Putative DNAJ domain protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNAJ domain protein, putative

Species:

Leishmania braziliensis

UniProt:

A4H933_LEIBR

TriTrypDb:

LbrM.17.0890 , LBRM2903_170015500

Length:

587

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H933

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H933

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	323	327	PF00656	0.511
CLV_C14_Caspase3-7	566	570	PF00656	0.606
CLV_NRD_NRD_1	200	202	PF00675	0.534
CLV_NRD_NRD_1	206	208	PF00675	0.570
CLV_NRD_NRD_1	281	283	PF00675	0.432
CLV_NRD_NRD_1	437	439	PF00675	0.602
CLV_NRD_NRD_1	55	57	PF00675	0.382
CLV_PCSK_KEX2_1	106	108	PF00082	0.681
CLV_PCSK_KEX2_1	206	208	PF00082	0.714
CLV_PCSK_KEX2_1	259	261	PF00082	0.522
CLV_PCSK_KEX2_1	268	270	PF00082	0.553
CLV_PCSK_KEX2_1	280	282	PF00082	0.480
CLV_PCSK_KEX2_1	437	439	PF00082	0.602
CLV_PCSK_KEX2_1	55	57	PF00082	0.282
CLV_PCSK_PC1ET2_1	106	108	PF00082	0.681
CLV_PCSK_PC1ET2_1	259	261	PF00082	0.522
CLV_PCSK_PC1ET2_1	268	270	PF00082	0.553
CLV_PCSK_PC1ET2_1	280	282	PF00082	0.480
CLV_PCSK_PC7_1	264	270	PF00082	0.584
CLV_PCSK_SKI1_1	103	107	PF00082	0.640
CLV_PCSK_SKI1_1	177	181	PF00082	0.537
CLV_PCSK_SKI1_1	254	258	PF00082	0.481
CLV_PCSK_SKI1_1	264	268	PF00082	0.486
CLV_PCSK_SKI1_1	56	60	PF00082	0.414
CLV_Separin_Metazoa	315	319	PF03568	0.439
CLV_Separin_Metazoa	365	369	PF03568	0.741
DEG_SPOP_SBC_1	346	350	PF00917	0.546
DOC_MAPK_DCC_7	308	316	PF00069	0.424
DOC_MAPK_MEF2A_6	308	316	PF00069	0.424
DOC_MAPK_MEF2A_6	65	73	PF00069	0.293
DOC_MAPK_RevD_3	493	508	PF00069	0.587
DOC_MIT_MIM_1	287	295	PF04212	0.403
DOC_PP4_FxxP_1	105	108	PF00568	0.674
DOC_USP7_MATH_1	132	136	PF00917	0.623
DOC_USP7_MATH_1	181	185	PF00917	0.593
DOC_USP7_MATH_1	186	190	PF00917	0.545
DOC_USP7_MATH_1	213	217	PF00917	0.764
DOC_USP7_MATH_1	218	222	PF00917	0.839
DOC_USP7_MATH_1	23	27	PF00917	0.615
DOC_USP7_MATH_1	232	236	PF00917	0.665
DOC_USP7_MATH_1	245	249	PF00917	0.667
DOC_USP7_MATH_1	355	359	PF00917	0.679
DOC_USP7_MATH_1	431	435	PF00917	0.632
DOC_USP7_MATH_1	471	475	PF00917	0.670
DOC_USP7_MATH_1	554	558	PF00917	0.665
DOC_USP7_MATH_2	571	577	PF00917	0.567
DOC_USP7_UBL2_3	508	512	PF12436	0.617
DOC_WW_Pin1_4	209	214	PF00397	0.575
DOC_WW_Pin1_4	307	312	PF00397	0.468
DOC_WW_Pin1_4	321	326	PF00397	0.600
DOC_WW_Pin1_4	413	418	PF00397	0.629
DOC_WW_Pin1_4	460	465	PF00397	0.691
DOC_WW_Pin1_4	474	479	PF00397	0.621
DOC_WW_Pin1_4	532	537	PF00397	0.618
DOC_WW_Pin1_4	543	548	PF00397	0.591
DOC_WW_Pin1_4	558	563	PF00397	0.647
DOC_WW_Pin1_4	582	587	PF00397	0.586
LIG_14-3-3_CanoR_1	206	211	PF00244	0.706
LIG_14-3-3_CanoR_1	28	38	PF00244	0.587
LIG_14-3-3_CanoR_1	291	296	PF00244	0.459
LIG_14-3-3_CanoR_1	423	433	PF00244	0.607
LIG_14-3-3_CanoR_1	527	537	PF00244	0.605
LIG_14-3-3_CanoR_1	564	574	PF00244	0.597
LIG_Actin_WH2_2	186	203	PF00022	0.486
LIG_Actin_WH2_2	292	310	PF00022	0.435
LIG_BIR_III_2	22	26	PF00653	0.595
LIG_BRCT_BRCA1_1	175	179	PF00533	0.505
LIG_BRCT_BRCA1_1	262	266	PF00533	0.434
LIG_BRCT_BRCA1_2	262	268	PF00533	0.437
LIG_deltaCOP1_diTrp_1	287	292	PF00928	0.550
LIG_eIF4E_1	54	60	PF01652	0.413
LIG_FHA_1	346	352	PF00498	0.609
LIG_FHA_1	42	48	PF00498	0.417
LIG_FHA_1	425	431	PF00498	0.598
LIG_FHA_1	451	457	PF00498	0.667
LIG_FHA_1	490	496	PF00498	0.607
LIG_FHA_2	32	38	PF00498	0.407
LIG_FHA_2	321	327	PF00498	0.497
LIG_FHA_2	44	50	PF00498	0.551
LIG_GSK3_LRP6_1	582	587	PF00069	0.564
LIG_LIR_Apic_2	349	355	PF02991	0.674
LIG_LIR_Gen_1	287	297	PF02991	0.392
LIG_LIR_Gen_1	33	41	PF02991	0.431
LIG_LIR_Gen_1	90	100	PF02991	0.455
LIG_LIR_Nem_3	124	130	PF02991	0.619
LIG_LIR_Nem_3	163	169	PF02991	0.465
LIG_LIR_Nem_3	287	292	PF02991	0.550
LIG_LIR_Nem_3	33	39	PF02991	0.469
LIG_LIR_Nem_3	51	57	PF02991	0.355
LIG_LIR_Nem_3	90	95	PF02991	0.314
LIG_MYND_1	467	471	PF01753	0.606
LIG_SH2_CRK	119	123	PF00017	0.619
LIG_SH2_CRK	36	40	PF00017	0.442
LIG_SH2_CRK	54	58	PF00017	0.286
LIG_SH2_CRK	92	96	PF00017	0.547
LIG_SH2_NCK_1	322	326	PF00017	0.493
LIG_SH2_STAP1	119	123	PF00017	0.619
LIG_SH2_STAP1	128	132	PF00017	0.519
LIG_SH2_STAP1	174	178	PF00017	0.401
LIG_SH2_STAP1	92	96	PF00017	0.547
LIG_SH2_STAT3	283	286	PF00017	0.512
LIG_SH2_STAT5	283	286	PF00017	0.512
LIG_SH2_STAT5	322	325	PF00017	0.497
LIG_SH3_1	580	586	PF00018	0.654
LIG_SH3_3	111	117	PF00018	0.653
LIG_SH3_3	427	433	PF00018	0.604
LIG_SH3_3	461	467	PF00018	0.674
LIG_SH3_3	478	484	PF00018	0.588
LIG_SH3_3	57	63	PF00018	0.553
LIG_SH3_3	578	584	PF00018	0.657
LIG_SUMO_SIM_par_1	551	558	PF11976	0.598
LIG_TRAF2_1	46	49	PF00917	0.545
LIG_TRAF2_1	541	544	PF00917	0.598
MOD_CDC14_SPxK_1	561	564	PF00782	0.682
MOD_CDK_SPK_2	582	587	PF00069	0.564
MOD_CDK_SPxK_1	558	564	PF00069	0.684
MOD_CDK_SPxxK_3	479	486	PF00069	0.630
MOD_CK1_1	209	215	PF00069	0.720
MOD_CK1_1	216	222	PF00069	0.706
MOD_CK1_1	235	241	PF00069	0.703
MOD_CK1_1	26	32	PF00069	0.732
MOD_CK1_1	345	351	PF00069	0.600
MOD_CK1_1	393	399	PF00069	0.820
MOD_CK1_1	4	10	PF00069	0.583
MOD_CK1_1	401	407	PF00069	0.788
MOD_CK1_1	413	419	PF00069	0.611
MOD_CK1_1	450	456	PF00069	0.681
MOD_CK1_1	474	480	PF00069	0.667
MOD_CK1_1	496	502	PF00069	0.672
MOD_CK1_1	528	534	PF00069	0.615
MOD_CK2_1	359	365	PF00069	0.659
MOD_CK2_1	43	49	PF00069	0.577
MOD_CK2_1	470	476	PF00069	0.713
MOD_CK2_1	537	543	PF00069	0.585
MOD_CK2_1	81	87	PF00069	0.293
MOD_GlcNHglycan	16	19	PF01048	0.671
MOD_GlcNHglycan	169	172	PF01048	0.625
MOD_GlcNHglycan	221	224	PF01048	0.827
MOD_GlcNHglycan	228	231	PF01048	0.726
MOD_GlcNHglycan	234	237	PF01048	0.637
MOD_GlcNHglycan	28	31	PF01048	0.562
MOD_GlcNHglycan	369	372	PF01048	0.614
MOD_GlcNHglycan	395	398	PF01048	0.861
MOD_GlcNHglycan	449	452	PF01048	0.740
MOD_GlcNHglycan	513	516	PF01048	0.628
MOD_GlcNHglycan	527	530	PF01048	0.693
MOD_GlcNHglycan	539	542	PF01048	0.618
MOD_GlcNHglycan	66	69	PF01048	0.364
MOD_GlcNHglycan	83	86	PF01048	0.254
MOD_GlcNHglycan	96	99	PF01048	0.431
MOD_GSK3_1	181	188	PF00069	0.607
MOD_GSK3_1	205	212	PF00069	0.799
MOD_GSK3_1	321	328	PF00069	0.598
MOD_GSK3_1	329	336	PF00069	0.708
MOD_GSK3_1	342	349	PF00069	0.569
MOD_GSK3_1	355	362	PF00069	0.567
MOD_GSK3_1	367	374	PF00069	0.606
MOD_GSK3_1	39	46	PF00069	0.509
MOD_GSK3_1	403	410	PF00069	0.741
MOD_GSK3_1	470	477	PF00069	0.687
MOD_GSK3_1	485	492	PF00069	0.620
MOD_GSK3_1	528	535	PF00069	0.635
MOD_GSK3_1	554	561	PF00069	0.661
MOD_GSK3_1	81	88	PF00069	0.293
MOD_N-GLC_1	245	250	PF02516	0.493
MOD_N-GLC_1	39	44	PF02516	0.435
MOD_NEK2_1	137	142	PF00069	0.588
MOD_NEK2_1	165	170	PF00069	0.425
MOD_NEK2_1	185	190	PF00069	0.618
MOD_NEK2_1	193	198	PF00069	0.549
MOD_NEK2_1	205	210	PF00069	0.630
MOD_NEK2_1	320	325	PF00069	0.492
MOD_NEK2_1	347	352	PF00069	0.631
MOD_NEK2_1	367	372	PF00069	0.608
MOD_NEK2_1	39	44	PF00069	0.435
MOD_NEK2_1	407	412	PF00069	0.708
MOD_NEK2_2	403	408	PF00069	0.609
MOD_PIKK_1	23	29	PF00454	0.585
MOD_PIKK_1	334	340	PF00454	0.566
MOD_PIKK_1	407	413	PF00454	0.679
MOD_PIKK_1	455	461	PF00454	0.611
MOD_PKA_1	206	212	PF00069	0.715
MOD_PKA_2	205	211	PF00069	0.703
MOD_PKA_2	219	225	PF00069	0.621
MOD_PKA_2	290	296	PF00069	0.460
MOD_PKA_2	355	361	PF00069	0.544
MOD_PKA_2	367	373	PF00069	0.578
MOD_PKA_2	393	399	PF00069	0.611
MOD_PKA_2	407	413	PF00069	0.634
MOD_PKA_2	485	491	PF00069	0.625
MOD_PKA_2	496	502	PF00069	0.560
MOD_PKA_2	563	569	PF00069	0.610
MOD_PKA_2	64	70	PF00069	0.293
MOD_Plk_1	325	331	PF00069	0.553
MOD_Plk_2-3	359	365	PF00069	0.640
MOD_Plk_2-3	573	579	PF00069	0.584
MOD_Plk_4	110	116	PF00069	0.663
MOD_Plk_4	152	158	PF00069	0.519
MOD_Plk_4	298	304	PF00069	0.392
MOD_Plk_4	31	37	PF00069	0.672
MOD_Plk_4	342	348	PF00069	0.650
MOD_Plk_4	548	554	PF00069	0.594
MOD_ProDKin_1	209	215	PF00069	0.578
MOD_ProDKin_1	307	313	PF00069	0.468
MOD_ProDKin_1	321	327	PF00069	0.608
MOD_ProDKin_1	413	419	PF00069	0.630
MOD_ProDKin_1	460	466	PF00069	0.688
MOD_ProDKin_1	474	480	PF00069	0.623
MOD_ProDKin_1	532	538	PF00069	0.612
MOD_ProDKin_1	543	549	PF00069	0.593
MOD_ProDKin_1	558	564	PF00069	0.651
MOD_SUMO_for_1	258	261	PF00179	0.433
MOD_SUMO_rev_2	573	581	PF00179	0.648
TRG_DiLeu_BaEn_1	152	157	PF01217	0.378
TRG_DiLeu_BaEn_1	315	320	PF01217	0.437
TRG_ENDOCYTIC_2	119	122	PF00928	0.603
TRG_ENDOCYTIC_2	166	169	PF00928	0.506
TRG_ENDOCYTIC_2	36	39	PF00928	0.435
TRG_ENDOCYTIC_2	54	57	PF00928	0.268
TRG_ENDOCYTIC_2	80	83	PF00928	0.435
TRG_ENDOCYTIC_2	92	95	PF00928	0.421
TRG_ER_diArg_1	205	207	PF00400	0.579
TRG_ER_diArg_1	281	283	PF00400	0.432
TRG_ER_diArg_1	379	382	PF00400	0.621
TRG_ER_diArg_1	436	438	PF00400	0.601
TRG_ER_diArg_1	54	56	PF00400	0.282
TRG_NES_CRM1_1	286	300	PF08389	0.400
TRG_Pf-PMV_PEXEL_1	282	286	PF00026	0.425

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X3L8	Leishmania donovani	56%	79%
A4I5K6	Leishmania infantum	55%	79%
E9B0V1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	51%	79%
Q4Q7B5	Leishmania major	61%	100%