LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

DNA-directed RNA polymerase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
DNA-directed RNA polymerase
Gene product:
DNA-directed rna polymerase I largest subunit, putative
Species:
Leishmania braziliensis
UniProt:
A4H8R3_LEIBR
TriTrypDb:
LbrM.16.1400 , LBRM2903_160021600
Length:
1814

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0000428 DNA-directed RNA polymerase complex 4 11
GO:0005634 nucleus 5 10
GO:0030880 RNA polymerase complex 3 11
GO:0032991 protein-containing complex 1 11
GO:0043226 organelle 2 10
GO:0043227 membrane-bounded organelle 3 10
GO:0043229 intracellular organelle 3 10
GO:0043231 intracellular membrane-bounded organelle 4 10
GO:0061695 transferase complex, transferring phosphorus-containing groups 4 11
GO:0110165 cellular anatomical entity 1 10
GO:0140535 intracellular protein-containing complex 2 11
GO:1902494 catalytic complex 2 11
GO:1990234 transferase complex 3 11
GO:0005736 RNA polymerase I complex 4 1
GO:0055029 nuclear DNA-directed RNA polymerase complex 3 1
GO:0140513 nuclear protein-containing complex 2 1

Expansion

Sequence features

A4H8R3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 11
GO:0006351 DNA-templated transcription 7 11
GO:0006725 cellular aromatic compound metabolic process 3 11
GO:0006807 nitrogen compound metabolic process 2 11
GO:0008152 metabolic process 1 11
GO:0009058 biosynthetic process 2 11
GO:0009059 macromolecule biosynthetic process 4 11
GO:0009987 cellular process 1 11
GO:0016070 RNA metabolic process 5 11
GO:0018130 heterocycle biosynthetic process 4 11
GO:0019438 aromatic compound biosynthetic process 4 11
GO:0032774 RNA biosynthetic process 5 11
GO:0034641 cellular nitrogen compound metabolic process 3 11
GO:0034654 nucleobase-containing compound biosynthetic process 4 11
GO:0043170 macromolecule metabolic process 3 11
GO:0044237 cellular metabolic process 2 11
GO:0044238 primary metabolic process 2 11
GO:0044249 cellular biosynthetic process 3 11
GO:0044271 cellular nitrogen compound biosynthetic process 4 11
GO:0046483 heterocycle metabolic process 3 11
GO:0071704 organic substance metabolic process 2 11
GO:0090304 nucleic acid metabolic process 4 11
GO:0097659 nucleic acid-templated transcription 6 11
GO:1901360 organic cyclic compound metabolic process 3 11
GO:1901362 organic cyclic compound biosynthetic process 4 11
GO:1901576 organic substance biosynthetic process 3 11
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 11
GO:0003677 DNA binding 4 11
GO:0003824 catalytic activity 1 11
GO:0003899 DNA-directed 5'-3' RNA polymerase activity 6 11
GO:0005488 binding 1 11
GO:0008270 zinc ion binding 6 11
GO:0016740 transferase activity 2 11
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 11
GO:0016779 nucleotidyltransferase activity 4 11
GO:0034062 5'-3' RNA polymerase activity 5 11
GO:0043167 ion binding 2 11
GO:0043169 cation binding 3 11
GO:0046872 metal ion binding 4 11
GO:0046914 transition metal ion binding 5 11
GO:0097159 organic cyclic compound binding 2 11
GO:0097747 RNA polymerase activity 4 11
GO:0140098 catalytic activity, acting on RNA 3 11
GO:0140640 catalytic activity, acting on a nucleic acid 2 11
GO:1901363 heterocyclic compound binding 2 11

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1062 1066 PF00656 0.392
CLV_C14_Caspase3-7 1493 1497 PF00656 0.489
CLV_NRD_NRD_1 1102 1104 PF00675 0.274
CLV_NRD_NRD_1 117 119 PF00675 0.531
CLV_NRD_NRD_1 1220 1222 PF00675 0.279
CLV_NRD_NRD_1 1366 1368 PF00675 0.203
CLV_NRD_NRD_1 1503 1505 PF00675 0.296
CLV_NRD_NRD_1 1642 1644 PF00675 0.256
CLV_NRD_NRD_1 200 202 PF00675 0.476
CLV_NRD_NRD_1 224 226 PF00675 0.456
CLV_NRD_NRD_1 23 25 PF00675 0.468
CLV_NRD_NRD_1 339 341 PF00675 0.484
CLV_NRD_NRD_1 589 591 PF00675 0.192
CLV_NRD_NRD_1 64 66 PF00675 0.444
CLV_NRD_NRD_1 786 788 PF00675 0.225
CLV_NRD_NRD_1 819 821 PF00675 0.247
CLV_NRD_NRD_1 899 901 PF00675 0.340
CLV_NRD_NRD_1 980 982 PF00675 0.220
CLV_PCSK_FUR_1 1199 1203 PF00082 0.221
CLV_PCSK_FUR_1 196 200 PF00082 0.491
CLV_PCSK_FUR_1 981 985 PF00082 0.192
CLV_PCSK_KEX2_1 1130 1132 PF00082 0.221
CLV_PCSK_KEX2_1 117 119 PF00082 0.531
CLV_PCSK_KEX2_1 1201 1203 PF00082 0.203
CLV_PCSK_KEX2_1 1219 1221 PF00082 0.152
CLV_PCSK_KEX2_1 1682 1684 PF00082 0.248
CLV_PCSK_KEX2_1 1714 1716 PF00082 0.245
CLV_PCSK_KEX2_1 1761 1763 PF00082 0.271
CLV_PCSK_KEX2_1 198 200 PF00082 0.453
CLV_PCSK_KEX2_1 223 225 PF00082 0.443
CLV_PCSK_KEX2_1 339 341 PF00082 0.374
CLV_PCSK_KEX2_1 503 505 PF00082 0.192
CLV_PCSK_KEX2_1 552 554 PF00082 0.220
CLV_PCSK_KEX2_1 589 591 PF00082 0.192
CLV_PCSK_KEX2_1 64 66 PF00082 0.444
CLV_PCSK_KEX2_1 899 901 PF00082 0.323
CLV_PCSK_KEX2_1 980 982 PF00082 0.195
CLV_PCSK_KEX2_1 983 985 PF00082 0.188
CLV_PCSK_KEX2_1 999 1001 PF00082 0.159
CLV_PCSK_PC1ET2_1 1130 1132 PF00082 0.207
CLV_PCSK_PC1ET2_1 1201 1203 PF00082 0.218
CLV_PCSK_PC1ET2_1 1682 1684 PF00082 0.248
CLV_PCSK_PC1ET2_1 1714 1716 PF00082 0.245
CLV_PCSK_PC1ET2_1 1761 1763 PF00082 0.294
CLV_PCSK_PC1ET2_1 503 505 PF00082 0.192
CLV_PCSK_PC1ET2_1 552 554 PF00082 0.220
CLV_PCSK_PC1ET2_1 983 985 PF00082 0.201
CLV_PCSK_PC1ET2_1 999 1001 PF00082 0.166
CLV_PCSK_PC7_1 196 202 PF00082 0.577
CLV_PCSK_SKI1_1 1146 1150 PF00082 0.287
CLV_PCSK_SKI1_1 1187 1191 PF00082 0.236
CLV_PCSK_SKI1_1 1270 1274 PF00082 0.192
CLV_PCSK_SKI1_1 1362 1366 PF00082 0.235
CLV_PCSK_SKI1_1 1663 1667 PF00082 0.232
CLV_PCSK_SKI1_1 1677 1681 PF00082 0.220
CLV_PCSK_SKI1_1 1703 1707 PF00082 0.220
CLV_PCSK_SKI1_1 1711 1715 PF00082 0.221
CLV_PCSK_SKI1_1 1761 1765 PF00082 0.333
CLV_PCSK_SKI1_1 267 271 PF00082 0.405
CLV_PCSK_SKI1_1 278 282 PF00082 0.254
CLV_PCSK_SKI1_1 395 399 PF00082 0.243
CLV_PCSK_SKI1_1 40 44 PF00082 0.391
CLV_PCSK_SKI1_1 532 536 PF00082 0.274
CLV_PCSK_SKI1_1 547 551 PF00082 0.192
CLV_PCSK_SKI1_1 609 613 PF00082 0.196
CLV_PCSK_SKI1_1 774 778 PF00082 0.138
CLV_PCSK_SKI1_1 900 904 PF00082 0.467
CLV_PCSK_SKI1_1 980 984 PF00082 0.286
DEG_APCC_DBOX_1 39 47 PF00400 0.249
DEG_APCC_DBOX_1 673 681 PF00400 0.344
DEG_COP1_1 418 427 PF00400 0.359
DEG_SCF_TRCP1_1 1328 1333 PF00400 0.344
DOC_CKS1_1 1450 1455 PF01111 0.487
DOC_CYCLIN_RxL_1 1142 1152 PF00134 0.487
DOC_CYCLIN_RxL_1 1267 1277 PF00134 0.392
DOC_CYCLIN_RxL_1 528 538 PF00134 0.392
DOC_CYCLIN_yCln2_LP_2 403 406 PF00134 0.233
DOC_MAPK_DCC_7 401 409 PF00069 0.243
DOC_MAPK_gen_1 1573 1579 PF00069 0.474
DOC_MAPK_gen_1 24 32 PF00069 0.423
DOC_MAPK_MEF2A_6 1280 1287 PF00069 0.420
DOC_MAPK_MEF2A_6 24 32 PF00069 0.403
DOC_MAPK_MEF2A_6 40 48 PF00069 0.318
DOC_MAPK_MEF2A_6 401 409 PF00069 0.243
DOC_MAPK_RevD_3 11 25 PF00069 0.379
DOC_MAPK_RevD_3 1354 1368 PF00069 0.344
DOC_MAPK_RevD_3 1669 1683 PF00069 0.400
DOC_PP1_RVXF_1 393 399 PF00149 0.266
DOC_PP1_RVXF_1 530 537 PF00149 0.392
DOC_PP1_RVXF_1 640 647 PF00149 0.392
DOC_PP2B_LxvP_1 380 383 PF13499 0.300
DOC_PP2B_LxvP_1 402 405 PF13499 0.230
DOC_PP2B_LxvP_1 582 585 PF13499 0.404
DOC_PP2B_LxvP_1 912 915 PF13499 0.342
DOC_PP2B_PxIxI_1 1563 1569 PF00149 0.344
DOC_PP4_FxxP_1 155 158 PF00568 0.236
DOC_PP4_FxxP_1 1655 1658 PF00568 0.400
DOC_PP4_FxxP_1 265 268 PF00568 0.373
DOC_SPAK_OSR1_1 154 158 PF12202 0.370
DOC_USP7_MATH_1 1066 1070 PF00917 0.487
DOC_USP7_MATH_1 123 127 PF00917 0.557
DOC_USP7_MATH_1 1326 1330 PF00917 0.371
DOC_USP7_MATH_1 1463 1467 PF00917 0.357
DOC_USP7_MATH_1 1498 1502 PF00917 0.489
DOC_USP7_MATH_1 1552 1556 PF00917 0.428
DOC_USP7_MATH_1 252 256 PF00917 0.640
DOC_USP7_MATH_1 280 284 PF00917 0.415
DOC_USP7_MATH_1 449 453 PF00917 0.438
DOC_USP7_MATH_1 508 512 PF00917 0.392
DOC_USP7_MATH_1 958 962 PF00917 0.392
DOC_USP7_UBL2_3 1197 1201 PF12436 0.408
DOC_WW_Pin1_4 1335 1340 PF00397 0.497
DOC_WW_Pin1_4 1449 1454 PF00397 0.487
DOC_WW_Pin1_4 1510 1515 PF00397 0.461
DOC_WW_Pin1_4 1747 1752 PF00397 0.429
DOC_WW_Pin1_4 295 300 PF00397 0.314
DOC_WW_Pin1_4 450 455 PF00397 0.340
DOC_WW_Pin1_4 511 516 PF00397 0.392
DOC_WW_Pin1_4 541 546 PF00397 0.487
DOC_WW_Pin1_4 739 744 PF00397 0.344
LIG_14-3-3_CanoR_1 1000 1005 PF00244 0.414
LIG_14-3-3_CanoR_1 1010 1017 PF00244 0.291
LIG_14-3-3_CanoR_1 1084 1089 PF00244 0.487
LIG_14-3-3_CanoR_1 129 133 PF00244 0.499
LIG_14-3-3_CanoR_1 1309 1317 PF00244 0.487
LIG_14-3-3_CanoR_1 1334 1339 PF00244 0.472
LIG_14-3-3_CanoR_1 1367 1373 PF00244 0.464
LIG_14-3-3_CanoR_1 1626 1630 PF00244 0.344
LIG_14-3-3_CanoR_1 1663 1672 PF00244 0.426
LIG_14-3-3_CanoR_1 1683 1692 PF00244 0.419
LIG_14-3-3_CanoR_1 17 22 PF00244 0.387
LIG_14-3-3_CanoR_1 1715 1719 PF00244 0.413
LIG_14-3-3_CanoR_1 1762 1772 PF00244 0.295
LIG_14-3-3_CanoR_1 300 308 PF00244 0.336
LIG_14-3-3_CanoR_1 340 348 PF00244 0.380
LIG_14-3-3_CanoR_1 349 353 PF00244 0.309
LIG_14-3-3_CanoR_1 410 417 PF00244 0.315
LIG_14-3-3_CanoR_1 430 439 PF00244 0.165
LIG_14-3-3_CanoR_1 532 537 PF00244 0.392
LIG_14-3-3_CanoR_1 874 879 PF00244 0.487
LIG_14-3-3_CanoR_1 899 907 PF00244 0.477
LIG_Actin_WH2_2 1791 1808 PF00022 0.347
LIG_Actin_WH2_2 251 269 PF00022 0.554
LIG_Actin_WH2_2 395 412 PF00022 0.247
LIG_BIR_II_1 1 5 PF00653 0.255
LIG_BIR_III_4 1065 1069 PF00653 0.487
LIG_BRCT_BRCA1_1 1749 1753 PF00533 0.275
LIG_BRCT_BRCA1_1 1759 1763 PF00533 0.270
LIG_CaM_IQ_9 892 907 PF13499 0.371
LIG_DLG_GKlike_1 1000 1008 PF00625 0.392
LIG_EH1_1 396 404 PF00400 0.302
LIG_eIF4E_1 1720 1726 PF01652 0.487
LIG_FHA_1 1010 1016 PF00498 0.420
LIG_FHA_1 1083 1089 PF00498 0.487
LIG_FHA_1 1261 1267 PF00498 0.392
LIG_FHA_1 1353 1359 PF00498 0.461
LIG_FHA_1 136 142 PF00498 0.325
LIG_FHA_1 1382 1388 PF00498 0.404
LIG_FHA_1 1450 1456 PF00498 0.463
LIG_FHA_1 1563 1569 PF00498 0.519
LIG_FHA_1 16 22 PF00498 0.361
LIG_FHA_1 1664 1670 PF00498 0.437
LIG_FHA_1 1740 1746 PF00498 0.404
LIG_FHA_1 1767 1773 PF00498 0.350
LIG_FHA_1 1791 1797 PF00498 0.346
LIG_FHA_1 427 433 PF00498 0.298
LIG_FHA_1 481 487 PF00498 0.397
LIG_FHA_1 575 581 PF00498 0.487
LIG_FHA_1 600 606 PF00498 0.350
LIG_FHA_1 746 752 PF00498 0.459
LIG_FHA_1 775 781 PF00498 0.487
LIG_FHA_1 795 801 PF00498 0.410
LIG_FHA_1 810 816 PF00498 0.404
LIG_FHA_1 835 841 PF00498 0.487
LIG_FHA_1 899 905 PF00498 0.469
LIG_FHA_1 961 967 PF00498 0.445
LIG_FHA_2 1111 1117 PF00498 0.447
LIG_FHA_2 1166 1172 PF00498 0.475
LIG_FHA_2 1289 1295 PF00498 0.420
LIG_FHA_2 1414 1420 PF00498 0.533
LIG_FHA_2 1462 1468 PF00498 0.400
LIG_FHA_2 1632 1638 PF00498 0.542
LIG_FHA_2 1647 1653 PF00498 0.404
LIG_FHA_2 18 24 PF00498 0.524
LIG_FHA_2 32 38 PF00498 0.310
LIG_FHA_2 459 465 PF00498 0.397
LIG_FHA_2 533 539 PF00498 0.487
LIG_FHA_2 564 570 PF00498 0.392
LIG_FHA_2 571 577 PF00498 0.392
LIG_FHA_2 69 75 PF00498 0.321
LIG_FHA_2 709 715 PF00498 0.392
LIG_FHA_2 744 750 PF00498 0.372
LIG_FHA_2 804 810 PF00498 0.440
LIG_GBD_Chelix_1 1306 1314 PF00786 0.220
LIG_Integrin_RGD_1 243 245 PF01839 0.374
LIG_KLC1_Yacidic_2 1167 1171 PF13176 0.391
LIG_LIR_Apic_2 1652 1658 PF02991 0.344
LIG_LIR_Apic_2 263 268 PF02991 0.369
LIG_LIR_Gen_1 1019 1026 PF02991 0.421
LIG_LIR_Gen_1 1557 1568 PF02991 0.436
LIG_LIR_Gen_1 159 168 PF02991 0.363
LIG_LIR_Gen_1 1634 1641 PF02991 0.452
LIG_LIR_Gen_1 1666 1676 PF02991 0.447
LIG_LIR_Gen_1 1717 1727 PF02991 0.512
LIG_LIR_Gen_1 480 490 PF02991 0.278
LIG_LIR_Gen_1 576 587 PF02991 0.420
LIG_LIR_Gen_1 643 654 PF02991 0.392
LIG_LIR_Gen_1 66 77 PF02991 0.250
LIG_LIR_Gen_1 721 730 PF02991 0.393
LIG_LIR_LC3C_4 1053 1057 PF02991 0.445
LIG_LIR_Nem_3 1557 1563 PF02991 0.394
LIG_LIR_Nem_3 159 163 PF02991 0.247
LIG_LIR_Nem_3 1597 1602 PF02991 0.368
LIG_LIR_Nem_3 1634 1639 PF02991 0.452
LIG_LIR_Nem_3 1666 1671 PF02991 0.447
LIG_LIR_Nem_3 1699 1705 PF02991 0.407
LIG_LIR_Nem_3 1710 1716 PF02991 0.412
LIG_LIR_Nem_3 1717 1723 PF02991 0.404
LIG_LIR_Nem_3 283 287 PF02991 0.364
LIG_LIR_Nem_3 390 396 PF02991 0.231
LIG_LIR_Nem_3 443 448 PF02991 0.262
LIG_LIR_Nem_3 480 485 PF02991 0.266
LIG_LIR_Nem_3 535 539 PF02991 0.487
LIG_LIR_Nem_3 576 582 PF02991 0.420
LIG_LIR_Nem_3 643 649 PF02991 0.394
LIG_LIR_Nem_3 66 72 PF02991 0.301
LIG_LIR_Nem_3 721 725 PF02991 0.393
LIG_LYPXL_S_1 371 375 PF13949 0.282
LIG_LYPXL_yS_3 372 375 PF13949 0.281
LIG_NRBOX 1268 1274 PF00104 0.392
LIG_PCNA_TLS_4 1163 1170 PF02747 0.391
LIG_PCNA_yPIPBox_3 1064 1074 PF02747 0.450
LIG_PCNA_yPIPBox_3 472 482 PF02747 0.309
LIG_PCNA_yPIPBox_3 744 758 PF02747 0.344
LIG_PCNA_yPIPBox_3 842 856 PF02747 0.487
LIG_Pex14_1 1632 1636 PF04695 0.420
LIG_Pex14_2 151 155 PF04695 0.256
LIG_Pex14_2 1668 1672 PF04695 0.420
LIG_Pex14_2 1753 1757 PF04695 0.276
LIG_Pex14_2 348 352 PF04695 0.451
LIG_REV1ctd_RIR_1 148 157 PF16727 0.259
LIG_REV1ctd_RIR_1 395 404 PF16727 0.227
LIG_SH2_CRK 110 114 PF00017 0.486
LIG_SH2_CRK 1275 1279 PF00017 0.445
LIG_SH2_CRK 1702 1706 PF00017 0.404
LIG_SH2_CRK 482 486 PF00017 0.275
LIG_SH2_CRK 727 731 PF00017 0.445
LIG_SH2_GRB2like 311 314 PF00017 0.197
LIG_SH2_GRB2like 482 485 PF00017 0.197
LIG_SH2_GRB2like 648 651 PF00017 0.392
LIG_SH2_NCK_1 1135 1139 PF00017 0.344
LIG_SH2_NCK_1 1275 1279 PF00017 0.445
LIG_SH2_SRC 1006 1009 PF00017 0.349
LIG_SH2_SRC 648 651 PF00017 0.392
LIG_SH2_STAP1 1020 1024 PF00017 0.392
LIG_SH2_STAP1 1135 1139 PF00017 0.344
LIG_SH2_STAP1 1641 1645 PF00017 0.487
LIG_SH2_STAP1 1716 1720 PF00017 0.458
LIG_SH2_STAP1 384 388 PF00017 0.281
LIG_SH2_STAP1 482 486 PF00017 0.338
LIG_SH2_STAP1 69 73 PF00017 0.366
LIG_SH2_STAT5 1020 1023 PF00017 0.392
LIG_SH2_STAT5 112 115 PF00017 0.498
LIG_SH2_STAT5 1169 1172 PF00017 0.404
LIG_SH2_STAT5 12 15 PF00017 0.330
LIG_SH2_STAT5 1225 1228 PF00017 0.479
LIG_SH2_STAT5 1641 1644 PF00017 0.487
LIG_SH2_STAT5 311 314 PF00017 0.305
LIG_SH2_STAT5 347 350 PF00017 0.334
LIG_SH2_STAT5 446 449 PF00017 0.410
LIG_SH2_STAT5 482 485 PF00017 0.398
LIG_SH2_STAT5 517 520 PF00017 0.487
LIG_SH2_STAT5 596 599 PF00017 0.420
LIG_SH2_STAT5 648 651 PF00017 0.392
LIG_SH2_STAT5 687 690 PF00017 0.404
LIG_SH2_STAT5 775 778 PF00017 0.445
LIG_SH2_STAT5 805 808 PF00017 0.445
LIG_SH3_1 117 123 PF00018 0.445
LIG_SH3_1 55 61 PF00018 0.344
LIG_SH3_2 120 125 PF14604 0.488
LIG_SH3_2 405 410 PF14604 0.257
LIG_SH3_3 117 123 PF00018 0.428
LIG_SH3_3 129 135 PF00018 0.418
LIG_SH3_3 1590 1596 PF00018 0.474
LIG_SH3_3 227 233 PF00018 0.444
LIG_SH3_3 402 408 PF00018 0.253
LIG_SH3_3 509 515 PF00018 0.392
LIG_SH3_3 521 527 PF00018 0.392
LIG_SH3_3 55 61 PF00018 0.344
LIG_SH3_3 737 743 PF00018 0.359
LIG_SH3_3 753 759 PF00018 0.402
LIG_SUMO_SIM_anti_2 128 134 PF11976 0.487
LIG_SUMO_SIM_anti_2 1355 1361 PF11976 0.420
LIG_SUMO_SIM_anti_2 29 37 PF11976 0.351
LIG_SUMO_SIM_par_1 1590 1598 PF11976 0.484
LIG_SUMO_SIM_par_1 210 216 PF11976 0.461
LIG_SUMO_SIM_par_1 708 714 PF11976 0.404
LIG_SUMO_SIM_par_1 890 898 PF11976 0.524
LIG_SUMO_SIM_par_1 910 918 PF11976 0.303
LIG_TRAF2_1 1113 1116 PF00917 0.487
LIG_TRAF2_1 1293 1296 PF00917 0.410
LIG_TRAF2_1 461 464 PF00917 0.468
LIG_TRFH_1 517 521 PF08558 0.400
LIG_TYR_ITIM 1273 1278 PF00017 0.445
LIG_TYR_ITIM 1718 1723 PF00017 0.487
LIG_UBA3_1 1705 1714 PF00899 0.445
LIG_UBA3_1 495 503 PF00899 0.299
LIG_UBA3_1 548 552 PF00899 0.385
LIG_UBA3_1 709 715 PF00899 0.354
LIG_UBA3_1 750 758 PF00899 0.424
LIG_UBA3_1 835 842 PF00899 0.445
LIG_WRC_WIRS_1 1249 1254 PF05994 0.392
LIG_WRC_WIRS_1 1380 1385 PF05994 0.404
LIG_WRC_WIRS_1 1387 1392 PF05994 0.404
LIG_WRC_WIRS_1 281 286 PF05994 0.423
LIG_WRC_WIRS_1 486 491 PF05994 0.200
LIG_WRC_WIRS_1 69 74 PF05994 0.333
LIG_WRC_WIRS_1 991 996 PF05994 0.400
LIG_WW_2 405 408 PF00397 0.245
MOD_CDC14_SPxK_1 544 547 PF00782 0.487
MOD_CDK_SPK_2 295 300 PF00069 0.330
MOD_CDK_SPxK_1 541 547 PF00069 0.487
MOD_CDK_SPxxK_3 1510 1517 PF00069 0.493
MOD_CK1_1 1165 1171 PF00069 0.552
MOD_CK1_1 1254 1260 PF00069 0.393
MOD_CK1_1 1329 1335 PF00069 0.456
MOD_CK1_1 1483 1489 PF00069 0.493
MOD_CK1_1 1510 1516 PF00069 0.510
MOD_CK1_1 1605 1611 PF00069 0.552
MOD_CK1_1 1631 1637 PF00069 0.438
MOD_CK1_1 1777 1783 PF00069 0.352
MOD_CK1_1 2 8 PF00069 0.259
MOD_CK1_1 26 32 PF00069 0.417
MOD_CK1_1 387 393 PF00069 0.311
MOD_CK1_1 511 517 PF00069 0.392
MOD_CK1_1 571 577 PF00069 0.489
MOD_CK1_1 987 993 PF00069 0.392
MOD_CK2_1 1110 1116 PF00069 0.438
MOD_CK2_1 1126 1132 PF00069 0.374
MOD_CK2_1 1165 1171 PF00069 0.471
MOD_CK2_1 1290 1296 PF00069 0.344
MOD_CK2_1 1372 1378 PF00069 0.399
MOD_CK2_1 1399 1405 PF00069 0.445
MOD_CK2_1 1461 1467 PF00069 0.400
MOD_CK2_1 1516 1522 PF00069 0.496
MOD_CK2_1 1646 1652 PF00069 0.445
MOD_CK2_1 17 23 PF00069 0.553
MOD_CK2_1 280 286 PF00069 0.413
MOD_CK2_1 449 455 PF00069 0.353
MOD_CK2_1 458 464 PF00069 0.406
MOD_CK2_1 532 538 PF00069 0.392
MOD_CK2_1 563 569 PF00069 0.392
MOD_CK2_1 570 576 PF00069 0.392
MOD_CK2_1 743 749 PF00069 0.379
MOD_Cter_Amidation 1101 1104 PF01082 0.220
MOD_Cter_Amidation 501 504 PF01082 0.221
MOD_Cter_Amidation 978 981 PF01082 0.220
MOD_GlcNHglycan 1012 1015 PF01048 0.277
MOD_GlcNHglycan 1040 1043 PF01048 0.192
MOD_GlcNHglycan 1253 1256 PF01048 0.204
MOD_GlcNHglycan 1319 1322 PF01048 0.256
MOD_GlcNHglycan 1328 1331 PF01048 0.303
MOD_GlcNHglycan 1347 1350 PF01048 0.287
MOD_GlcNHglycan 1425 1429 PF01048 0.225
MOD_GlcNHglycan 1461 1464 PF01048 0.255
MOD_GlcNHglycan 1483 1486 PF01048 0.306
MOD_GlcNHglycan 1507 1510 PF01048 0.206
MOD_GlcNHglycan 1554 1557 PF01048 0.324
MOD_GlcNHglycan 1699 1702 PF01048 0.220
MOD_GlcNHglycan 1747 1750 PF01048 0.227
MOD_GlcNHglycan 1780 1783 PF01048 0.339
MOD_GlcNHglycan 25 28 PF01048 0.522
MOD_GlcNHglycan 254 257 PF01048 0.400
MOD_GlcNHglycan 260 263 PF01048 0.332
MOD_GlcNHglycan 412 415 PF01048 0.317
MOD_GlcNHglycan 419 422 PF01048 0.354
MOD_GlcNHglycan 573 576 PF01048 0.245
MOD_GlcNHglycan 638 641 PF01048 0.192
MOD_GlcNHglycan 691 694 PF01048 0.192
MOD_GlcNHglycan 769 772 PF01048 0.158
MOD_GlcNHglycan 816 819 PF01048 0.235
MOD_GlcNHglycan 955 958 PF01048 0.192
MOD_GlcNHglycan 986 989 PF01048 0.204
MOD_GSK3_1 1031 1038 PF00069 0.392
MOD_GSK3_1 1106 1113 PF00069 0.445
MOD_GSK3_1 1165 1172 PF00069 0.410
MOD_GSK3_1 1211 1218 PF00069 0.445
MOD_GSK3_1 1241 1248 PF00069 0.392
MOD_GSK3_1 1251 1258 PF00069 0.392
MOD_GSK3_1 1317 1324 PF00069 0.417
MOD_GSK3_1 1326 1333 PF00069 0.358
MOD_GSK3_1 1345 1352 PF00069 0.430
MOD_GSK3_1 1368 1375 PF00069 0.424
MOD_GSK3_1 1379 1386 PF00069 0.457
MOD_GSK3_1 1414 1421 PF00069 0.472
MOD_GSK3_1 1445 1452 PF00069 0.408
MOD_GSK3_1 1459 1466 PF00069 0.455
MOD_GSK3_1 1533 1540 PF00069 0.555
MOD_GSK3_1 1550 1557 PF00069 0.383
MOD_GSK3_1 1602 1609 PF00069 0.421
MOD_GSK3_1 1739 1746 PF00069 0.437
MOD_GSK3_1 1753 1760 PF00069 0.252
MOD_GSK3_1 1766 1773 PF00069 0.315
MOD_GSK3_1 1774 1781 PF00069 0.245
MOD_GSK3_1 246 253 PF00069 0.534
MOD_GSK3_1 28 35 PF00069 0.405
MOD_GSK3_1 295 302 PF00069 0.325
MOD_GSK3_1 343 350 PF00069 0.420
MOD_GSK3_1 415 422 PF00069 0.325
MOD_GSK3_1 426 433 PF00069 0.317
MOD_GSK3_1 570 577 PF00069 0.496
MOD_GSK3_1 599 606 PF00069 0.387
MOD_GSK3_1 636 643 PF00069 0.392
MOD_GSK3_1 68 75 PF00069 0.395
MOD_GSK3_1 739 746 PF00069 0.456
MOD_GSK3_1 779 786 PF00069 0.388
MOD_GSK3_1 790 797 PF00069 0.419
MOD_GSK3_1 801 808 PF00069 0.381
MOD_GSK3_1 830 837 PF00069 0.445
MOD_GSK3_1 844 851 PF00069 0.445
MOD_GSK3_1 89 96 PF00069 0.298
MOD_GSK3_1 949 956 PF00069 0.482
MOD_LATS_1 1503 1509 PF00433 0.344
MOD_N-GLC_1 1066 1071 PF02516 0.192
MOD_N-GLC_1 1105 1110 PF02516 0.230
MOD_N-GLC_1 123 128 PF02516 0.467
MOD_N-GLC_1 1533 1538 PF02516 0.144
MOD_N-GLC_1 1602 1607 PF02516 0.221
MOD_N-GLC_1 1739 1744 PF02516 0.204
MOD_N-GLC_1 203 208 PF02516 0.512
MOD_N-GLC_1 258 263 PF02516 0.277
MOD_N-GLC_1 449 454 PF02516 0.312
MOD_N-GLC_1 649 654 PF02516 0.245
MOD_N-GLC_1 743 748 PF02516 0.144
MOD_N-GLC_1 848 853 PF02516 0.245
MOD_N-GLC_2 289 291 PF02516 0.326
MOD_NEK2_1 1 6 PF00069 0.389
MOD_NEK2_1 1031 1036 PF00069 0.392
MOD_NEK2_1 1083 1088 PF00069 0.487
MOD_NEK2_1 1105 1110 PF00069 0.344
MOD_NEK2_1 1358 1363 PF00069 0.404
MOD_NEK2_1 1372 1377 PF00069 0.399
MOD_NEK2_1 1383 1388 PF00069 0.412
MOD_NEK2_1 1413 1418 PF00069 0.477
MOD_NEK2_1 1537 1542 PF00069 0.421
MOD_NEK2_1 1569 1574 PF00069 0.384
MOD_NEK2_1 1582 1587 PF00069 0.379
MOD_NEK2_1 1692 1697 PF00069 0.445
MOD_NEK2_1 1753 1758 PF00069 0.377
MOD_NEK2_1 1763 1768 PF00069 0.287
MOD_NEK2_1 326 331 PF00069 0.435
MOD_NEK2_1 348 353 PF00069 0.445
MOD_NEK2_1 409 414 PF00069 0.303
MOD_NEK2_1 458 463 PF00069 0.415
MOD_NEK2_1 539 544 PF00069 0.420
MOD_NEK2_1 568 573 PF00069 0.344
MOD_NEK2_1 599 604 PF00069 0.346
MOD_NEK2_1 72 77 PF00069 0.395
MOD_NEK2_1 794 799 PF00069 0.404
MOD_NEK2_1 876 881 PF00069 0.404
MOD_NEK2_1 951 956 PF00069 0.392
MOD_NEK2_2 1018 1023 PF00069 0.392
MOD_NEK2_2 1059 1064 PF00069 0.392
MOD_NEK2_2 1658 1663 PF00069 0.395
MOD_NEK2_2 1670 1675 PF00069 0.448
MOD_NEK2_2 280 285 PF00069 0.414
MOD_NEK2_2 603 608 PF00069 0.487
MOD_NEK2_2 640 645 PF00069 0.392
MOD_OFUCOSY 841 848 PF10250 0.144
MOD_PIKK_1 1180 1186 PF00454 0.404
MOD_PIKK_1 123 129 PF00454 0.619
MOD_PIKK_1 1242 1248 PF00454 0.392
MOD_PIKK_1 1349 1355 PF00454 0.442
MOD_PIKK_1 135 141 PF00454 0.385
MOD_PIKK_1 1381 1387 PF00454 0.421
MOD_PIKK_1 1414 1420 PF00454 0.485
MOD_PIKK_1 1445 1451 PF00454 0.487
MOD_PIKK_1 1631 1637 PF00454 0.479
MOD_PIKK_1 326 332 PF00454 0.337
MOD_PK_1 1202 1208 PF00069 0.445
MOD_PK_1 1714 1720 PF00069 0.487
MOD_PKA_1 1180 1186 PF00069 0.445
MOD_PKA_1 1714 1720 PF00069 0.487
MOD_PKA_2 1009 1015 PF00069 0.423
MOD_PKA_2 1083 1089 PF00069 0.487
MOD_PKA_2 128 134 PF00069 0.498
MOD_PKA_2 1308 1314 PF00069 0.457
MOD_PKA_2 1413 1419 PF00069 0.421
MOD_PKA_2 1625 1631 PF00069 0.526
MOD_PKA_2 1684 1690 PF00069 0.420
MOD_PKA_2 1714 1720 PF00069 0.445
MOD_PKA_2 23 29 PF00069 0.538
MOD_PKA_2 246 252 PF00069 0.549
MOD_PKA_2 299 305 PF00069 0.286
MOD_PKA_2 348 354 PF00069 0.441
MOD_PKA_2 362 368 PF00069 0.398
MOD_PKA_2 409 415 PF00069 0.306
MOD_PKA_2 786 792 PF00069 0.377
MOD_PKA_2 898 904 PF00069 0.462
MOD_PKB_1 1788 1796 PF00069 0.358
MOD_Plk_1 1018 1024 PF00069 0.392
MOD_Plk_1 1059 1065 PF00069 0.392
MOD_Plk_1 1202 1208 PF00069 0.509
MOD_Plk_1 1602 1608 PF00069 0.421
MOD_Plk_1 1774 1780 PF00069 0.303
MOD_Plk_1 203 209 PF00069 0.411
MOD_Plk_1 363 369 PF00069 0.296
MOD_Plk_1 376 382 PF00069 0.303
MOD_Plk_1 568 574 PF00069 0.344
MOD_Plk_1 743 749 PF00069 0.380
MOD_Plk_1 848 854 PF00069 0.487
MOD_Plk_2-3 1288 1294 PF00069 0.487
MOD_Plk_4 1051 1057 PF00069 0.400
MOD_Plk_4 1066 1072 PF00069 0.370
MOD_Plk_4 1165 1171 PF00069 0.462
MOD_Plk_4 128 134 PF00069 0.498
MOD_Plk_4 1533 1539 PF00069 0.344
MOD_Plk_4 1619 1625 PF00069 0.419
MOD_Plk_4 1628 1634 PF00069 0.348
MOD_Plk_4 1721 1727 PF00069 0.404
MOD_Plk_4 203 209 PF00069 0.411
MOD_Plk_4 28 34 PF00069 0.371
MOD_Plk_4 343 349 PF00069 0.366
MOD_Plk_4 363 369 PF00069 0.165
MOD_Plk_4 387 393 PF00069 0.279
MOD_Plk_4 419 425 PF00069 0.340
MOD_Plk_4 626 632 PF00069 0.392
MOD_Plk_4 68 74 PF00069 0.320
MOD_Plk_4 718 724 PF00069 0.404
MOD_Plk_4 795 801 PF00069 0.404
MOD_Plk_4 848 854 PF00069 0.487
MOD_Plk_4 990 996 PF00069 0.400
MOD_ProDKin_1 1335 1341 PF00069 0.497
MOD_ProDKin_1 1449 1455 PF00069 0.487
MOD_ProDKin_1 1510 1516 PF00069 0.461
MOD_ProDKin_1 1747 1753 PF00069 0.429
MOD_ProDKin_1 295 301 PF00069 0.308
MOD_ProDKin_1 450 456 PF00069 0.346
MOD_ProDKin_1 511 517 PF00069 0.392
MOD_ProDKin_1 541 547 PF00069 0.487
MOD_ProDKin_1 739 745 PF00069 0.344
MOD_SUMO_for_1 490 493 PF00179 0.264
MOD_SUMO_rev_2 1165 1174 PF00179 0.487
TRG_DiLeu_BaEn_1 1230 1235 PF01217 0.392
TRG_DiLeu_BaEn_1 140 145 PF01217 0.290
TRG_DiLeu_BaEn_1 676 681 PF01217 0.392
TRG_DiLeu_BaEn_2 178 184 PF01217 0.300
TRG_DiLeu_LyEn_5 1578 1583 PF01217 0.480
TRG_ENDOCYTIC_2 110 113 PF00928 0.481
TRG_ENDOCYTIC_2 1176 1179 PF00928 0.487
TRG_ENDOCYTIC_2 1209 1212 PF00928 0.420
TRG_ENDOCYTIC_2 1275 1278 PF00928 0.445
TRG_ENDOCYTIC_2 1560 1563 PF00928 0.392
TRG_ENDOCYTIC_2 1702 1705 PF00928 0.409
TRG_ENDOCYTIC_2 1720 1723 PF00928 0.404
TRG_ENDOCYTIC_2 372 375 PF00928 0.281
TRG_ENDOCYTIC_2 393 396 PF00928 0.247
TRG_ENDOCYTIC_2 445 448 PF00928 0.286
TRG_ENDOCYTIC_2 482 485 PF00928 0.281
TRG_ENDOCYTIC_2 596 599 PF00928 0.410
TRG_ENDOCYTIC_2 69 72 PF00928 0.295
TRG_ENDOCYTIC_2 727 730 PF00928 0.392
TRG_ER_diArg_1 116 118 PF00400 0.471
TRG_ER_diArg_1 1219 1221 PF00400 0.421
TRG_ER_diArg_1 1267 1270 PF00400 0.392
TRG_ER_diArg_1 1398 1401 PF00400 0.404
TRG_ER_diArg_1 16 19 PF00400 0.362
TRG_ER_diArg_1 1674 1677 PF00400 0.528
TRG_ER_diArg_1 1788 1791 PF00400 0.338
TRG_ER_diArg_1 195 198 PF00400 0.497
TRG_ER_diArg_1 199 201 PF00400 0.477
TRG_ER_diArg_1 222 225 PF00400 0.402
TRG_ER_diArg_1 46 49 PF00400 0.330
TRG_ER_diArg_1 588 590 PF00400 0.487
TRG_ER_diArg_1 63 65 PF00400 0.331
TRG_ER_diArg_1 980 982 PF00400 0.420
TRG_NES_CRM1_1 1688 1699 PF08389 0.420
TRG_NLS_Bipartite_1 1504 1521 PF00514 0.413
TRG_NLS_MonoExtC_3 1516 1522 PF00514 0.519
TRG_NLS_MonoExtC_3 1572 1578 PF00514 0.421
TRG_NLS_MonoExtN_4 1514 1521 PF00514 0.509
TRG_NLS_MonoExtN_4 1680 1686 PF00514 0.354
TRG_Pf-PMV_PEXEL_1 1146 1150 PF00026 0.282
TRG_Pf-PMV_PEXEL_1 1733 1737 PF00026 0.200
TRG_Pf-PMV_PEXEL_1 1770 1774 PF00026 0.352
TRG_Pf-PMV_PEXEL_1 430 434 PF00026 0.324
TRG_Pf-PMV_PEXEL_1 609 613 PF00026 0.204

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I4V8 Leptomonas seymouri 84% 100%
A0A0S4JSQ7 Bodo saltans 56% 95%
A0A1X0NZF6 Trypanosomatidae 62% 96%
A0A3S7WU48 Leishmania donovani 90% 100%
A4HX31 Leishmania infantum 90% 100%
C9ZVW2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 53% 100%
E9AQU6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
P10964 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 30% 100%
P15398 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 31% 100%
P16355 Trypanosoma brucei brucei 53% 100%
P91875 Drosophila melanogaster 30% 100%
Q4QEN2 Leishmania major 91% 100%
Q86H36 Dictyostelium discoideum 31% 100%
V5BMM9 Trypanosoma cruzi 56% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS