LeishMANIAdb
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ATP pyrophosphate-lyase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP pyrophosphate-lyase
Gene product:
receptor-type adenylate cyclase b
Species:
Leishmania braziliensis
UniProt:
A4H8V7_LEIBR
TriTrypDb:
LbrM.17.0120 , LBRM2903_350042800
Length:
1144

Annotations

LeishMANIAdb annotations

Carries an ATP pyrophosphate-lyase domain on its cytoplasmic segment. Likely acts as a receptor for some unknown extracellular stimulus. Extremely expanded kinetoplastid protein family.. Expressed in the insect stage (promastigote) but not in the mammalian host stage of the parasite life cycle.. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 60
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 47, no: 29
NetGPI no yes: 0, no: 76
Cellular components
Term Name Level Count
GO:0016020 membrane 2 71
GO:0110165 cellular anatomical entity 1 77

Expansion

Sequence features

A4H8V7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H8V7

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 75
GO:0006163 purine nucleotide metabolic process 5 75
GO:0006164 purine nucleotide biosynthetic process 6 75
GO:0006171 cAMP biosynthetic process 8 75
GO:0006725 cellular aromatic compound metabolic process 3 75
GO:0006753 nucleoside phosphate metabolic process 4 75
GO:0006793 phosphorus metabolic process 3 75
GO:0006796 phosphate-containing compound metabolic process 4 75
GO:0006807 nitrogen compound metabolic process 2 75
GO:0007165 signal transduction 2 75
GO:0008152 metabolic process 1 75
GO:0009058 biosynthetic process 2 75
GO:0009117 nucleotide metabolic process 5 75
GO:0009150 purine ribonucleotide metabolic process 6 75
GO:0009152 purine ribonucleotide biosynthetic process 7 75
GO:0009165 nucleotide biosynthetic process 6 75
GO:0009187 cyclic nucleotide metabolic process 6 75
GO:0009190 cyclic nucleotide biosynthetic process 7 75
GO:0009259 ribonucleotide metabolic process 5 75
GO:0009260 ribonucleotide biosynthetic process 6 75
GO:0009987 cellular process 1 75
GO:0018130 heterocycle biosynthetic process 4 75
GO:0019438 aromatic compound biosynthetic process 4 75
GO:0019637 organophosphate metabolic process 3 75
GO:0019693 ribose phosphate metabolic process 4 75
GO:0034641 cellular nitrogen compound metabolic process 3 75
GO:0034654 nucleobase-containing compound biosynthetic process 4 75
GO:0035556 intracellular signal transduction 3 75
GO:0044237 cellular metabolic process 2 75
GO:0044238 primary metabolic process 2 75
GO:0044249 cellular biosynthetic process 3 75
GO:0044271 cellular nitrogen compound biosynthetic process 4 75
GO:0044281 small molecule metabolic process 2 75
GO:0046058 cAMP metabolic process 7 75
GO:0046390 ribose phosphate biosynthetic process 5 75
GO:0046483 heterocycle metabolic process 3 75
GO:0050789 regulation of biological process 2 75
GO:0050794 regulation of cellular process 3 75
GO:0052652 cyclic purine nucleotide metabolic process 6 75
GO:0055086 nucleobase-containing small molecule metabolic process 3 75
GO:0065007 biological regulation 1 75
GO:0071704 organic substance metabolic process 2 75
GO:0072521 purine-containing compound metabolic process 4 75
GO:0072522 purine-containing compound biosynthetic process 5 75
GO:0090407 organophosphate biosynthetic process 4 75
GO:1901135 carbohydrate derivative metabolic process 3 75
GO:1901137 carbohydrate derivative biosynthetic process 4 75
GO:1901293 nucleoside phosphate biosynthetic process 5 75
GO:1901360 organic cyclic compound metabolic process 3 75
GO:1901362 organic cyclic compound biosynthetic process 4 75
GO:1901564 organonitrogen compound metabolic process 3 75
GO:1901566 organonitrogen compound biosynthetic process 4 75
GO:1901576 organic substance biosynthetic process 3 75
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 64
GO:0016829 lyase activity 2 64
GO:0004016 adenylate cyclase activity 3 1
GO:0009975 cyclase activity 2 1
GO:0016849 phosphorus-oxygen lyase activity 3 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 218 222 PF00656 0.332
CLV_C14_Caspase3-7 661 665 PF00656 0.664
CLV_C14_Caspase3-7 722 726 PF00656 0.505
CLV_MEL_PAP_1 795 801 PF00089 0.298
CLV_NRD_NRD_1 1053 1055 PF00675 0.613
CLV_NRD_NRD_1 1093 1095 PF00675 0.499
CLV_NRD_NRD_1 1102 1104 PF00675 0.647
CLV_NRD_NRD_1 131 133 PF00675 0.705
CLV_NRD_NRD_1 371 373 PF00675 0.675
CLV_NRD_NRD_1 428 430 PF00675 0.673
CLV_NRD_NRD_1 885 887 PF00675 0.422
CLV_PCSK_KEX2_1 1053 1055 PF00082 0.605
CLV_PCSK_KEX2_1 1093 1095 PF00082 0.499
CLV_PCSK_KEX2_1 1102 1104 PF00082 0.657
CLV_PCSK_KEX2_1 131 133 PF00082 0.506
CLV_PCSK_KEX2_1 371 373 PF00082 0.627
CLV_PCSK_KEX2_1 428 430 PF00082 0.607
CLV_PCSK_KEX2_1 885 887 PF00082 0.422
CLV_PCSK_SKI1_1 131 135 PF00082 0.619
CLV_PCSK_SKI1_1 22 26 PF00082 0.561
CLV_PCSK_SKI1_1 287 291 PF00082 0.501
CLV_PCSK_SKI1_1 371 375 PF00082 0.571
CLV_PCSK_SKI1_1 381 385 PF00082 0.620
CLV_PCSK_SKI1_1 43 47 PF00082 0.550
CLV_PCSK_SKI1_1 485 489 PF00082 0.521
CLV_PCSK_SKI1_1 978 982 PF00082 0.455
CLV_Separin_Metazoa 344 348 PF03568 0.337
DEG_APCC_DBOX_1 1053 1061 PF00400 0.632
DEG_APCC_DBOX_1 863 871 PF00400 0.413
DEG_Nend_UBRbox_3 1 2 PF02207 0.345
DEG_SPOP_SBC_1 263 267 PF00917 0.426
DEG_SPOP_SBC_1 28 32 PF00917 0.500
DEG_SPOP_SBC_1 474 478 PF00917 0.331
DOC_CKS1_1 613 618 PF01111 0.405
DOC_CYCLIN_RxL_1 244 255 PF00134 0.341
