| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 11 |
| NetGPI | no | yes: 0, no: 11 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005737 | cytoplasm | 2 | 1 |
| GO:0031974 | membrane-enclosed lumen | 2 | 1 |
| GO:0031981 | nuclear lumen | 5 | 1 |
| GO:0032838 | plasma membrane bounded cell projection cytoplasm | 4 | 1 |
| GO:0043233 | organelle lumen | 3 | 1 |
| GO:0070013 | intracellular organelle lumen | 4 | 1 |
| GO:0097014 | ciliary plasm | 5 | 1 |
| GO:0099568 | cytoplasmic region | 3 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 1 |
Related structures:
AlphaFold database: A4H996
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005975 | carbohydrate metabolic process | 3 | 12 |
| GO:0006020 | inositol metabolic process | 4 | 11 |
| GO:0006021 | inositol biosynthetic process | 5 | 11 |
| GO:0006066 | alcohol metabolic process | 3 | 12 |
| GO:0006629 | lipid metabolic process | 3 | 8 |
| GO:0006644 | phospholipid metabolic process | 4 | 8 |
| GO:0006650 | glycerophospholipid metabolic process | 5 | 8 |
| GO:0006661 | phosphatidylinositol biosynthetic process | 6 | 8 |
| GO:0006793 | phosphorus metabolic process | 3 | 12 |
| GO:0006796 | phosphate-containing compound metabolic process | 4 | 12 |
| GO:0008152 | metabolic process | 1 | 12 |
| GO:0008610 | lipid biosynthetic process | 4 | 8 |
| GO:0008654 | phospholipid biosynthetic process | 5 | 8 |
| GO:0009056 | catabolic process | 2 | 12 |
| GO:0009058 | biosynthetic process | 2 | 12 |
| GO:0009987 | cellular process | 1 | 12 |
| GO:0016051 | carbohydrate biosynthetic process | 4 | 11 |
| GO:0016311 | dephosphorylation | 5 | 12 |
| GO:0019637 | organophosphate metabolic process | 3 | 12 |
| GO:0019751 | polyol metabolic process | 4 | 12 |
| GO:0034637 | obsolete cellular carbohydrate biosynthetic process | 4 | 11 |
| GO:0043647 | inositol phosphate metabolic process | 4 | 12 |
| GO:0044237 | cellular metabolic process | 2 | 12 |
| GO:0044238 | primary metabolic process | 2 | 12 |
| GO:0044249 | cellular biosynthetic process | 3 | 12 |
| GO:0044255 | cellular lipid metabolic process | 3 | 8 |
| GO:0044262 | obsolete cellular carbohydrate metabolic process | 3 | 12 |
| GO:0044281 | small molecule metabolic process | 2 | 12 |
| GO:0044282 | small molecule catabolic process | 3 | 12 |
| GO:0044283 | small molecule biosynthetic process | 3 | 11 |
| GO:0045017 | glycerolipid biosynthetic process | 4 | 8 |
| GO:0046164 | alcohol catabolic process | 4 | 12 |
| GO:0046165 | alcohol biosynthetic process | 4 | 11 |
| GO:0046173 | polyol biosynthetic process | 5 | 11 |
| GO:0046174 | polyol catabolic process | 5 | 12 |
| GO:0046434 | organophosphate catabolic process | 4 | 12 |
| GO:0046474 | glycerophospholipid biosynthetic process | 5 | 8 |
| GO:0046486 | glycerolipid metabolic process | 4 | 8 |
| GO:0046488 | phosphatidylinositol metabolic process | 6 | 8 |
| GO:0046838 | obsolete phosphorylated carbohydrate dephosphorylation | 4 | 12 |
| GO:0046854 | phosphatidylinositol phosphate biosynthetic process | 7 | 8 |
| GO:0046855 | obsolete inositol phosphate dephosphorylation | 5 | 12 |
| GO:0071545 | inositol phosphate catabolic process | 5 | 12 |
| GO:0071704 | organic substance metabolic process | 2 | 12 |
| GO:0090407 | organophosphate biosynthetic process | 4 | 8 |
| GO:1901575 | organic substance catabolic process | 3 | 12 |
| GO:1901576 | organic substance biosynthetic process | 3 | 12 |
| GO:1901615 | organic hydroxy compound metabolic process | 3 | 12 |
| GO:1901616 | organic hydroxy compound catabolic process | 4 | 12 |
| GO:1901617 | organic hydroxy compound biosynthetic process | 4 | 11 |
| GO:0007165 | signal transduction | 2 | 1 |
| GO:0050789 | regulation of biological process | 2 | 1 |
| GO:0050794 | regulation of cellular process | 3 | 1 |
| GO:0065007 | biological regulation | 1 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003824 | catalytic activity | 1 | 11 |
| GO:0005488 | binding | 1 | 11 |
| GO:0008934 | inositol monophosphate 1-phosphatase activity | 8 | 11 |
| GO:0016787 | hydrolase activity | 2 | 11 |
| GO:0016788 | hydrolase activity, acting on ester bonds | 3 | 11 |
| GO:0016791 | phosphatase activity | 5 | 11 |
| GO:0042578 | phosphoric ester hydrolase activity | 4 | 11 |
| GO:0043167 | ion binding | 2 | 11 |
| GO:0043169 | cation binding | 3 | 11 |
| GO:0046872 | metal ion binding | 4 | 11 |
| GO:0052745 | inositol phosphate phosphatase activity | 6 | 11 |
| GO:0052832 | inositol monophosphate 3-phosphatase activity | 8 | 11 |
| GO:0052833 | inositol monophosphate 4-phosphatase activity | 8 | 11 |
| GO:0052834 | inositol monophosphate phosphatase activity | 7 | 11 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 177 | 181 | PF00656 | 0.411 |
| CLV_NRD_NRD_1 | 124 | 126 | PF00675 | 0.450 |
| CLV_NRD_NRD_1 | 259 | 261 | PF00675 | 0.410 |
| CLV_PCSK_KEX2_1 | 259 | 261 | PF00082 | 0.413 |
| CLV_PCSK_SKI1_1 | 148 | 152 | PF00082 | 0.423 |
| CLV_PCSK_SKI1_1 | 184 | 188 | PF00082 | 0.455 |
| DOC_CKS1_1 | 1 | 6 | PF01111 | 0.444 |
| DOC_CKS1_1 | 56 | 61 | PF01111 | 0.197 |
| DOC_MAPK_gen_1 | 125 | 132 | PF00069 | 0.450 |
| DOC_MAPK_gen_1 | 62 | 71 | PF00069 | 0.450 |
| DOC_MAPK_MEF2A_6 | 125 | 132 | PF00069 | 0.425 |
| DOC_MAPK_MEF2A_6 | 184 | 193 | PF00069 | 0.197 |
| DOC_MAPK_MEF2A_6 | 272 | 279 | PF00069 | 0.509 |
| DOC_USP7_MATH_1 | 182 | 186 | PF00917 | 0.360 |
| DOC_WW_Pin1_4 | 55 | 60 | PF00397 | 0.197 |
| DOC_WW_Pin1_4 | 73 | 78 | PF00397 | 0.318 |
| LIG_14-3-3_CanoR_1 | 156 | 162 | PF00244 | 0.325 |
| LIG_Actin_WH2_2 | 186 | 204 | PF00022 | 0.197 |
| LIG_BIR_II_1 | 1 | 5 | PF00653 | 0.516 |
| LIG_BIR_III_1 | 1 | 5 | PF00653 | 0.444 |
| LIG_BIR_III_3 | 1 | 5 | PF00653 | 0.598 |
| LIG_BIR_III_4 | 17 | 21 | PF00653 | 0.523 |
| LIG_CtBP_PxDLS_1 | 274 | 280 | PF00389 | 0.406 |
| LIG_deltaCOP1_diTrp_1 | 220 | 230 | PF00928 | 0.423 |
| LIG_FHA_1 | 252 | 258 | PF00498 | 0.248 |
| LIG_FHA_1 | 42 | 48 | PF00498 | 0.391 |
| LIG_FHA_1 | 51 | 57 | PF00498 | 0.281 |
| LIG_FHA_1 | 95 | 101 | PF00498 | 0.313 |
| LIG_FHA_2 | 56 | 62 | PF00498 | 0.318 |
| LIG_FHA_2 | 9 | 15 | PF00498 | 0.494 |
| LIG_LIR_Gen_1 | 140 | 150 | PF02991 | 0.318 |
| LIG_LIR_Gen_1 | 76 | 86 | PF02991 | 0.325 |
| LIG_LIR_Nem_3 | 140 | 145 | PF02991 | 0.318 |
| LIG_LIR_Nem_3 | 76 | 82 | PF02991 | 0.308 |
| LIG_SH2_CRK | 79 | 83 | PF00017 | 0.337 |
| LIG_SH3_3 | 130 | 136 | PF00018 | 0.303 |
| LIG_SUMO_SIM_anti_2 | 167 | 173 | PF11976 | 0.337 |
| LIG_SUMO_SIM_par_1 | 235 | 241 | PF11976 | 0.388 |
| LIG_SUMO_SIM_par_1 | 41 | 49 | PF11976 | 0.220 |
| MOD_CDK_SPxxK_3 | 55 | 62 | PF00069 | 0.197 |
| MOD_CK1_1 | 160 | 166 | PF00069 | 0.272 |
| MOD_CK1_1 | 251 | 257 | PF00069 | 0.414 |
| MOD_CK2_1 | 161 | 167 | PF00069 | 0.264 |
| MOD_CK2_1 | 55 | 61 | PF00069 | 0.432 |
| MOD_CK2_1 | 6 | 12 | PF00069 | 0.497 |
| MOD_DYRK1A_RPxSP_1 | 73 | 77 | PF00069 | 0.388 |
| MOD_GlcNHglycan | 203 | 206 | PF01048 | 0.351 |
| MOD_GlcNHglycan | 250 | 253 | PF01048 | 0.429 |
| MOD_GlcNHglycan | 34 | 37 | PF01048 | 0.415 |
| MOD_GlcNHglycan | 41 | 44 | PF01048 | 0.263 |
| MOD_GlcNHglycan | 82 | 85 | PF01048 | 0.197 |
| MOD_GSK3_1 | 157 | 164 | PF00069 | 0.325 |
| MOD_GSK3_1 | 251 | 258 | PF00069 | 0.328 |
| MOD_GSK3_1 | 264 | 271 | PF00069 | 0.294 |
| MOD_GSK3_1 | 46 | 53 | PF00069 | 0.237 |
| MOD_NEK2_1 | 161 | 166 | PF00069 | 0.335 |
| MOD_NEK2_1 | 201 | 206 | PF00069 | 0.264 |
| MOD_NEK2_1 | 255 | 260 | PF00069 | 0.350 |
| MOD_NEK2_1 | 268 | 273 | PF00069 | 0.286 |
| MOD_PIKK_1 | 3 | 9 | PF00454 | 0.542 |
| MOD_PKA_2 | 201 | 207 | PF00069 | 0.350 |
| MOD_PKA_2 | 39 | 45 | PF00069 | 0.239 |
| MOD_Plk_1 | 275 | 281 | PF00069 | 0.523 |
| MOD_Plk_4 | 128 | 134 | PF00069 | 0.197 |
| MOD_Plk_4 | 165 | 171 | PF00069 | 0.277 |
| MOD_Plk_4 | 94 | 100 | PF00069 | 0.303 |
| MOD_ProDKin_1 | 55 | 61 | PF00069 | 0.197 |
| MOD_ProDKin_1 | 73 | 79 | PF00069 | 0.318 |
| TRG_DiLeu_BaEn_1 | 167 | 172 | PF01217 | 0.272 |
| TRG_DiLeu_BaEn_3 | 66 | 72 | PF01217 | 0.337 |
| TRG_ENDOCYTIC_2 | 79 | 82 | PF00928 | 0.308 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0F6B4W4 | Salmonella typhimurium (strain 14028s / SGSC 2262) | 30% | 100% |
| A0A0N0P7R4 | Leptomonas seymouri | 61% | 98% |
| A0A0S4J704 | Bodo saltans | 44% | 99% |
| A0A0S4J9K7 | Bodo saltans | 38% | 89% |
| A0A1X0NSL5 | Trypanosomatidae | 48% | 97% |
| A0A1X0NTZ6 | Trypanosomatidae | 33% | 74% |
| A0A3R7LSW3 | Trypanosoma rangeli | 56% | 100% |
| A0A3S7WUM5 | Leishmania donovani | 79% | 98% |
| A0A422NRH4 | Trypanosoma rangeli | 29% | 78% |
| A4HXL7 | Leishmania infantum | 79% | 98% |
| B4ED80 | Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) | 34% | 100% |
| C9ZPB2 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 50% | 100% |
| C9ZXW3 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 34% | 77% |
| E9ARB3 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 80% | 98% |
| O14732 | Homo sapiens | 33% | 98% |
| O33832 | Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) | 37% | 100% |
| O49071 | Mesembryanthemum crystallinum | 39% | 100% |
| O53907 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | 30% | 100% |
| O55023 | Mus musculus | 30% | 100% |
| O67791 | Aquifex aeolicus (strain VF5) | 30% | 100% |
| O77591 | Sus scrofa | 32% | 100% |
| P0ADG4 | Escherichia coli (strain K12) | 30% | 100% |
| P0ADG5 | Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) | 30% | 100% |
| P0ADG6 | Escherichia coli O157:H7 | 30% | 100% |
| P11634 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 28% | 83% |
| P20456 | Bos taurus | 34% | 100% |
| P25416 | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) | 27% | 85% |
| P29218 | Homo sapiens | 34% | 100% |
| P29219 | Xenopus laevis | 32% | 99% |
| P29785 | Streptomyces griseus | 26% | 100% |
| P38710 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 28% | 96% |
| P44333 | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) | 30% | 100% |
| P46813 | Mycobacterium leprae (strain TN) | 28% | 97% |
| P54926 | Solanum lycopersicum | 37% | 100% |
| P54927 | Solanum lycopersicum | 43% | 100% |
| P54928 | Solanum lycopersicum | 36% | 100% |
| P56160 | Chlorobaculum parvum (strain DSM 263 / NCIMB 8327) | 31% | 100% |
| P58537 | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) | 30% | 100% |
| P65166 | Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) | 32% | 97% |
| P74158 | Synechocystis sp. (strain PCC 6803 / Kazusa) | 37% | 98% |
| P95189 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | 32% | 100% |
| P97697 | Rattus norvegicus | 29% | 100% |
| P9WKI8 | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) | 32% | 97% |
| P9WKI9 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | 32% | 97% |
| Q05533 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 35% | 97% |
| Q19420 | Caenorhabditis elegans | 30% | 99% |
| Q45499 | Bacillus subtilis (strain 168) | 28% | 100% |
| Q4QE50 | Leishmania major | 78% | 100% |
| Q54U72 | Dictyostelium discoideum | 39% | 100% |
| Q5R4X0 | Pongo abelii | 34% | 100% |
| Q6NPM8 | Arabidopsis thaliana | 26% | 82% |
| Q87BG1 | Xylella fastidiosa (strain Temecula1 / ATCC 700964) | 33% | 100% |
| Q89AK9 | Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) | 26% | 100% |
| Q8CIN7 | Rattus norvegicus | 33% | 97% |
| Q8NS80 | Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) | 30% | 100% |
| Q91UZ5 | Mus musculus | 33% | 97% |
| Q92M71 | Rhizobium meliloti (strain 1021) | 35% | 100% |
| Q94F00 | Arabidopsis thaliana | 33% | 76% |
| Q98F59 | Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) | 34% | 100% |
| Q9A3D5 | Caulobacter vibrioides (strain ATCC 19089 / CB15) | 30% | 100% |
| Q9CNV8 | Pasteurella multocida (strain Pm70) | 31% | 100% |
| Q9HXI4 | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 34% | 100% |
| Q9JU03 | Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491) | 31% | 100% |
| Q9JZ07 | Neisseria meningitidis serogroup B (strain MC58) | 31% | 100% |
| Q9K4B1 | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) | 30% | 100% |
| Q9KTY5 | Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) | 31% | 100% |
| Q9M8S8 | Arabidopsis thaliana | 41% | 100% |
| Q9PAM0 | Xylella fastidiosa (strain 9a5c) | 34% | 100% |
| V5B4K7 | Trypanosoma cruzi | 35% | 78% |
| V5BJH0 | Trypanosoma cruzi | 54% | 100% |