Str_synth domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4H906_LEIBR

TriTrypDb:

LbrM.17.0620 , LBRM2903_170012400

Length:

418

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H906

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H906

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	1
GO:0016491	oxidoreductase activity	2	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	11	15	PF00656	0.292
CLV_C14_Caspase3-7	72	76	PF00656	0.470
CLV_NRD_NRD_1	234	236	PF00675	0.554
CLV_PCSK_KEX2_1	233	235	PF00082	0.520
CLV_PCSK_PC1ET2_1	233	235	PF00082	0.407
CLV_PCSK_SKI1_1	28	32	PF00082	0.428
CLV_PCSK_SKI1_1	377	381	PF00082	0.392
DEG_APCC_DBOX_1	233	241	PF00400	0.559
DEG_APCC_KENBOX_2	274	278	PF00400	0.311
DOC_CYCLIN_yCln2_LP_2	226	232	PF00134	0.412

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ICT3	Leishmania donovani	76%	100%
A0A3Q8IJF2	Leishmania donovani	76%	100%
A4HXD7	Leishmania infantum	76%	100%
E9AR32	Leishmania mexicana (strain MHOM/GT/2001/U1103)	75%	100%
Q4QED1	Leishmania major	75%	100%

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