Putative phosphatidic acid phosphatase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Download

Quick info

Protein:

Gene product:

phosphatidic acid phosphatase, putative

Species:

Leishmania braziliensis

UniProt:

A4H9F2_LEIBR

TriTrypDb:

LbrM.18.0500

Length:

269

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4H9F2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H9F2

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0008195	phosphatidate phosphatase activity	6	2
GO:0016787	hydrolase activity	2	2
GO:0016788	hydrolase activity, acting on ester bonds	3	2
GO:0016791	phosphatase activity	5	2
GO:0042578	phosphoric ester hydrolase activity	4	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	196	198	PF00675	0.548
CLV_NRD_NRD_1	80	82	PF00675	0.632
CLV_NRD_NRD_1	98	100	PF00675	0.394
CLV_PCSK_FUR_1	101	105	PF00082	0.612
CLV_PCSK_KEX2_1	103	105	PF00082	0.551
CLV_PCSK_KEX2_1	196	198	PF00082	0.548
CLV_PCSK_KEX2_1	80	82	PF00082	0.632
CLV_PCSK_KEX2_1	98	100	PF00082	0.394
CLV_PCSK_PC1ET2_1	103	105	PF00082	0.613
CLV_PCSK_PC7_1	99	105	PF00082	0.613
CLV_PCSK_SKI1_1	103	107	PF00082	0.612
CLV_PCSK_SKI1_1	117	121	PF00082	0.360
CLV_Separin_Metazoa	114	118	PF03568	0.730
DOC_ANK_TNKS_1	218	225	PF00023	0.817
DOC_ANK_TNKS_1	4	11	PF00023	0.778
DOC_CYCLIN_yCln2_LP_2	11	17	PF00134	0.754
DOC_MAPK_gen_1	103	112	PF00069	0.787
DOC_MAPK_MEF2A_6	5	13	PF00069	0.772
DOC_PP1_RVXF_1	115	122	PF00149	0.734
DOC_PP2B_LxvP_1	11	14	PF13499	0.758
DOC_PP2B_LxvP_1	34	37	PF13499	0.825
DOC_PP4_FxxP_1	238	241	PF00568	0.813
DOC_USP7_MATH_1	225	229	PF00917	0.831
DOC_USP7_MATH_1	244	248	PF00917	0.599
DOC_USP7_MATH_1	252	256	PF00917	0.751
DOC_USP7_MATH_1	37	41	PF00917	0.819
DOC_USP7_MATH_1	92	96	PF00917	0.822
DOC_WW_Pin1_4	161	166	PF00397	0.574
DOC_WW_Pin1_4	4	9	PF00397	0.783
DOC_WW_Pin1_4	62	67	PF00397	0.824
LIG_14-3-3_CanoR_1	26	34	PF00244	0.815
LIG_14-3-3_CanoR_1	41	46	PF00244	0.637
LIG_14-3-3_CanoR_1	80	86	PF00244	0.823
LIG_Actin_WH2_2	103	119	PF00022	0.764
LIG_BIR_II_1	1	5	PF00653	0.803
LIG_BIR_III_1	1	5	PF00653	0.803
LIG_BIR_III_3	1	5	PF00653	0.803
LIG_BRCT_BRCA1_1	155	159	PF00533	0.558
LIG_BRCT_BRCA1_1	163	167	PF00533	0.470
LIG_CaM_NSCaTE_8	170	177	PF13499	0.549
LIG_deltaCOP1_diTrp_1	149	159	PF00928	0.546
LIG_eIF4E_1	207	213	PF01652	0.784
LIG_FHA_1	167	173	PF00498	0.449
LIG_FHA_1	209	215	PF00498	0.790
LIG_FHA_1	260	266	PF00498	0.836
LIG_FHA_1	86	92	PF00498	0.823
LIG_GBD_Chelix_1	181	189	PF00786	0.549
LIG_LIR_Apic_2	236	241	PF02991	0.815
LIG_LIR_Apic_2	30	36	PF02991	0.822
LIG_LIR_Gen_1	149	160	PF02991	0.547
LIG_LIR_Gen_1	169	178	PF02991	0.199
LIG_LIR_Nem_3	149	155	PF02991	0.539
LIG_LIR_Nem_3	169	173	PF02991	0.199
LIG_LIR_Nem_3	90	96	PF02991	0.824
LIG_LYPXL_yS_3	93	96	PF13949	0.823
LIG_OCRL_FandH_1	120	132	PF00620	0.650
LIG_Pex14_2	118	122	PF04695	0.730
LIG_REV1ctd_RIR_1	118	127	PF16727	0.727
LIG_SH2_SRC	207	210	PF00017	0.782
LIG_SH2_SRC	33	36	PF00017	0.825
LIG_SH2_STAT5	127	130	PF00017	0.549
LIG_SH2_STAT5	146	149	PF00017	0.322
LIG_SH2_STAT5	18	21	PF00017	0.759
LIG_SH2_STAT5	183	186	PF00017	0.549
LIG_SH2_STAT5	33	36	PF00017	0.637
LIG_SH3_3	162	168	PF00018	0.564
LIG_SUMO_SIM_anti_2	211	217	PF11976	0.794
LIG_SUMO_SIM_par_1	241	250	PF11976	0.830
LIG_SUMO_SIM_par_1	67	73	PF11976	0.828
LIG_SxIP_EBH_1	80	90	PF03271	0.824
LIG_TRAF2_1	261	264	PF00917	0.837
LIG_TYR_ITIM	91	96	PF00017	0.824
LIG_WRC_WIRS_1	19	24	PF05994	0.772
MOD_CK1_1	246	252	PF00069	0.840
MOD_CK1_1	87	93	PF00069	0.827
MOD_CK2_1	233	239	PF00069	0.824
MOD_CK2_1	254	260	PF00069	0.853
MOD_GlcNHglycan	175	178	PF01048	0.549
MOD_GlcNHglycan	256	259	PF01048	0.656
MOD_GlcNHglycan	43	46	PF01048	0.625
MOD_GlcNHglycan	72	75	PF01048	0.628
MOD_GlcNHglycan	76	79	PF01048	0.572
MOD_GlcNHglycan	81	84	PF01048	0.518
MOD_GSK3_1	18	25	PF00069	0.774
MOD_GSK3_1	243	250	PF00069	0.836
MOD_GSK3_1	37	44	PF00069	0.585
MOD_GSK3_1	70	77	PF00069	0.829
MOD_N-GLC_1	253	258	PF02516	0.652
MOD_NEK2_1	17	22	PF00069	0.761
MOD_NEK2_1	173	178	PF00069	0.549
MOD_NEK2_1	214	219	PF00069	0.804
MOD_NEK2_1	70	75	PF00069	0.831
MOD_NEK2_2	168	173	PF00069	0.449
MOD_NEK2_2	18	23	PF00069	0.768
MOD_NEK2_2	225	230	PF00069	0.831
MOD_PIKK_1	214	220	PF00454	0.805
MOD_PIKK_1	259	265	PF00454	0.841
MOD_PKA_2	22	28	PF00069	0.796
MOD_PKA_2	79	85	PF00069	0.824
MOD_Plk_1	148	154	PF00069	0.539
MOD_Plk_1	208	214	PF00069	0.785
MOD_Plk_1	225	231	PF00069	0.618
MOD_Plk_4	208	214	PF00069	0.785
MOD_ProDKin_1	161	167	PF00069	0.573
MOD_ProDKin_1	4	10	PF00069	0.780
MOD_ProDKin_1	62	68	PF00069	0.821
TRG_DiLeu_BaEn_1	264	269	PF01217	0.834
TRG_DiLeu_BaEn_2	113	119	PF01217	0.731
TRG_DiLeu_BaLyEn_6	65	70	PF01217	0.820
TRG_ENDOCYTIC_2	93	96	PF00928	0.823
TRG_ER_diArg_1	142	145	PF00400	0.554
TRG_ER_diArg_1	98	101	PF00400	0.817
TRG_NES_CRM1_1	114	126	PF08389	0.728
TRG_NLS_MonoExtN_4	100	107	PF00514	0.812