LeishMANIAdb
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ATP pyrophosphate-lyase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP pyrophosphate-lyase
Gene product:
receptor-type adenylate cyclase b
Species:
Leishmania braziliensis
UniProt:
A4H8V8_LEIBR
TriTrypDb:
LbrM.17.0130 , LBRM2903_350042800
Length:
1405

Annotations

LeishMANIAdb annotations

Carries an ATP pyrophosphate-lyase domain on its cytoplasmic segment. Likely acts as a receptor for some unknown extracellular stimulus. Extremely expanded kinetoplastid protein family.. Expressed in the insect stage (promastigote) but not in the mammalian host stage of the parasite life cycle.. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 57
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 46, no: 26
NetGPI no yes: 0, no: 72
Cellular components
Term Name Level Count
GO:0016020 membrane 2 67
GO:0110165 cellular anatomical entity 1 73

Expansion

Sequence features

A4H8V8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 73
GO:0006163 purine nucleotide metabolic process 5 73
GO:0006164 purine nucleotide biosynthetic process 6 73
GO:0006171 cAMP biosynthetic process 8 73
GO:0006725 cellular aromatic compound metabolic process 3 73
GO:0006753 nucleoside phosphate metabolic process 4 73
GO:0006793 phosphorus metabolic process 3 73
GO:0006796 phosphate-containing compound metabolic process 4 73
GO:0006807 nitrogen compound metabolic process 2 73
GO:0007165 signal transduction 2 73
GO:0008152 metabolic process 1 73
GO:0009058 biosynthetic process 2 73
GO:0009117 nucleotide metabolic process 5 73
GO:0009150 purine ribonucleotide metabolic process 6 73
GO:0009152 purine ribonucleotide biosynthetic process 7 73
GO:0009165 nucleotide biosynthetic process 6 73
GO:0009187 cyclic nucleotide metabolic process 6 73
GO:0009190 cyclic nucleotide biosynthetic process 7 73
GO:0009259 ribonucleotide metabolic process 5 73
GO:0009260 ribonucleotide biosynthetic process 6 73
GO:0009987 cellular process 1 73
GO:0018130 heterocycle biosynthetic process 4 73
GO:0019438 aromatic compound biosynthetic process 4 73
GO:0019637 organophosphate metabolic process 3 73
GO:0019693 ribose phosphate metabolic process 4 73
GO:0034641 cellular nitrogen compound metabolic process 3 73
GO:0034654 nucleobase-containing compound biosynthetic process 4 73
GO:0035556 intracellular signal transduction 3 73
GO:0044237 cellular metabolic process 2 73
GO:0044238 primary metabolic process 2 73
GO:0044249 cellular biosynthetic process 3 73
GO:0044271 cellular nitrogen compound biosynthetic process 4 73
GO:0044281 small molecule metabolic process 2 73
GO:0046058 cAMP metabolic process 7 73
GO:0046390 ribose phosphate biosynthetic process 5 73
GO:0046483 heterocycle metabolic process 3 73
GO:0050789 regulation of biological process 2 73
GO:0050794 regulation of cellular process 3 73
GO:0052652 cyclic purine nucleotide metabolic process 6 73
GO:0055086 nucleobase-containing small molecule metabolic process 3 73
GO:0065007 biological regulation 1 73
GO:0071704 organic substance metabolic process 2 73
GO:0072521 purine-containing compound metabolic process 4 73
GO:0072522 purine-containing compound biosynthetic process 5 73
GO:0090407 organophosphate biosynthetic process 4 73
GO:1901135 carbohydrate derivative metabolic process 3 73
GO:1901137 carbohydrate derivative biosynthetic process 4 73
GO:1901293 nucleoside phosphate biosynthetic process 5 73
GO:1901360 organic cyclic compound metabolic process 3 73
GO:1901362 organic cyclic compound biosynthetic process 4 73
GO:1901564 organonitrogen compound metabolic process 3 73
GO:1901566 organonitrogen compound biosynthetic process 4 73
GO:1901576 organic substance biosynthetic process 3 73
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 62
GO:0016829 lyase activity 2 62

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 247 251 PF00656 0.313
CLV_C14_Caspase3-7 480 484 PF00656 0.318
CLV_C14_Caspase3-7 811 815 PF00656 0.263
CLV_C14_Caspase3-7 922 926 PF00656 0.592
CLV_C14_Caspase3-7 983 987 PF00656 0.507
CLV_MEL_PAP_1 1056 1062 PF00089 0.299
CLV_NRD_NRD_1 1146 1148 PF00675 0.439
CLV_NRD_NRD_1 1314 1316 PF00675 0.524
CLV_NRD_NRD_1 1354 1356 PF00675 0.634
CLV_NRD_NRD_1 1363 1365 PF00675 0.601
CLV_NRD_NRD_1 207 209 PF00675 0.620
CLV_NRD_NRD_1 30 32 PF00675 0.561
CLV_NRD_NRD_1 393 395 PF00675 0.524
CLV_NRD_NRD_1 440 442 PF00675 0.428
CLV_NRD_NRD_1 632 634 PF00675 0.623
CLV_NRD_NRD_1 689 691 PF00675 0.625
CLV_NRD_NRD_1 9 11 PF00675 0.570
CLV_PCSK_FUR_1 205 209 PF00082 0.617
CLV_PCSK_KEX2_1 1146 1148 PF00082 0.439
CLV_PCSK_KEX2_1 1314 1316 PF00082 0.523
CLV_PCSK_KEX2_1 1354 1356 PF00082 0.634
CLV_PCSK_KEX2_1 1363 1365 PF00082 0.601
CLV_PCSK_KEX2_1 207 209 PF00082 0.620
CLV_PCSK_KEX2_1 24 26 PF00082 0.615
CLV_PCSK_KEX2_1 30 32 PF00082 0.550
CLV_PCSK_KEX2_1 393 395 PF00082 0.512
CLV_PCSK_KEX2_1 440 442 PF00082 0.408
CLV_PCSK_KEX2_1 632 634 PF00082 0.561
CLV_PCSK_KEX2_1 689 691 PF00082 0.559
CLV_PCSK_KEX2_1 9 11 PF00082 0.570
CLV_PCSK_PC1ET2_1 24 26 PF00082 0.683
CLV_PCSK_SKI1_1 1239 1243 PF00082 0.444
CLV_PCSK_SKI1_1 129 133 PF00082 0.557
CLV_PCSK_SKI1_1 208 212 PF00082 0.618
CLV_PCSK_SKI1_1 284 288 PF00082 0.555
CLV_PCSK_SKI1_1 305 309 PF00082 0.506
CLV_PCSK_SKI1_1 393 397 PF00082 0.624
CLV_PCSK_SKI1_1 541 545 PF00082 0.449
CLV_PCSK_SKI1_1 632 636 PF00082 0.515
CLV_PCSK_SKI1_1 642 646 PF00082 0.634
CLV_PCSK_SKI1_1 746 750 PF00082 0.536
CLV_PCSK_SKI1_1 802 806 PF00082 0.551
CLV_PCSK_SKI1_1 808 812 PF00082 0.533
CLV_Separin_Metazoa 605 609 PF03568 0.317
DEG_APCC_DBOX_1 1124 1132 PF00400 0.414
DEG_APCC_DBOX_1 1314 1322 PF00400 0.548
DEG_APCC_DBOX_1 189 197 PF00400 0.257
DEG_SPOP_SBC_1 290 294 PF00917 0.447
DEG_SPOP_SBC_1 735 739 PF00917 0.306
DOC_CDC14_PxL_1 131 139 PF14671 0.444
DOC_CKS1_1 230 235 PF01111 0.228
DOC_CKS1_1 782 787 PF01111 0.386
DOC_CKS1_1 874 879 PF01111 0.413
DOC_CYCLIN_RxL_1 507 516 PF00134 0.289
DOC_CYCLIN_yCln2_LP_2 230 236 PF00134 0.337
DOC_CYCLIN_yCln2_LP_2 508 514 PF00134 0.398
DOC_CYCLIN_yCln2_LP_2 871 877 PF00134 0.419
DOC_MAPK_gen_1 1311 1320 PF00069 0.642
DOC_MAPK_gen_1 205 214 PF00069 0.323
DOC_MAPK_MEF2A_6 510 519 PF00069 0.441
DOC_MAPK_MEF2A_6 714 722 PF00069 0.290
DOC_MAPK_RevD_3 1133 1147 PF00069 0.629
DOC_PP1_RVXF_1 1378 1385 PF00149 0.544
DOC_PP1_RVXF_1 303 309 PF00149 0.435
DOC_PP1_RVXF_1 508 515 PF00149 0.290
DOC_PP1_RVXF_1 688 695 PF00149 0.246
DOC_PP1_RVXF_1 744 751 PF00149 0.323
DOC_PP2B_LxvP_1 236 239 PF13499 0.342
DOC_PP2B_LxvP_1 871 874 PF13499 0.494
DOC_PP4_FxxP_1 1348 1351 PF00568 0.579
DOC_PP4_FxxP_1 50 53 PF00568 0.414
DOC_USP7_MATH_1 1245 1249 PF00917 0.703
DOC_USP7_MATH_1 1290 1294 PF00917 0.819
DOC_USP7_MATH_1 1365 1369 PF00917 0.795
DOC_USP7_MATH_1 290 294 PF00917 0.445
DOC_USP7_MATH_1 477 481 PF00917 0.441
DOC_USP7_MATH_1 712 716 PF00917 0.397
DOC_USP7_MATH_1 735 739 PF00917 0.420
DOC_USP7_MATH_1 778 782 PF00917 0.432
DOC_USP7_MATH_1 991 995 PF00917 0.576
DOC_WW_Pin1_4 152 157 PF00397 0.392
DOC_WW_Pin1_4 2 7 PF00397 0.346
DOC_WW_Pin1_4 229 234 PF00397 0.395
DOC_WW_Pin1_4 29 34 PF00397 0.452
DOC_WW_Pin1_4 318 323 PF00397 0.424
DOC_WW_Pin1_4 736 741 PF00397 0.377
DOC_WW_Pin1_4 764 769 PF00397 0.440
DOC_WW_Pin1_4 781 786 PF00397 0.380
DOC_WW_Pin1_4 873 878 PF00397 0.375
DOC_WW_Pin1_4 888 893 PF00397 0.454
LIG_14-3-3_CanoR_1 1043 1049 PF00244 0.634
LIG_14-3-3_CanoR_1 1225 1232 PF00244 0.683
LIG_14-3-3_CanoR_1 1243 1248 PF00244 0.662
LIG_14-3-3_CanoR_1 205 214 PF00244 0.363
LIG_14-3-3_CanoR_1 25 30 PF00244 0.454
LIG_14-3-3_CanoR_1 284 290 PF00244 0.427
LIG_14-3-3_CanoR_1 291 298 PF00244 0.413
LIG_14-3-3_CanoR_1 559 566 PF00244 0.287
LIG_14-3-3_CanoR_1 632 641 PF00244 0.416
LIG_14-3-3_CanoR_1 662 668 PF00244 0.371
LIG_14-3-3_CanoR_1 746 751 PF00244 0.449
LIG_14-3-3_CanoR_1 789 798 PF00244 0.319
LIG_14-3-3_CanoR_1 802 808 PF00244 0.334
LIG_14-3-3_CanoR_1 884 892 PF00244 0.484
LIG_Actin_WH2_2 529 546 PF00022 0.419
LIG_Actin_WH2_2 617 634 PF00022 0.227
LIG_APCC_ABBA_1 141 146 PF00400 0.444
LIG_APCC_ABBA_1 308 313 PF00400 0.303
LIG_APCC_ABBA_1 719 724 PF00400 0.311
LIG_BIR_III_2 1141 1145 PF00653 0.614
LIG_BIR_III_2 765 769 PF00653 0.266
LIG_BIR_III_2 927 931 PF00653 0.671
LIG_BRCT_BRCA1_1 1309 1313 PF00533 0.741
LIG_eIF4E_1 29 35 PF01652 0.501
LIG_eIF4E_1 598 604 PF01652 0.263
LIG_FHA_1 1005 1011 PF00498 0.570
LIG_FHA_1 1014 1020 PF00498 0.506
LIG_FHA_1 1039 1045 PF00498 0.517
LIG_FHA_1 1089 1095 PF00498 0.512
LIG_FHA_1 126 132 PF00498 0.414
LIG_FHA_1 339 345 PF00498 0.372
LIG_FHA_1 356 362 PF00498 0.464
LIG_FHA_1 406 412 PF00498 0.350
LIG_FHA_1 44 50 PF00498 0.441
LIG_FHA_1 522 528 PF00498 0.329
LIG_FHA_1 552 558 PF00498 0.401
LIG_FHA_1 572 578 PF00498 0.339
LIG_FHA_1 655 661 PF00498 0.353
LIG_FHA_1 678 684 PF00498 0.400
LIG_FHA_1 728 734 PF00498 0.378
LIG_FHA_1 791 797 PF00498 0.298
LIG_FHA_1 874 880 PF00498 0.345
LIG_FHA_2 1151 1157 PF00498 0.741
LIG_FHA_2 1161 1167 PF00498 0.724
LIG_FHA_2 213 219 PF00498 0.359
LIG_FHA_2 254 260 PF00498 0.430
LIG_FHA_2 319 325 PF00498 0.433
LIG_FHA_2 417 423 PF00498 0.397
LIG_FHA_2 487 493 PF00498 0.334
LIG_FHA_2 697 703 PF00498 0.341
LIG_FHA_2 809 815 PF00498 0.301
