0.676
LIG_FHA_1	623	629	PF00498	0.540
LIG_FHA_1	656	662	PF00498	0.633
LIG_FHA_1	692	698	PF00498	0.733
LIG_FHA_1	769	775	PF00498	0.551
LIG_FHA_2	100	106	PF00498	0.438
LIG_FHA_2	189	195	PF00498	0.788
LIG_FHA_2	358	364	PF00498	0.546
LIG_FHA_2	369	375	PF00498	0.564
LIG_FHA_2	465	471	PF00498	0.544
LIG_FHA_2	572	578	PF00498	0.553
LIG_GBD_Chelix_1	108	116	PF00786	0.452
LIG_HCF-1_HBM_1	243	246	PF13415	0.559
LIG_LIR_Apic_2	528	533	PF02991	0.617
LIG_LIR_Gen_1	650	661	PF02991	0.532
LIG_LIR_Gen_1	722	732	PF02991	0.460
LIG_LIR_LC3C_4	180	185	PF02991	0.530
LIG_LIR_Nem_3	174	179	PF02991	0.614
LIG_LIR_Nem_3	59	65	PF02991	0.522
LIG_LIR_Nem_3	650	656	PF02991	0.530
LIG_LIR_Nem_3	722	728	PF02991	0.439
LIG_MYND_1	553	557	PF01753	0.562
LIG_MYND_1	586	590	PF01753	0.542
LIG_MYND_1	683	687	PF01753	0.573
LIG_NRBOX	213	219	PF00104	0.527
LIG_NRBOX	263	269	PF00104	0.627
LIG_PTAP_UEV_1	648	653	PF05743	0.525
LIG_SH2_GRB2like	412	415	PF00017	0.578
LIG_SH2_PTP2	412	415	PF00017	0.578
LIG_SH2_SRC	412	415	PF00017	0.578
LIG_SH2_STAT5	114	117	PF00017	0.385
LIG_SH2_STAT5	313	316	PF00017	0.511
LIG_SH2_STAT5	412	415	PF00017	0.601
LIG_SH2_STAT5	62	65	PF00017	0.466
LIG_SH2_STAT5	727	730	PF00017	0.483
LIG_SH3_1	167	173	PF00018	0.674
LIG_SH3_1	589	595	PF00018	0.538
LIG_SH3_1	786	792	PF00018	0.707
LIG_SH3_3	154	160	PF00018	0.548
LIG_SH3_3	167	173	PF00018	0.630
LIG_SH3_3	183	189	PF00018	0.643
LIG_SH3_3	235	241	PF00018	0.718
LIG_SH3_3	384	390	PF00018	0.566
LIG_SH3_3	589	595	PF00018	0.649
LIG_SH3_3	62	68	PF00018	0.521
LIG_SH3_3	646	652	PF00018	0.542
LIG_SH3_3	677	683	PF00018	0.691
LIG_SH3_3	786	792	PF00018	0.707
LIG_SH3_CIN85_PxpxPR_1	173	178	PF14604	0.520
LIG_SUMO_SIM_anti_2	514	520	PF11976	0.643
LIG_SUMO_SIM_par_1	127	133	PF11976	0.548
LIG_SUMO_SIM_par_1	384	391	PF11976	0.523
LIG_SUMO_SIM_par_1	67	72	PF11976	0.544
LIG_SUMO_SIM_par_1	79	87	PF11976	0.354
LIG_TRAF2_1	240	243	PF00917	0.559
LIG_TRAF2_1	607	610	PF00917	0.488
LIG_TRAF2_1	704	707	PF00917	0.522
LIG_TRAF2_1	761	764	PF00917	0.528
LIG_TYR_ITIM	60	65	PF00017	0.481
LIG_ULM_U2AF65_1	344	350	PF00076	0.538
LIG_WW_3	687	691	PF00397	0.563
MOD_CDK_SPxxK_3	171	178	PF00069	0.528
MOD_CK1_1	132	138	PF00069	0.735
MOD_CK1_1	159	165	PF00069	0.552
MOD_CK1_1	171	177	PF00069	0.630
MOD_CK1_1	198	204	PF00069	0.587
MOD_CK1_1	237	243	PF00069	0.645
MOD_CK1_1	281	287	PF00069	0.696
MOD_CK1_1	357	363	PF00069	0.710
MOD_CK1_1	429	435	PF00069	0.626
MOD_CK1_1	444	450	PF00069	0.710
MOD_CK1_1	46	52	PF00069	0.561
MOD_CK1_1	581	587	PF00069	0.648
MOD_CK1_1	593	599	PF00069	0.611
MOD_CK1_1	639	645	PF00069	0.590
MOD_CK1_1	654	660	PF00069	0.750
MOD_CK1_1	663	669	PF00069	0.585
MOD_CK1_1	691	697	PF00069	0.666
MOD_CK1_1	87	93	PF00069	0.535
MOD_CK2_1	237	243	PF00069	0.577
MOD_CK2_1	357	363	PF00069	0.535
MOD_CK2_1	464	470	PF00069	0.608
MOD_CK2_1	690	696	PF00069	0.661
MOD_CK2_1	701	707	PF00069	0.456
MOD_CK2_1	799	805	PF00069	0.640
MOD_CK2_1	87	93	PF00069	0.488
MOD_CK2_1	99	105	PF00069	0.487
MOD_Cter_Amidation	562	565	PF01082	0.569
MOD_GlcNHglycan	14	17	PF01048	0.621
MOD_GlcNHglycan	19	22	PF01048	0.609
MOD_GlcNHglycan	247	251	PF01048	0.662
MOD_GlcNHglycan	36	39	PF01048	0.709
MOD_GlcNHglycan	366	369	PF01048	0.645
MOD_GlcNHglycan	422	425	PF01048	0.754
MOD_GlcNHglycan	494	497	PF01048	0.677
MOD_GlcNHglycan	525	528	PF01048	0.558
MOD_GlcNHglycan	540	543	PF01048	0.759
MOD_GlcNHglycan	547	550	PF01048	0.728
MOD_GlcNHglycan	557	560	PF01048	0.730
MOD_GlcNHglycan	580	583	PF01048	0.590
MOD_GlcNHglycan	614	617	PF01048	0.476
MOD_GlcNHglycan	629	633	PF01048	0.599
MOD_GlcNHglycan	638	641	PF01048	0.620
MOD_GlcNHglycan	721	724	PF01048	0.616
MOD_GSK3_1	116	123	PF00069	0.571
MOD_GSK3_1	130	137	PF00069	0.577
MOD_GSK3_1	152	159	PF00069	0.671
MOD_GSK3_1	184	191	PF00069	0.700
MOD_GSK3_1	200	207	PF00069	0.702
MOD_GSK3_1	277	284	PF00069	0.676
MOD_GSK3_1	354	361	PF00069	0.740
MOD_GSK3_1	364	371	PF00069	0.586
MOD_GSK3_1	426	433	PF00069	0.641
MOD_GSK3_1	441	448	PF00069	0.557
MOD_GSK3_1	460	467	PF00069	0.572
MOD_GSK3_1	5	12	PF00069	0.582
MOD_GSK3_1	536	543	PF00069	0.636
MOD_GSK3_1	555	562	PF00069	0.676
MOD_GSK3_1	591	598	PF00069	0.674
MOD_GSK3_1	628	635	PF00069	0.704
MOD_GSK3_1	639	646	PF00069	0.531
MOD_GSK3_1	647	654	PF00069	0.741
MOD_GSK3_1	655	662	PF00069	0.599
MOD_GSK3_1	688	695	PF00069	0.593
MOD_GSK3_1	764	771	PF00069	0.635
MOD_GSK3_1	87	94	PF00069	0.532
MOD_N-GLC_1	448	453	PF02516	0.684
MOD_N-GLC_1	537	542	PF02516	0.571
MOD_N-GLC_1	605	610	PF02516	0.474
MOD_N-GLC_1	659	664	PF02516	0.643
MOD_NEK2_1	116	121	PF00069	0.574
MOD_NEK2_1	145	150	PF00069	0.597
MOD_NEK2_1	628	633	PF00069	0.648
MOD_NEK2_1	643	648	PF00069	0.638
MOD_NEK2_1	721	726	PF00069	0.431
MOD_NEK2_1	97	102	PF00069	0.436
MOD_PIKK_1	161	167	PF00454	0.571
MOD_PKA_1	278	284	PF00069	0.569
MOD_PKA_1	295	301	PF00069	0.466
MOD_PKA_2	17	23	PF00069	0.699
MOD_PKA_2	26	32	PF00069	0.574
MOD_PKA_2	277	283	PF00069	0.784
MOD_PKA_2	295	301	PF00069	0.504
MOD_PKA_2	347	353	PF00069	0.600
MOD_PKA_2	46	52	PF00069	0.513
MOD_PKA_2	536	542	PF00069	0.702
MOD_PKA_2	602	608	PF00069	0.567
MOD_PKA_2	612	618	PF00069	0.477
MOD_PKA_2	663	669	PF00069	0.528
MOD_PKA_2	689	695	PF00069	0.564
MOD_Plk_2-3	799	805	PF00069	0.688
MOD_Plk_4	263	269	PF00069	0.734
MOD_Plk_4	313	319	PF00069	0.551
MOD_ProDKin_1	130	136	PF00069	0.629
MOD_ProDKin_1	137	143	PF00069	0.572
MOD_ProDKin_1	152	158	PF00069	0.548
MOD_ProDKin_1	171	177	PF00069	0.659
MOD_ProDKin_1	195	201	PF00069	0.707
MOD_ProDKin_1	237	243	PF00069	0.713
MOD_ProDKin_1	591	597	PF00069	0.622
MOD_ProDKin_1	669	675	PF00069	0.568
MOD_ProDKin_1	701	707	PF00069	0.535
MOD_ProDKin_1	785	791	PF00069	0.707
MOD_SUMO_rev_2	357	367	PF00179	0.538
TRG_DiLeu_BaLyEn_6	550	555	PF01217	0.665
TRG_DiLeu_BaLyEn_6	583	588	PF01217	0.549
TRG_ENDOCYTIC_2	62	65	PF00928	0.466
TRG_ENDOCYTIC_2	718	721	PF00928	0.481
TRG_ENDOCYTIC_2	732	735	PF00928	0.402
TRG_ER_diArg_1	295	297	PF00400	0.664
TRG_ER_diArg_1	318	320	PF00400	0.606
TRG_ER_diArg_1	344	347	PF00400	0.688
TRG_ER_diArg_1	519	521	PF00400	0.627
TRG_ER_diArg_1	697	700	PF00400	0.605
TRG_ER_diArg_1	74	76	PF00400	0.531
TRG_ER_diArg_1	753	756	PF00400	0.445
TRG_NLS_MonoCore_2	344	349	PF00514	0.691
TRG_NLS_MonoExtC_3	343	348	PF00514	0.690
TRG_NLS_MonoExtN_4	344	349	PF00514	0.689

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HWT6	Leptomonas seymouri	31%	100%
A0A3Q8IB42	Leishmania donovani	67%	100%
A4HXZ8	Leishmania infantum	66%	100%
E9ARR2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	65%	100%
Q4QDR7	Leishmania major	66%	98%