LeishMANIAdb
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DNA polymerase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
DNA polymerase
Gene product:
DNA polymerase I alpha catalytic subunit, putative
Species:
Leishmania braziliensis
UniProt:
A4H8T3_LEIBR
TriTrypDb:
LbrM.16.1600 , LBRM2903_160024000 *
Length:
1341

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 11
GO:0043226 organelle 2 11
GO:0043227 membrane-bounded organelle 3 11
GO:0043229 intracellular organelle 3 11
GO:0043231 intracellular membrane-bounded organelle 4 11
GO:0110165 cellular anatomical entity 1 11
GO:0000428 DNA-directed RNA polymerase complex 4 1
GO:0005658 alpha DNA polymerase:primase complex 4 1
GO:0030880 RNA polymerase complex 3 1
GO:0032991 protein-containing complex 1 1
GO:0042575 DNA polymerase complex 3 1
GO:0055029 nuclear DNA-directed RNA polymerase complex 3 1
GO:0061695 transferase complex, transferring phosphorus-containing groups 4 1
GO:0140513 nuclear protein-containing complex 2 1
GO:0140535 intracellular protein-containing complex 2 1
GO:1902494 catalytic complex 2 1
GO:1990234 transferase complex 3 1

Expansion

Sequence features

A4H8T3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 12
GO:0006259 DNA metabolic process 4 12
GO:0006270 DNA replication initiation 5 12
GO:0006725 cellular aromatic compound metabolic process 3 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009987 cellular process 1 12
GO:0022402 cell cycle process 2 12
GO:0034641 cellular nitrogen compound metabolic process 3 12
GO:0043170 macromolecule metabolic process 3 12
GO:0044237 cellular metabolic process 2 12
GO:0044238 primary metabolic process 2 12
GO:0044260 obsolete cellular macromolecule metabolic process 3 12
GO:0046483 heterocycle metabolic process 3 12
GO:0071704 organic substance metabolic process 2 12
GO:0090304 nucleic acid metabolic process 4 12
GO:1901360 organic cyclic compound metabolic process 3 12
GO:1902292 cell cycle DNA replication initiation 3 12
GO:1902315 nuclear cell cycle DNA replication initiation 4 12
GO:1902975 mitotic DNA replication initiation 4 12
GO:1903047 mitotic cell cycle process 3 12
GO:0006271 DNA strand elongation involved in DNA replication 6 1
GO:0006272 leading strand elongation 7 1
GO:0006273 lagging strand elongation 7 1
GO:0022616 DNA strand elongation 5 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 12
GO:0003676 nucleic acid binding 3 12
GO:0003677 DNA binding 4 12
GO:0003824 catalytic activity 1 12
GO:0003887 DNA-directed DNA polymerase activity 5 12
GO:0005488 binding 1 12
GO:0016740 transferase activity 2 12
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 12
GO:0016779 nucleotidyltransferase activity 4 12
