Protein kintoun

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Protein kintoun

Gene product:

pre-RNA processing PIH1/Nop17, putative

Species:

Leishmania braziliensis

UniProt:

A4H9N3_LEIBR

TriTrypDb:

LbrM.18.1330 , LBRM2903_180019000

Length:

765

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H9N3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H9N3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	163	167	PF00656	0.585
CLV_C14_Caspase3-7	376	380	PF00656	0.517
CLV_C14_Caspase3-7	487	491	PF00656	0.752
CLV_C14_Caspase3-7	602	606	PF00656	0.660
CLV_C14_Caspase3-7	641	645	PF00656	0.578
CLV_NRD_NRD_1	181	183	PF00675	0.542
CLV_NRD_NRD_1	22	24	PF00675	0.555
CLV_NRD_NRD_1	264	266	PF00675	0.287
CLV_NRD_NRD_1	406	408	PF00675	0.346
CLV_NRD_NRD_1	447	449	PF00675	0.236
CLV_NRD_NRD_1	480	482	PF00675	0.644
CLV_NRD_NRD_1	664	666	PF00675	0.650
CLV_NRD_NRD_1	731	733	PF00675	0.521
CLV_NRD_NRD_1	76	78	PF00675	0.500
CLV_PCSK_FUR_1	262	266	PF00082	0.200
CLV_PCSK_FUR_1	748	752	PF00082	0.651
CLV_PCSK_KEX2_1	181	183	PF00082	0.542
CLV_PCSK_KEX2_1	22	24	PF00082	0.555
CLV_PCSK_KEX2_1	264	266	PF00082	0.287
CLV_PCSK_KEX2_1	388	390	PF00082	0.266
CLV_PCSK_KEX2_1	406	408	PF00082	0.266
CLV_PCSK_KEX2_1	731	733	PF00082	0.524
CLV_PCSK_KEX2_1	750	752	PF00082	0.498
CLV_PCSK_KEX2_1	76	78	PF00082	0.500
CLV_PCSK_PC1ET2_1	388	390	PF00082	0.337
CLV_PCSK_PC1ET2_1	750	752	PF00082	0.616
CLV_PCSK_PC7_1	384	390	PF00082	0.381
CLV_PCSK_SKI1_1	104	108	PF00082	0.524
CLV_PCSK_SKI1_1	145	149	PF00082	0.494
CLV_PCSK_SKI1_1	157	161	PF00082	0.564
CLV_PCSK_SKI1_1	331	335	PF00082	0.686
CLV_PCSK_SKI1_1	456	460	PF00082	0.296
CLV_PCSK_SKI1_1	481	485	PF00082	0.458
CLV_PCSK_SKI1_1	759	763	PF00082	0.560
DEG_SPOP_SBC_1	139	143	PF00917	0.445
DEG_SPOP_SBC_1	210	214	PF00917	0.593
DEG_SPOP_SBC_1	325	329	PF00917	0.745
DEG_SPOP_SBC_1	517	521	PF00917	0.508
DOC_CKS1_1	273	278	PF01111	0.487
DOC_CKS1_1	556	561	PF01111	0.769
DOC_CYCLIN_yCln2_LP_2	437	443	PF00134	0.520
DOC_CYCLIN_yCln2_LP_2	556	562	PF00134	0.683
DOC_MAPK_FxFP_2	100	103	PF00069	0.372
DOC_MAPK_gen_1	406	413	PF00069	0.559
DOC_MAPK_gen_1	748	756	PF00069	0.588
DOC_MAPK_MEF2A_6	406	415	PF00069	0.534
DOC_MAPK_MEF2A_6	432	441	PF00069	0.562
DOC_MAPK_MEF2A_6	456	465	PF00069	0.482
DOC_MAPK_NFAT4_5	456	464	PF00069	0.476
DOC_PP1_RVXF_1	123	130	PF00149	0.381
DOC_PP1_RVXF_1	219	226	PF00149	0.589
DOC_PP1_RVXF_1	397	403	PF00149	0.504
DOC_PP2B_LxvP_1	437	440	PF13499	0.537
DOC_PP4_FxxP_1	100	103	PF00568	0.372
DOC_USP7_MATH_1	139	143	PF00917	0.667
DOC_USP7_MATH_1	167	171	PF00917	0.653
DOC_USP7_MATH_1	188	192	PF00917	0.606
DOC_USP7_MATH_1	193	197	PF00917	0.680
DOC_USP7_MATH_1	204	208	PF00917	0.654
DOC_USP7_MATH_1	210	214	PF00917	0.480
DOC_USP7_MATH_1	323	327	PF00917	0.665
DOC_USP7_MATH_1	332	336	PF00917	0.786
DOC_USP7_MATH_1	352	356	PF00917	0.675
DOC_USP7_MATH_1	518	522	PF00917	0.637
DOC_USP7_MATH_1	604	608	PF00917	0.763
DOC_USP7_MATH_1	610	614	PF00917	0.771
DOC_USP7_MATH_1	638	642	PF00917	0.747
DOC_USP7_UBL2_3	729	733	PF12436	0.603
DOC_WW_Pin1_4	11	16	PF00397	0.698
DOC_WW_Pin1_4	189	194	PF00397	0.641
DOC_WW_Pin1_4	211	216	PF00397	0.420
DOC_WW_Pin1_4	233	238	PF00397	0.587
DOC_WW_Pin1_4	272	277	PF00397	0.477
DOC_WW_Pin1_4	314	319	PF00397	0.730
DOC_WW_Pin1_4	321	326	PF00397	0.733
DOC_WW_Pin1_4	413	418	PF00397	0.579
DOC_WW_Pin1_4	534	539	PF00397	0.731
DOC_WW_Pin1_4	543	548	PF00397	0.674
DOC_WW_Pin1_4	555	560	PF00397	0.718
DOC_WW_Pin1_4	608	613	PF00397	0.760
LIG_14-3-3_CanoR_1	384	392	PF00244	0.569
LIG_14-3-3_CanoR_1	406	411	PF00244	0.494
LIG_14-3-3_CanoR_1	456	462	PF00244	0.520
LIG_14-3-3_CanoR_1	751	755	PF00244	0.465
LIG_APCC_ABBAyCdc20_2	55	61	PF00400	0.577
LIG_BIR_III_2	293	297	PF00653	0.481
LIG_BRCT_BRCA1_1	235	239	PF00533	0.476
LIG_BRCT_BRCA1_1	257	261	PF00533	0.537
LIG_BRCT_BRCA1_1	518	522	PF00533	0.508
LIG_BRCT_BRCA1_1	96	100	PF00533	0.438
LIG_deltaCOP1_diTrp_1	379	383	PF00928	0.476
LIG_FHA_1	227	233	PF00498	0.484
LIG_FHA_1	303	309	PF00498	0.528
LIG_FHA_1	359	365	PF00498	0.596
LIG_FHA_1	458	464	PF00498	0.480
LIG_FHA_1	596	602	PF00498	0.713
LIG_FHA_1	614	620	PF00498	0.755
LIG_FHA_1	669	675	PF00498	0.671
LIG_FHA_2	161	167	PF00498	0.556
LIG_FHA_2	345	351	PF00498	0.617
LIG_FHA_2	41	47	PF00498	0.497
LIG_FHA_2	440	446	PF00498	0.528
LIG_FHA_2	540	546	PF00498	0.703
LIG_FHA_2	548	554	PF00498	0.682
LIG_FHA_2	73	79	PF00498	0.498
LIG_LIR_Apic_2	170	175	PF02991	0.447
LIG_LIR_Apic_2	97	103	PF02991	0.402
LIG_LIR_Gen_1	146	154	PF02991	0.351
LIG_LIR_Gen_1	236	247	PF02991	0.485
LIG_LIR_Gen_1	519	530	PF02991	0.510
LIG_LIR_Gen_1	56	67	PF02991	0.471
LIG_LIR_Gen_1	95	106	PF02991	0.416
LIG_LIR_Nem_3	146	150	PF02991	0.395
LIG_LIR_Nem_3	184	189	PF02991	0.560
LIG_LIR_Nem_3	236	242	PF02991	0.485
LIG_LIR_Nem_3	401	405	PF02991	0.478
LIG_LIR_Nem_3	519	525	PF02991	0.510
LIG_LIR_Nem_3	56	62	PF02991	0.457
LIG_LIR_Nem_3	95	101	PF02991	0.433
LIG_Pex14_2	96	100	PF04695	0.445
LIG_RPA_C_Fungi	402	414	PF08784	0.474
LIG_RPA_C_Fungi	706	718	PF08784	0.630
LIG_SH2_CRK	186	190	PF00017	0.587
LIG_SH2_SRC	186	189	PF00017	0.606
LIG_SH2_STAT3	82	85	PF00017	0.506
LIG_SH2_STAT5	201	204	PF00017	0.418
LIG_SH2_STAT5	367	370	PF00017	0.388
LIG_SH2_STAT5	760	763	PF00017	0.643
LIG_SH2_STAT5	82	85	PF00017	0.518
LIG_SH3_3	221	227	PF00018	0.336
LIG_SH3_3	293	299	PF00018	0.675
LIG_SH3_3	387	393	PF00018	0.385
LIG_SH3_3	462	468	PF00018	0.326
LIG_SH3_3	551	557	PF00018	0.728
LIG_SH3_3	606	612	PF00018	0.531
LIG_SUMO_SIM_anti_2	434	440	PF11976	0.475
LIG_SUMO_SIM_anti_2	45	52	PF11976	0.376
LIG_SUMO_SIM_anti_2	576	582	PF11976	0.414
LIG_SUMO_SIM_par_1	107	115	PF11976	0.417
LIG_SUMO_SIM_par_1	173	179	PF11976	0.414
LIG_SUMO_SIM_par_1	228	234	PF11976	0.421
LIG_SUMO_SIM_par_1	268	275	PF11976	0.451
LIG_SUMO_SIM_par_1	45	52	PF11976	0.376
LIG_SUMO_SIM_par_1	457	462	PF11976	0.413
LIG_SUMO_SIM_par_1	597	602	PF11976	0.516
LIG_TRAF2_1	42	45	PF00917	0.499
LIG_TRAF2_1	442	445	PF00917	0.391
LIG_TRAF2_1	710	713	PF00917	0.565
LIG_TRAF2_1	719	722	PF00917	0.514
LIG_UBA3_1	47	55	PF00899	0.370
LIG_WW_2	468	471	PF00397	0.667
MOD_CDC14_SPxK_1	546	549	PF00782	0.748
MOD_CDK_SPK_2	233	238	PF00069	0.223
MOD_CDK_SPxK_1	543	549	PF00069	0.696
MOD_CK1_1	114	120	PF00069	0.487
MOD_CK1_1	132	138	PF00069	0.703
MOD_CK1_1	143	149	PF00069	0.542
MOD_CK1_1	191	197	PF00069	0.632
MOD_CK1_1	211	217	PF00069	0.438
MOD_CK1_1	269	275	PF00069	0.363
MOD_CK1_1	284	290	PF00069	0.587
MOD_CK1_1	314	320	PF00069	0.696
MOD_CK1_1	324	330	PF00069	0.673
MOD_CK1_1	335	341	PF00069	0.762
MOD_CK1_1	355	361	PF00069	0.707
MOD_CK1_1	511	517	PF00069	0.794
MOD_CK1_1	537	543	PF00069	0.746
MOD_CK1_1	613	619	PF00069	0.782
MOD_CK1_1	627	633	PF00069	0.735
MOD_CK2_1	117	123	PF00069	0.573
MOD_CK2_1	167	173	PF00069	0.585
MOD_CK2_1	24	30	PF00069	0.705
MOD_CK2_1	344	350	PF00069	0.609
MOD_CK2_1	40	46	PF00069	0.489
MOD_CK2_1	439	445	PF00069	0.265
MOD_CK2_1	518	524	PF00069	0.670
MOD_CK2_1	539	545	PF00069	0.751
MOD_CK2_1	547	553	PF00069	0.684
MOD_CK2_1	72	78	PF00069	0.504
MOD_DYRK1A_RPxSP_1	543	547	PF00069	0.774
MOD_GlcNHglycan	119	122	PF01048	0.591
MOD_GlcNHglycan	130	134	PF01048	0.654
MOD_GlcNHglycan	142	145	PF01048	0.521
MOD_GlcNHglycan	193	196	PF01048	0.509
MOD_GlcNHglycan	206	209	PF01048	0.638
MOD_GlcNHglycan	252	255	PF01048	0.358
MOD_GlcNHglycan	26	29	PF01048	0.761
MOD_GlcNHglycan	328	331	PF01048	0.639
MOD_GlcNHglycan	354	357	PF01048	0.715
MOD_GlcNHglycan	550	553	PF01048	0.776
MOD_GlcNHglycan	640	643	PF01048	0.783
MOD_GlcNHglycan	644	647	PF01048	0.764
MOD_GSK3_1	128	135	PF00069	0.629
MOD_GSK3_1	139	146	PF00069	0.635
MOD_GSK3_1	157	164	PF00069	0.476
MOD_GSK3_1	189	196	PF00069	0.606
MOD_GSK3_1	204	211	PF00069	0.594
MOD_GSK3_1	22	29	PF00069	0.732
MOD_GSK3_1	265	272	PF00069	0.371
MOD_GSK3_1	277	284	PF00069	0.145
MOD_GSK3_1	317	324	PF00069	0.692
MOD_GSK3_1	331	338	PF00069	0.690
MOD_GSK3_1	352	359	PF00069	0.656
MOD_GSK3_1	367	374	PF00069	0.361
MOD_GSK3_1	506	513	PF00069	0.658
MOD_GSK3_1	539	546	PF00069	0.729
MOD_GSK3_1	604	611	PF00069	0.570
MOD_GSK3_1	634	641	PF00069	0.709
MOD_GSK3_1	750	757	PF00069	0.644
MOD_N-GLC_1	277	282	PF02516	0.328
MOD_N-GLC_1	624	629	PF02516	0.561
MOD_N-GLC_2	149	151	PF02516	0.356
MOD_NEK2_1	111	116	PF00069	0.455
MOD_NEK2_1	129	134	PF00069	0.690
MOD_NEK2_1	209	214	PF00069	0.439
MOD_NEK2_1	277	282	PF00069	0.446
MOD_NEK2_1	452	457	PF00069	0.425
MOD_NEK2_1	459	464	PF00069	0.398
MOD_NEK2_1	634	639	PF00069	0.577
MOD_NEK2_1	705	710	PF00069	0.402
MOD_PIKK_1	176	182	PF00454	0.502
MOD_PIKK_1	40	46	PF00454	0.402
MOD_PIKK_1	508	514	PF00454	0.740
MOD_PIKK_1	654	660	PF00454	0.776
MOD_PK_1	406	412	PF00069	0.223
MOD_PKA_1	22	28	PF00069	0.550
MOD_PKA_1	406	412	PF00069	0.223
MOD_PKA_1	750	756	PF00069	0.635
MOD_PKA_2	161	167	PF00069	0.627
MOD_PKA_2	22	28	PF00069	0.550
MOD_PKA_2	281	287	PF00069	0.451
MOD_PKA_2	302	308	PF00069	0.691
MOD_PKA_2	344	350	PF00069	0.731
MOD_PKA_2	371	377	PF00069	0.369
MOD_PKA_2	383	389	PF00069	0.432
MOD_PKA_2	406	412	PF00069	0.464
MOD_PKA_2	741	747	PF00069	0.584
MOD_PKA_2	750	756	PF00069	0.583
MOD_Plk_1	277	283	PF00069	0.328
MOD_Plk_1	604	610	PF00069	0.598
MOD_Plk_1	94	100	PF00069	0.452
MOD_Plk_4	266	272	PF00069	0.475
MOD_Plk_4	287	293	PF00069	0.648
MOD_Plk_4	406	412	PF00069	0.350
MOD_ProDKin_1	11	17	PF00069	0.699
MOD_ProDKin_1	189	195	PF00069	0.647
MOD_ProDKin_1	211	217	PF00069	0.420
MOD_ProDKin_1	233	239	PF00069	0.484
MOD_ProDKin_1	272	278	PF00069	0.330
MOD_ProDKin_1	314	320	PF00069	0.732
MOD_ProDKin_1	321	327	PF00069	0.733
MOD_ProDKin_1	413	419	PF00069	0.473
MOD_ProDKin_1	534	540	PF00069	0.735
MOD_ProDKin_1	543	549	PF00069	0.675
MOD_ProDKin_1	555	561	PF00069	0.718
MOD_ProDKin_1	608	614	PF00069	0.761
MOD_SUMO_rev_2	120	127	PF00179	0.612
MOD_SUMO_rev_2	161	170	PF00179	0.398
MOD_SUMO_rev_2	681	690	PF00179	0.587
TRG_DiLeu_BaEn_2	658	664	PF01217	0.771
TRG_DiLeu_BaEn_4	712	718	PF01217	0.385
TRG_DiLeu_BaEn_4	78	84	PF01217	0.505
TRG_DiLeu_BaLyEn_6	551	556	PF01217	0.552
TRG_ENDOCYTIC_2	186	189	PF00928	0.580
TRG_ENDOCYTIC_2	433	436	PF00928	0.470
TRG_ER_diArg_1	10	13	PF00400	0.514
TRG_ER_diArg_1	181	183	PF00400	0.542
TRG_ER_diArg_1	263	265	PF00400	0.344
TRG_ER_diArg_1	405	407	PF00400	0.427
TRG_ER_diArg_1	690	693	PF00400	0.540

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I3H0	Leptomonas seymouri	49%	95%
A0A0S4JRA4	Bodo saltans	34%	100%
A0A1X0P812	Trypanosomatidae	38%	100%
A0A3Q8IB73	Leishmania donovani	75%	100%
A0A3R7N1E2	Trypanosoma rangeli	38%	100%
A4HXZ7	Leishmania infantum	75%	100%
D0A5A8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
E9ARR1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	100%
Q4QDR8	Leishmania major	77%	100%
V5AZ63	Trypanosoma cruzi	37%	100%