DOC_CYCLIN_yCln2_LP_2 247 253 PF00134 0.454
DOC_CYCLIN_yCln2_LP_2 610 616 PF00134 0.405
DOC_MAPK_gen_1 1050 1059 PF00069 0.726
DOC_MAPK_MEF2A_6 249 258 PF00069 0.459
DOC_MAPK_MEF2A_6 453 461 PF00069 0.310
DOC_MAPK_RevD_3 872 886 PF00069 0.618
DOC_PP1_RVXF_1 1117 1124 PF00149 0.586
DOC_PP1_RVXF_1 247 254 PF00149 0.335
DOC_PP1_RVXF_1 278 285 PF00149 0.413
DOC_PP1_RVXF_1 41 47 PF00149 0.468
DOC_PP1_RVXF_1 427 434 PF00149 0.264
DOC_PP1_RVXF_1 483 490 PF00149 0.312
DOC_PP2B_LxvP_1 610 613 PF13499 0.483
DOC_PP4_FxxP_1 1087 1090 PF00568 0.630
DOC_USP7_MATH_1 1029 1033 PF00917 0.827
DOC_USP7_MATH_1 1104 1108 PF00917 0.832
DOC_USP7_MATH_1 215 219 PF00917 0.476
DOC_USP7_MATH_1 263 267 PF00917 0.306
DOC_USP7_MATH_1 28 32 PF00917 0.498
DOC_USP7_MATH_1 451 455 PF00917 0.437
DOC_USP7_MATH_1 474 478 PF00917 0.445
DOC_USP7_MATH_1 730 734 PF00917 0.568
DOC_USP7_MATH_1 984 988 PF00917 0.714
DOC_WW_Pin1_4 475 480 PF00397 0.407
DOC_WW_Pin1_4 520 525 PF00397 0.365
DOC_WW_Pin1_4 540 545 PF00397 0.259
DOC_WW_Pin1_4 56 61 PF00397 0.461
DOC_WW_Pin1_4 612 617 PF00397 0.367
DOC_WW_Pin1_4 627 632 PF00397 0.531
DOC_WW_Pin1_4 820 825 PF00397 0.548
LIG_14-3-3_CanoR_1 162 170 PF00244 0.403
LIG_14-3-3_CanoR_1 22 28 PF00244 0.446
LIG_14-3-3_CanoR_1 287 292 PF00244 0.343
LIG_14-3-3_CanoR_1 29 36 PF00244 0.444
LIG_14-3-3_CanoR_1 298 305 PF00244 0.293
LIG_14-3-3_CanoR_1 371 380 PF00244 0.472
LIG_14-3-3_CanoR_1 401 407 PF00244 0.383
LIG_14-3-3_CanoR_1 485 490 PF00244 0.438
LIG_14-3-3_CanoR_1 623 631 PF00244 0.548
LIG_14-3-3_CanoR_1 782 788 PF00244 0.635
LIG_14-3-3_CanoR_1 964 972 PF00244 0.689
LIG_14-3-3_CanoR_1 982 987 PF00244 0.671
LIG_Actin_WH2_2 356 373 PF00022 0.245
LIG_APCC_ABBA_1 458 463 PF00400 0.321
LIG_APCC_ABBA_1 46 51 PF00400 0.332
LIG_BIR_III_2 666 670 PF00653 0.638
LIG_BIR_III_2 880 884 PF00653 0.587
LIG_BRCT_BRCA1_1 1048 1052 PF00533 0.811
LIG_BRCT_BRCA1_1 171 175 PF00533 0.401
LIG_Clathr_ClatBox_1 534 538 PF01394 0.282
LIG_eIF4E_1 337 343 PF01652 0.267
LIG_eIF4E_1 503 509 PF01652 0.269
LIG_eIF4E_1 522 528 PF01652 0.211
LIG_FHA_1 144 150 PF00498 0.399
LIG_FHA_1 284 290 PF00498 0.406
LIG_FHA_1 311 317 PF00498 0.371
LIG_FHA_1 394 400 PF00498 0.360
LIG_FHA_1 417 423 PF00498 0.413
LIG_FHA_1 467 473 PF00498 0.410
LIG_FHA_1 530 536 PF00498 0.305
LIG_FHA_1 613 619 PF00498 0.339
LIG_FHA_1 744 750 PF00498 0.566
LIG_FHA_1 753 759 PF00498 0.500
LIG_FHA_1 77 83 PF00498 0.387
LIG_FHA_1 778 784 PF00498 0.513
LIG_FHA_1 828 834 PF00498 0.510
LIG_FHA_1 94 100 PF00498 0.516
LIG_FHA_2 225 231 PF00498 0.385
LIG_FHA_2 436 442 PF00498 0.375
LIG_FHA_2 57 63 PF00498 0.459
LIG_FHA_2 628 634 PF00498 0.490
LIG_FHA_2 679 685 PF00498 0.505
LIG_FHA_2 720 726 PF00498 0.509
LIG_FHA_2 890 896 PF00498 0.782
LIG_FHA_2 900 906 PF00498 0.823
LIG_FXI_DFP_1 503 507 PF00024 0.452
LIG_GBD_Chelix_1 17 25 PF00786 0.538
LIG_GBD_Chelix_1 317 325 PF00786 0.653
LIG_GBD_Chelix_1 740 748 PF00786 0.409
LIG_KLC1_Yacidic_2 500 505 PF13176 0.254
LIG_LIR_Apic_2 190 194 PF02991 0.451
LIG_LIR_Apic_2 328 333 PF02991 0.378
LIG_LIR_Apic_2 405 411 PF02991 0.466
LIG_LIR_Apic_2 773 779 PF02991 0.489
LIG_LIR_Gen_1 172 182 PF02991 0.290
LIG_LIR_Gen_1 19 28 PF02991 0.438
LIG_LIR_Gen_1 222 233 PF02991 0.490
LIG_LIR_Gen_1 290 301 PF02991 0.401
LIG_LIR_Gen_1 488 494 PF02991 0.350
LIG_LIR_Gen_1 500 511 PF02991 0.424
LIG_LIR_Gen_1 677 688 PF02991 0.506
LIG_LIR_Gen_1 785 795 PF02991 0.563
LIG_LIR_Gen_1 807 817 PF02991 0.604
LIG_LIR_Nem_3 19 23 PF02991 0.445
LIG_LIR_Nem_3 2 6 PF02991 0.338
LIG_LIR_Nem_3 222 228 PF02991 0.403
LIG_LIR_Nem_3 230 236 PF02991 0.398
LIG_LIR_Nem_3 290 296 PF02991 0.426
LIG_LIR_Nem_3 488 492 PF02991 0.342
LIG_LIR_Nem_3 500 506 PF02991 0.437
LIG_LIR_Nem_3 677 683 PF02991 0.506
LIG_LIR_Nem_3 687 693 PF02991 0.609
LIG_LIR_Nem_3 752 756 PF02991 0.527
LIG_LIR_Nem_3 759 765 PF02991 0.507
LIG_LIR_Nem_3 785 791 PF02991 0.506
LIG_LIR_Nem_3 807 813 PF02991 0.523
LIG_LIR_Nem_3 814 820 PF02991 0.484
LIG_LIR_Nem_3 843 849 PF02991 0.520
LIG_LIR_Nem_3 933 939 PF02991 0.695
LIG_LIR_Nem_3 969 975 PF02991 0.614
LIG_LYPXL_yS_3 3 6 PF13949 0.291
LIG_MAD2 280 288 PF02301 0.287
LIG_MYND_3 353 357 PF01753 0.444
LIG_PCNA_yPIPBox_3 142 152 PF02747 0.481
LIG_PCNA_yPIPBox_3 634 642 PF02747 0.260
LIG_PTB_Apo_2 345 352 PF02174 0.477
LIG_PTB_Phospho_1 345 351 PF10480 0.481
LIG_SH2_CRK 191 195 PF00017 0.452
LIG_SH2_CRK 408 412 PF00017 0.484
LIG_SH2_CRK 468 472 PF00017 0.469
LIG_SH2_GRB2like 293 296 PF00017 0.250
LIG_SH2_GRB2like 364 367 PF00017 0.403
LIG_SH2_NCK_1 408 412 PF00017 0.320
LIG_SH2_NCK_1 810 814 PF00017 0.597
LIG_SH2_PTP2 349 352 PF00017 0.444
LIG_SH2_PTP2 776 779 PF00017 0.538
LIG_SH2_SRC 180 183 PF00017 0.472
LIG_SH2_SRC 293 296 PF00017 0.324
LIG_SH2_SRC 776 779 PF00017 0.551
LIG_SH2_SRC 810 813 PF00017 0.597
LIG_SH2_STAP1 312 316 PF00017 0.391
LIG_SH2_STAP1 364 368 PF00017 0.458
LIG_SH2_STAP1 468 472 PF00017 0.295
LIG_SH2_STAP1 50 54 PF00017 0.465
LIG_SH2_STAP1 514 518 PF00017 0.254
LIG_SH2_STAP1 788 792 PF00017 0.564
LIG_SH2_STAT3 207 210 PF00017 0.514
LIG_SH2_STAT3 589 592 PF00017 0.347
LIG_SH2_STAT3 92 95 PF00017 0.292
LIG_SH2_STAT5 180 183 PF00017 0.365
LIG_SH2_STAT5 186 189 PF00017 0.380
LIG_SH2_STAT5 207 210 PF00017 0.474
LIG_SH2_STAT5 235 238 PF00017 0.437
LIG_SH2_STAT5 293 296 PF00017 0.401
LIG_SH2_STAT5 312 315 PF00017 0.479
LIG_SH2_STAT5 330 333 PF00017 0.454
LIG_SH2_STAT5 34 37 PF00017 0.346
LIG_SH2_STAT5 349 352 PF00017 0.366
LIG_SH2_STAT5 468 471 PF00017 0.363
LIG_SH2_STAT5 503 506 PF00017 0.421
LIG_SH2_STAT5 522 525 PF00017 0.338
LIG_SH2_STAT5 657 660 PF00017 0.666
LIG_SH2_STAT5 776 779 PF00017 0.485
LIG_SH3_1 191 197 PF00018 0.345
LIG_SH3_3 1112 1118 PF00018 0.758
LIG_SH3_3 1121 1127 PF00018 0.833
LIG_SH3_3 191 197 PF00018 0.345
LIG_SH3_3 329 335 PF00018 0.378
LIG_SH3_3 411 417 PF00018 0.376
LIG_SH3_3 602 608 PF00018 0.376
LIG_SH3_3 610 616 PF00018 0.357
LIG_SH3_3 954 960 PF00018 0.640
LIG_SUMO_SIM_anti_2 1109 1116 PF11976 0.775
LIG_SUMO_SIM_anti_2 454 460 PF11976 0.356
LIG_SUMO_SIM_anti_2 673 682 PF11976 0.508
LIG_SUMO_SIM_par_1 412 419 PF11976 0.297
LIG_SUMO_SIM_par_1 433 438 PF11976 0.406
LIG_SUMO_SIM_par_1 456 463 PF11976 0.409
LIG_SUMO_SIM_par_1 532 538 PF11976 0.287
LIG_SUMO_SIM_par_1 593 598 PF11976 0.330
LIG_SUMO_SIM_par_1 642 648 PF11976 0.450
LIG_SUMO_SIM_par_1 754 759 PF11976 0.413
LIG_SxIP_EBH_1 75 86 PF03271 0.293
LIG_TRAF2_1 1095 1098 PF00917 0.815
LIG_TRAF2_1 227 230 PF00917 0.297
LIG_TRAF2_1 784 787 PF00917 0.629
LIG_TRAF2_1 850 853 PF00917 0.538
LIG_TYR_ITIM 362 367 PF00017 0.456
LIG_TYR_ITIM 466 471 PF00017 0.422
LIG_TYR_ITIM 808 813 PF00017 0.483
LIG_WRC_WIRS_1 486 491 PF05994 0.560
LIG_WW_3 1036 1040 PF00397 0.859
LIG_WW_3 959 963 PF00397 0.699
MOD_CDK_SPxxK_3 627 634 PF00069 0.538
MOD_CK1_1 1032 1038 PF00069 0.792
MOD_CK1_1 1074 1080 PF00069 0.601
MOD_CK1_1 123 129 PF00069 0.677
MOD_CK1_1 166 172 PF00069 0.425
MOD_CK1_1 242 248 PF00069 0.528
MOD_CK1_1 375 381 PF00069 0.447
MOD_CK1_1 393 399 PF00069 0.394
MOD_CK1_1 402 408 PF00069 0.417
MOD_CK1_1 418 424 PF00069 0.530
MOD_CK1_1 496 502 PF00069 0.541
MOD_CK1_1 520 526 PF00069 0.414
MOD_CK1_1 627 633 PF00069 0.562
MOD_CK1_1 67 73 PF00069 0.650
MOD_CK1_1 733 739 PF00069 0.507
MOD_CK1_1 917 923 PF00069 0.577
MOD_CK2_1 1065 1071 PF00069 0.777
MOD_CK2_1 224 230 PF00069 0.392
MOD_CK2_1 627 633 PF00069 0.657
MOD_CK2_1 678 684 PF00069 0.354
MOD_CK2_1 781 787 PF00069 0.530
MOD_CK2_1 847 853 PF00069 0.363
MOD_CK2_1 889 895 PF00069 0.708
MOD_CK2_1 899 905 PF00069 0.718
MOD_Cter_Amidation 883 886 PF01082 0.546
MOD_GlcNHglycan 1031 1034 PF01048 0.821
MOD_GlcNHglycan 1041 1046 PF01048 0.755
MOD_GlcNHglycan 1073 1076 PF01048 0.585
MOD_GlcNHglycan 1104 1107 PF01048 0.813
MOD_GlcNHglycan 1133 1136 PF01048 0.839
MOD_GlcNHglycan 125 128 PF01048 0.681
MOD_GlcNHglycan 171 174 PF01048 0.321
MOD_GlcNHglycan 221 224 PF01048 0.529
MOD_GlcNHglycan 229 233 PF01048 0.584
MOD_GlcNHglycan 31 34 PF01048 0.549
MOD_GlcNHglycan 377 380 PF01048 0.489
MOD_GlcNHglycan 401 404 PF01048 0.505
MOD_GlcNHglycan 423 426 PF01048 0.471
MOD_GlcNHglycan 452 456 PF01048 0.384
MOD_GlcNHglycan 547 550 PF01048 0.581
MOD_GlcNHglycan 579 582 PF01048 0.515
MOD_GlcNHglycan 626 629 PF01048 0.546
MOD_GlcNHglycan 67 70 PF01048 0.651
MOD_GlcNHglycan 732 735 PF01048 0.448
MOD_GlcNHglycan 908 911 PF01048 0.656
MOD_GlcNHglycan 921 924 PF01048 0.458
MOD_GSK3_1 1037 1044 PF00069 0.824
MOD_GSK3_1 1065 1072 PF00069 0.813
MOD_GSK3_1 1085 1092 PF00069 0.840
MOD_GSK3_1 1102 1109 PF00069 0.689
MOD_GSK3_1 143 150 PF00069 0.425
MOD_GSK3_1 215 222 PF00069 0.586
MOD_GSK3_1 224 231 PF00069 0.428
MOD_GSK3_1 23 30 PF00069 0.524
MOD_GSK3_1 239 246 PF00069 0.560
MOD_GSK3_1 252 259 PF00069 0.430
MOD_GSK3_1 283 290 PF00069 0.479
MOD_GSK3_1 371 378 PF00069 0.478
MOD_GSK3_1 466 473 PF00069 0.538
MOD_GSK3_1 474 481 PF00069 0.530
MOD_GSK3_1 623 630 PF00069 0.568
MOD_GSK3_1 64 71 PF00069 0.617
MOD_GSK3_1 674 681 PF00069 0.371
MOD_GSK3_1 719 726 PF00069 0.362
MOD_GSK3_1 72 79 PF00069 0.608
MOD_GSK3_1 777 784 PF00069 0.511
MOD_GSK3_1 899 906 PF00069 0.643
MOD_GSK3_1 913 920 PF00069 0.666
MOD_GSK3_1 960 967 PF00069 0.686
MOD_N-GLC_1 310 315 PF02516 0.545
MOD_N-GLC_1 520 525 PF02516 0.454
MOD_N-GLC_1 77 82 PF02516 0.446
MOD_NEK2_1 1046 1051 PF00069 0.633
MOD_NEK2_1 143 148 PF00069 0.457
MOD_NEK2_1 164 169 PF00069 0.351
MOD_NEK2_1 264 269 PF00069 0.400
MOD_NEK2_1 289 294 PF00069 0.414
MOD_NEK2_1 399 404 PF00069 0.390
MOD_NEK2_1 435 440 PF00069 0.505
MOD_NEK2_1 466 471 PF00069 0.385
MOD_NEK2_1 65 70 PF00069 0.401
MOD_NEK2_1 914 919 PF00069 0.601
MOD_NEK2_1 93 98 PF00069 0.601
MOD_NEK2_1 930 935 PF00069 0.398
MOD_NEK2_2 34 39 PF00069 0.339
MOD_PIKK_1 72 78 PF00454 0.489
MOD_PIKK_1 984 990 PF00454 0.687
MOD_PK_1 372 378 PF00069 0.560
MOD_PKA_1 1069 1075 PF00069 0.830
MOD_PKA_1 1093 1099 PF00069 0.619
MOD_PKA_1 1102 1108 PF00069 0.560
MOD_PKA_1 371 377 PF00069 0.548
MOD_PKA_2 1029 1035 PF00069 0.832
MOD_PKA_2 1046 1052 PF00069 0.687
MOD_PKA_2 1093 1099 PF00069 0.862
MOD_PKA_2 1102 1108 PF00069 0.811
MOD_PKA_2 28 34 PF00069 0.557
MOD_PKA_2 297 303 PF00069 0.507
MOD_PKA_2 371 377 PF00069 0.529
MOD_PKA_2 781 787 PF00069 0.533
MOD_PKB_1 621 629 PF00069 0.464
MOD_PKB_1 962 970 PF00069 0.735
MOD_Plk_1 390 396 PF00069 0.423
MOD_Plk_1 451 457 PF00069 0.510
MOD_Plk_1 77 83 PF00069 0.511
MOD_Plk_1 99 105 PF00069 0.501
MOD_Plk_2-3 719 725 PF00069 0.352
MOD_Plk_4 154 160 PF00069 0.584
MOD_Plk_4 252 258 PF00069 0.437
MOD_Plk_4 409 415 PF00069 0.308
MOD_Plk_4 523 529 PF00069 0.365
MOD_Plk_4 590 596 PF00069 0.394
MOD_Plk_4 614 620 PF00069 0.436
MOD_Plk_4 674 680 PF00069 0.352
MOD_Plk_4 723 729 PF00069 0.366
MOD_Plk_4 99 105 PF00069 0.602
MOD_ProDKin_1 475 481 PF00069 0.497
MOD_ProDKin_1 520 526 PF00069 0.432
MOD_ProDKin_1 540 546 PF00069 0.282
MOD_ProDKin_1 56 62 PF00069 0.574
MOD_ProDKin_1 612 618 PF00069 0.434
MOD_ProDKin_1 627 633 PF00069 0.663
MOD_ProDKin_1 820 826 PF00069 0.413
MOD_SUMO_rev_2 102 111 PF00179 0.624
TRG_DiLeu_BaEn_1 674 679 PF01217 0.484
TRG_DiLeu_BaEn_2 356 362 PF01217 0.363
TRG_DiLeu_LyEn_5 947 952 PF01217 0.545
TRG_ENDOCYTIC_2 293 296 PF00928 0.357
TRG_ENDOCYTIC_2 3 6 PF00928 0.616
TRG_ENDOCYTIC_2 349 352 PF00928 0.552
TRG_ENDOCYTIC_2 364 367 PF00928 0.500
TRG_ENDOCYTIC_2 468 471 PF00928 0.426
TRG_ENDOCYTIC_2 49 52 PF00928 0.525
TRG_ENDOCYTIC_2 503 506 PF00928 0.594
TRG_ENDOCYTIC_2 657 660 PF00928 0.649
TRG_ENDOCYTIC_2 762 765 PF00928 0.360
TRG_ENDOCYTIC_2 788 791 PF00928 0.344
TRG_ENDOCYTIC_2 810 813 PF00928 0.481
TRG_ER_diArg_1 1052 1054 PF00400 0.829
TRG_ER_diArg_1 130 132 PF00400 0.386
TRG_ER_diArg_1 370 372 PF00400 0.296
TRG_ER_diArg_1 427 429 PF00400 0.617
TRG_ER_diArg_1 620 623 PF00400 0.525
TRG_ER_diArg_1 795 798 PF00400 0.354
TRG_ER_diArg_1 961 964 PF00400 0.703
TRG_ER_diArg_1 990 993 PF00400 0.685
TRG_Pf-PMV_PEXEL_1 706 710 PF00026 0.428

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P457 Leptomonas seymouri 30% 86%
A0A1X0P171 Trypanosomatidae 34% 89%
A0A3Q8IJB0 Leishmania donovani 68% 86%
A0A3R7M6J4 Trypanosoma rangeli 38% 100%
A0A3R7R8G4 Trypanosoma rangeli 32% 100%
A0A3S5H6Z8 Leishmania donovani 68% 86%
A0A3S7WU91 Leishmania donovani 60% 81%
A0A3S7WU94 Leishmania donovani 52% 83%
A0A3S7WU95 Leishmania donovani 67% 82%
A0A3S7XB85 Leishmania donovani 31% 81%
A4H8U6 Leishmania braziliensis 65% 100%
A4H8V5 Leishmania braziliensis 69% 100%
A4H8V8 Leishmania braziliensis 91% 81%
A4HPI4 Leishmania braziliensis 30% 81%
A4HX84 Leishmania infantum 53% 83%
A4HX85 Leishmania infantum 67% 82%
A4HX87 Leishmania infantum 60% 87%
A4HX88 Leishmania infantum 62% 100%
A4IDA6 Leishmania infantum 31% 82%
C9ZM79 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 92%
C9ZM80 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 92%
C9ZM81 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 92%
C9ZM82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 92%
C9ZM83 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 89%
C9ZM86 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 93%
C9ZN26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 90%
C9ZN41 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 93%
C9ZN43 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 95%
C9ZN44 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 93%
C9ZN45 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 93%
C9ZN46 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 93%
C9ZNA5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 93%
C9ZNA6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 95%
C9ZNH3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 89%
C9ZNT1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 92%
C9ZPZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 92%
C9ZQ51 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 92%
C9ZQ89 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 90%
C9ZQ90 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZQ92 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 94%
C9ZTS4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 90%
C9ZTS5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 90%
C9ZTS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 95%
C9ZUE6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 95%
C9ZWQ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 90%
C9ZWU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 94%
C9ZWU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZWY7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 92%
C9ZZQ4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 92%
D0A0U3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 93%
D0A0W7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 91%
D0A0X5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 90%
D0A1S1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 92%
D0A5D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 95%
D0A5D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 92%
D0A5U0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 92%
D0A5U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 92%
D0A7A0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 92%
D0A9R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 94%
D0AAV3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 91%
E8NHJ6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 49% 100%
E9AQY0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 60% 81%
E9AQY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 54% 82%
E9AQY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 66% 82%
E9AQY4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 67% 86%
E9ARD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 54% 83%
E9AT96 Leishmania mexicana (strain MHOM/GT/2001/U1103) 31% 81%
Q25263 Leishmania donovani 68% 86%
Q26721 Trypanosoma brucei brucei 35% 93%
Q27675 Leishmania donovani 52% 83%
Q4Q1A1 Leishmania major 31% 82%
Q4QEH9 Leishmania major 67% 100%
Q4QEI0 Leishmania major 67% 100%
Q4QEI1 Leishmania major 69% 100%
Q4QEI2 Leishmania major 60% 100%
Q4QEI3 Leishmania major 52% 100%
Q99279 Trypanosoma brucei brucei 31% 92%
Q99280 Trypanosoma brucei brucei 34% 93%
V5AYH7 Trypanosoma cruzi 36% 89%
V5B1C8 Trypanosoma cruzi 39% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS