Dpy-30 motif containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4H9H0_LEIBR

TriTrypDb:

LbrM.18.0680 , LBRM2903_180011600

Length:

196

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Cellular components
Term	Name	Level	Count
GO:0032991	protein-containing complex	1	1
GO:0034708	methyltransferase complex	4	1
GO:0035097	histone methyltransferase complex	3	1
GO:0044666	MLL3/4 complex	4	1
GO:0048188	Set1C/COMPASS complex	4	1
GO:0140513	nuclear protein-containing complex	2	1
GO:1902494	catalytic complex	2	1
GO:1990234	transferase complex	3	1

Expansion

Sequence features

A4H9H0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H9H0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	87	91	PF00082	0.327
DEG_APCC_DBOX_1	86	94	PF00400	0.527
DEG_Nend_Nbox_1	1	3	PF02207	0.702
DOC_MAPK_MEF2A_6	87	94	PF00069	0.527
DOC_MAPK_NFAT4_5	87	95	PF00069	0.527
DOC_USP7_MATH_1	126	130	PF00917	0.640
DOC_USP7_MATH_2	125	131	PF00917	0.560
DOC_USP7_UBL2_3	135	139	PF12436	0.614
DOC_WW_Pin1_4	175	180	PF00397	0.569
DOC_WW_Pin1_4	45	50	PF00397	0.623
LIG_BRCT_BRCA1_1	47	51	PF00533	0.713
LIG_BRCT_BRCA1_1	52	56	PF00533	0.608
LIG_FHA_1	180	186	PF00498	0.577
LIG_LIR_Apic_2	76	80	PF02991	0.531
LIG_LIR_Nem_3	53	59	PF02991	0.689
LIG_NRBOX	13	19	PF00104	0.457
LIG_SH2_NCK_1	77	81	PF00017	0.531
LIG_SH2_STAT5	84	87	PF00017	0.487
LIG_SH3_2	37	42	PF14604	0.556
LIG_SH3_3	100	106	PF00018	0.520
LIG_SH3_3	118	124	PF00018	0.612
LIG_SH3_3	34	40	PF00018	0.717
LIG_TRAF2_1	156	159	PF00917	0.532
MOD_CDK_SPK_2	175	180	PF00069	0.569
MOD_CK1_1	130	136	PF00069	0.665
MOD_CK1_1	166	172	PF00069	0.701
MOD_CK1_1	173	179	PF00069	0.683
MOD_CK1_1	190	196	PF00069	0.480
MOD_CK2_1	1	7	PF00069	0.563
MOD_GlcNHglycan	130	133	PF01048	0.707
MOD_GlcNHglycan	174	178	PF01048	0.680
MOD_GlcNHglycan	189	192	PF01048	0.610
MOD_GlcNHglycan	25	28	PF01048	0.553
MOD_GlcNHglycan	52	55	PF01048	0.609
MOD_GlcNHglycan	56	59	PF01048	0.629
MOD_GSK3_1	126	133	PF00069	0.671
MOD_GSK3_1	159	166	PF00069	0.622
MOD_GSK3_1	168	175	PF00069	0.678
MOD_GSK3_1	50	57	PF00069	0.617
MOD_N-GLC_1	127	132	PF02516	0.576
MOD_N-GLC_2	61	63	PF02516	0.549
MOD_NEK2_1	1	6	PF00069	0.687
MOD_NEK2_1	168	173	PF00069	0.751
MOD_NEK2_1	43	48	PF00069	0.596
MOD_NEK2_1	52	57	PF00069	0.676
MOD_PIKK_1	159	165	PF00454	0.499
MOD_PKA_2	166	172	PF00069	0.735
MOD_Plk_1	10	16	PF00069	0.573
MOD_Plk_1	85	91	PF00069	0.527
MOD_ProDKin_1	175	181	PF00069	0.569
MOD_ProDKin_1	45	51	PF00069	0.623
MOD_SUMO_for_1	41	44	PF00179	0.563
TRG_DiLeu_BaLyEn_6	88	93	PF01217	0.527

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PB06	Leptomonas seymouri	43%	87%
A0A3S5H731	Leishmania donovani	68%	98%