Sucrose-phosphate synthase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

sucrose-phosphate synthase-like protein

Species:

Leishmania braziliensis

UniProt:

A4H8L9_LEIBR

TriTrypDb:

LbrM.16.0960 , LBRM2903_160016100

Length:

493

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 16

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 7

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H8L9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H8L9

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	8
GO:0008194	UDP-glycosyltransferase activity	4	6
GO:0016740	transferase activity	2	8
GO:0016757	glycosyltransferase activity	3	8
GO:0016758	hexosyltransferase activity	4	6
GO:0035251	UDP-glucosyltransferase activity	5	6
GO:0046524	sucrose-phosphate synthase activity	6	6
GO:0046527	glucosyltransferase activity	5	6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	169	171	PF00675	0.462
CLV_NRD_NRD_1	353	355	PF00675	0.433
CLV_PCSK_KEX2_1	112	114	PF00082	0.528
CLV_PCSK_KEX2_1	14	16	PF00082	0.448
CLV_PCSK_KEX2_1	146	148	PF00082	0.482
CLV_PCSK_KEX2_1	169	171	PF00082	0.465
CLV_PCSK_KEX2_1	322	324	PF00082	0.376
CLV_PCSK_PC1ET2_1	112	114	PF00082	0.528
CLV_PCSK_PC1ET2_1	14	16	PF00082	0.448
CLV_PCSK_PC1ET2_1	146	148	PF00082	0.482
CLV_PCSK_PC1ET2_1	322	324	PF00082	0.376
CLV_PCSK_SKI1_1	214	218	PF00082	0.483
CLV_PCSK_SKI1_1	26	30	PF00082	0.410
CLV_PCSK_SKI1_1	339	343	PF00082	0.433
CLV_PCSK_SKI1_1	451	455	PF00082	0.566
CLV_PCSK_SKI1_1	459	463	PF00082	0.432
DEG_Nend_UBRbox_3	1	3	PF02207	0.485
DOC_CKS1_1	82	87	PF01111	0.614
DOC_CYCLIN_yCln2_LP_2	6	12	PF00134	0.458
DOC_MAPK_DCC_7	170	180	PF00069	0.473
DOC_MAPK_DCC_7	92	102	PF00069	0.512
DOC_MAPK_gen_1	14	22	PF00069	0.489
DOC_MAPK_gen_1	142	152	PF00069	0.480
DOC_MAPK_gen_1	336	346	PF00069	0.487
DOC_MAPK_HePTP_8	12	24	PF00069	0.432
DOC_MAPK_HePTP_8	140	152	PF00069	0.476
DOC_MAPK_MEF2A_6	14	22	PF00069	0.430
DOC_MAPK_MEF2A_6	143	152	PF00069	0.451
DOC_MAPK_MEF2A_6	339	346	PF00069	0.501
DOC_MAPK_NFAT4_5	15	23	PF00069	0.430
DOC_MAPK_NFAT4_5	339	347	PF00069	0.501
DOC_PP1_RVXF_1	308	315	PF00149	0.376
DOC_PP2B_LxvP_1	6	9	PF13499	0.468
DOC_PP4_FxxP_1	157	160	PF00568	0.398
DOC_PP4_FxxP_1	372	375	PF00568	0.376
DOC_USP7_MATH_1	108	112	PF00917	0.569
DOC_USP7_MATH_1	303	307	PF00917	0.353
DOC_USP7_UBL2_3	142	146	PF12436	0.473
DOC_USP7_UBL2_3	336	340	PF12436	0.303
DOC_WW_Pin1_4	249	254	PF00397	0.468
DOC_WW_Pin1_4	409	414	PF00397	0.376
DOC_WW_Pin1_4	81	86	PF00397	0.538
LIG_14-3-3_CanoR_1	113	118	PF00244	0.474
LIG_14-3-3_CanoR_1	15	21	PF00244	0.530
LIG_Actin_WH2_2	353	370	PF00022	0.376
LIG_BRCT_BRCA1_1	223	227	PF00533	0.468
LIG_BRCT_BRCA1_1	46	50	PF00533	0.565
LIG_Clathr_ClatBox_1	243	247	PF01394	0.318
LIG_Clathr_ClatBox_1	402	406	PF01394	0.376
LIG_deltaCOP1_diTrp_1	33	37	PF00928	0.471
LIG_FHA_1	211	217	PF00498	0.508
LIG_FHA_1	218	224	PF00498	0.523
LIG_FHA_1	351	357	PF00498	0.509
LIG_FHA_1	368	374	PF00498	0.248
LIG_FHA_1	410	416	PF00498	0.376
LIG_FHA_2	384	390	PF00498	0.376
LIG_FHA_2	430	436	PF00498	0.411
LIG_FHA_2	476	482	PF00498	0.377
LIG_FHA_2	82	88	PF00498	0.613
LIG_IRF3_LxIS_1	4	11	PF10401	0.464
LIG_LIR_Apic_2	369	375	PF02991	0.433
LIG_LIR_Gen_1	111	122	PF02991	0.448
LIG_LIR_Gen_1	235	245	PF02991	0.488
LIG_LIR_Gen_1	306	314	PF02991	0.262
LIG_LIR_Gen_1	31	39	PF02991	0.425
LIG_LIR_Gen_1	359	367	PF02991	0.501
LIG_LIR_Gen_1	444	455	PF02991	0.501
LIG_LIR_Nem_3	135	139	PF02991	0.462
LIG_LIR_Nem_3	235	240	PF02991	0.444
LIG_LIR_Nem_3	306	311	PF02991	0.339
LIG_LIR_Nem_3	31	37	PF02991	0.433
LIG_LIR_Nem_3	359	365	PF02991	0.447
LIG_LIR_Nem_3	397	403	PF02991	0.376
LIG_LIR_Nem_3	444	450	PF02991	0.501
LIG_LIR_Nem_3	456	461	PF02991	0.341
LIG_LIR_Nem_3	89	94	PF02991	0.456
LIG_Pex14_2	237	241	PF04695	0.431
LIG_Pex14_2	314	318	PF04695	0.376
LIG_Pex14_2	400	404	PF04695	0.376
LIG_SH2_CRK	256	260	PF00017	0.499
LIG_SH2_CRK	308	312	PF00017	0.430
LIG_SH2_CRK	447	451	PF00017	0.430
LIG_SH2_GRB2like	192	195	PF00017	0.436
LIG_SH2_NCK_1	385	389	PF00017	0.501
LIG_SH2_SRC	94	97	PF00017	0.473
LIG_SH2_STAP1	192	196	PF00017	0.495
LIG_SH2_STAP1	308	312	PF00017	0.430
LIG_SH2_STAT5	125	128	PF00017	0.488
LIG_SH2_STAT5	139	142	PF00017	0.480
LIG_SH2_STAT5	357	360	PF00017	0.387
LIG_SH2_STAT5	385	388	PF00017	0.430
LIG_SH3_1	239	245	PF00018	0.492
LIG_SH3_2	200	205	PF14604	0.524
LIG_SH3_3	173	179	PF00018	0.468
LIG_SH3_3	197	203	PF00018	0.533
LIG_SH3_3	239	245	PF00018	0.443
LIG_SH3_3	257	263	PF00018	0.353
LIG_SUMO_SIM_par_1	386	391	PF11976	0.249
LIG_TRAF2_1	118	121	PF00917	0.487
LIG_TRAF2_1	395	398	PF00917	0.311
LIG_TRFH_1	241	245	PF08558	0.561
LIG_TRFH_1	371	375	PF08558	0.376
LIG_UBA3_1	6	14	PF00899	0.516
MOD_CDK_SPxxK_3	81	88	PF00069	0.577
MOD_CK1_1	350	356	PF00069	0.399
MOD_CK1_1	475	481	PF00069	0.443
MOD_CK2_1	115	121	PF00069	0.477
MOD_CK2_1	212	218	PF00069	0.323
MOD_CK2_1	232	238	PF00069	0.237
MOD_CK2_1	329	335	PF00069	0.430
MOD_CK2_1	392	398	PF00069	0.376
MOD_CK2_1	435	441	PF00069	0.430
MOD_CK2_1	475	481	PF00069	0.503
MOD_Cter_Amidation	144	147	PF01082	0.502
MOD_GlcNHglycan	223	226	PF01048	0.426
MOD_GlcNHglycan	229	232	PF01048	0.483
MOD_GlcNHglycan	305	308	PF01048	0.448
MOD_GlcNHglycan	418	421	PF01048	0.376
MOD_GlcNHglycan	53	56	PF01048	0.508
MOD_GSK3_1	121	128	PF00069	0.528
MOD_GSK3_1	217	224	PF00069	0.506
MOD_GSK3_1	22	29	PF00069	0.503
MOD_GSK3_1	284	291	PF00069	0.605
MOD_GSK3_1	388	395	PF00069	0.464
MOD_GSK3_1	72	79	PF00069	0.415
MOD_N-GLC_1	303	308	PF02516	0.473
MOD_N-GLC_2	69	71	PF02516	0.321
MOD_NEK2_1	217	222	PF00069	0.489
MOD_NEK2_1	227	232	PF00069	0.499
MOD_NEK2_1	24	29	PF00069	0.491
MOD_NEK2_1	284	289	PF00069	0.621
MOD_NEK2_1	367	372	PF00069	0.430
MOD_NEK2_1	474	479	PF00069	0.459
MOD_NEK2_1	486	491	PF00069	0.519
MOD_NEK2_1	67	72	PF00069	0.314
MOD_NEK2_2	212	217	PF00069	0.327
MOD_PIKK_1	284	290	PF00454	0.689
MOD_PIKK_1	347	353	PF00454	0.501
MOD_PIKK_1	374	380	PF00454	0.430
MOD_PIKK_1	475	481	PF00454	0.471
MOD_PK_1	323	329	PF00069	0.423
MOD_PKA_1	472	478	PF00069	0.495
MOD_PKA_2	210	216	PF00069	0.508
MOD_Plk_1	120	126	PF00069	0.461
MOD_Plk_1	284	290	PF00069	0.698
MOD_Plk_1	303	309	PF00069	0.341
MOD_Plk_1	388	394	PF00069	0.501
MOD_Plk_2-3	121	127	PF00069	0.501
MOD_Plk_2-3	424	430	PF00069	0.335
MOD_Plk_4	125	131	PF00069	0.299
MOD_Plk_4	212	218	PF00069	0.323
MOD_Plk_4	323	329	PF00069	0.430
MOD_Plk_4	340	346	PF00069	0.376
MOD_Plk_4	367	373	PF00069	0.420
MOD_Plk_4	383	389	PF00069	0.265
MOD_Plk_4	429	435	PF00069	0.311
MOD_Plk_4	72	78	PF00069	0.458
MOD_ProDKin_1	249	255	PF00069	0.466
MOD_ProDKin_1	409	415	PF00069	0.376
MOD_ProDKin_1	81	87	PF00069	0.545
MOD_SUMO_rev_2	332	342	PF00179	0.501
MOD_SUMO_rev_2	456	461	PF00179	0.501
TRG_DiLeu_BaEn_1	398	403	PF01217	0.376
TRG_DiLeu_BaEn_1	429	434	PF01217	0.462
TRG_DiLeu_BaEn_2	131	137	PF01217	0.473
TRG_ENDOCYTIC_2	207	210	PF00928	0.432
TRG_ENDOCYTIC_2	256	259	PF00928	0.498
TRG_ENDOCYTIC_2	281	284	PF00928	0.549
TRG_ENDOCYTIC_2	308	311	PF00928	0.430
TRG_ENDOCYTIC_2	357	360	PF00928	0.376
TRG_ENDOCYTIC_2	362	365	PF00928	0.376
TRG_ENDOCYTIC_2	385	388	PF00928	0.249
TRG_ENDOCYTIC_2	447	450	PF00928	0.430
TRG_ER_diArg_1	169	171	PF00400	0.519
TRG_Pf-PMV_PEXEL_1	354	359	PF00026	0.501

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILL5	Leptomonas seymouri	79%	100%
A0A0R6YAV9	Leishmania donovani	91%	100%
A0A0S4JKT8	Bodo saltans	46%	90%
A4HWZ0	Leishmania infantum	90%	100%
E9AQQ4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4QES5	Leishmania major	90%	100%