BEACH-type PH domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H8T1_LEIBR

TriTrypDb:

LbrM.16.1580

Length:

1145

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0031298	replication fork protection complex	3	1
GO:0032991	protein-containing complex	1	1
GO:0140513	nuclear protein-containing complex	2	1

Expansion

Sequence features

A4H8T1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H8T1

Function

Biological processes
Term	Name	Level	Count
GO:0000075	cell cycle checkpoint signaling	4	1
GO:0000076	DNA replication checkpoint signaling	6	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006259	DNA metabolic process	4	1
GO:0006275	regulation of DNA replication	6	1
GO:0006281	DNA repair	5	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0007165	signal transduction	2	1
GO:0008152	metabolic process	1	1
GO:0008156	negative regulation of DNA replication	7	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0009987	cellular process	1	1
GO:0010564	regulation of cell cycle process	5	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0010948	negative regulation of cell cycle process	6	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031324	negative regulation of cellular metabolic process	5	1
GO:0031570	DNA integrity checkpoint signaling	5	1
GO:0033554	cellular response to stress	3	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0035556	intracellular signal transduction	3	1
GO:0043111	replication fork arrest	6	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0045005	DNA-templated DNA replication maintenance of fidelity	5	1
GO:0045786	negative regulation of cell cycle	5	1
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	6	1
GO:0046483	heterocycle metabolic process	3	1
GO:0048478	obsolete replication fork protection	6	1
GO:0048519	negative regulation of biological process	3	1
GO:0048523	negative regulation of cellular process	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0050896	response to stimulus	1	1
GO:0051052	regulation of DNA metabolic process	5	1
GO:0051053	negative regulation of DNA metabolic process	6	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051172	negative regulation of nitrogen compound metabolic process	5	1
GO:0051716	cellular response to stimulus	2	1
GO:0051726	regulation of cell cycle	4	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0071704	organic substance metabolic process	2	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0090304	nucleic acid metabolic process	4	1
GO:0090329	regulation of DNA-templated DNA replication	7	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1901987	regulation of cell cycle phase transition	6	1
GO:1901988	negative regulation of cell cycle phase transition	7	1
GO:2000104	negative regulation of DNA-templated DNA replication	8	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	1
GO:0003677	DNA binding	4	1
GO:0005488	binding	1	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1031	1035	PF00656	0.711
CLV_C14_Caspase3-7	795	799	PF00656	0.554
CLV_NRD_NRD_1	1026	1028	PF00675	0.620
CLV_NRD_NRD_1	1075	1077	PF00675	0.751
CLV_NRD_NRD_1	1088	1090	PF00675	0.594
CLV_NRD_NRD_1	427	429	PF00675	0.613
CLV_NRD_NRD_1	440	442	PF00675	0.452
CLV_NRD_NRD_1	669	671	PF00675	0.341
CLV_NRD_NRD_1	757	759	PF00675	0.628
CLV_NRD_NRD_1	773	775	PF00675	0.567
CLV_PCSK_FUR_1	1024	1028	PF00082	0.609
CLV_PCSK_FUR_1	1086	1090	PF00082	0.534
CLV_PCSK_KEX2_1	1001	1003	PF00082	0.642
CLV_PCSK_KEX2_1	1026	1028	PF00082	0.603
CLV_PCSK_KEX2_1	1068	1070	PF00082	0.697
CLV_PCSK_KEX2_1	1074	1076	PF00082	0.750
CLV_PCSK_KEX2_1	1085	1087	PF00082	0.779
CLV_PCSK_KEX2_1	1088	1090	PF00082	0.519
CLV_PCSK_KEX2_1	176	178	PF00082	0.381
CLV_PCSK_KEX2_1	427	429	PF00082	0.628
CLV_PCSK_KEX2_1	442	444	PF00082	0.464
CLV_PCSK_KEX2_1	699	701	PF00082	0.568
CLV_PCSK_KEX2_1	7	9	PF00082	0.445
CLV_PCSK_KEX2_1	757	759	PF00082	0.538
CLV_PCSK_PC1ET2_1	1001	1003	PF00082	0.642
CLV_PCSK_PC1ET2_1	1068	1070	PF00082	0.697
CLV_PCSK_PC1ET2_1	1074	1076	PF00082	0.750
CLV_PCSK_PC1ET2_1	1085	1087	PF00082	0.779
CLV_PCSK_PC1ET2_1	176	178	PF00082	0.381
CLV_PCSK_PC1ET2_1	442	444	PF00082	0.523
CLV_PCSK_PC1ET2_1	699	701	PF00082	0.603
CLV_PCSK_PC1ET2_1	7	9	PF00082	0.445
CLV_PCSK_PC7_1	1071	1077	PF00082	0.620
CLV_PCSK_SKI1_1	147	151	PF00082	0.425
CLV_PCSK_SKI1_1	445	449	PF00082	0.503
CLV_PCSK_SKI1_1	544	548	PF00082	0.490
CLV_PCSK_SKI1_1	592	596	PF00082	0.312
CLV_PCSK_SKI1_1	653	657	PF00082	0.390
CLV_PCSK_SKI1_1	8	12	PF00082	0.390
CLV_PCSK_SKI1_1	896	900	PF00082	0.382
CLV_PCSK_SKI1_1	963	967	PF00082	0.443
DEG_APCC_DBOX_1	543	551	PF00400	0.419
DEG_APCC_DBOX_1	7	15	PF00400	0.420
DEG_APCC_DBOX_1	821	829	PF00400	0.677
DEG_Nend_Nbox_1	1	3	PF02207	0.378
DEG_SPOP_SBC_1	250	254	PF00917	0.448
DOC_AGCK_PIF_1	675	680	PF00069	0.414
DOC_CYCLIN_RxL_1	960	970	PF00134	0.463
DOC_CYCLIN_yCln2_LP_2	105	111	PF00134	0.428
DOC_MAPK_gen_1	181	190	PF00069	0.409
DOC_MAPK_gen_1	500	510	PF00069	0.392
DOC_MAPK_gen_1	598	608	PF00069	0.413
DOC_MAPK_gen_1	7	14	PF00069	0.420
DOC_MAPK_MEF2A_6	104	111	PF00069	0.381
DOC_MAPK_MEF2A_6	127	136	PF00069	0.331
DOC_MAPK_MEF2A_6	184	192	PF00069	0.335
DOC_MAPK_MEF2A_6	217	225	PF00069	0.329
DOC_MAPK_MEF2A_6	601	610	PF00069	0.448
DOC_MAPK_MEF2A_6	648	656	PF00069	0.352
DOC_MAPK_MEF2A_6	7	14	PF00069	0.420
DOC_MAPK_NFAT4_5	7	15	PF00069	0.423
DOC_MAPK_RevD_3	163	177	PF00069	0.338
DOC_PP1_RVXF_1	651	657	PF00149	0.398
DOC_PP2B_LxvP_1	105	108	PF13499	0.423
DOC_PP2B_LxvP_1	134	137	PF13499	0.388
DOC_PP2B_LxvP_1	460	463	PF13499	0.324
DOC_PP4_FxxP_1	920	923	PF00568	0.383
DOC_USP7_MATH_1	336	340	PF00917	0.436
DOC_USP7_MATH_1	396	400	PF00917	0.558
DOC_USP7_MATH_1	640	644	PF00917	0.361
DOC_USP7_MATH_1	661	665	PF00917	0.366
DOC_USP7_MATH_2	938	944	PF00917	0.498
DOC_USP7_UBL2_3	688	692	PF12436	0.455
DOC_USP7_UBL2_3	699	703	PF12436	0.511
DOC_WW_Pin1_4	1014	1019	PF00397	0.614
DOC_WW_Pin1_4	1041	1046	PF00397	0.527
DOC_WW_Pin1_4	452	457	PF00397	0.532
DOC_WW_Pin1_4	520	525	PF00397	0.539
DOC_WW_Pin1_4	842	847	PF00397	0.496
LIG_14-3-3_CanoR_1	138	145	PF00244	0.447
LIG_14-3-3_CanoR_1	365	371	PF00244	0.632
LIG_14-3-3_CanoR_1	793	798	PF00244	0.614
LIG_14-3-3_CanoR_1	807	815	PF00244	0.582
LIG_14-3-3_CanoR_1	822	826	PF00244	0.564
LIG_14-3-3_CanoR_1	932	937	PF00244	0.628
LIG_Actin_WH2_2	533	550	PF00022	0.303
LIG_APCC_ABBA_1	644	649	PF00400	0.264
LIG_BRCT_BRCA1_1	476	480	PF00533	0.440
LIG_BRCT_BRCA1_1	836	840	PF00533	0.499
LIG_BRCT_BRCA1_1	883	887	PF00533	0.495
LIG_Clathr_ClatBox_1	11	15	PF01394	0.417
LIG_deltaCOP1_diTrp_1	323	329	PF00928	0.376
LIG_deltaCOP1_diTrp_1	384	388	PF00928	0.578
LIG_EH1_1	218	226	PF00400	0.446
LIG_EH1_1	871	879	PF00400	0.442
LIG_eIF4E_1	612	618	PF01652	0.407
LIG_eIF4E_1	691	697	PF01652	0.523
LIG_FHA_1	1109	1115	PF00498	0.574
LIG_FHA_1	1129	1135	PF00498	0.584
LIG_FHA_1	1139	1145	PF00498	0.520
LIG_FHA_1	139	145	PF00498	0.369
LIG_FHA_1	177	183	PF00498	0.533
LIG_FHA_1	196	202	PF00498	0.330
LIG_FHA_1	206	212	PF00498	0.487
LIG_FHA_1	264	270	PF00498	0.734
LIG_FHA_1	410	416	PF00498	0.467
LIG_FHA_1	47	53	PF00498	0.431
LIG_FHA_1	520	526	PF00498	0.544
LIG_FHA_1	605	611	PF00498	0.264
LIG_FHA_1	677	683	PF00498	0.415
LIG_FHA_1	713	719	PF00498	0.594
LIG_FHA_1	960	966	PF00498	0.488
LIG_FHA_2	793	799	PF00498	0.593
LIG_FHA_2	806	812	PF00498	0.543
LIG_FHA_2	82	88	PF00498	0.474
LIG_FHA_2	972	978	PF00498	0.525
LIG_GBD_Chelix_1	609	617	PF00786	0.283
LIG_IRF3_LxIS_1	14	20	PF10401	0.421
LIG_KLC1_Yacidic_2	972	977	PF13176	0.520
LIG_LIR_Apic_2	339	345	PF02991	0.397
LIG_LIR_Apic_2	919	923	PF02991	0.402
LIG_LIR_Gen_1	160	171	PF02991	0.330
LIG_LIR_Gen_1	473	483	PF02991	0.354
LIG_LIR_Gen_1	527	537	PF02991	0.407
LIG_LIR_Gen_1	563	569	PF02991	0.620
LIG_LIR_Gen_1	585	595	PF02991	0.364
LIG_LIR_Gen_1	679	686	PF02991	0.421
LIG_LIR_Gen_1	837	846	PF02991	0.497
LIG_LIR_Gen_1	850	861	PF02991	0.473
LIG_LIR_Gen_1	92	101	PF02991	0.355
LIG_LIR_Gen_1	970	981	PF02991	0.468
LIG_LIR_Gen_1	986	993	PF02991	0.545
LIG_LIR_LC3C_4	103	107	PF02991	0.436
LIG_LIR_LC3C_4	1139	1144	PF02991	0.496
LIG_LIR_LC3C_4	222	227	PF02991	0.383
LIG_LIR_Nem_3	159	165	PF02991	0.326
LIG_LIR_Nem_3	383	389	PF02991	0.527
LIG_LIR_Nem_3	419	424	PF02991	0.583
LIG_LIR_Nem_3	473	478	PF02991	0.338
LIG_LIR_Nem_3	487	491	PF02991	0.320
LIG_LIR_Nem_3	527	533	PF02991	0.483
LIG_LIR_Nem_3	585	591	PF02991	0.365
LIG_LIR_Nem_3	643	647	PF02991	0.287
LIG_LIR_Nem_3	679	683	PF02991	0.416
LIG_LIR_Nem_3	837	843	PF02991	0.441
LIG_LIR_Nem_3	850	856	PF02991	0.399
LIG_LIR_Nem_3	883	889	PF02991	0.489
LIG_LIR_Nem_3	92	96	PF02991	0.246
LIG_LIR_Nem_3	951	955	PF02991	0.443
LIG_LIR_Nem_3	970	976	PF02991	0.376
LIG_MAD2	915	923	PF02301	0.488
LIG_MLH1_MIPbox_1	836	840	PF16413	0.499
LIG_MLH1_MIPbox_1	883	887	PF16413	0.423
LIG_NRBOX	124	130	PF00104	0.324
LIG_NRBOX	366	372	PF00104	0.617
LIG_NRBOX	619	625	PF00104	0.434
LIG_Pex14_2	564	568	PF04695	0.419
LIG_Pex14_2	887	891	PF04695	0.373
LIG_Pex14_2	921	925	PF04695	0.467
LIG_PTB_Apo_2	226	233	PF02174	0.341
LIG_PTB_Apo_2	885	892	PF02174	0.390
LIG_PTB_Apo_2	919	926	PF02174	0.420
LIG_PTB_Phospho_1	226	232	PF10480	0.333
LIG_REV1ctd_RIR_1	837	845	PF16727	0.435
LIG_RPA_C_Fungi	660	672	PF08784	0.285
LIG_SH2_CRK	232	236	PF00017	0.450
LIG_SH2_CRK	451	455	PF00017	0.400
LIG_SH2_CRK	530	534	PF00017	0.458
LIG_SH2_CRK	539	543	PF00017	0.407
LIG_SH2_CRK	853	857	PF00017	0.475
LIG_SH2_GRB2like	74	77	PF00017	0.674
LIG_SH2_NCK_1	64	68	PF00017	0.492
LIG_SH2_PTP2	549	552	PF00017	0.361
LIG_SH2_SRC	64	67	PF00017	0.465
LIG_SH2_STAP1	662	666	PF00017	0.455
LIG_SH2_STAT5	199	202	PF00017	0.442
LIG_SH2_STAT5	549	552	PF00017	0.377
LIG_SH2_STAT5	612	615	PF00017	0.288
LIG_SH2_STAT5	952	955	PF00017	0.557
LIG_SH2_STAT5	973	976	PF00017	0.581
LIG_SH2_STAT5	987	990	PF00017	0.647
LIG_SH3_3	1117	1123	PF00018	0.574
LIG_SH3_3	1127	1133	PF00018	0.628
LIG_SH3_3	563	569	PF00018	0.462
LIG_SUMO_SIM_anti_2	185	191	PF11976	0.323
LIG_SUMO_SIM_anti_2	222	228	PF11976	0.438
LIG_SUMO_SIM_anti_2	481	487	PF11976	0.350
LIG_SUMO_SIM_anti_2	604	610	PF11976	0.383
LIG_SUMO_SIM_par_1	10	15	PF11976	0.410
LIG_SUMO_SIM_par_1	1118	1124	PF11976	0.499
LIG_SUMO_SIM_par_1	1139	1145	PF11976	0.564
LIG_SUMO_SIM_par_1	185	191	PF11976	0.347
LIG_SUMO_SIM_par_1	192	198	PF11976	0.329
LIG_SUMO_SIM_par_1	481	487	PF11976	0.410
LIG_SUMO_SIM_par_1	576	582	PF11976	0.337
LIG_TRAF2_1	1137	1140	PF00917	0.495
LIG_TRAF2_1	345	348	PF00917	0.477
LIG_TRAF2_1	708	711	PF00917	0.538
LIG_TYR_ITIM	537	542	PF00017	0.331
LIG_TYR_ITIM	547	552	PF00017	0.351
LIG_TYR_ITIM	851	856	PF00017	0.461
LIG_TYR_ITIM	971	976	PF00017	0.525
LIG_UBA3_1	121	127	PF00899	0.329
LIG_UBA3_1	149	154	PF00899	0.404
LIG_WRC_WIRS_1	475	480	PF05994	0.433
LIG_WRC_WIRS_1	485	490	PF05994	0.373
LIG_WRC_WIRS_1	591	596	PF05994	0.431
LIG_WRC_WIRS_1	641	646	PF05994	0.246
LIG_WRC_WIRS_1	677	682	PF05994	0.414
MOD_CDK_SPK_2	842	847	PF00069	0.496
MOD_CDK_SPxxK_3	1014	1021	PF00069	0.609
MOD_CK1_1	1017	1023	PF00069	0.721
MOD_CK1_1	1058	1064	PF00069	0.506
MOD_CK1_1	1113	1119	PF00069	0.505
MOD_CK1_1	26	32	PF00069	0.406
MOD_CK1_1	294	300	PF00069	0.568
MOD_CK1_1	358	364	PF00069	0.655
MOD_CK1_1	369	375	PF00069	0.494
MOD_CK1_1	407	413	PF00069	0.681
MOD_CK1_1	484	490	PF00069	0.435
MOD_CK1_1	574	580	PF00069	0.252
MOD_CK1_1	660	666	PF00069	0.452
MOD_CK1_1	698	704	PF00069	0.632
MOD_CK1_1	712	718	PF00069	0.718
MOD_CK1_1	726	732	PF00069	0.684
MOD_CK1_1	796	802	PF00069	0.522
MOD_CK1_1	805	811	PF00069	0.630
MOD_CK1_1	816	822	PF00069	0.600
MOD_CK1_1	826	832	PF00069	0.551
MOD_CK2_1	1106	1112	PF00069	0.683
MOD_CK2_1	1134	1140	PF00069	0.557
MOD_CK2_1	137	143	PF00069	0.437
MOD_CK2_1	251	257	PF00069	0.561
MOD_CK2_1	26	32	PF00069	0.442
MOD_CK2_1	315	321	PF00069	0.537
MOD_CK2_1	54	60	PF00069	0.452
MOD_CK2_1	705	711	PF00069	0.530
MOD_CK2_1	805	811	PF00069	0.576
MOD_CK2_1	827	833	PF00069	0.544
MOD_CK2_1	86	92	PF00069	0.586
MOD_CK2_1	971	977	PF00069	0.493
MOD_GlcNHglycan	1030	1033	PF01048	0.788
MOD_GlcNHglycan	1060	1063	PF01048	0.506
MOD_GlcNHglycan	253	256	PF01048	0.506
MOD_GlcNHglycan	360	363	PF01048	0.503
MOD_GlcNHglycan	407	410	PF01048	0.637
MOD_GlcNHglycan	514	517	PF01048	0.428
MOD_GlcNHglycan	627	631	PF01048	0.296
MOD_GlcNHglycan	659	662	PF01048	0.294
MOD_GlcNHglycan	710	714	PF01048	0.799
MOD_GlcNHglycan	728	731	PF01048	0.681
MOD_GlcNHglycan	777	780	PF01048	0.700
MOD_GlcNHglycan	836	839	PF01048	0.601
MOD_GlcNHglycan	942	945	PF01048	0.615
MOD_GlcNHglycan	946	949	PF01048	0.558
MOD_GSK3_1	1051	1058	PF00069	0.533
MOD_GSK3_1	1106	1113	PF00069	0.643
MOD_GSK3_1	1134	1141	PF00069	0.499
MOD_GSK3_1	24	31	PF00069	0.430
MOD_GSK3_1	291	298	PF00069	0.565
MOD_GSK3_1	315	322	PF00069	0.484
MOD_GSK3_1	332	339	PF00069	0.209
MOD_GSK3_1	365	372	PF00069	0.618
MOD_GSK3_1	404	411	PF00069	0.714
MOD_GSK3_1	419	426	PF00069	0.655
MOD_GSK3_1	466	473	PF00069	0.562
MOD_GSK3_1	520	527	PF00069	0.462
MOD_GSK3_1	573	580	PF00069	0.267
MOD_GSK3_1	586	593	PF00069	0.295
MOD_GSK3_1	657	664	PF00069	0.341
MOD_GSK3_1	687	694	PF00069	0.451
MOD_GSK3_1	705	712	PF00069	0.575
MOD_GSK3_1	787	794	PF00069	0.605
MOD_GSK3_1	801	808	PF00069	0.649
MOD_GSK3_1	813	820	PF00069	0.554
MOD_GSK3_1	823	830	PF00069	0.553
MOD_GSK3_1	847	854	PF00069	0.471
MOD_GSK3_1	940	947	PF00069	0.618
MOD_GSK3_1	955	962	PF00069	0.470
MOD_GSK3_1	967	974	PF00069	0.516
MOD_GSK3_1	988	995	PF00069	0.562
MOD_N-GLC_1	1106	1111	PF02516	0.588
MOD_N-GLC_1	115	120	PF02516	0.389
MOD_N-GLC_1	17	22	PF02516	0.295
MOD_N-GLC_1	230	235	PF02516	0.441
MOD_N-GLC_1	238	243	PF02516	0.505
MOD_N-GLC_1	355	360	PF02516	0.391
MOD_N-GLC_1	471	476	PF02516	0.311
MOD_N-GLC_1	733	738	PF02516	0.594
MOD_N-GLC_1	766	771	PF02516	0.499
MOD_N-GLC_1	847	852	PF02516	0.468
MOD_N-GLC_1	966	971	PF02516	0.489
MOD_N-GLC_2	880	882	PF02516	0.340
MOD_NEK2_1	117	122	PF00069	0.376
MOD_NEK2_1	17	22	PF00069	0.349
MOD_NEK2_1	2	7	PF00069	0.341
MOD_NEK2_1	251	256	PF00069	0.466
MOD_NEK2_1	295	300	PF00069	0.520
MOD_NEK2_1	332	337	PF00069	0.326
MOD_NEK2_1	355	360	PF00069	0.405
MOD_NEK2_1	423	428	PF00069	0.468
MOD_NEK2_1	450	455	PF00069	0.393
MOD_NEK2_1	519	524	PF00069	0.377
MOD_NEK2_1	525	530	PF00069	0.310
MOD_NEK2_1	586	591	PF00069	0.409
MOD_NEK2_1	678	683	PF00069	0.321
MOD_NEK2_1	695	700	PF00069	0.513
MOD_NEK2_1	787	792	PF00069	0.742
MOD_NEK2_1	851	856	PF00069	0.369
MOD_NEK2_1	873	878	PF00069	0.326
MOD_NEK2_1	955	960	PF00069	0.471
MOD_NEK2_1	966	971	PF00069	0.482
MOD_NEK2_1	985	990	PF00069	0.495
MOD_NEK2_2	416	421	PF00069	0.585
MOD_PIKK_1	1033	1039	PF00454	0.653
MOD_PK_1	813	819	PF00069	0.697
MOD_PKA_1	1026	1032	PF00069	0.546
MOD_PKA_1	176	182	PF00069	0.417
MOD_PKA_2	1025	1031	PF00069	0.656
MOD_PKA_2	1070	1076	PF00069	0.628
MOD_PKA_2	137	143	PF00069	0.437
MOD_PKA_2	176	182	PF00069	0.417
MOD_PKA_2	271	277	PF00069	0.488
MOD_PKA_2	404	410	PF00069	0.551
MOD_PKA_2	499	505	PF00069	0.456
MOD_PKA_2	792	798	PF00069	0.722
MOD_PKA_2	802	808	PF00069	0.712
MOD_PKA_2	821	827	PF00069	0.674
MOD_PKA_2	959	965	PF00069	0.484
MOD_PKB_1	1024	1032	PF00069	0.525
MOD_Plk_1	1106	1112	PF00069	0.509
MOD_Plk_1	1138	1144	PF00069	0.496
MOD_Plk_1	17	23	PF00069	0.303
MOD_Plk_1	230	236	PF00069	0.485
MOD_Plk_1	278	284	PF00069	0.495
MOD_Plk_1	291	297	PF00069	0.579
MOD_Plk_1	46	52	PF00069	0.505
MOD_Plk_1	471	477	PF00069	0.327
MOD_Plk_1	525	531	PF00069	0.320
MOD_Plk_1	604	610	PF00069	0.378
MOD_Plk_1	820	826	PF00069	0.656
MOD_Plk_1	847	853	PF00069	0.439
MOD_Plk_1	91	97	PF00069	0.333
MOD_Plk_1	955	961	PF00069	0.438
MOD_Plk_1	966	972	PF00069	0.448
MOD_Plk_2-3	65	71	PF00069	0.472
MOD_Plk_2-3	733	739	PF00069	0.700
MOD_Plk_4	1051	1057	PF00069	0.503
MOD_Plk_4	1138	1144	PF00069	0.560
MOD_Plk_4	117	123	PF00069	0.364
MOD_Plk_4	192	198	PF00069	0.335
MOD_Plk_4	207	213	PF00069	0.394
MOD_Plk_4	315	321	PF00069	0.340
MOD_Plk_4	336	342	PF00069	0.434
MOD_Plk_4	350	356	PF00069	0.508
MOD_Plk_4	366	372	PF00069	0.604
MOD_Plk_4	416	422	PF00069	0.559
MOD_Plk_4	471	477	PF00069	0.316
MOD_Plk_4	481	487	PF00069	0.329
MOD_Plk_4	525	531	PF00069	0.327
MOD_Plk_4	560	566	PF00069	0.504
MOD_Plk_4	574	580	PF00069	0.252
MOD_Plk_4	604	610	PF00069	0.287
MOD_Plk_4	691	697	PF00069	0.453
MOD_Plk_4	868	874	PF00069	0.423
MOD_Plk_4	881	887	PF00069	0.370
MOD_Plk_4	932	938	PF00069	0.641
MOD_Plk_4	948	954	PF00069	0.371
MOD_Plk_4	971	977	PF00069	0.498
MOD_ProDKin_1	1014	1020	PF00069	0.617
MOD_ProDKin_1	1041	1047	PF00069	0.527
MOD_ProDKin_1	452	458	PF00069	0.520
MOD_ProDKin_1	520	526	PF00069	0.538
MOD_ProDKin_1	842	848	PF00069	0.490
MOD_SUMO_for_1	1000	1003	PF00179	0.723
MOD_SUMO_for_1	557	560	PF00179	0.467
MOD_SUMO_for_1	900	903	PF00179	0.318
MOD_SUMO_rev_2	372	382	PF00179	0.411
MOD_SUMO_rev_2	499	508	PF00179	0.510
MOD_SUMO_rev_2	593	600	PF00179	0.417
MOD_SUMO_rev_2	754	763	PF00179	0.736
MOD_SUMO_rev_2	769	777	PF00179	0.718
MOD_SUMO_rev_2	972	981	PF00179	0.462
TRG_DiLeu_BaEn_1	1115	1120	PF01217	0.505
TRG_DiLeu_BaEn_1	161	166	PF01217	0.340
TRG_DiLeu_BaEn_2	559	565	PF01217	0.524
TRG_DiLeu_BaEn_4	347	353	PF01217	0.476
TRG_DiLeu_BaLyEn_6	105	110	PF01217	0.329
TRG_DiLeu_BaLyEn_6	40	45	PF01217	0.399
TRG_DiLeu_BaLyEn_6	783	788	PF01217	0.491
TRG_ENDOCYTIC_2	232	235	PF00928	0.438
TRG_ENDOCYTIC_2	451	454	PF00928	0.553
TRG_ENDOCYTIC_2	530	533	PF00928	0.365
TRG_ENDOCYTIC_2	539	542	PF00928	0.266
TRG_ENDOCYTIC_2	549	552	PF00928	0.220
TRG_ENDOCYTIC_2	64	67	PF00928	0.407
TRG_ENDOCYTIC_2	853	856	PF00928	0.467
TRG_ENDOCYTIC_2	918	921	PF00928	0.379
TRG_ENDOCYTIC_2	952	955	PF00928	0.557
TRG_ENDOCYTIC_2	973	976	PF00928	0.457
TRG_ENDOCYTIC_2	987	990	PF00928	0.553
TRG_ER_diArg_1	1024	1027	PF00400	0.627
TRG_ER_diArg_1	1075	1078	PF00400	0.658
TRG_ER_diArg_1	1086	1089	PF00400	0.609
TRG_ER_diArg_1	40	43	PF00400	0.362
TRG_ER_diArg_1	440	443	PF00400	0.461
TRG_ER_diArg_1	48	51	PF00400	0.393
TRG_ER_diArg_1	600	603	PF00400	0.356
TRG_ER_diArg_1	757	759	PF00400	0.538
TRG_NLS_Bipartite_1	1068	1089	PF00514	0.717
TRG_NLS_Bipartite_1	427	446	PF00514	0.587
TRG_NLS_MonoCore_2	1084	1089	PF00514	0.734
TRG_NLS_MonoExtC_3	1073	1078	PF00514	0.732
TRG_NLS_MonoExtC_3	1084	1089	PF00514	0.818
TRG_NLS_MonoExtC_3	440	445	PF00514	0.497
TRG_NLS_MonoExtC_3	698	703	PF00514	0.490
TRG_NLS_MonoExtN_4	1071	1078	PF00514	0.743
TRG_NLS_MonoExtN_4	1084	1089	PF00514	0.834
TRG_NLS_MonoExtN_4	441	446	PF00514	0.499
TRG_NLS_MonoExtN_4	699	706	PF00514	0.589
TRG_Pf-PMV_PEXEL_1	306	310	PF00026	0.531
TRG_Pf-PMV_PEXEL_1	43	47	PF00026	0.370
TRG_Pf-PMV_PEXEL_1	551	555	PF00026	0.445

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PC20	Leptomonas seymouri	64%	100%
A0A3S7WU73	Leishmania donovani	75%	100%
A0A422N424	Trypanosoma rangeli	41%	100%
A4HX50	Leishmania infantum	75%	100%
C9ZVU2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
E9AQW5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%
Q4QEL3	Leishmania major	75%	100%
V5BS96	Trypanosoma cruzi	40%	100%