GMP reductase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

GMP reductase

Gene product:

GMP reductase

Species:

Leishmania braziliensis

UniProt:

A4H923_LEIBR

TriTrypDb:

LbrM.17.0790 , LBRM2903_170014700

Length:

492

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	12
GO:0032991	protein-containing complex	1	8
GO:0110165	cellular anatomical entity	1	12
GO:1902494	catalytic complex	2	8
GO:1902560	GMP reductase complex	4	8
GO:1990204	oxidoreductase complex	3	8
GO:0005730	nucleolus	5	1
GO:0005777	peroxisome	6	1
GO:0020015	glycosome	7	1
GO:0042579	microbody	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1

Expansion

Sequence features

A4H923

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H923

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006144	purine nucleobase metabolic process	5	8
GO:0006163	purine nucleotide metabolic process	5	12
GO:0006164	purine nucleotide biosynthetic process	6	12
GO:0006177	GMP biosynthetic process	8	11
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006753	nucleoside phosphate metabolic process	4	12
GO:0006793	phosphorus metabolic process	3	12
GO:0006796	phosphate-containing compound metabolic process	4	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009058	biosynthetic process	2	12
GO:0009112	nucleobase metabolic process	4	8
GO:0009117	nucleotide metabolic process	5	12
GO:0009123	nucleoside monophosphate metabolic process	5	11
GO:0009124	nucleoside monophosphate biosynthetic process	6	11
GO:0009126	purine nucleoside monophosphate metabolic process	6	11
GO:0009127	purine nucleoside monophosphate biosynthetic process	7	11
GO:0009150	purine ribonucleotide metabolic process	6	12
GO:0009152	purine ribonucleotide biosynthetic process	7	12
GO:0009156	ribonucleoside monophosphate biosynthetic process	7	11
GO:0009161	ribonucleoside monophosphate metabolic process	6	11
GO:0009165	nucleotide biosynthetic process	6	12
GO:0009167	purine ribonucleoside monophosphate metabolic process	7	11
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	8	11
GO:0009259	ribonucleotide metabolic process	5	12
GO:0009260	ribonucleotide biosynthetic process	6	12
GO:0009987	cellular process	1	12
GO:0018130	heterocycle biosynthetic process	4	12
GO:0019438	aromatic compound biosynthetic process	4	12
GO:0019637	organophosphate metabolic process	3	12
GO:0019693	ribose phosphate metabolic process	4	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0034654	nucleobase-containing compound biosynthetic process	4	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044249	cellular biosynthetic process	3	12
GO:0044271	cellular nitrogen compound biosynthetic process	4	12
GO:0044281	small molecule metabolic process	2	12
GO:0046037	GMP metabolic process	7	11
GO:0046390	ribose phosphate biosynthetic process	5	12
GO:0046483	heterocycle metabolic process	3	12
GO:0055086	nucleobase-containing small molecule metabolic process	3	12
GO:0071704	organic substance metabolic process	2	12
GO:0072521	purine-containing compound metabolic process	4	12
GO:0072522	purine-containing compound biosynthetic process	5	12
GO:0090407	organophosphate biosynthetic process	4	12
GO:1901135	carbohydrate derivative metabolic process	3	12
GO:1901137	carbohydrate derivative biosynthetic process	4	12
GO:1901293	nucleoside phosphate biosynthetic process	5	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:1901362	organic cyclic compound biosynthetic process	4	12
GO:1901564	organonitrogen compound metabolic process	3	12
GO:1901566	organonitrogen compound biosynthetic process	4	12
GO:1901576	organic substance biosynthetic process	3	12
GO:0006183	GTP biosynthetic process	8	1
GO:0009141	nucleoside triphosphate metabolic process	5	1
GO:0009142	nucleoside triphosphate biosynthetic process	6	1
GO:0009144	purine nucleoside triphosphate metabolic process	6	1
GO:0009145	purine nucleoside triphosphate biosynthetic process	7	1
GO:0009199	ribonucleoside triphosphate metabolic process	6	1
GO:0009201	ribonucleoside triphosphate biosynthetic process	7	1
GO:0009205	purine ribonucleoside triphosphate metabolic process	7	1
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	8	1
GO:0046039	GTP metabolic process	7	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	12
GO:0003920	GMP reductase activity	5	8
GO:0003938	IMP dehydrogenase activity	5	12
GO:0005488	binding	1	12
GO:0016491	oxidoreductase activity	2	12
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	3	12
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4	12
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3	8
GO:0043167	ion binding	2	12
GO:0043169	cation binding	3	12
GO:0046857	oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor	4	8
GO:0046872	metal ion binding	4	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	300	304	PF00656	0.550
CLV_NRD_NRD_1	123	125	PF00675	0.254
CLV_NRD_NRD_1	140	142	PF00675	0.206
CLV_NRD_NRD_1	30	32	PF00675	0.245
CLV_NRD_NRD_1	89	91	PF00675	0.306
CLV_PCSK_FUR_1	414	418	PF00082	0.320
CLV_PCSK_KEX2_1	140	142	PF00082	0.331
CLV_PCSK_KEX2_1	168	170	PF00082	0.170
CLV_PCSK_KEX2_1	190	192	PF00082	0.308
CLV_PCSK_KEX2_1	244	246	PF00082	0.334
CLV_PCSK_KEX2_1	416	418	PF00082	0.293
CLV_PCSK_KEX2_1	93	95	PF00082	0.245
CLV_PCSK_PC1ET2_1	168	170	PF00082	0.170
CLV_PCSK_PC1ET2_1	190	192	PF00082	0.331
CLV_PCSK_PC1ET2_1	244	246	PF00082	0.334
CLV_PCSK_PC1ET2_1	416	418	PF00082	0.293
CLV_PCSK_PC1ET2_1	93	95	PF00082	0.245
CLV_PCSK_SKI1_1	104	108	PF00082	0.242
CLV_PCSK_SKI1_1	220	224	PF00082	0.281
CLV_PCSK_SKI1_1	274	278	PF00082	0.239
CLV_PCSK_SKI1_1	340	344	PF00082	0.331
CLV_PCSK_SKI1_1	394	398	PF00082	0.257
CLV_PCSK_SKI1_1	90	94	PF00082	0.281
DEG_SPOP_SBC_1	34	38	PF00917	0.509
DOC_ANK_TNKS_1	68	75	PF00023	0.445
DOC_CDC14_PxL_1	4	12	PF14671	0.622
DOC_CKS1_1	163	168	PF01111	0.445
DOC_CYCLIN_yCln2_LP_2	46	52	PF00134	0.457
DOC_MAPK_gen_1	190	197	PF00069	0.446
DOC_MAPK_gen_1	42	50	PF00069	0.370
DOC_MAPK_MEF2A_6	42	50	PF00069	0.370
DOC_MAPK_RevD_3	19	32	PF00069	0.450
DOC_PP2B_LxvP_1	20	23	PF13499	0.445
DOC_PP2B_LxvP_1	46	49	PF13499	0.457
DOC_USP7_MATH_1	154	158	PF00917	0.507
DOC_USP7_MATH_1	27	31	PF00917	0.444
DOC_USP7_UBL2_3	391	395	PF12436	0.445
DOC_WW_Pin1_4	162	167	PF00397	0.436
DOC_WW_Pin1_4	23	28	PF00397	0.470
LIG_14-3-3_CanoR_1	169	178	PF00244	0.462
LIG_14-3-3_CanoR_1	220	225	PF00244	0.489
LIG_14-3-3_CanoR_1	453	459	PF00244	0.445
LIG_14-3-3_CanoR_1	94	99	PF00244	0.464
LIG_Actin_WH2_2	200	217	PF00022	0.531
LIG_Actin_WH2_2	469	484	PF00022	0.457
LIG_BIR_II_1	1	5	PF00653	0.575
LIG_Clathr_ClatBox_1	131	135	PF01394	0.457
LIG_eIF4E_1	16	22	PF01652	0.457
LIG_FHA_1	111	117	PF00498	0.370
LIG_FHA_1	190	196	PF00498	0.455
LIG_FHA_1	280	286	PF00498	0.455
LIG_FHA_1	319	325	PF00498	0.438
LIG_FHA_1	369	375	PF00498	0.445
LIG_FHA_2	109	115	PF00498	0.457
LIG_FHA_2	13	19	PF00498	0.429
LIG_FHA_2	177	183	PF00498	0.469
LIG_FHA_2	207	213	PF00498	0.445
LIG_FHA_2	355	361	PF00498	0.470
LIG_FHA_2	55	61	PF00498	0.445
LIG_LIR_Gen_1	15	23	PF02991	0.445
LIG_LIR_Gen_1	420	431	PF02991	0.437
LIG_LIR_LC3C_4	255	259	PF02991	0.457
LIG_LIR_Nem_3	15	19	PF02991	0.445
LIG_LIR_Nem_3	420	426	PF02991	0.488
LIG_MYND_1	196	200	PF01753	0.531
LIG_PDZ_Class_1	487	492	PF00595	0.527
LIG_SH2_SRC	16	19	PF00017	0.445
LIG_SH2_STAP1	16	20	PF00017	0.445
LIG_SH2_STAT5	206	209	PF00017	0.457
LIG_SH2_STAT5	458	461	PF00017	0.457
LIG_SH3_3	437	443	PF00018	0.445
LIG_SH3_3	5	11	PF00018	0.596
LIG_SUMO_SIM_anti_2	129	136	PF11976	0.487
LIG_SUMO_SIM_anti_2	17	23	PF11976	0.445
LIG_SUMO_SIM_anti_2	255	260	PF11976	0.440
LIG_SUMO_SIM_par_1	255	260	PF11976	0.445
LIG_TRAF2_1	115	118	PF00917	0.498
LIG_TRAF2_1	179	182	PF00917	0.457
LIG_TRAF2_1	81	84	PF00917	0.486
LIG_TYR_ITIM	14	19	PF00017	0.445
LIG_UBA3_1	159	168	PF00899	0.524
LIG_UBA3_1	186	190	PF00899	0.370
MOD_CDC14_SPxK_1	26	29	PF00782	0.470
MOD_CDK_SPxK_1	162	168	PF00069	0.466
MOD_CDK_SPxK_1	23	29	PF00069	0.470
MOD_CDK_SPxxK_3	162	169	PF00069	0.457
MOD_CK1_1	108	114	PF00069	0.499
MOD_CK1_1	173	179	PF00069	0.479
MOD_CK1_1	454	460	PF00069	0.445
MOD_CK2_1	108	114	PF00069	0.457
MOD_CK2_1	176	182	PF00069	0.451
MOD_CK2_1	407	413	PF00069	0.445
MOD_CK2_1	460	466	PF00069	0.374
MOD_CK2_1	54	60	PF00069	0.445
MOD_CK2_1	78	84	PF00069	0.445
MOD_Cter_Amidation	122	125	PF01082	0.257
MOD_Cter_Amidation	392	395	PF01082	0.257
MOD_GlcNHglycan	108	111	PF01048	0.323
MOD_GlcNHglycan	121	124	PF01048	0.331
MOD_GlcNHglycan	332	335	PF01048	0.243
MOD_GlcNHglycan	453	456	PF01048	0.243
MOD_GlcNHglycan	476	479	PF01048	0.277
MOD_GlcNHglycan	483	486	PF01048	0.231
MOD_GSK3_1	106	113	PF00069	0.424
MOD_GSK3_1	170	177	PF00069	0.485
MOD_GSK3_1	23	30	PF00069	0.442
MOD_GSK3_1	314	321	PF00069	0.445
MOD_GSK3_1	34	41	PF00069	0.427
MOD_GSK3_1	483	490	PF00069	0.463
MOD_GSK3_1	50	57	PF00069	0.445
MOD_N-GLC_1	119	124	PF02516	0.357
MOD_N-GLC_1	174	179	PF02516	0.266
MOD_N-GLC_1	220	225	PF02516	0.308
MOD_N-GLC_1	34	39	PF02516	0.323
MOD_N-GLC_1	407	412	PF02516	0.245
MOD_NEK2_1	105	110	PF00069	0.406
MOD_NEK2_1	119	124	PF00069	0.506
MOD_NEK2_1	159	164	PF00069	0.487
MOD_NEK2_1	170	175	PF00069	0.408
MOD_NEK2_1	189	194	PF00069	0.479
MOD_NEK2_1	214	219	PF00069	0.550
MOD_NEK2_1	481	486	PF00069	0.451
MOD_PIKK_1	206	212	PF00454	0.556
MOD_PK_1	78	84	PF00069	0.457
MOD_PKA_2	474	480	PF00069	0.462
MOD_PKA_2	481	487	PF00069	0.465
MOD_Plk_1	174	180	PF00069	0.464
MOD_Plk_1	220	226	PF00069	0.503
MOD_Plk_1	60	66	PF00069	0.557
MOD_Plk_4	159	165	PF00069	0.486
MOD_Plk_4	368	374	PF00069	0.445
MOD_Plk_4	94	100	PF00069	0.445
MOD_ProDKin_1	162	168	PF00069	0.436
MOD_ProDKin_1	23	29	PF00069	0.470
MOD_SUMO_for_1	200	203	PF00179	0.531
MOD_SUMO_for_1	238	241	PF00179	0.506
MOD_SUMO_rev_2	241	246	PF00179	0.481
MOD_SUMO_rev_2	56	64	PF00179	0.531
TRG_DiLeu_BaEn_1	182	187	PF01217	0.400
TRG_DiLeu_BaEn_1	203	208	PF01217	0.486
TRG_DiLeu_BaEn_3	83	89	PF01217	0.506
TRG_DiLeu_BaLyEn_6	193	198	PF01217	0.550
TRG_DiLeu_BaLyEn_6	226	231	PF01217	0.437
TRG_ENDOCYTIC_2	16	19	PF00928	0.445
TRG_ER_diArg_1	140	142	PF00400	0.531
TRG_ER_diArg_1	227	230	PF00400	0.457
TRG_ER_diArg_1	28	31	PF00400	0.457
TRG_NLS_MonoExtC_3	89	94	PF00514	0.506
TRG_NLS_MonoExtN_4	391	398	PF00514	0.457
TRG_Pf-PMV_PEXEL_1	387	392	PF00026	0.245
TRG_Pf-PMV_PEXEL_1	416	420	PF00026	0.313
TRG_PTS1	489	492	PF00515	0.523

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0B5L585	Penicillium brevicompactum	35%	90%
A0A0N0P602	Leptomonas seymouri	86%	100%
A0A0N1I2L9	Leptomonas seymouri	37%	96%
A0A0S4ISB5	Bodo saltans	35%	96%
A0A0S4KKC7	Bodo saltans	74%	90%
A0A1X0NTH3	Trypanosomatidae	77%	100%
A0A1X0P5Z8	Trypanosomatidae	36%	96%
A0A3Q8IBE3	Leishmania donovani	35%	96%
A0A3R7MPJ5	Trypanosoma rangeli	39%	96%
A0A3S7WUI0	Leishmania donovani	94%	100%
A0A422N4U4	Trypanosoma rangeli	72%	100%
A0JNA3	Bos taurus	36%	96%
A0QYE8	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	32%	100%
A1JJK8	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	31%	100%
A4HAA5	Leishmania braziliensis	35%	96%
A4HXF5	Leishmania infantum	94%	100%
A4HYI5	Leishmania infantum	35%	96%
A4TPS6	Yersinia pestis (strain Pestoides F)	31%	100%
A7FM52	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	31%	100%
A9A5Y7	Nitrosopumilus maritimus (strain SCM1)	49%	100%
A9MQA3	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	31%	100%
A9MZN3	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	31%	100%
A9R1J4	Yersinia pestis bv. Antiqua (strain Angola)	31%	100%
B0UXP9	Danio rerio	36%	96%
B1JK64	Yersinia pseudotuberculosis serotype O:3 (strain YPIII)	31%	100%
B1L5U5	Korarchaeum cryptofilum (strain OPF8)	38%	100%
B2K4G3	Yersinia pseudotuberculosis serotype IB (strain PB1/+)	31%	100%
B4SU63	Salmonella newport (strain SL254)	31%	100%
B4TJA0	Salmonella heidelberg (strain SL476)	31%	100%
B4TXJ0	Salmonella schwarzengrund (strain CVM19633)	31%	100%
B5BLD7	Salmonella paratyphi A (strain AKU_12601)	31%	100%
B5F7X8	Salmonella agona (strain SL483)	31%	100%
B5FI86	Salmonella dublin (strain CT_02021853)	31%	100%
B5R2N9	Salmonella enteritidis PT4 (strain P125109)	31%	100%
B5RH79	Salmonella gallinarum (strain 287/91 / NCTC 13346)	31%	100%
B5Y1T3	Klebsiella pneumoniae (strain 342)	31%	100%
C9ZP27	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	100%
D0A0V8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	96%
D3ZLZ7	Rattus norvegicus	36%	96%
E9AR50	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E9ASA9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	96%
E9BDA8	Leishmania donovani (strain BPK282A1)	94%	100%
E9PU28	Rattus norvegicus	36%	96%
F1DBB2	Penicillium brevicompactum	36%	93%
F6S675	Xenopus tropicalis	37%	96%
F7CYY5	Xenopus tropicalis	36%	96%
O00086	Candida albicans	37%	94%
O14344	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	94%
O32912	Mycobacterium leprae (strain TN)	33%	100%
O50316	Chlorobaculum parvum (strain DSM 263 / NCIMB 8327)	43%	100%
O58045	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	45%	100%
O67820	Aquifex aeolicus (strain VF5)	48%	100%
P0ADG7	Escherichia coli (strain K12)	42%	100%
P0ADG8	Escherichia coli O157:H7	42%	100%
P0ADG9	Shigella flexneri	42%	100%
P0C0H6	Streptococcus pyogenes	45%	100%
P0C0H7	Streptococcus pyogenes serotype M1	45%	100%
P0DB88	Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)	45%	100%
P0DB89	Streptococcus pyogenes serotype M3 (strain SSI-1)	45%	100%
P12268	Homo sapiens	36%	96%
P12269	Cricetulus griseus	36%	96%
P20839	Homo sapiens	36%	96%
P21620	Leishmania donovani	35%	96%
P21879	Bacillus subtilis (strain 168)	44%	100%
P24547	Mus musculus	35%	96%
P31002	Acinetobacter calcoaceticus	42%	100%
P38697	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	94%
P39567	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	100%
P42851	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	45%	100%
P44334	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	44%	100%
P47996	Arabidopsis thaliana	33%	98%
P50094	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	94%
P50095	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	94%
P50096	Mus musculus	36%	96%
P50097	Tritrichomonas foetus	31%	98%
P50098	Trypanosoma brucei brucei	36%	96%
P56088	Helicobacter pylori (strain ATCC 700392 / 26695)	45%	100%
P65168	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	43%	93%
P65169	Staphylococcus aureus (strain Mu50 / ATCC 700699)	45%	100%
P65173	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	32%	100%
P68839	Streptococcus pyogenes serotype M18 (strain MGAS8232)	45%	100%
P99106	Staphylococcus aureus (strain N315)	45%	100%
P9WKI2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	32%	100%
P9WKI3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	32%	100%
P9WKI6	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	43%	93%
P9WKI7	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	43%	93%
Q07152	Drosophila melanogaster	36%	92%
Q0WD32	Yersinia pestis	41%	100%
Q12658	Pneumocystis carinii	36%	93%
Q1C3T0	Yersinia pestis bv. Antiqua (strain Antiqua)	31%	100%
Q1CLY8	Yersinia pestis bv. Antiqua (strain Nepal516)	31%	100%
Q2FJM6	Staphylococcus aureus (strain USA300)	45%	100%
Q2G0Y7	Staphylococcus aureus (strain NCTC 8325 / PS 47)	45%	100%
Q2YVL6	Staphylococcus aureus (strain bovine RF122 / ET3-1)	45%	100%
Q3SWY3	Bos taurus	36%	96%
Q49729	Mycobacterium leprae (strain TN)	43%	93%
Q49UU8	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	44%	100%
Q4L385	Staphylococcus haemolyticus (strain JCSC1435)	44%	100%
Q4QD53	Leishmania major	36%	100%
Q4QEB3	Leishmania major	92%	100%
Q4VRV8	Toxoplasma gondii	39%	89%
Q4WHZ9	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	37%	90%
Q54QQ0	Dictyostelium discoideum	37%	96%
Q59011	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	44%	99%
Q59Q46	Candida albicans (strain SC5314 / ATCC MYA-2876)	37%	94%
Q5HIQ7	Staphylococcus aureus (strain COL)	45%	100%
Q5HRX2	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	44%	100%
Q5KP44	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	36%	90%
Q5PDH8	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	31%	100%
Q5RGV1	Danio rerio	35%	96%
Q5X9A3	Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)	45%	100%
Q66EJ0	Yersinia pseudotuberculosis serotype I (strain IP32953)	31%	100%
Q6GC82	Staphylococcus aureus (strain MSSA476)	45%	100%
Q6GJQ7	Staphylococcus aureus (strain MRSA252)	45%	100%
Q6GMG5	Danio rerio	36%	90%
Q7SFX7	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	37%	92%
Q7UJL3	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	44%	91%
Q84XA3	Vigna unguiculata	33%	98%
Q8CMQ7	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	44%	100%
Q8F4Q4	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)	38%	97%
Q8G3N6	Bifidobacterium longum (strain NCC 2705)	45%	90%
Q8KCW4	Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)	43%	100%
Q8NY70	Staphylococcus aureus (strain MW2)	45%	100%
Q8Z9F9	Salmonella typhi	31%	100%
Q8ZBI2	Yersinia pestis	31%	100%
Q8ZRT5	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	31%	100%
Q9GZH3	Caenorhabditis elegans	33%	92%
Q9HLK8	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	44%	100%
Q9HQU4	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	42%	99%
Q9KGN8	Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	48%	100%
Q9KH33	Rhizobium tropici	43%	99%
Q9L6B7	Pasteurella multocida (strain Pm70)	43%	100%
Q9SA34	Arabidopsis thaliana	33%	98%
Q9UY49	Pyrococcus abyssi (strain GE5 / Orsay)	45%	100%
Q9Z244	Rattus norvegicus	32%	100%
Q9ZL14	Helicobacter pylori (strain J99 / ATCC 700824)	44%	100%
V5BAV1	Trypanosoma cruzi	74%	100%
V5BDG8	Trypanosoma cruzi	38%	100%
W6QIT2	Penicillium roqueforti (strain FM164)	36%	94%