GO:0034061 DNA polymerase activity 4 12
GO:0036094 small molecule binding 2 12
GO:0097159 organic cyclic compound binding 2 12
GO:0140097 catalytic activity, acting on DNA 3 12
GO:0140640 catalytic activity, acting on a nucleic acid 2 12
GO:1901265 nucleoside phosphate binding 3 12
GO:1901363 heterocyclic compound binding 2 12
GO:0003682 chromatin binding 2 1
GO:0003688 DNA replication origin binding 7 1
GO:0003690 double-stranded DNA binding 5 1
GO:0003697 single-stranded DNA binding 5 1
GO:0017076 purine nucleotide binding 4 1
GO:0019103 pyrimidine nucleotide binding 4 1
GO:0043565 sequence-specific DNA binding 5 1
GO:1990837 sequence-specific double-stranded DNA binding 6 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 815 819 PF00656 0.379
CLV_C14_Caspase3-7 829 833 PF00656 0.313
CLV_MEL_PAP_1 987 993 PF00089 0.333
CLV_NRD_NRD_1 1062 1064 PF00675 0.303
CLV_NRD_NRD_1 1217 1219 PF00675 0.456
CLV_NRD_NRD_1 1286 1288 PF00675 0.375
CLV_NRD_NRD_1 1293 1295 PF00675 0.338
CLV_NRD_NRD_1 15 17 PF00675 0.683
CLV_NRD_NRD_1 323 325 PF00675 0.326
CLV_NRD_NRD_1 384 386 PF00675 0.424
CLV_NRD_NRD_1 506 508 PF00675 0.388
CLV_NRD_NRD_1 545 547 PF00675 0.420
CLV_NRD_NRD_1 65 67 PF00675 0.506
CLV_NRD_NRD_1 68 70 PF00675 0.539
CLV_NRD_NRD_1 728 730 PF00675 0.304
CLV_NRD_NRD_1 820 822 PF00675 0.303
CLV_NRD_NRD_1 981 983 PF00675 0.301
CLV_PCSK_KEX2_1 100 102 PF00082 0.585
CLV_PCSK_KEX2_1 1286 1288 PF00082 0.389
CLV_PCSK_KEX2_1 1293 1295 PF00082 0.358
CLV_PCSK_KEX2_1 1325 1327 PF00082 0.334
CLV_PCSK_KEX2_1 161 163 PF00082 0.534
CLV_PCSK_KEX2_1 323 325 PF00082 0.319
CLV_PCSK_KEX2_1 384 386 PF00082 0.362
CLV_PCSK_KEX2_1 506 508 PF00082 0.344
CLV_PCSK_KEX2_1 545 547 PF00082 0.416
CLV_PCSK_KEX2_1 564 566 PF00082 0.146
CLV_PCSK_KEX2_1 671 673 PF00082 0.329
CLV_PCSK_KEX2_1 717 719 PF00082 0.337
CLV_PCSK_KEX2_1 728 730 PF00082 0.304
CLV_PCSK_KEX2_1 820 822 PF00082 0.303
CLV_PCSK_KEX2_1 824 826 PF00082 0.303
CLV_PCSK_KEX2_1 931 933 PF00082 0.424
CLV_PCSK_KEX2_1 981 983 PF00082 0.308
CLV_PCSK_KEX2_1 989 991 PF00082 0.301
CLV_PCSK_PC1ET2_1 100 102 PF00082 0.585
CLV_PCSK_PC1ET2_1 1325 1327 PF00082 0.403
CLV_PCSK_PC1ET2_1 161 163 PF00082 0.534
CLV_PCSK_PC1ET2_1 384 386 PF00082 0.362
CLV_PCSK_PC1ET2_1 564 566 PF00082 0.360
CLV_PCSK_PC1ET2_1 671 673 PF00082 0.329
CLV_PCSK_PC1ET2_1 717 719 PF00082 0.337
CLV_PCSK_PC1ET2_1 728 730 PF00082 0.319
CLV_PCSK_PC1ET2_1 824 826 PF00082 0.303
CLV_PCSK_PC1ET2_1 931 933 PF00082 0.424
CLV_PCSK_PC1ET2_1 989 991 PF00082 0.287
CLV_PCSK_PC7_1 560 566 PF00082 0.319
CLV_PCSK_PC7_1 820 826 PF00082 0.303
CLV_PCSK_SKI1_1 1037 1041 PF00082 0.319
CLV_PCSK_SKI1_1 1184 1188 PF00082 0.441
CLV_PCSK_SKI1_1 1262 1266 PF00082 0.327
CLV_PCSK_SKI1_1 292 296 PF00082 0.366
CLV_PCSK_SKI1_1 323 327 PF00082 0.360
CLV_PCSK_SKI1_1 345 349 PF00082 0.203
CLV_PCSK_SKI1_1 385 389 PF00082 0.227
CLV_PCSK_SKI1_1 475 479 PF00082 0.333
CLV_PCSK_SKI1_1 512 516 PF00082 0.319
CLV_PCSK_SKI1_1 671 675 PF00082 0.343
CLV_PCSK_SKI1_1 683 687 PF00082 0.319
CLV_PCSK_SKI1_1 705 709 PF00082 0.303
CLV_PCSK_SKI1_1 729 733 PF00082 0.392
CLV_PCSK_SKI1_1 806 810 PF00082 0.303
CLV_PCSK_SKI1_1 811 815 PF00082 0.303
CLV_PCSK_SKI1_1 821 825 PF00082 0.303
CLV_PCSK_SKI1_1 844 848 PF00082 0.319
CLV_PCSK_SKI1_1 878 882 PF00082 0.303
CLV_PCSK_SKI1_1 945 949 PF00082 0.303
CLV_PCSK_SKI1_1 97 101 PF00082 0.549
CLV_PCSK_SKI1_1 972 976 PF00082 0.313
CLV_Separin_Metazoa 1065 1069 PF03568 0.424
DEG_APCC_DBOX_1 1062 1070 PF00400 0.424
DEG_APCC_DBOX_1 511 519 PF00400 0.308
DEG_APCC_DBOX_1 559 567 PF00400 0.424
DEG_SCF_FBW7_1 193 198 PF00400 0.463
DEG_SCF_FBW7_2 219 224 PF00400 0.366
DOC_CKS1_1 1185 1190 PF01111 0.467
DOC_CKS1_1 18 23 PF01111 0.454
DOC_CKS1_1 631 636 PF01111 0.541
DOC_CKS1_1 706 711 PF01111 0.303
DOC_CYCLIN_RxL_1 1259 1266 PF00134 0.331
DOC_CYCLIN_RxL_1 841 852 PF00134 0.319
DOC_CYCLIN_yCln2_LP_2 1185 1191 PF00134 0.435
DOC_MAPK_gen_1 100 110 PF00069 0.554
DOC_MAPK_gen_1 1061 1069 PF00069 0.303
DOC_MAPK_gen_1 1206 1215 PF00069 0.416
DOC_MAPK_gen_1 1325 1332 PF00069 0.330
DOC_MAPK_gen_1 384 395 PF00069 0.338
DOC_MAPK_gen_1 545 552 PF00069 0.424
DOC_MAPK_gen_1 689 698 PF00069 0.303
DOC_MAPK_gen_1 728 739 PF00069 0.305
DOC_MAPK_gen_1 775 783 PF00069 0.334
DOC_MAPK_gen_1 828 838 PF00069 0.384
DOC_MAPK_gen_1 916 925 PF00069 0.376
DOC_MAPK_gen_1 928 938 PF00069 0.328
DOC_MAPK_gen_1 951 960 PF00069 0.303
DOC_MAPK_MEF2A_6 1206 1215 PF00069 0.472
DOC_MAPK_MEF2A_6 1325 1334 PF00069 0.314
DOC_MAPK_MEF2A_6 481 489 PF00069 0.198
DOC_MAPK_MEF2A_6 641 650 PF00069 0.406
DOC_MAPK_MEF2A_6 916 925 PF00069 0.387
DOC_MAPK_MEF2A_6 931 940 PF00069 0.206
DOC_MAPK_RevD_3 938 954 PF00069 0.303
DOC_PP1_RVXF_1 321 328 PF00149 0.319
DOC_PP2B_LxvP_1 427 430 PF13499 0.424
DOC_PP2B_LxvP_1 53 56 PF13499 0.576
DOC_PP2B_LxvP_1 799 802 PF13499 0.392
DOC_PP4_FxxP_1 1265 1268 PF00568 0.329
DOC_PP4_FxxP_1 295 298 PF00568 0.319
DOC_PP4_FxxP_1 334 337 PF00568 0.303
DOC_PP4_FxxP_1 706 709 PF00568 0.303
DOC_USP7_MATH_1 1002 1006 PF00917 0.424
DOC_USP7_MATH_1 188 192 PF00917 0.588
DOC_USP7_MATH_1 195 199 PF00917 0.475
DOC_USP7_MATH_1 231 235 PF00917 0.608
DOC_USP7_MATH_1 373 377 PF00917 0.303
DOC_USP7_MATH_1 400 404 PF00917 0.198
DOC_USP7_MATH_1 627 631 PF00917 0.563
DOC_USP7_MATH_1 659 663 PF00917 0.439
DOC_USP7_MATH_1 880 884 PF00917 0.424
DOC_USP7_UBL2_3 1037 1041 PF12436 0.303
DOC_USP7_UBL2_3 384 388 PF12436 0.388
DOC_USP7_UBL2_3 63 67 PF12436 0.532
DOC_USP7_UBL2_3 728 732 PF12436 0.305
DOC_USP7_UBL2_3 76 80 PF12436 0.640
DOC_USP7_UBL2_3 824 828 PF12436 0.303
DOC_USP7_UBL2_3 912 916 PF12436 0.388
DOC_USP7_UBL2_3 968 972 PF12436 0.310
DOC_WW_Pin1_4 1184 1189 PF00397 0.465
DOC_WW_Pin1_4 149 154 PF00397 0.512
DOC_WW_Pin1_4 17 22 PF00397 0.608
DOC_WW_Pin1_4 191 196 PF00397 0.686
DOC_WW_Pin1_4 205 210 PF00397 0.668
DOC_WW_Pin1_4 217 222 PF00397 0.615
DOC_WW_Pin1_4 413 418 PF00397 0.282
DOC_WW_Pin1_4 630 635 PF00397 0.551
DOC_WW_Pin1_4 705 710 PF00397 0.303
LIG_14-3-3_CanoR_1 1047 1052 PF00244 0.273
LIG_14-3-3_CanoR_1 1082 1090 PF00244 0.420
LIG_14-3-3_CanoR_1 1094 1101 PF00244 0.251
LIG_14-3-3_CanoR_1 1218 1222 PF00244 0.455
LIG_14-3-3_CanoR_1 1255 1261 PF00244 0.325
LIG_14-3-3_CanoR_1 1293 1299 PF00244 0.382
LIG_14-3-3_CanoR_1 277 281 PF00244 0.517
LIG_14-3-3_CanoR_1 481 486 PF00244 0.387
LIG_14-3-3_CanoR_1 605 610 PF00244 0.486
LIG_14-3-3_CanoR_1 672 680 PF00244 0.330
LIG_14-3-3_CanoR_1 932 937 PF00244 0.319
LIG_14-3-3_CanoR_1 990 996 PF00244 0.295
LIG_Actin_WH2_2 380 396 PF00022 0.424
LIG_Actin_WH2_2 690 707 PF00022 0.303
LIG_Actin_WH2_2 832 849 PF00022 0.303
LIG_Actin_WH2_2 881 898 PF00022 0.338
LIG_APCC_ABBA_1 457 462 PF00400 0.338
LIG_APCC_ABBAyCdc20_2 742 748 PF00400 0.303
LIG_BRCT_BRCA1_1 1157 1161 PF00533 0.438
LIG_BRCT_BRCA1_1 176 180 PF00533 0.561
LIG_CaM_NSCaTE_8 681 688 PF13499 0.338
LIG_CtBP_PxDLS_1 976 982 PF00389 0.303
LIG_eIF4E_1 291 297 PF01652 0.239
LIG_eIF4E_1 746 752 PF01652 0.303
LIG_EVH1_1 427 431 PF00568 0.424
LIG_FHA_1 1053 1059 PF00498 0.388
LIG_FHA_1 109 115 PF00498 0.371
LIG_FHA_1 152 158 PF00498 0.497
LIG_FHA_1 254 260 PF00498 0.348
LIG_FHA_1 627 633 PF00498 0.528
LIG_FHA_1 656 662 PF00498 0.389
LIG_FHA_1 668 674 PF00498 0.253
LIG_FHA_1 882 888 PF00498 0.317
LIG_FHA_1 900 906 PF00498 0.227
LIG_FHA_2 1027 1033 PF00498 0.333
LIG_FHA_2 1295 1301 PF00498 0.403
LIG_FHA_2 136 142 PF00498 0.530
LIG_FHA_2 145 151 PF00498 0.490
LIG_FHA_2 192 198 PF00498 0.626
LIG_FHA_2 698 704 PF00498 0.424
LIG_FHA_2 769 775 PF00498 0.319
LIG_FHA_2 827 833 PF00498 0.301
LIG_FHA_2 957 963 PF00498 0.388
LIG_Integrin_isoDGR_2 275 277 PF01839 0.530
LIG_IRF3_LxIS_1 390 396 PF10401 0.450
LIG_LIR_Apic_2 293 298 PF02991 0.364
LIG_LIR_Apic_2 703 709 PF02991 0.388
LIG_LIR_Gen_1 1328 1339 PF02991 0.327
LIG_LIR_Gen_1 344 352 PF02991 0.388
LIG_LIR_Gen_1 391 400 PF02991 0.327
LIG_LIR_Gen_1 553 563 PF02991 0.426
LIG_LIR_Gen_1 642 650 PF02991 0.406
LIG_LIR_Gen_1 694 701 PF02991 0.303
LIG_LIR_Gen_1 747 755 PF02991 0.303
LIG_LIR_Gen_1 860 869 PF02991 0.351
LIG_LIR_Nem_3 1207 1212 PF02991 0.329
LIG_LIR_Nem_3 1233 1238 PF02991 0.429
LIG_LIR_Nem_3 1256 1261 PF02991 0.345
LIG_LIR_Nem_3 1321 1327 PF02991 0.350
LIG_LIR_Nem_3 1328 1334 PF02991 0.319
LIG_LIR_Nem_3 1335 1341 PF02991 0.303
LIG_LIR_Nem_3 242 248 PF02991 0.450
LIG_LIR_Nem_3 28 34 PF02991 0.546
LIG_LIR_Nem_3 329 334 PF02991 0.309
LIG_LIR_Nem_3 344 349 PF02991 0.319
LIG_LIR_Nem_3 391 395 PF02991 0.368
LIG_LIR_Nem_3 484 489 PF02991 0.273
LIG_LIR_Nem_3 553 558 PF02991 0.418
LIG_LIR_Nem_3 597 602 PF02991 0.351
LIG_LIR_Nem_3 642 647 PF02991 0.381
LIG_LIR_Nem_3 694 698 PF02991 0.303
LIG_LIR_Nem_3 700 704 PF02991 0.303
LIG_LIR_Nem_3 747 752 PF02991 0.319
LIG_LIR_Nem_3 754 758 PF02991 0.329
LIG_LIR_Nem_3 852 857 PF02991 0.303
LIG_LIR_Nem_3 860 864 PF02991 0.303
LIG_LIR_Nem_3 941 947 PF02991 0.403
LIG_LIR_Nem_3 983 987 PF02991 0.295
LIG_LYPXL_S_1 1111 1115 PF13949 0.303
LIG_LYPXL_S_1 758 762 PF13949 0.303
LIG_LYPXL_yS_3 1112 1115 PF13949 0.303
LIG_LYPXL_yS_3 355 358 PF13949 0.450
LIG_LYPXL_yS_3 759 762 PF13949 0.303
LIG_MYND_1 889 893 PF01753 0.424
LIG_NRBOX 539 545 PF00104 0.388
LIG_Pex14_2 766 770 PF04695 0.424
LIG_PTB_Apo_2 1022 1029 PF02174 0.449
LIG_PTB_Phospho_1 1022 1028 PF10480 0.198
LIG_SH2_CRK 1235 1239 PF00017 0.422
LIG_SH2_CRK 1261 1265 PF00017 0.447
LIG_SH2_CRK 291 295 PF00017 0.424
LIG_SH2_CRK 599 603 PF00017 0.360
LIG_SH2_CRK 604 608 PF00017 0.313
LIG_SH2_CRK 644 648 PF00017 0.421
LIG_SH2_CRK 854 858 PF00017 0.303
LIG_SH2_CRK 955 959 PF00017 0.303
LIG_SH2_NCK_1 1296 1300 PF00017 0.403
LIG_SH2_PTP2 1212 1215 PF00017 0.444
LIG_SH2_PTP2 486 489 PF00017 0.198
LIG_SH2_PTP2 749 752 PF00017 0.319
LIG_SH2_STAP1 644 648 PF00017 0.441
LIG_SH2_STAP1 746 750 PF00017 0.303
LIG_SH2_STAT5 1011 1014 PF00017 0.338
LIG_SH2_STAT5 1028 1031 PF00017 0.248
LIG_SH2_STAT5 1075 1078 PF00017 0.303
LIG_SH2_STAT5 1106 1109 PF00017 0.290
LIG_SH2_STAT5 1212 1215 PF00017 0.409
LIG_SH2_STAT5 1225 1228 PF00017 0.270
LIG_SH2_STAT5 1296 1299 PF00017 0.347
LIG_SH2_STAT5 486 489 PF00017 0.334
LIG_SH2_STAT5 496 499 PF00017 0.327
LIG_SH2_STAT5 695 698 PF00017 0.303
LIG_SH2_STAT5 712 715 PF00017 0.303
LIG_SH2_STAT5 749 752 PF00017 0.305
LIG_SH3_2 1271 1276 PF14604 0.500
LIG_SH3_3 1185 1191 PF00018 0.364
LIG_SH3_3 1265 1271 PF00018 0.347
LIG_SH3_3 1306 1312 PF00018 0.445
LIG_SH3_3 15 21 PF00018 0.684
LIG_SH3_3 225 231 PF00018 0.607
LIG_SH3_3 334 340 PF00018 0.336
LIG_SH3_3 411 417 PF00018 0.278
LIG_SH3_3 425 431 PF00018 0.303
LIG_SH3_3 484 490 PF00018 0.252
LIG_SH3_3 53 59 PF00018 0.637
LIG_SH3_3 628 634 PF00018 0.559
LIG_SH3_3 735 741 PF00018 0.303
LIG_SH3_3 780 786 PF00018 0.326
LIG_SH3_4 76 83 PF00018 0.726
LIG_SUMO_SIM_anti_2 115 120 PF11976 0.398
LIG_SUMO_SIM_anti_2 662 668 PF11976 0.449
LIG_SUMO_SIM_anti_2 747 754 PF11976 0.319
LIG_SUMO_SIM_anti_2 883 889 PF11976 0.323
LIG_SUMO_SIM_par_1 169 177 PF11976 0.508
LIG_SUMO_SIM_par_1 255 260 PF11976 0.520
LIG_SUMO_SIM_par_1 489 494 PF11976 0.388
LIG_SUMO_SIM_par_1 747 754 PF11976 0.303
LIG_TRAF2_1 302 305 PF00917 0.314
LIG_TRAF2_1 333 336 PF00917 0.203
LIG_TYR_ITIM 602 607 PF00017 0.424
LIG_TYR_ITIM 693 698 PF00017 0.303
LIG_TYR_ITSM 1231 1238 PF00017 0.429
LIG_TYR_ITSM 1320 1327 PF00017 0.452
LIG_UBA3_1 266 274 PF00899 0.463
LIG_UBA3_1 377 384 PF00899 0.319
LIG_UBA3_1 838 844 PF00899 0.373
LIG_UBA3_1 947 954 PF00899 0.306
LIG_Vh1_VBS_1 636 654 PF01044 0.416
LIG_WRC_WIRS_1 698 703 PF05994 0.388
MOD_CDK_SPK_2 205 210 PF00069 0.673
MOD_CDK_SPK_2 413 418 PF00069 0.319
MOD_CDK_SPxK_1 705 711 PF00069 0.303
MOD_CK1_1 1156 1162 PF00069 0.393
MOD_CK1_1 191 197 PF00069 0.574
MOD_CK1_1 234 240 PF00069 0.354
MOD_CK1_1 279 285 PF00069 0.393
MOD_CK1_1 403 409 PF00069 0.413
MOD_CK1_1 413 419 PF00069 0.418
MOD_CK1_1 551 557 PF00069 0.423
MOD_CK1_1 630 636 PF00069 0.503
MOD_CK1_1 994 1000 PF00069 0.391
MOD_CK2_1 1197 1203 PF00069 0.460
MOD_CK2_1 1294 1300 PF00069 0.424
MOD_CK2_1 135 141 PF00069 0.576
MOD_CK2_1 144 150 PF00069 0.542
MOD_CK2_1 191 197 PF00069 0.556
MOD_CK2_1 299 305 PF00069 0.355
MOD_CK2_1 30 36 PF00069 0.579
MOD_CK2_1 373 379 PF00069 0.316
MOD_CK2_1 816 822 PF00069 0.301
MOD_Cter_Amidation 726 729 PF01082 0.388
MOD_GlcNHglycan 1107 1110 PF01048 0.277
MOD_GlcNHglycan 1246 1249 PF01048 0.368
MOD_GlcNHglycan 184 187 PF01048 0.641
MOD_GlcNHglycan 3 6 PF01048 0.580
MOD_GlcNHglycan 395 398 PF01048 0.434
MOD_GlcNHglycan 400 403 PF01048 0.411
MOD_GlcNHglycan 49 52 PF01048 0.658
MOD_GlcNHglycan 59 62 PF01048 0.494
MOD_GlcNHglycan 799 802 PF01048 0.426
MOD_GSK3_1 1033 1040 PF00069 0.312
MOD_GSK3_1 1156 1163 PF00069 0.409
MOD_GSK3_1 1197 1204 PF00069 0.473
MOD_GSK3_1 1213 1220 PF00069 0.358
MOD_GSK3_1 191 198 PF00069 0.563
MOD_GSK3_1 275 282 PF00069 0.551
MOD_GSK3_1 406 413 PF00069 0.275
MOD_GSK3_1 550 557 PF00069 0.450
MOD_GSK3_1 588 595 PF00069 0.359
MOD_GSK3_1 626 633 PF00069 0.557
MOD_GSK3_1 655 662 PF00069 0.400
MOD_GSK3_1 667 674 PF00069 0.266
MOD_GSK3_1 754 761 PF00069 0.374
MOD_GSK3_1 8 15 PF00069 0.683
MOD_GSK3_1 812 819 PF00069 0.352
MOD_GSK3_1 82 89 PF00069 0.609
MOD_GSK3_1 985 992 PF00069 0.259
MOD_N-GLC_1 776 781 PF02516 0.334
MOD_N-GLC_2 1025 1027 PF02516 0.198
MOD_N-GLC_2 495 497 PF02516 0.198
MOD_N-GLC_2 767 769 PF02516 0.292
MOD_NEK2_1 1 6 PF00069 0.425
MOD_NEK2_1 1033 1038 PF00069 0.313
MOD_NEK2_1 1155 1160 PF00069 0.522
MOD_NEK2_1 1230 1235 PF00069 0.359
MOD_NEK2_1 290 295 PF00069 0.396
MOD_NEK2_1 371 376 PF00069 0.338
MOD_NEK2_1 393 398 PF00069 0.434
MOD_NEK2_1 453 458 PF00069 0.424
MOD_NEK2_1 550 555 PF00069 0.450
MOD_NEK2_1 569 574 PF00069 0.136
MOD_NEK2_1 636 641 PF00069 0.445
MOD_NEK2_1 697 702 PF00069 0.366
MOD_NEK2_1 816 821 PF00069 0.283
MOD_NEK2_1 846 851 PF00069 0.303
MOD_NEK2_1 859 864 PF00069 0.303
MOD_NEK2_1 86 91 PF00069 0.578
MOD_NEK2_1 906 911 PF00069 0.303
MOD_NEK2_2 1319 1324 PF00069 0.358
MOD_NEK2_2 681 686 PF00069 0.319
MOD_OFUCOSY 1229 1234 PF10250 0.457
MOD_PIKK_1 1201 1207 PF00454 0.352
MOD_PIKK_1 1228 1234 PF00454 0.326
MOD_PIKK_1 1253 1259 PF00454 0.405
MOD_PIKK_1 23 29 PF00454 0.707
MOD_PKA_1 671 677 PF00069 0.343
MOD_PKA_1 989 995 PF00069 0.333
MOD_PKA_2 1081 1087 PF00069 0.409
MOD_PKA_2 12 18 PF00069 0.718
MOD_PKA_2 1217 1223 PF00069 0.467
MOD_PKA_2 144 150 PF00069 0.500
MOD_PKA_2 276 282 PF00069 0.539
MOD_PKA_2 393 399 PF00069 0.388
MOD_PKA_2 667 673 PF00069 0.362
MOD_PKA_2 989 995 PF00069 0.282
MOD_Plk_1 114 120 PF00069 0.546
MOD_Plk_1 174 180 PF00069 0.586
MOD_Plk_1 341 347 PF00069 0.388
MOD_Plk_1 410 416 PF00069 0.424
MOD_Plk_1 465 471 PF00069 0.432
MOD_Plk_1 548 554 PF00069 0.395
MOD_Plk_1 8 14 PF00069 0.686
MOD_Plk_1 859 865 PF00069 0.319
MOD_Plk_2-3 1197 1203 PF00069 0.325
MOD_Plk_2-3 176 182 PF00069 0.435
MOD_Plk_2-3 776 782 PF00069 0.424
MOD_Plk_4 114 120 PF00069 0.393
MOD_Plk_4 1156 1162 PF00069 0.409
MOD_Plk_4 1319 1325 PF00069 0.355
MOD_Plk_4 1333 1339 PF00069 0.324
MOD_Plk_4 166 172 PF00069 0.561
MOD_Plk_4 260 266 PF00069 0.418
MOD_Plk_4 366 372 PF00069 0.396
MOD_Plk_4 373 379 PF00069 0.361
MOD_Plk_4 388 394 PF00069 0.232
MOD_Plk_4 481 487 PF00069 0.246
MOD_Plk_4 539 545 PF00069 0.273
MOD_Plk_4 627 633 PF00069 0.443
MOD_Plk_4 754 760 PF00069 0.303
MOD_Plk_4 812 818 PF00069 0.386
MOD_Plk_4 849 855 PF00069 0.303
MOD_Plk_4 901 907 PF00069 0.303
MOD_Plk_4 991 997 PF00069 0.418
MOD_ProDKin_1 1184 1190 PF00069 0.467
MOD_ProDKin_1 149 155 PF00069 0.514
MOD_ProDKin_1 17 23 PF00069 0.609
MOD_ProDKin_1 191 197 PF00069 0.686
MOD_ProDKin_1 205 211 PF00069 0.666
MOD_ProDKin_1 217 223 PF00069 0.610
MOD_ProDKin_1 413 419 PF00069 0.282
MOD_ProDKin_1 630 636 PF00069 0.544
MOD_ProDKin_1 705 711 PF00069 0.303
MOD_SUMO_for_1 1142 1145 PF00179 0.532
MOD_SUMO_for_1 160 163 PF00179 0.499
MOD_SUMO_for_1 827 830 PF00179 0.303
MOD_SUMO_rev_2 556 566 PF00179 0.360
MOD_SUMO_rev_2 818 826 PF00179 0.303
MOD_SUMO_rev_2 920 927 PF00179 0.369
MOD_SUMO_rev_2 962 969 PF00179 0.323
TRG_DiLeu_BaEn_1 822 827 PF01217 0.338
TRG_DiLeu_BaEn_3 1146 1152 PF01217 0.347
TRG_DiLeu_BaLyEn_6 602 607 PF01217 0.450
TRG_DiLeu_BaLyEn_6 94 99 PF01217 0.612
TRG_ENDOCYTIC_2 1112 1115 PF00928 0.281
TRG_ENDOCYTIC_2 1212 1215 PF00928 0.359
TRG_ENDOCYTIC_2 1235 1238 PF00928 0.429
TRG_ENDOCYTIC_2 1261 1264 PF00928 0.447
TRG_ENDOCYTIC_2 1324 1327 PF00928 0.320
TRG_ENDOCYTIC_2 291 294 PF00928 0.424
TRG_ENDOCYTIC_2 331 334 PF00928 0.319
TRG_ENDOCYTIC_2 355 358 PF00928 0.338
TRG_ENDOCYTIC_2 460 463 PF00928 0.319
TRG_ENDOCYTIC_2 486 489 PF00928 0.198
TRG_ENDOCYTIC_2 547 550 PF00928 0.338
TRG_ENDOCYTIC_2 599 602 PF00928 0.360
TRG_ENDOCYTIC_2 604 607 PF00928 0.313
TRG_ENDOCYTIC_2 644 647 PF00928 0.422
TRG_ENDOCYTIC_2 695 698 PF00928 0.303
TRG_ENDOCYTIC_2 749 752 PF00928 0.303
TRG_ENDOCYTIC_2 759 762 PF00928 0.303
TRG_ENDOCYTIC_2 854 857 PF00928 0.303
TRG_ENDOCYTIC_2 861 864 PF00928 0.303
TRG_ENDOCYTIC_2 933 936 PF00928 0.303
TRG_ENDOCYTIC_2 955 958 PF00928 0.303
TRG_ER_diArg_1 1293 1295 PF00400 0.416
TRG_ER_diArg_1 189 192 PF00400 0.709
TRG_ER_diArg_1 285 288 PF00400 0.424
TRG_ER_diArg_1 323 325 PF00400 0.319
TRG_ER_diArg_1 505 507 PF00400 0.388
TRG_ER_diArg_1 544 546 PF00400 0.420
TRG_ER_diArg_1 980 982 PF00400 0.301
TRG_NES_CRM1_1 1120 1132 PF08389 0.429
TRG_NES_CRM1_1 1321 1335 PF08389 0.440
TRG_NES_CRM1_1 84 96 PF08389 0.680
TRG_NES_CRM1_1 914 924 PF08389 0.424
TRG_NLS_Bipartite_1 717 733 PF00514 0.342
TRG_NLS_MonoCore_2 950 955 PF00514 0.303
TRG_NLS_MonoExtC_3 383 388 PF00514 0.388
TRG_NLS_MonoExtC_3 65 70 PF00514 0.524
TRG_NLS_MonoExtC_3 727 732 PF00514 0.319
TRG_NLS_MonoExtC_3 99 105 PF00514 0.606
TRG_NLS_MonoExtN_4 384 389 PF00514 0.385
TRG_NLS_MonoExtN_4 63 70 PF00514 0.528
TRG_NLS_MonoExtN_4 728 733 PF00514 0.319
TRG_NLS_MonoExtN_4 951 956 PF00514 0.303
TRG_NLS_MonoExtN_4 97 104 PF00514 0.582
TRG_Pf-PMV_PEXEL_1 1164 1168 PF00026 0.358
TRG_Pf-PMV_PEXEL_1 1262 1266 PF00026 0.343
TRG_Pf-PMV_PEXEL_1 1287 1292 PF00026 0.339
TRG_Pf-PMV_PEXEL_1 162 166 PF00026 0.343
TRG_Pf-PMV_PEXEL_1 32 36 PF00026 0.612
TRG_Pf-PMV_PEXEL_1 470 474 PF00026 0.382
TRG_Pf-PMV_PEXEL_1 512 516 PF00026 0.396
TRG_Pf-PMV_PEXEL_1 641 645 PF00026 0.473
TRG_Pf-PMV_PEXEL_1 919 924 PF00026 0.315
TRG_Pf-PMV_PEXEL_1 998 1003 PF00026 0.338

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I597 Leptomonas seymouri 81% 100%
A0A0S4IUC6 Bodo saltans 48% 95%
A0A1X0P042 Trypanosomatidae 61% 100%
A0A3R7MDF7 Trypanosoma rangeli 58% 100%
A0A3S5H6Z2 Leishmania donovani 89% 100%
A4HLN0 Leishmania braziliensis 25% 100%
A4HX52 Leishmania infantum 89% 100%
C9ZVT9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 58% 100%
E9AQW7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
O00874 Leishmania donovani 89% 100%
O48653 Oryza sativa subsp. japonica 37% 87%
O89042 Rattus norvegicus 38% 92%
P09884 Homo sapiens 37% 92%
P13382 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 35% 91%
P26019 Drosophila melanogaster 33% 90%
P27727 Trypanosoma brucei brucei 58% 100%
P28040 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 33% 95%
P30315 Plasmodium falciparum (isolate K1 / Thailand) 25% 100%
P33609 Mus musculus 37% 92%
Q27152 Oxytricha trifallax 34% 89%
Q4QEL1 Leishmania major 89% 100%
Q54SV8 Dictyostelium discoideum 33% 89%
Q94636 Sterkiella nova 35% 90%
Q9DE46 Xenopus laevis 38% 92%
Q9FHA3 Arabidopsis thaliana 36% 88%
V5B2M9 Trypanosoma cruzi 60% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS