LeishMANIAdb
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ATP pyrophosphate-lyase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP pyrophosphate-lyase
Gene product:
receptor-type adenylate cyclase a
Species:
Leishmania braziliensis
UniProt:
A4H8U6_LEIBR
TriTrypDb:
LbrM.17.0010 , LBRM2903_350042800 *
Length:
1308

Annotations

LeishMANIAdb annotations

Carries an ATP pyrophosphate-lyase domain on its cytoplasmic segment. Likely acts as a receptor for some unknown extracellular stimulus. Extremely expanded kinetoplastid protein family.. Expressed in the insect stage (promastigote) but not in the mammalian host stage of the parasite life cycle.. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 60
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 47, no: 29
NetGPI no yes: 0, no: 76
Cellular components
Term Name Level Count
GO:0016020 membrane 2 70
GO:0110165 cellular anatomical entity 1 76

Expansion

Sequence features

A4H8U6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 75
GO:0006163 purine nucleotide metabolic process 5 75
GO:0006164 purine nucleotide biosynthetic process 6 75
GO:0006171 cAMP biosynthetic process 8 75
GO:0006725 cellular aromatic compound metabolic process 3 75
GO:0006753 nucleoside phosphate metabolic process 4 75
GO:0006793 phosphorus metabolic process 3 75
GO:0006796 phosphate-containing compound metabolic process 4 75
GO:0006807 nitrogen compound metabolic process 2 75
GO:0007165 signal transduction 2 75
GO:0008152 metabolic process 1 75
GO:0009058 biosynthetic process 2 75
GO:0009117 nucleotide metabolic process 5 75
GO:0009150 purine ribonucleotide metabolic process 6 75
GO:0009152 purine ribonucleotide biosynthetic process 7 75
GO:0009165 nucleotide biosynthetic process 6 75
GO:0009187 cyclic nucleotide metabolic process 6 75
GO:0009190 cyclic nucleotide biosynthetic process 7 75
GO:0009259 ribonucleotide metabolic process 5 75
GO:0009260 ribonucleotide biosynthetic process 6 75
GO:0009987 cellular process 1 75
GO:0018130 heterocycle biosynthetic process 4 75
GO:0019438 aromatic compound biosynthetic process 4 75
GO:0019637 organophosphate metabolic process 3 75
GO:0019693 ribose phosphate metabolic process 4 75
GO:0034641 cellular nitrogen compound metabolic process 3 75
GO:0034654 nucleobase-containing compound biosynthetic process 4 75
GO:0035556 intracellular signal transduction 3 75
GO:0044237 cellular metabolic process 2 75
GO:0044238 primary metabolic process 2 75
GO:0044249 cellular biosynthetic process 3 75
GO:0044271 cellular nitrogen compound biosynthetic process 4 75
GO:0044281 small molecule metabolic process 2 75
GO:0046058 cAMP metabolic process 7 75
GO:0046390 ribose phosphate biosynthetic process 5 75
GO:0046483 heterocycle metabolic process 3 75
GO:0050789 regulation of biological process 2 75
GO:0050794 regulation of cellular process 3 75
GO:0052652 cyclic purine nucleotide metabolic process 6 75
GO:0055086 nucleobase-containing small molecule metabolic process 3 75
GO:0065007 biological regulation 1 75
GO:0071704 organic substance metabolic process 2 75
GO:0072521 purine-containing compound metabolic process 4 75
GO:0072522 purine-containing compound biosynthetic process 5 75
GO:0090407 organophosphate biosynthetic process 4 75
GO:1901135 carbohydrate derivative metabolic process 3 75
GO:1901137 carbohydrate derivative biosynthetic process 4 75
GO:1901293 nucleoside phosphate biosynthetic process 5 75
GO:1901360 organic cyclic compound metabolic process 3 75
GO:1901362 organic cyclic compound biosynthetic process 4 75
GO:1901564 organonitrogen compound metabolic process 3 75
GO:1901566 organonitrogen compound biosynthetic process 4 75
GO:1901576 organic substance biosynthetic process 3 75
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 65
GO:0016829 lyase activity 2 65
GO:0004016 adenylate cyclase activity 3 2
GO:0009975 cyclase activity 2 2
GO:0016849 phosphorus-oxygen lyase activity 3 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 172 176 PF00656 0.458
CLV_C14_Caspase3-7 692 696 PF00656 0.362
CLV_C14_Caspase3-7 915 919 PF00656 0.592
CLV_C14_Caspase3-7 976 980 PF00656 0.509
CLV_MEL_PAP_1 1049 1055 PF00089 0.301
CLV_NRD_NRD_1 11 13 PF00675 0.361
CLV_NRD_NRD_1 1139 1141 PF00675 0.436
CLV_NRD_NRD_1 202 204 PF00675 0.610
CLV_NRD_NRD_1 576 578 PF00675 0.507
CLV_NRD_NRD_1 768 770 PF00675 0.522
CLV_PCSK_FUR_1 200 204 PF00082 0.608
CLV_PCSK_KEX2_1 11 13 PF00082 0.389
CLV_PCSK_KEX2_1 1139 1141 PF00082 0.436
CLV_PCSK_KEX2_1 202 204 PF00082 0.611
CLV_PCSK_KEX2_1 307 309 PF00082 0.608
CLV_PCSK_KEX2_1 539 541 PF00082 0.509
CLV_PCSK_KEX2_1 576 578 PF00082 0.483
CLV_PCSK_KEX2_1 600 602 PF00082 0.505
CLV_PCSK_KEX2_1 768 770 PF00082 0.549
CLV_PCSK_PC1ET2_1 307 309 PF00082 0.633
CLV_PCSK_PC1ET2_1 539 541 PF00082 0.528
CLV_PCSK_PC1ET2_1 600 602 PF00082 0.567
CLV_PCSK_SKI1_1 101 105 PF00082 0.695
CLV_PCSK_SKI1_1 1232 1236 PF00082 0.417
CLV_PCSK_SKI1_1 203 207 PF00082 0.617
CLV_PCSK_SKI1_1 280 284 PF00082 0.567
CLV_PCSK_SKI1_1 300 304 PF00082 0.520
CLV_PCSK_SKI1_1 307 311 PF00082 0.502
CLV_PCSK_SKI1_1 337 341 PF00082 0.469
CLV_PCSK_SKI1_1 380 384 PF00082 0.606
CLV_PCSK_SKI1_1 503 507 PF00082 0.600
CLV_PCSK_SKI1_1 698 702 PF00082 0.668
DEG_APCC_DBOX_1 1117 1125 PF00400 0.413
DEG_Nend_Nbox_1 1 3 PF02207 0.482
DOC_CKS1_1 867 872 PF01111 0.415
DOC_CYCLIN_RxL_1 304 314 PF00134 0.263
DOC_CYCLIN_yCln2_LP_2 230 236 PF00134 0.351
DOC_CYCLIN_yCln2_LP_2 662 668 PF00134 0.218
DOC_CYCLIN_yCln2_LP_2 864 870 PF00134 0.424
DOC_MAPK_FxFP_2 487 490 PF00069 0.454
DOC_MAPK_gen_1 200 209 PF00069 0.322
DOC_MAPK_gen_1 599 606 PF00069 0.281
DOC_MAPK_MEF2A_6 181 190 PF00069 0.370
DOC_MAPK_MEF2A_6 503 511 PF00069 0.445
DOC_MAPK_MEF2A_6 683 691 PF00069 0.485
DOC_MAPK_RevD_3 1126 1140 PF00069 0.626
DOC_MAPK_RevD_3 188 203 PF00069 0.263
DOC_MAPK_RevD_3 585 601 PF00069 0.238
DOC_PP1_RVXF_1 200 207 PF00149 0.283
DOC_PP1_RVXF_1 298 304 PF00149 0.438
DOC_PP1_RVXF_1 737 744 PF00149 0.328
DOC_PP2B_LxvP_1 864 867 PF13499 0.492
DOC_PP4_FxxP_1 43 46 PF00568 0.408
DOC_PP4_FxxP_1 487 490 PF00568 0.448
DOC_PP4_FxxP_1 660 663 PF00568 0.422
DOC_PP4_FxxP_1 770 773 PF00568 0.495
DOC_SPAK_OSR1_1 433 437 PF12202 0.249
DOC_USP7_MATH_1 1238 1242 PF00917 0.694
DOC_USP7_MATH_1 1283 1287 PF00917 0.796
DOC_USP7_MATH_1 147 151 PF00917 0.410
DOC_USP7_MATH_1 37 41 PF00917 0.426
DOC_USP7_MATH_1 493 497 PF00917 0.363
DOC_USP7_MATH_1 5 9 PF00917 0.460
DOC_USP7_MATH_1 626 630 PF00917 0.415
DOC_USP7_MATH_1 771 775 PF00917 0.396
DOC_USP7_MATH_1 795 799 PF00917 0.409
DOC_USP7_MATH_1 984 988 PF00917 0.574
DOC_USP7_UBL2_3 80 84 PF12436 0.312
DOC_WW_Pin1_4 326 331 PF00397 0.416
DOC_WW_Pin1_4 356 361 PF00397 0.442
DOC_WW_Pin1_4 42 47 PF00397 0.436
DOC_WW_Pin1_4 512 517 PF00397 0.267
DOC_WW_Pin1_4 585 590 PF00397 0.379
DOC_WW_Pin1_4 678 683 PF00397 0.385
DOC_WW_Pin1_4 750 755 PF00397 0.474
DOC_WW_Pin1_4 757 762 PF00397 0.453
DOC_WW_Pin1_4 774 779 PF00397 0.411
DOC_WW_Pin1_4 866 871 PF00397 0.375
DOC_WW_Pin1_4 881 886 PF00397 0.459
LIG_14-3-3_CanoR_1 1036 1042 PF00244 0.634
LIG_14-3-3_CanoR_1 1218 1225 PF00244 0.679
LIG_14-3-3_CanoR_1 1236 1241 PF00244 0.699
LIG_14-3-3_CanoR_1 171 179 PF00244 0.439
LIG_14-3-3_CanoR_1 286 293 PF00244 0.420
LIG_14-3-3_CanoR_1 380 385 PF00244 0.469
LIG_14-3-3_CanoR_1 540 544 PF00244 0.356
LIG_14-3-3_CanoR_1 545 551 PF00244 0.324
LIG_14-3-3_CanoR_1 576 580 PF00244 0.245
LIG_14-3-3_CanoR_1 635 639 PF00244 0.451
LIG_14-3-3_CanoR_1 669 679 PF00244 0.365
LIG_14-3-3_CanoR_1 698 703 PF00244 0.274
LIG_14-3-3_CanoR_1 739 744 PF00244 0.456
LIG_14-3-3_CanoR_1 812 822 PF00244 0.314
LIG_14-3-3_CanoR_1 877 885 PF00244 0.483
LIG_14-3-3_CterR_2 1304 1308 PF00244 0.669
LIG_AP2alpha_2 664 666 PF02296 0.221
LIG_APCC_ABBA_1 136 141 PF00400 0.441
LIG_APCC_ABBA_1 509 514 PF00400 0.306
LIG_BIR_III_2 1134 1138 PF00653 0.601
LIG_BIR_III_2 920 924 PF00653 0.667
LIG_BRCT_BRCA1_1 175 179 PF00533 0.399
LIG_BRCT_BRCA1_1 352 356 PF00533 0.526
LIG_BRCT_BRCA1_1 39 43 PF00533 0.195
LIG_BRCT_BRCA1_1 649 653 PF00533 0.342
LIG_BRCT_BRCA1_2 649 655 PF00533 0.232
LIG_Clathr_ClatBox_1 510 514 PF01394 0.369
LIG_DLG_GKlike_1 739 746 PF00625 0.284
LIG_eIF4E_1 591 597 PF01652 0.253
LIG_FHA_1 1007 1013 PF00498 0.506
LIG_FHA_1 1032 1038 PF00498 0.518
LIG_FHA_1 1082 1088 PF00498 0.515
LIG_FHA_1 116 122 PF00498 0.454
LIG_FHA_1 143 149 PF00498 0.309
LIG_FHA_1 27 33 PF00498 0.555
LIG_FHA_1 37 43 PF00498 0.446
LIG_FHA_1 504 510 PF00498 0.376
LIG_FHA_1 576 582 PF00498 0.337
LIG_FHA_1 657 663 PF00498 0.332
LIG_FHA_1 671 677 PF00498 0.376
LIG_FHA_1 721 727 PF00498 0.384
LIG_FHA_1 775 781 PF00498 0.437
LIG_FHA_1 800 806 PF00498 0.399
LIG_FHA_1 867 873 PF00498 0.346
LIG_FHA_1 998 1004 PF00498 0.571
LIG_FHA_2 1144 1150 PF00498 0.741
LIG_FHA_2 1154 1160 PF00498 0.739
LIG_FHA_2 170 176 PF00498 0.449
LIG_FHA_2 178 184 PF00498 0.448
LIG_FHA_2 384 390 PF00498 0.338
LIG_FHA_2 646 652 PF00498 0.300
LIG_FHA_2 690 696 PF00498 0.383
LIG_FHA_2 882 888 PF00498 0.421
LIG_FHA_2 933 939 PF00498 0.508
LIG_FHA_2 974 980 PF00498 0.513
LIG_GBD_Chelix_1 274 282 PF00786 0.545
LIG_GBD_Chelix_1 994 1002 PF00786 0.413
LIG_LIR_Apic_2 1027 1033 PF02991 0.494
LIG_LIR_Apic_2 40 46 PF02991 0.357
LIG_LIR_Apic_2 484 490 PF02991 0.441
LIG_LIR_Apic_2 588 594 PF02991 0.384
LIG_LIR_Apic_2 659 663 PF02991 0.424
LIG_LIR_Gen_1 1039 1049 PF02991 0.565
LIG_LIR_Gen_1 1061 1071 PF02991 0.605
LIG_LIR_Gen_1 218 229 PF02991 0.295
LIG_LIR_Gen_1 336 346 PF02991 0.265
LIG_LIR_Gen_1 35 46 PF02991 0.249
LIG_LIR_Gen_1 476 487 PF02991 0.437
LIG_LIR_Gen_1 742 748 PF02991 0.471
LIG_LIR_Gen_1 931 942 PF02991 0.509
LIG_LIR_Nem_3 1006 1010 PF02991 0.530
LIG_LIR_Nem_3 1013 1019 PF02991 0.511
LIG_LIR_Nem_3 1039 1045 PF02991 0.510
LIG_LIR_Nem_3 1061 1067 PF02991 0.534
LIG_LIR_Nem_3 1068 1074 PF02991 0.484
LIG_LIR_Nem_3 1097 1103 PF02991 0.541
LIG_LIR_Nem_3 1187 1193 PF02991 0.646
LIG_LIR_Nem_3 218 224 PF02991 0.315
LIG_LIR_Nem_3 336 341 PF02991 0.274
LIG_LIR_Nem_3 35 41 PF02991 0.241
LIG_LIR_Nem_3 476 482 PF02991 0.368
LIG_LIR_Nem_3 742 746 PF02991 0.470
LIG_LIR_Nem_3 837 843 PF02991 0.465
LIG_LIR_Nem_3 931 937 PF02991 0.509
LIG_LIR_Nem_3 941 947 PF02991 0.610
LIG_MLH1_MIPbox_1 175 179 PF16413 0.418
LIG_MYND_3 607 611 PF01753 0.368
LIG_NRBOX 225 231 PF00104 0.243
LIG_PCNA_yPIPBox_3 128 136 PF02747 0.246
LIG_PCNA_yPIPBox_3 223 231 PF02747 0.234
LIG_PCNA_yPIPBox_3 378 388 PF02747 0.276
LIG_PCNA_yPIPBox_3 888 896 PF02747 0.237
LIG_Pex14_2 44 48 PF04695 0.207
LIG_Pex14_2 615 619 PF04695 0.199
LIG_Pex14_2 766 770 PF04695 0.344
LIG_PTB_Apo_2 63 70 PF02174 0.371
LIG_PTB_Apo_2 89 96 PF02174 0.247
LIG_PTB_Phospho_1 63 69 PF10480 0.379
LIG_PTB_Phospho_1 89 95 PF10480 0.247
LIG_RPA_C_Fungi 281 293 PF08784 0.439
LIG_SH2_CRK 221 225 PF00017 0.475
LIG_SH2_CRK 237 241 PF00017 0.560
LIG_SH2_CRK 591 595 PF00017 0.574
LIG_SH2_GRB2like 840 843 PF00017 0.360
LIG_SH2_NCK_1 1064 1068 PF00017 0.482
LIG_SH2_PTP2 1030 1033 PF00017 0.408
LIG_SH2_PTP2 2 5 PF00017 0.223
LIG_SH2_PTP2 338 341 PF00017 0.321
LIG_SH2_PTP2 603 606 PF00017 0.565
LIG_SH2_SRC 1030 1033 PF00017 0.425
LIG_SH2_SRC 1064 1067 PF00017 0.476
LIG_SH2_SRC 291 294 PF00017 0.558
LIG_SH2_STAP1 1042 1046 PF00017 0.438
LIG_SH2_STAP1 566 570 PF00017 0.456
LIG_SH2_STAP1 69 73 PF00017 0.315
LIG_SH2_STAP1 722 726 PF00017 0.309
LIG_SH2_STAT3 461 464 PF00017 0.541
LIG_SH2_STAT3 843 846 PF00017 0.396
LIG_SH2_STAT5 1030 1033 PF00017 0.331
LIG_SH2_STAT5 1225 1228 PF00017 0.520
LIG_SH2_STAT5 178 181 PF00017 0.416
LIG_SH2_STAT5 2 5 PF00017 0.223
LIG_SH2_STAT5 291 294 PF00017 0.391
LIG_SH2_STAT5 338 341 PF00017 0.324
LIG_SH2_STAT5 349 352 PF00017 0.347
LIG_SH2_STAT5 440 443 PF00017 0.389
LIG_SH2_STAT5 455 458 PF00017 0.504
LIG_SH2_STAT5 461 464 PF00017 0.485
LIG_SH2_STAT5 591 594 PF00017 0.534
LIG_SH2_STAT5 603 606 PF00017 0.450
LIG_SH2_STAT5 618 621 PF00017 0.303
LIG_SH2_STAT5 63 66 PF00017 0.502
LIG_SH2_STAT5 722 725 PF00017 0.372
LIG_SH2_STAT5 911 914 PF00017 0.412
LIG_SH3_3 1208 1214 PF00018 0.532
LIG_SH3_3 132 138 PF00018 0.388
LIG_SH3_3 568 574 PF00018 0.514
LIG_SH3_3 583 589 PF00018 0.460
LIG_SH3_3 794 800 PF00018 0.426
LIG_SH3_3 818 824 PF00018 0.428
LIG_SH3_3 856 862 PF00018 0.476
LIG_SH3_3 864 870 PF00018 0.452
LIG_Sin3_3 30 37 PF02671 0.509
LIG_SUMO_SIM_anti_2 150 157 PF11976 0.389
LIG_SUMO_SIM_anti_2 506 512 PF11976 0.433
LIG_SUMO_SIM_anti_2 567 572 PF11976 0.599
LIG_SUMO_SIM_anti_2 927 936 PF11976 0.361
LIG_SUMO_SIM_par_1 1008 1013 PF11976 0.223
LIG_SUMO_SIM_par_1 144 150 PF11976 0.338
LIG_SUMO_SIM_par_1 262 268 PF11976 0.345
LIG_SUMO_SIM_par_1 896 902 PF11976 0.453
LIG_TRAF2_1 1038 1041 PF00917 0.525
LIG_TRAF2_1 1104 1107 PF00917 0.402
LIG_TYR_ITIM 1062 1067 PF00017 0.485
LIG_TYR_ITIM 219 224 PF00017 0.422
LIG_TYR_ITIM 616 621 PF00017 0.431
LIG_UBA3_1 122 131 PF00899 0.435
LIG_UBA3_1 185 189 PF00899 0.549
LIG_UBA3_1 301 307 PF00899 0.426
LIG_UBA3_1 470 475 PF00899 0.544
LIG_UBA3_1 509 517 PF00899 0.278
LIG_UBA3_1 614 620 PF00899 0.478
LIG_WRC_WIRS_1 384 389 PF05994 0.301
LIG_WRC_WIRS_1 699 704 PF05994 0.511
LIG_WRC_WIRS_1 740 745 PF05994 0.587
LIG_WW_3 1213 1217 PF00397 0.663
LIG_WW_3 1290 1294 PF00397 0.499
MOD_CDK_SPK_2 512 517 PF00069 0.222
MOD_CDK_SPK_2 678 683 PF00069 0.269
MOD_CDK_SPxxK_3 757 764 PF00069 0.556
MOD_CDK_SPxxK_3 881 888 PF00069 0.440
MOD_CK1_1 1171 1177 PF00069 0.483
MOD_CK1_1 1286 1292 PF00069 0.679
MOD_CK1_1 285 291 PF00069 0.391
MOD_CK1_1 314 320 PF00069 0.530
MOD_CK1_1 329 335 PF00069 0.579
MOD_CK1_1 485 491 PF00069 0.467
MOD_CK1_1 629 635 PF00069 0.431
MOD_CK1_1 735 741 PF00069 0.413
MOD_CK1_1 742 748 PF00069 0.506
MOD_CK1_1 750 756 PF00069 0.562
MOD_CK1_1 774 780 PF00069 0.478
MOD_CK1_1 813 819 PF00069 0.384
MOD_CK1_1 881 887 PF00069 0.485
MOD_CK1_1 987 993 PF00069 0.507
MOD_CK2_1 1035 1041 PF00069 0.527
MOD_CK2_1 1101 1107 PF00069 0.366
MOD_CK2_1 1143 1149 PF00069 0.666
MOD_CK2_1 1153 1159 PF00069 0.618
MOD_CK2_1 177 183 PF00069 0.542
MOD_CK2_1 322 328 PF00069 0.503
MOD_CK2_1 383 389 PF00069 0.423
MOD_CK2_1 494 500 PF00069 0.313
MOD_CK2_1 639 645 PF00069 0.455
MOD_CK2_1 881 887 PF00069 0.558
MOD_CK2_1 932 938 PF00069 0.358
MOD_Cter_Amidation 1137 1140 PF01082 0.531
MOD_GlcNHglycan 1162 1165 PF01048 0.574
MOD_GlcNHglycan 1175 1178 PF01048 0.369
MOD_GlcNHglycan 1285 1288 PF01048 0.677
MOD_GlcNHglycan 1293 1296 PF01048 0.719
MOD_GlcNHglycan 1297 1300 PF01048 0.737
MOD_GlcNHglycan 241 244 PF01048 0.448
MOD_GlcNHglycan 288 291 PF01048 0.518
MOD_GlcNHglycan 311 314 PF01048 0.517
MOD_GlcNHglycan 324 327 PF01048 0.633
MOD_GlcNHglycan 351 355 PF01048 0.403
MOD_GlcNHglycan 373 376 PF01048 0.629
MOD_GlcNHglycan 403 406 PF01048 0.504
MOD_GlcNHglycan 421 424 PF01048 0.557
MOD_GlcNHglycan 491 494 PF01048 0.443
MOD_GlcNHglycan 628 631 PF01048 0.459
MOD_GlcNHglycan 641 644 PF01048 0.479
MOD_GlcNHglycan 7 10 PF01048 0.427
MOD_GlcNHglycan 833 836 PF01048 0.429
MOD_GlcNHglycan 880 883 PF01048 0.593
MOD_GlcNHglycan 92 95 PF01048 0.396
MOD_GlcNHglycan 986 989 PF01048 0.452
MOD_GSK3_1 1031 1038 PF00069 0.511
MOD_GSK3_1 111 118 PF00069 0.471
MOD_GSK3_1 1153 1160 PF00069 0.535
MOD_GSK3_1 1167 1174 PF00069 0.579
MOD_GSK3_1 1214 1221 PF00069 0.635
MOD_GSK3_1 1291 1298 PF00069 0.754
MOD_GSK3_1 162 169 PF00069 0.407
MOD_GSK3_1 173 180 PF00069 0.480
MOD_GSK3_1 22 29 PF00069 0.496
MOD_GSK3_1 280 287 PF00069 0.504
MOD_GSK3_1 32 39 PF00069 0.465
MOD_GSK3_1 322 329 PF00069 0.609
MOD_GSK3_1 352 359 PF00069 0.584
MOD_GSK3_1 364 371 PF00069 0.657
MOD_GSK3_1 376 383 PF00069 0.562
MOD_GSK3_1 485 492 PF00069 0.388
MOD_GSK3_1 544 551 PF00069 0.399
MOD_GSK3_1 581 588 PF00069 0.382
MOD_GSK3_1 64 71 PF00069 0.378
MOD_GSK3_1 670 677 PF00069 0.443
MOD_GSK3_1 694 701 PF00069 0.516
MOD_GSK3_1 727 734 PF00069 0.489
MOD_GSK3_1 735 742 PF00069 0.440
MOD_GSK3_1 795 802 PF00069 0.457
MOD_GSK3_1 810 817 PF00069 0.413
MOD_GSK3_1 827 834 PF00069 0.464
MOD_GSK3_1 862 869 PF00069 0.491
MOD_GSK3_1 877 884 PF00069 0.485
MOD_GSK3_1 928 935 PF00069 0.375
MOD_GSK3_1 973 980 PF00069 0.360
MOD_N-GLC_1 115 120 PF02516 0.330
MOD_N-GLC_1 380 385 PF02516 0.372
MOD_N-GLC_1 494 499 PF02516 0.551
MOD_N-GLC_1 564 569 PF02516 0.500
MOD_N-GLC_1 774 779 PF02516 0.509
MOD_NEK2_1 1168 1173 PF00069 0.522
MOD_NEK2_1 1184 1189 PF00069 0.312
MOD_NEK2_1 164 169 PF00069 0.491
MOD_NEK2_1 207 212 PF00069 0.486
MOD_NEK2_1 222 227 PF00069 0.428
MOD_NEK2_1 256 261 PF00069 0.413
MOD_NEK2_1 282 287 PF00069 0.428
MOD_NEK2_1 309 314 PF00069 0.358
MOD_NEK2_1 32 37 PF00069 0.460
MOD_NEK2_1 456 461 PF00069 0.498
MOD_NEK2_1 546 551 PF00069 0.409
MOD_NEK2_1 64 69 PF00069 0.333
MOD_NEK2_1 653 658 PF00069 0.389
MOD_NEK2_1 672 677 PF00069 0.289
MOD_NEK2_1 811 816 PF00069 0.331
MOD_NEK2_1 90 95 PF00069 0.352
MOD_NEK2_2 166 171 PF00069 0.508
MOD_NEK2_2 173 178 PF00069 0.536
MOD_PIKK_1 1238 1244 PF00454 0.641
MOD_PIKK_1 22 28 PF00454 0.247
MOD_PIKK_1 341 347 PF00454 0.449
MOD_PIKK_1 799 805 PF00454 0.384
MOD_PK_1 539 545 PF00069 0.317
MOD_PKA_1 539 545 PF00069 0.514
MOD_PKA_2 1035 1041 PF00069 0.528
MOD_PKA_2 1283 1289 PF00069 0.739
MOD_PKA_2 285 291 PF00069 0.508
MOD_PKA_2 539 545 PF00069 0.455
MOD_PKA_2 575 581 PF00069 0.410
MOD_PKA_2 634 640 PF00069 0.504
MOD_PKA_2 811 817 PF00069 0.258
MOD_PKB_1 1216 1224 PF00069 0.699
MOD_PKB_1 378 386 PF00069 0.317
MOD_PKB_1 875 883 PF00069 0.396
MOD_Plk_1 361 367 PF00069 0.438
MOD_Plk_1 380 386 PF00069 0.311
MOD_Plk_1 475 481 PF00069 0.462
MOD_Plk_1 564 570 PF00069 0.490
MOD_Plk_2-3 361 367 PF00069 0.607
MOD_Plk_2-3 645 651 PF00069 0.515
MOD_Plk_2-3 973 979 PF00069 0.358
MOD_Plk_4 173 179 PF00069 0.445
MOD_Plk_4 225 231 PF00069 0.457
MOD_Plk_4 293 299 PF00069 0.443
MOD_Plk_4 311 317 PF00069 0.384
MOD_Plk_4 368 374 PF00069 0.632
MOD_Plk_4 37 43 PF00069 0.277
MOD_Plk_4 383 389 PF00069 0.554
MOD_Plk_4 403 409 PF00069 0.555
MOD_Plk_4 44 50 PF00069 0.252
MOD_Plk_4 469 475 PF00069 0.464
MOD_Plk_4 482 488 PF00069 0.399
MOD_Plk_4 503 509 PF00069 0.465
MOD_Plk_4 581 587 PF00069 0.361
MOD_Plk_4 64 70 PF00069 0.209
MOD_Plk_4 698 704 PF00069 0.495
MOD_Plk_4 776 782 PF00069 0.458
MOD_Plk_4 785 791 PF00069 0.370
MOD_Plk_4 868 874 PF00069 0.441
MOD_Plk_4 928 934 PF00069 0.356
MOD_Plk_4 977 983 PF00069 0.360
MOD_ProDKin_1 326 332 PF00069 0.503
MOD_ProDKin_1 356 362 PF00069 0.543
MOD_ProDKin_1 42 48 PF00069 0.436
MOD_ProDKin_1 512 518 PF00069 0.301
MOD_ProDKin_1 585 591 PF00069 0.455
MOD_ProDKin_1 678 684 PF00069 0.467
MOD_ProDKin_1 750 756 PF00069 0.589
MOD_ProDKin_1 757 763 PF00069 0.564
MOD_ProDKin_1 774 780 PF00069 0.501
MOD_ProDKin_1 866 872 PF00069 0.448
MOD_ProDKin_1 881 887 PF00069 0.564
MOD_SUMO_for_1 154 157 PF00179 0.294
MOD_SUMO_rev_2 183 191 PF00179 0.526
MOD_SUMO_rev_2 72 82 PF00179 0.319
TRG_DiLeu_BaEn_1 60 65 PF01217 0.521
TRG_DiLeu_BaEn_1 928 933 PF01217 0.486
TRG_DiLeu_BaEn_2 610 616 PF01217 0.360
TRG_DiLeu_BaLyEn_6 305 310 PF01217 0.513
TRG_DiLeu_BaLyEn_6 736 741 PF01217 0.314
TRG_DiLeu_LyEn_5 1201 1206 PF01217 0.548
TRG_ENDOCYTIC_2 1016 1019 PF00928 0.366
TRG_ENDOCYTIC_2 1042 1045 PF00928 0.346
TRG_ENDOCYTIC_2 1064 1067 PF00928 0.482
TRG_ENDOCYTIC_2 221 224 PF00928 0.491
TRG_ENDOCYTIC_2 338 341 PF00928 0.324
TRG_ENDOCYTIC_2 603 606 PF00928 0.560
TRG_ENDOCYTIC_2 618 621 PF00928 0.464
TRG_ENDOCYTIC_2 722 725 PF00928 0.387
TRG_ENDOCYTIC_2 911 914 PF00928 0.482
TRG_ER_diArg_1 1049 1052 PF00400 0.359
TRG_ER_diArg_1 1215 1218 PF00400 0.689
TRG_ER_diArg_1 1244 1247 PF00400 0.668
TRG_ER_diArg_1 199 202 PF00400 0.479
TRG_ER_diArg_1 377 380 PF00400 0.326
TRG_ER_diArg_1 575 577 PF00400 0.390
TRG_ER_diArg_1 768 770 PF00400 0.423
TRG_ER_diArg_1 874 877 PF00400 0.514
TRG_Pf-PMV_PEXEL_1 960 964 PF00026 0.431

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P457 Leptomonas seymouri 26% 99%
A0A1X0NPQ6 Trypanosomatidae 30% 100%
A0A1X0P171 Trypanosomatidae 33% 100%
A0A3Q8IJB0 Leishmania donovani 54% 98%
A0A3R7M6J4 Trypanosoma rangeli 37% 100%
A0A3R7R8G4 Trypanosoma rangeli 31% 100%
A0A3S5H6Z8 Leishmania donovani 54% 98%
A0A3S7WU91 Leishmania donovani 55% 93%
A0A3S7WU94 Leishmania donovani 68% 95%
A0A3S7WU95 Leishmania donovani 54% 93%
A0A3S7XB85 Leishmania donovani 30% 93%
A4H8V5 Leishmania braziliensis 68% 100%
A4H8V7 Leishmania braziliensis 65% 100%
A4H8V8 Leishmania braziliensis 64% 93%
A4HPI4 Leishmania braziliensis 27% 93%
A4HX84 Leishmania infantum 68% 95%
A4HX85 Leishmania infantum 55% 93%
A4HX87 Leishmania infantum 56% 99%
A4HX88 Leishmania infantum 42% 100%
A4IDA6 Leishmania infantum 30% 93%
C9ZM79 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZM80 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZM81 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZM82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZM83 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM86 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZN26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN41 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN43 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZN44 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN45 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN46 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZNA5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZNA6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZNH3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZNT1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZPZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ51 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ89 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZQ90 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ91 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 24% 100%
C9ZQ92 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZTS4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZTS5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZTS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZUE6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWQ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZWY7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZZQ4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
D0A0U3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A0W7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A0X5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A1S1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
D0A5D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5U0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A7A0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A9R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0AAV3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
E9AQY0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 56% 93%
E9AQY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 66% 94%
E9AQY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 54% 93%
E9AQY4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 54% 98%
E9ARD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 66% 95%
E9AT96 Leishmania mexicana (strain MHOM/GT/2001/U1103) 30% 93%
Q25263 Leishmania donovani 55% 98%
Q26721 Trypanosoma brucei brucei 34% 100%
Q27675 Leishmania donovani 68% 95%
Q4Q1A1 Leishmania major 29% 100%
Q4QEH9 Leishmania major 54% 100%
Q4QEI0 Leishmania major 54% 100%
Q4QEI1 Leishmania major 55% 100%
Q4QEI2 Leishmania major 55% 100%
Q4QEI3 Leishmania major 66% 100%
Q99279 Trypanosoma brucei brucei 29% 100%
Q99280 Trypanosoma brucei brucei 31% 100%
V5AYH7 Trypanosoma cruzi 34% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS