Guanine nucleotide-binding protein subunit beta-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Periodic tryptophan protein 2 homolog, putative

Species:

Leishmania braziliensis

UniProt:

A4H9J4_LEIBR

TriTrypDb:

LbrM.18.0920 , LBRM2903_180014600

Length:

942

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Show entries

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	11
GO:0005840	ribosome	5	12
GO:0030684	preribosome	3	1
GO:0032040	small-subunit processome	4	1
GO:0032991	protein-containing complex	1	12
GO:0034388	Pwp2p-containing subcomplex of 90S preribosome	3	1
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12

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Expansion

Sequence features

A4H9J4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H9J4

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0000028	ribosomal small subunit assembly	7	1
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	10	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006364	rRNA processing	8	1
GO:0006396	RNA processing	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0016043	cellular component organization	3	1

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	262	266	PF00656	0.560
CLV_C14_Caspase3-7	465	469	PF00656	0.535
CLV_NRD_NRD_1	181	183	PF00675	0.524
CLV_NRD_NRD_1	231	233	PF00675	0.479
CLV_NRD_NRD_1	274	276	PF00675	0.573
CLV_NRD_NRD_1	595	597	PF00675	0.405
CLV_NRD_NRD_1	633	635	PF00675	0.528
CLV_NRD_NRD_1	723	725	PF00675	0.568
CLV_NRD_NRD_1	741	743	PF00675	0.466
CLV_NRD_NRD_1	796	798	PF00675	0.394

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE02	Leptomonas seymouri	88%	100%
A0A0S4J1U6	Bodo saltans	62%	99%
A0A1X0P754	Trypanosomatidae	71%	100%
A0A3S5H735	Leishmania donovani	92%	100%
A0A422P1S2	Trypanosoma rangeli	70%	100%
A4HXV7	Leishmania infantum	92%	100%
C9ZZU6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	67%	100%
E9ARM0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
P25635	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	100%
P91341	Caenorhabditis elegans	27%	100%

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