LIG_FHA_2 889 895 PF00498 0.415
LIG_FHA_2 940 946 PF00498 0.507
LIG_FHA_2 981 987 PF00498 0.511
LIG_GBD_Chelix_1 1001 1009 PF00786 0.417
LIG_GBD_Chelix_1 279 287 PF00786 0.535
LIG_GBD_Chelix_1 578 586 PF00786 0.429
LIG_LIR_Apic_2 1034 1040 PF02991 0.491
LIG_LIR_Apic_2 452 456 PF02991 0.368
LIG_LIR_Apic_2 589 594 PF02991 0.364
LIG_LIR_Apic_2 666 672 PF02991 0.443
LIG_LIR_Gen_1 1046 1056 PF02991 0.562
LIG_LIR_Gen_1 1068 1078 PF02991 0.603
LIG_LIR_Gen_1 209 219 PF02991 0.451
LIG_LIR_Gen_1 221 231 PF02991 0.338
LIG_LIR_Gen_1 256 266 PF02991 0.343
LIG_LIR_Gen_1 281 290 PF02991 0.426
LIG_LIR_Gen_1 484 495 PF02991 0.439
LIG_LIR_Gen_1 504 512 PF02991 0.311
LIG_LIR_Gen_1 749 755 PF02991 0.362
LIG_LIR_Gen_1 938 949 PF02991 0.508
LIG_LIR_Nem_3 1013 1017 PF02991 0.526
LIG_LIR_Nem_3 1020 1026 PF02991 0.509
LIG_LIR_Nem_3 1046 1052 PF02991 0.507
LIG_LIR_Nem_3 1068 1074 PF02991 0.525
LIG_LIR_Nem_3 1075 1081 PF02991 0.486
LIG_LIR_Nem_3 1104 1110 PF02991 0.519
LIG_LIR_Nem_3 1194 1200 PF02991 0.647
LIG_LIR_Nem_3 133 137 PF02991 0.382
LIG_LIR_Nem_3 209 214 PF02991 0.451
LIG_LIR_Nem_3 221 227 PF02991 0.352
LIG_LIR_Nem_3 264 268 PF02991 0.257
LIG_LIR_Nem_3 281 285 PF02991 0.441
LIG_LIR_Nem_3 430 435 PF02991 0.444
LIG_LIR_Nem_3 484 490 PF02991 0.377
LIG_LIR_Nem_3 492 498 PF02991 0.306
LIG_LIR_Nem_3 504 508 PF02991 0.277
LIG_LIR_Nem_3 749 753 PF02991 0.354
LIG_LIR_Nem_3 86 92 PF02991 0.243
LIG_LIR_Nem_3 938 944 PF02991 0.508
LIG_LIR_Nem_3 948 954 PF02991 0.609
LIG_LYPXL_yS_3 134 137 PF13949 0.310
LIG_LYPXL_yS_3 265 268 PF13949 0.222
LIG_MYND_3 614 618 PF01753 0.366
LIG_NRBOX 148 154 PF00104 0.343
LIG_PCNA_yPIPBox_3 533 544 PF02747 0.207
LIG_PCNA_yPIPBox_3 895 903 PF02747 0.262
LIG_PTB_Apo_2 497 504 PF02174 0.221
LIG_PTB_Apo_2 606 613 PF02174 0.317
LIG_PTB_Apo_2 69 76 PF02174 0.364
LIG_PTB_Apo_2 95 102 PF02174 0.247
LIG_PTB_Phospho_1 497 503 PF10480 0.222
LIG_PTB_Phospho_1 606 612 PF10480 0.320
LIG_PTB_Phospho_1 69 75 PF10480 0.373
LIG_PTB_Phospho_1 95 101 PF10480 0.246
LIG_SH2_CRK 242 246 PF00017 0.506
LIG_SH2_CRK 453 457 PF00017 0.366
LIG_SH2_CRK 505 509 PF00017 0.251
LIG_SH2_CRK 669 673 PF00017 0.471
LIG_SH2_CRK 729 733 PF00017 0.441
LIG_SH2_GRB2like 625 628 PF00017 0.388
LIG_SH2_GRB2like 817 820 PF00017 0.424
LIG_SH2_NCK_1 101 105 PF00017 0.448
LIG_SH2_NCK_1 1071 1075 PF00017 0.596
LIG_SH2_NCK_1 669 673 PF00017 0.307
LIG_SH2_PTP2 1037 1040 PF00017 0.546
LIG_SH2_PTP2 610 613 PF00017 0.449
LIG_SH2_SRC 1037 1040 PF00017 0.557
LIG_SH2_SRC 1071 1074 PF00017 0.596
LIG_SH2_SRC 224 227 PF00017 0.395
LIG_SH2_SRC 442 445 PF00017 0.412
LIG_SH2_SRC 84 87 PF00017 0.218
LIG_SH2_STAP1 1049 1053 PF00017 0.563
LIG_SH2_STAP1 224 228 PF00017 0.266
LIG_SH2_STAP1 312 316 PF00017 0.443
LIG_SH2_STAP1 573 577 PF00017 0.360
LIG_SH2_STAP1 625 629 PF00017 0.220
LIG_SH2_STAP1 729 733 PF00017 0.266
LIG_SH2_STAP1 84 88 PF00017 0.279
LIG_SH2_STAT3 354 357 PF00017 0.266
LIG_SH2_STAT3 469 472 PF00017 0.433
LIG_SH2_STAT3 850 853 PF00017 0.340
LIG_SH2_STAT5 101 104 PF00017 0.436
LIG_SH2_STAT5 1037 1040 PF00017 0.488
LIG_SH2_STAT5 1232 1235 PF00017 0.653
LIG_SH2_STAT5 183 186 PF00017 0.347
LIG_SH2_STAT5 213 216 PF00017 0.320
LIG_SH2_STAT5 296 299 PF00017 0.331
LIG_SH2_STAT5 435 438 PF00017 0.325
LIG_SH2_STAT5 442 445 PF00017 0.304
LIG_SH2_STAT5 448 451 PF00017 0.321
LIG_SH2_STAT5 469 472 PF00017 0.395
LIG_SH2_STAT5 497 500 PF00017 0.334
LIG_SH2_STAT5 505 508 PF00017 0.331
LIG_SH2_STAT5 542 545 PF00017 0.361
LIG_SH2_STAT5 573 576 PF00017 0.439
LIG_SH2_STAT5 591 594 PF00017 0.474
LIG_SH2_STAT5 610 613 PF00017 0.370
LIG_SH2_STAT5 69 72 PF00017 0.409
LIG_SH2_STAT5 729 732 PF00017 0.331
LIG_SH2_STAT5 817 820 PF00017 0.340
LIG_SH2_STAT5 918 921 PF00017 0.543
LIG_SH3_1 453 459 PF00018 0.255
LIG_SH3_3 1215 1221 PF00018 0.636
LIG_SH3_3 137 143 PF00018 0.335
LIG_SH3_3 1373 1379 PF00018 0.598
LIG_SH3_3 1382 1388 PF00018 0.557
LIG_SH3_3 453 459 PF00018 0.255
LIG_SH3_3 590 596 PF00018 0.380
LIG_SH3_3 672 678 PF00018 0.374
LIG_SH3_3 863 869 PF00018 0.388
LIG_SH3_3 871 877 PF00018 0.374
LIG_Sin3_3 37 44 PF02671 0.485
LIG_SUMO_SIM_anti_2 122 128 PF11976 0.442
LIG_SUMO_SIM_anti_2 1370 1377 PF11976 0.628
LIG_SUMO_SIM_anti_2 160 167 PF11976 0.372
LIG_SUMO_SIM_anti_2 192 198 PF11976 0.276
LIG_SUMO_SIM_anti_2 225 232 PF11976 0.294
LIG_SUMO_SIM_anti_2 715 721 PF11976 0.344
LIG_SUMO_SIM_anti_2 934 943 PF11976 0.510
LIG_SUMO_SIM_par_1 1015 1020 PF11976 0.414
LIG_SUMO_SIM_par_1 122 128 PF11976 0.411
LIG_SUMO_SIM_par_1 225 232 PF11976 0.294
LIG_SUMO_SIM_par_1 45 51 PF11976 0.434
LIG_SUMO_SIM_par_1 546 554 PF11976 0.387
LIG_SUMO_SIM_par_1 673 680 PF11976 0.292
LIG_SUMO_SIM_par_1 694 699 PF11976 0.396
LIG_SUMO_SIM_par_1 717 724 PF11976 0.399
LIG_SUMO_SIM_par_1 854 859 PF11976 0.337
LIG_SUMO_SIM_par_1 903 909 PF11976 0.449
LIG_SxIP_EBH_1 337 348 PF03271 0.293
LIG_TRAF2_1 1045 1048 PF00917 0.629
LIG_TRAF2_1 1111 1114 PF00917 0.537
LIG_TRAF2_1 1356 1359 PF00917 0.835
LIG_TRAF2_1 421 424 PF00917 0.443
LIG_TRAF2_1 489 492 PF00917 0.225
LIG_TYR_ITIM 1069 1074 PF00017 0.482
LIG_TYR_ITIM 623 628 PF00017 0.438
LIG_TYR_ITIM 727 732 PF00017 0.374
LIG_UBA3_1 193 198 PF00899 0.586
LIG_WRC_WIRS_1 417 422 PF05994 0.221
LIG_WRC_WIRS_1 747 752 PF05994 0.576
LIG_WW_3 1220 1224 PF00397 0.673
LIG_WW_3 1297 1301 PF00397 0.842
MOD_CDK_SPxxK_3 2 9 PF00069 0.346
MOD_CDK_SPxxK_3 888 895 PF00069 0.435
MOD_CK1_1 1178 1184 PF00069 0.514
MOD_CK1_1 1293 1299 PF00069 0.829
MOD_CK1_1 1335 1341 PF00069 0.658
MOD_CK1_1 329 335 PF00069 0.664
MOD_CK1_1 385 391 PF00069 0.649
MOD_CK1_1 504 510 PF00069 0.378
MOD_CK1_1 551 557 PF00069 0.341
MOD_CK1_1 636 642 PF00069 0.389
MOD_CK1_1 654 660 PF00069 0.385
MOD_CK1_1 663 669 PF00069 0.404
MOD_CK1_1 679 685 PF00069 0.498
MOD_CK1_1 757 763 PF00069 0.549
MOD_CK1_1 781 787 PF00069 0.436
MOD_CK1_1 888 894 PF00069 0.475
MOD_CK1_1 994 1000 PF00069 0.506
MOD_CK2_1 1042 1048 PF00069 0.529
MOD_CK2_1 1108 1114 PF00069 0.367
MOD_CK2_1 1150 1156 PF00069 0.665
MOD_CK2_1 1160 1166 PF00069 0.612
MOD_CK2_1 1326 1332 PF00069 0.733
MOD_CK2_1 416 422 PF00069 0.407
MOD_CK2_1 486 492 PF00069 0.334
MOD_CK2_1 80 86 PF00069 0.333
MOD_CK2_1 803 809 PF00069 0.447
MOD_CK2_1 888 894 PF00069 0.551
MOD_CK2_1 939 945 PF00069 0.356
MOD_Cter_Amidation 1144 1147 PF01082 0.535
MOD_Cter_Amidation 205 208 PF01082 0.220
MOD_GlcNHglycan 1169 1172 PF01048 0.593
MOD_GlcNHglycan 1182 1185 PF01048 0.348
MOD_GlcNHglycan 1292 1295 PF01048 0.804
MOD_GlcNHglycan 1302 1307 PF01048 0.728
MOD_GlcNHglycan 1334 1337 PF01048 0.706
MOD_GlcNHglycan 1365 1368 PF01048 0.774
MOD_GlcNHglycan 1394 1397 PF01048 0.729
MOD_GlcNHglycan 160 163 PF01048 0.509
MOD_GlcNHglycan 172 175 PF01048 0.375
MOD_GlcNHglycan 242 245 PF01048 0.542
MOD_GlcNHglycan 250 253 PF01048 0.465
MOD_GlcNHglycan 293 296 PF01048 0.500
MOD_GlcNHglycan 329 332 PF01048 0.667
MOD_GlcNHglycan 387 390 PF01048 0.664
MOD_GlcNHglycan 483 486 PF01048 0.509
MOD_GlcNHglycan 491 495 PF01048 0.457
MOD_GlcNHglycan 536 539 PF01048 0.402
MOD_GlcNHglycan 638 641 PF01048 0.424
MOD_GlcNHglycan 662 665 PF01048 0.508
MOD_GlcNHglycan 684 687 PF01048 0.446
MOD_GlcNHglycan 713 717 PF01048 0.348
MOD_GlcNHglycan 761 764 PF01048 0.470
MOD_GlcNHglycan 840 843 PF01048 0.447
MOD_GlcNHglycan 887 890 PF01048 0.434
MOD_GlcNHglycan 993 996 PF01048 0.447
MOD_GSK3_1 1038 1045 PF00069 0.510
MOD_GSK3_1 1160 1167 PF00069 0.524
MOD_GSK3_1 1174 1181 PF00069 0.593
MOD_GSK3_1 1221 1228 PF00069 0.647
MOD_GSK3_1 1298 1305 PF00069 0.797
MOD_GSK3_1 1326 1333 PF00069 0.736
MOD_GSK3_1 1346 1353 PF00069 0.778
MOD_GSK3_1 1363 1370 PF00069 0.458
MOD_GSK3_1 240 247 PF00069 0.514
MOD_GSK3_1 25 32 PF00069 0.514
MOD_GSK3_1 285 292 PF00069 0.483
MOD_GSK3_1 326 333 PF00069 0.643
MOD_GSK3_1 334 341 PF00069 0.591
MOD_GSK3_1 477 484 PF00069 0.549
MOD_GSK3_1 486 493 PF00069 0.357
MOD_GSK3_1 513 520 PF00069 0.410
MOD_GSK3_1 632 639 PF00069 0.394
MOD_GSK3_1 727 734 PF00069 0.490
MOD_GSK3_1 735 742 PF00069 0.484
MOD_GSK3_1 754 761 PF00069 0.417
MOD_GSK3_1 834 841 PF00069 0.422
MOD_GSK3_1 869 876 PF00069 0.489
MOD_GSK3_1 884 891 PF00069 0.482
MOD_GSK3_1 935 942 PF00069 0.374
MOD_GSK3_1 980 987 PF00069 0.365
MOD_N-GLC_1 339 344 PF02516 0.433
MOD_N-GLC_1 571 576 PF02516 0.478
MOD_N-GLC_2 500 502 PF02516 0.240
MOD_NEK2_1 1175 1180 PF00069 0.549
MOD_NEK2_1 1191 1196 PF00069 0.253
MOD_NEK2_1 1307 1312 PF00069 0.569
MOD_NEK2_1 169 174 PF00069 0.471
MOD_NEK2_1 212 217 PF00069 0.491
MOD_NEK2_1 248 253 PF00069 0.449
MOD_NEK2_1 261 266 PF00069 0.363
MOD_NEK2_1 327 332 PF00069 0.426
MOD_NEK2_1 355 360 PF00069 0.550
MOD_NEK2_1 405 410 PF00069 0.398
MOD_NEK2_1 660 665 PF00069 0.380
MOD_NEK2_1 696 701 PF00069 0.459
MOD_NEK2_1 727 732 PF00069 0.349
MOD_NEK2_1 800 805 PF00069 0.421
MOD_NEK2_2 296 301 PF00069 0.307
MOD_PIKK_1 1245 1251 PF00454 0.657
MOD_PIKK_1 334 340 PF00454 0.472
MOD_PIKK_1 778 784 PF00454 0.539
MOD_PK_1 633 639 PF00069 0.475
MOD_PKA_1 1330 1336 PF00069 0.462
MOD_PKA_1 1354 1360 PF00069 0.576
MOD_PKA_1 1363 1369 PF00069 0.487
MOD_PKA_1 632 638 PF00069 0.472
MOD_PKA_2 1042 1048 PF00069 0.533
MOD_PKA_2 1290 1296 PF00069 0.826
MOD_PKA_2 1307 1313 PF00069 0.631
MOD_PKA_2 1354 1360 PF00069 0.587
MOD_PKA_2 1363 1369 PF00069 0.489
MOD_PKA_2 206 212 PF00069 0.558
MOD_PKA_2 290 296 PF00069 0.493
MOD_PKA_2 558 564 PF00069 0.469
MOD_PKA_2 632 638 PF00069 0.426
MOD_PKB_1 1223 1231 PF00069 0.706
MOD_PKB_1 882 890 PF00069 0.388
MOD_Plk_1 253 259 PF00069 0.484
MOD_Plk_1 339 345 PF00069 0.498
MOD_Plk_1 361 367 PF00069 0.425
MOD_Plk_1 427 433 PF00069 0.392
MOD_Plk_1 651 657 PF00069 0.397
MOD_Plk_1 712 718 PF00069 0.472
MOD_Plk_1 808 814 PF00069 0.422
MOD_Plk_2-3 980 986 PF00069 0.355
MOD_Plk_4 133 139 PF00069 0.483
MOD_Plk_4 361 367 PF00069 0.530
MOD_Plk_4 411 417 PF00069 0.531
MOD_Plk_4 513 519 PF00069 0.435
MOD_Plk_4 670 676 PF00069 0.300
MOD_Plk_4 783 789 PF00069 0.417
MOD_Plk_4 851 857 PF00069 0.414
MOD_Plk_4 875 881 PF00069 0.446
MOD_Plk_4 935 941 PF00069 0.355
MOD_Plk_4 984 990 PF00069 0.369
MOD_ProDKin_1 152 158 PF00069 0.470
MOD_ProDKin_1 2 8 PF00069 0.346
MOD_ProDKin_1 229 235 PF00069 0.475
MOD_ProDKin_1 29 35 PF00069 0.451
MOD_ProDKin_1 318 324 PF00069 0.523
MOD_ProDKin_1 736 742 PF00069 0.453
MOD_ProDKin_1 764 770 PF00069 0.545
MOD_ProDKin_1 781 787 PF00069 0.456
MOD_ProDKin_1 873 879 PF00069 0.447
MOD_ProDKin_1 888 894 PF00069 0.556
MOD_SUMO_rev_2 364 373 PF00179 0.588
TRG_DiLeu_BaEn_1 66 71 PF01217 0.509
TRG_DiLeu_BaEn_1 935 940 PF01217 0.483
TRG_DiLeu_BaEn_2 179 185 PF01217 0.571
TRG_DiLeu_BaEn_2 617 623 PF01217 0.359
TRG_DiLeu_BaLyEn_6 30 35 PF01217 0.467
TRG_DiLeu_LyEn_5 1208 1213 PF01217 0.559
TRG_ENDOCYTIC_2 1023 1026 PF00928 0.363
TRG_ENDOCYTIC_2 1049 1052 PF00928 0.343
TRG_ENDOCYTIC_2 1071 1074 PF00928 0.480
TRG_ENDOCYTIC_2 134 137 PF00928 0.523
TRG_ENDOCYTIC_2 224 227 PF00928 0.517
TRG_ENDOCYTIC_2 265 268 PF00928 0.519
TRG_ENDOCYTIC_2 311 314 PF00928 0.498
TRG_ENDOCYTIC_2 505 508 PF00928 0.275
TRG_ENDOCYTIC_2 610 613 PF00928 0.559
TRG_ENDOCYTIC_2 625 628 PF00928 0.475
TRG_ENDOCYTIC_2 729 732 PF00928 0.380
TRG_ENDOCYTIC_2 918 921 PF00928 0.476
TRG_ER_diArg_1 1056 1059 PF00400 0.356
TRG_ER_diArg_1 1222 1225 PF00400 0.642
TRG_ER_diArg_1 1251 1254 PF00400 0.599
TRG_ER_diArg_1 1313 1315 PF00400 0.505
TRG_ER_diArg_1 204 207 PF00400 0.490
TRG_ER_diArg_1 29 31 PF00400 0.454
TRG_ER_diArg_1 392 394 PF00400 0.399
TRG_ER_diArg_1 440 442 PF00400 0.212
TRG_ER_diArg_1 631 633 PF00400 0.241
TRG_ER_diArg_1 688 690 PF00400 0.551
TRG_ER_diArg_1 8 10 PF00400 0.446
TRG_ER_diArg_1 881 884 PF00400 0.508
TRG_Pf-PMV_PEXEL_1 967 971 PF00026 0.427

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P457 Leptomonas seymouri 26% 100%
A0A1X0P171 Trypanosomatidae 34% 100%
A0A3Q8IJB0 Leishmania donovani 70% 100%
A0A3R7R8G4 Trypanosoma rangeli 33% 100%
A0A3S5H6Z8 Leishmania donovani 70% 100%
A0A3S7WU91 Leishmania donovani 59% 99%
A0A3S7WU94 Leishmania donovani 53% 100%
A0A3S7WU95 Leishmania donovani 68% 100%
A0A3S7XB85 Leishmania donovani 28% 100%
A4H8U6 Leishmania braziliensis 64% 100%
A4H8V5 Leishmania braziliensis 70% 100%
A4H8V7 Leishmania braziliensis 91% 100%
A4HPI4 Leishmania braziliensis 27% 100%
A4HX84 Leishmania infantum 53% 100%
A4HX85 Leishmania infantum 70% 100%
A4HX87 Leishmania infantum 59% 100%
A4IDA6 Leishmania infantum 28% 100%
C9ZM79 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZM80 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZM81 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZM82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZM83 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZM86 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZN26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN41 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 100%
C9ZN43 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN44 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN45 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 100%
C9ZN46 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZNA5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZNA6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZNH3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZNT1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZPZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZQ51 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZQ89 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZQ90 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ92 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZTS4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZTS5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZTS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZUE6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWQ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZWY7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZZQ4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A0U3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A0W7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
D0A0X5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
D0A1S1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5U0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
D0A5U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
D0A7A0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A9R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0AAV3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
E9AQY0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 59% 100%
E9AQY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 55% 100%
E9AQY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 68% 100%
E9AQY4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 70% 100%
E9ARD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 54% 100%
E9AT96 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 100%
Q25263 Leishmania donovani 71% 100%
Q26721 Trypanosoma brucei brucei 35% 100%
Q27675 Leishmania donovani 53% 100%
Q4Q1A1 Leishmania major 28% 100%
Q4QEH9 Leishmania major 70% 100%
Q4QEI0 Leishmania major 70% 100%
Q4QEI1 Leishmania major 71% 100%
Q4QEI2 Leishmania major 58% 100%
Q4QEI3 Leishmania major 52% 100%
Q99279 Trypanosoma brucei brucei 30% 100%
Q99280 Trypanosoma brucei brucei 33% 100%
V5AYH7 Trypanosoma cruzi 36% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS