LysM domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H8J2_LEIBR

TriTrypDb:

LbrM.16.0690 , LBRM2903_160013300

Length:

858

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H8J2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H8J2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	202	206	PF00656	0.549
CLV_C14_Caspase3-7	70	74	PF00656	0.514
CLV_C14_Caspase3-7	813	817	PF00656	0.537
CLV_MEL_PAP_1	660	666	PF00089	0.552
CLV_NRD_NRD_1	314	316	PF00675	0.573
CLV_NRD_NRD_1	442	444	PF00675	0.639
CLV_NRD_NRD_1	5	7	PF00675	0.370
CLV_NRD_NRD_1	531	533	PF00675	0.567
CLV_NRD_NRD_1	587	589	PF00675	0.572
CLV_NRD_NRD_1	662	664	PF00675	0.558
CLV_NRD_NRD_1	690	692	PF00675	0.705
CLV_PCSK_FUR_1	312	316	PF00082	0.573
CLV_PCSK_KEX2_1	203	205	PF00082	0.582
CLV_PCSK_KEX2_1	314	316	PF00082	0.573
CLV_PCSK_KEX2_1	444	446	PF00082	0.654
CLV_PCSK_KEX2_1	5	7	PF00082	0.512
CLV_PCSK_KEX2_1	531	533	PF00082	0.567
CLV_PCSK_KEX2_1	587	589	PF00082	0.572
CLV_PCSK_KEX2_1	662	664	PF00082	0.558
CLV_PCSK_KEX2_1	690	692	PF00082	0.705
CLV_PCSK_KEX2_1	706	708	PF00082	0.552
CLV_PCSK_PC1ET2_1	203	205	PF00082	0.552
CLV_PCSK_PC1ET2_1	444	446	PF00082	0.592
CLV_PCSK_PC1ET2_1	706	708	PF00082	0.559
CLV_PCSK_PC7_1	440	446	PF00082	0.652
CLV_PCSK_PC7_1	702	708	PF00082	0.567
CLV_PCSK_SKI1_1	514	518	PF00082	0.574
CLV_PCSK_SKI1_1	825	829	PF00082	0.522
DEG_APCC_DBOX_1	285	293	PF00400	0.682
DEG_Nend_UBRbox_2	1	3	PF02207	0.524
DEG_ODPH_VHL_1	332	344	PF01847	0.528
DEG_SCF_TRCP1_1	239	245	PF00400	0.672
DEG_SPOP_SBC_1	139	143	PF00917	0.615
DEG_SPOP_SBC_1	167	171	PF00917	0.547
DEG_SPOP_SBC_1	193	197	PF00917	0.676
DEG_SPOP_SBC_1	320	324	PF00917	0.558
DEG_SPOP_SBC_1	600	604	PF00917	0.685
DEG_SPOP_SBC_1	617	621	PF00917	0.546
DOC_CKS1_1	581	586	PF01111	0.685
DOC_CYCLIN_yCln2_LP_2	711	717	PF00134	0.527
DOC_CYCLIN_yCln2_LP_2	773	779	PF00134	0.243
DOC_PP2B_LxvP_1	332	335	PF13499	0.596
DOC_PP2B_LxvP_1	711	714	PF13499	0.564
DOC_PP2B_LxvP_1	731	734	PF13499	0.576
DOC_PP2B_LxvP_1	773	776	PF13499	0.243
DOC_PP4_FxxP_1	331	334	PF00568	0.543
DOC_PP4_FxxP_1	581	584	PF00568	0.682
DOC_PP4_MxPP_1	654	657	PF00568	0.692
DOC_USP7_MATH_1	137	141	PF00917	0.637
DOC_USP7_MATH_1	14	18	PF00917	0.380
DOC_USP7_MATH_1	153	157	PF00917	0.492
DOC_USP7_MATH_1	193	197	PF00917	0.676
DOC_USP7_MATH_1	221	225	PF00917	0.587
DOC_USP7_MATH_1	237	241	PF00917	0.520
DOC_USP7_MATH_1	251	255	PF00917	0.620
DOC_USP7_MATH_1	284	288	PF00917	0.523
DOC_USP7_MATH_1	307	311	PF00917	0.666
DOC_USP7_MATH_1	313	317	PF00917	0.700
DOC_USP7_MATH_1	320	324	PF00917	0.621
DOC_USP7_MATH_1	474	478	PF00917	0.605
DOC_USP7_MATH_1	534	538	PF00917	0.646
DOC_USP7_MATH_1	542	546	PF00917	0.659
DOC_USP7_MATH_1	563	567	PF00917	0.688
DOC_USP7_MATH_1	569	573	PF00917	0.659
DOC_USP7_MATH_1	617	621	PF00917	0.583
DOC_USP7_MATH_1	726	730	PF00917	0.610
DOC_USP7_MATH_2	34	40	PF00917	0.544
DOC_WW_Pin1_4	129	134	PF00397	0.552
DOC_WW_Pin1_4	194	199	PF00397	0.537
DOC_WW_Pin1_4	244	249	PF00397	0.688
DOC_WW_Pin1_4	280	285	PF00397	0.656
DOC_WW_Pin1_4	297	302	PF00397	0.652
DOC_WW_Pin1_4	316	321	PF00397	0.532
DOC_WW_Pin1_4	323	328	PF00397	0.676
DOC_WW_Pin1_4	352	357	PF00397	0.710
DOC_WW_Pin1_4	388	393	PF00397	0.664
DOC_WW_Pin1_4	427	432	PF00397	0.592
DOC_WW_Pin1_4	455	460	PF00397	0.588
DOC_WW_Pin1_4	467	472	PF00397	0.658
DOC_WW_Pin1_4	482	487	PF00397	0.556
DOC_WW_Pin1_4	523	528	PF00397	0.702
DOC_WW_Pin1_4	540	545	PF00397	0.518
DOC_WW_Pin1_4	548	553	PF00397	0.582
DOC_WW_Pin1_4	555	560	PF00397	0.525
DOC_WW_Pin1_4	580	585	PF00397	0.643
DOC_WW_Pin1_4	609	614	PF00397	0.695
DOC_WW_Pin1_4	618	623	PF00397	0.609
DOC_WW_Pin1_4	632	637	PF00397	0.591
DOC_WW_Pin1_4	648	653	PF00397	0.550
DOC_WW_Pin1_4	663	668	PF00397	0.543
DOC_WW_Pin1_4	724	729	PF00397	0.574
DOC_WW_Pin1_4	835	840	PF00397	0.675
DOC_WW_Pin1_4	848	853	PF00397	0.566
LIG_14-3-3_CanoR_1	168	176	PF00244	0.546
LIG_14-3-3_CanoR_1	232	238	PF00244	0.530
LIG_14-3-3_CanoR_1	29	34	PF00244	0.456
LIG_14-3-3_CanoR_1	312	320	PF00244	0.753
LIG_14-3-3_CanoR_1	386	392	PF00244	0.570
LIG_14-3-3_CanoR_1	407	411	PF00244	0.677
LIG_14-3-3_CanoR_1	47	54	PF00244	0.519
LIG_14-3-3_CanoR_1	514	523	PF00244	0.574
LIG_14-3-3_CanoR_1	531	541	PF00244	0.607
LIG_14-3-3_CanoR_1	662	667	PF00244	0.625
LIG_BIR_III_4	73	77	PF00653	0.522
LIG_CtBP_PxDLS_1	668	672	PF00389	0.687
LIG_EVH1_2	327	331	PF00568	0.595
LIG_EVH1_2	334	338	PF00568	0.564
LIG_FHA_1	145	151	PF00498	0.556
LIG_FHA_1	152	158	PF00498	0.525
LIG_FHA_1	628	634	PF00498	0.561
LIG_FHA_1	66	72	PF00498	0.536
LIG_FHA_1	710	716	PF00498	0.529
LIG_FHA_1	772	778	PF00498	0.243
LIG_FHA_1	813	819	PF00498	0.588
LIG_FHA_2	11	17	PF00498	0.375
LIG_FHA_2	110	116	PF00498	0.466
LIG_FHA_2	373	379	PF00498	0.593
LIG_FHA_2	569	575	PF00498	0.553
LIG_GBD_Chelix_1	37	45	PF00786	0.457
LIG_IBAR_NPY_1	782	784	PF08397	0.385
LIG_Integrin_RGD_1	411	413	PF01839	0.562
LIG_LIR_Apic_2	330	334	PF02991	0.545
LIG_LIR_Apic_2	580	584	PF02991	0.677
LIG_LIR_Gen_1	122	131	PF02991	0.557
LIG_LIR_Gen_1	758	769	PF02991	0.272
LIG_LIR_Nem_3	122	127	PF02991	0.536
LIG_LIR_Nem_3	337	341	PF02991	0.529
LIG_LIR_Nem_3	758	764	PF02991	0.441
LIG_LIR_Nem_3	780	784	PF02991	0.385
LIG_MYND_1	107	111	PF01753	0.408
LIG_MYND_1	271	275	PF01753	0.505
LIG_MYND_1	523	527	PF01753	0.559
LIG_PDZ_Class_1	853	858	PF00595	0.540
LIG_SH2_STAT5	124	127	PF00017	0.533
LIG_SH2_STAT5	546	549	PF00017	0.549
LIG_SH2_STAT5	784	787	PF00017	0.385
LIG_SH3_1	787	793	PF00018	0.309
LIG_SH3_3	104	110	PF00018	0.503
LIG_SH3_3	115	121	PF00018	0.426
LIG_SH3_3	130	136	PF00018	0.495
LIG_SH3_3	182	188	PF00018	0.522
LIG_SH3_3	245	251	PF00018	0.720
LIG_SH3_3	269	275	PF00018	0.552
LIG_SH3_3	293	299	PF00018	0.575
LIG_SH3_3	322	328	PF00018	0.691
LIG_SH3_3	398	404	PF00018	0.653
LIG_SH3_3	453	459	PF00018	0.599
LIG_SH3_3	481	487	PF00018	0.646
LIG_SH3_3	516	522	PF00018	0.569
LIG_SH3_3	572	578	PF00018	0.579
LIG_SH3_3	630	636	PF00018	0.556
LIG_SH3_3	661	667	PF00018	0.690
LIG_SH3_3	690	696	PF00018	0.636
LIG_SH3_3	717	723	PF00018	0.601
LIG_SH3_3	787	793	PF00018	0.374
LIG_SUMO_SIM_par_1	287	295	PF11976	0.685
LIG_SUMO_SIM_par_1	339	346	PF11976	0.560
LIG_SUMO_SIM_par_1	774	780	PF11976	0.243
LIG_TRAF2_1	749	752	PF00917	0.527
LIG_UBA3_1	289	293	PF00899	0.692
LIG_WW_3	687	691	PF00397	0.677
MOD_CDC14_SPxK_1	283	286	PF00782	0.517
MOD_CDC14_SPxK_1	302	305	PF00782	0.563
MOD_CDC14_SPxK_1	472	475	PF00782	0.693
MOD_CDK_SPK_2	316	321	PF00069	0.578
MOD_CDK_SPK_2	632	637	PF00069	0.677
MOD_CDK_SPxK_1	280	286	PF00069	0.522
MOD_CDK_SPxK_1	299	305	PF00069	0.555
MOD_CDK_SPxK_1	469	475	PF00069	0.692
MOD_CDK_SPxxK_3	455	462	PF00069	0.549
MOD_CDK_SPxxK_3	580	587	PF00069	0.546
MOD_CDK_SPxxK_3	618	625	PF00069	0.550
MOD_CDK_SPxxK_3	648	655	PF00069	0.699
MOD_CK1_1	132	138	PF00069	0.631
MOD_CK1_1	140	146	PF00069	0.621
MOD_CK1_1	162	168	PF00069	0.621
MOD_CK1_1	171	177	PF00069	0.536
MOD_CK1_1	192	198	PF00069	0.675
MOD_CK1_1	199	205	PF00069	0.626
MOD_CK1_1	316	322	PF00069	0.590
MOD_CK1_1	323	329	PF00069	0.673
MOD_CK1_1	371	377	PF00069	0.712
MOD_CK1_1	385	391	PF00069	0.586
MOD_CK1_1	417	423	PF00069	0.564
MOD_CK1_1	458	464	PF00069	0.566
MOD_CK1_1	477	483	PF00069	0.624
MOD_CK1_1	485	491	PF00069	0.637
MOD_CK1_1	535	541	PF00069	0.670
MOD_CK1_1	545	551	PF00069	0.625
MOD_CK1_1	558	564	PF00069	0.579
MOD_CK1_1	612	618	PF00069	0.702
MOD_CK1_1	635	641	PF00069	0.672
MOD_CK1_1	69	75	PF00069	0.658
MOD_CK1_1	724	730	PF00069	0.618
MOD_CK1_1	845	851	PF00069	0.549
MOD_CK2_1	10	16	PF00069	0.363
MOD_CK2_1	109	115	PF00069	0.521
MOD_CK2_1	29	35	PF00069	0.539
MOD_CK2_1	372	378	PF00069	0.713
MOD_CK2_1	486	492	PF00069	0.536
MOD_CK2_1	617	623	PF00069	0.597
MOD_CK2_1	635	641	PF00069	0.582
MOD_CK2_1	726	732	PF00069	0.691
MOD_CK2_1	829	835	PF00069	0.514
MOD_Cter_Amidation	660	663	PF01082	0.555
MOD_Cter_Amidation	704	707	PF01082	0.566
MOD_DYRK1A_RPxSP_1	663	667	PF00069	0.546
MOD_GlcNHglycan	161	164	PF01048	0.643
MOD_GlcNHglycan	165	168	PF01048	0.615
MOD_GlcNHglycan	170	173	PF01048	0.574
MOD_GlcNHglycan	191	194	PF01048	0.674
MOD_GlcNHglycan	198	201	PF01048	0.622
MOD_GlcNHglycan	211	214	PF01048	0.681
MOD_GlcNHglycan	233	236	PF01048	0.625
MOD_GlcNHglycan	239	242	PF01048	0.565
MOD_GlcNHglycan	309	312	PF01048	0.640
MOD_GlcNHglycan	338	341	PF01048	0.538
MOD_GlcNHglycan	359	362	PF01048	0.578
MOD_GlcNHglycan	371	374	PF01048	0.585
MOD_GlcNHglycan	38	41	PF01048	0.457
MOD_GlcNHglycan	416	419	PF01048	0.543
MOD_GlcNHglycan	431	434	PF01048	0.561
MOD_GlcNHglycan	481	484	PF01048	0.685
MOD_GlcNHglycan	534	537	PF01048	0.649
MOD_GlcNHglycan	560	563	PF01048	0.674
MOD_GlcNHglycan	571	574	PF01048	0.624
MOD_GlcNHglycan	596	599	PF01048	0.555
MOD_GlcNHglycan	603	606	PF01048	0.601
MOD_GlcNHglycan	614	617	PF01048	0.671
MOD_GlcNHglycan	702	705	PF01048	0.573
MOD_GlcNHglycan	81	84	PF01048	0.650
MOD_GlcNHglycan	844	847	PF01048	0.662
MOD_GSK3_1	10	17	PF00069	0.388
MOD_GSK3_1	138	145	PF00069	0.643
MOD_GSK3_1	153	160	PF00069	0.504
MOD_GSK3_1	162	169	PF00069	0.580
MOD_GSK3_1	189	196	PF00069	0.671
MOD_GSK3_1	205	212	PF00069	0.548
MOD_GSK3_1	237	244	PF00069	0.687
MOD_GSK3_1	251	258	PF00069	0.635
MOD_GSK3_1	280	287	PF00069	0.690
MOD_GSK3_1	315	322	PF00069	0.596
MOD_GSK3_1	323	330	PF00069	0.588
MOD_GSK3_1	336	343	PF00069	0.543
MOD_GSK3_1	368	375	PF00069	0.715
MOD_GSK3_1	382	389	PF00069	0.589
MOD_GSK3_1	413	420	PF00069	0.569
MOD_GSK3_1	444	451	PF00069	0.568
MOD_GSK3_1	475	482	PF00069	0.693
MOD_GSK3_1	540	547	PF00069	0.666
MOD_GSK3_1	551	558	PF00069	0.610
MOD_GSK3_1	569	576	PF00069	0.598
MOD_GSK3_1	612	619	PF00069	0.618
MOD_GSK3_1	623	630	PF00069	0.591
MOD_GSK3_1	65	72	PF00069	0.702
MOD_GSK3_1	840	847	PF00069	0.547
MOD_LATS_1	384	390	PF00433	0.578
MOD_N-GLC_1	669	674	PF02516	0.697
MOD_N-GLC_1	771	776	PF02516	0.385
MOD_N-GLC_1	835	840	PF02516	0.653
MOD_NEK2_1	10	15	PF00069	0.359
MOD_NEK2_1	157	162	PF00069	0.533
MOD_NEK2_1	357	362	PF00069	0.556
MOD_NEK2_1	397	402	PF00069	0.591
MOD_NEK2_1	414	419	PF00069	0.503
MOD_NEK2_1	601	606	PF00069	0.692
MOD_NEK2_1	79	84	PF00069	0.465
MOD_NEK2_1	95	100	PF00069	0.576
MOD_NEK2_2	377	382	PF00069	0.574
MOD_NEK2_2	406	411	PF00069	0.556
MOD_PIKK_1	171	177	PF00454	0.631
MOD_PIKK_1	226	232	PF00454	0.669
MOD_PIKK_1	421	427	PF00454	0.617
MOD_PIKK_1	525	531	PF00454	0.612
MOD_PK_1	475	481	PF00069	0.638
MOD_PKA_1	443	449	PF00069	0.658
MOD_PKA_1	662	668	PF00069	0.543
MOD_PKA_2	167	173	PF00069	0.548
MOD_PKA_2	231	237	PF00069	0.666
MOD_PKA_2	28	34	PF00069	0.511
MOD_PKA_2	313	319	PF00069	0.657
MOD_PKA_2	385	391	PF00069	0.574
MOD_PKA_2	406	412	PF00069	0.676
MOD_PKA_2	444	450	PF00069	0.630
MOD_PKA_2	46	52	PF00069	0.515
MOD_PKA_2	474	480	PF00069	0.647
MOD_PKA_2	493	499	PF00069	0.523
MOD_PKA_2	66	72	PF00069	0.664
MOD_PKA_2	662	668	PF00069	0.543
MOD_PKA_2	788	794	PF00069	0.331
MOD_PKB_1	27	35	PF00069	0.463
MOD_PKB_1	502	510	PF00069	0.567
MOD_Plk_1	377	383	PF00069	0.574
MOD_Plk_1	475	481	PF00069	0.638
MOD_Plk_1	669	675	PF00069	0.620
MOD_Plk_1	771	777	PF00069	0.385
MOD_Plk_2-3	623	629	PF00069	0.551
MOD_Plk_4	120	126	PF00069	0.673
MOD_Plk_4	327	333	PF00069	0.550
MOD_Plk_4	451	457	PF00069	0.559
MOD_Plk_4	655	661	PF00069	0.550
MOD_Plk_4	814	820	PF00069	0.553
MOD_Plk_4	84	90	PF00069	0.399
MOD_ProDKin_1	129	135	PF00069	0.556
MOD_ProDKin_1	194	200	PF00069	0.537
MOD_ProDKin_1	244	250	PF00069	0.692
MOD_ProDKin_1	280	286	PF00069	0.657
MOD_ProDKin_1	297	303	PF00069	0.647
MOD_ProDKin_1	316	322	PF00069	0.533
MOD_ProDKin_1	323	329	PF00069	0.678
MOD_ProDKin_1	352	358	PF00069	0.710
MOD_ProDKin_1	388	394	PF00069	0.664
MOD_ProDKin_1	427	433	PF00069	0.593
MOD_ProDKin_1	455	461	PF00069	0.588
MOD_ProDKin_1	467	473	PF00069	0.656
MOD_ProDKin_1	482	488	PF00069	0.556
MOD_ProDKin_1	523	529	PF00069	0.703
MOD_ProDKin_1	540	546	PF00069	0.521
MOD_ProDKin_1	548	554	PF00069	0.582
MOD_ProDKin_1	555	561	PF00069	0.526
MOD_ProDKin_1	580	586	PF00069	0.644
MOD_ProDKin_1	609	615	PF00069	0.696
MOD_ProDKin_1	618	624	PF00069	0.607
MOD_ProDKin_1	632	638	PF00069	0.591
MOD_ProDKin_1	648	654	PF00069	0.549
MOD_ProDKin_1	663	669	PF00069	0.542
MOD_ProDKin_1	724	730	PF00069	0.576
MOD_ProDKin_1	835	841	PF00069	0.677
MOD_ProDKin_1	848	854	PF00069	0.561
TRG_DiLeu_BaLyEn_6	822	827	PF01217	0.516
TRG_ENDOCYTIC_2	124	127	PF00928	0.533
TRG_ENDOCYTIC_2	761	764	PF00928	0.385
TRG_ER_diArg_1	146	149	PF00400	0.685
TRG_ER_diArg_1	312	315	PF00400	0.588
TRG_ER_diArg_1	4	6	PF00400	0.362
TRG_ER_diArg_1	442	445	PF00400	0.658
TRG_ER_diArg_1	662	664	PF00400	0.558
TRG_ER_diArg_1	689	691	PF00400	0.689
TRG_ER_diArg_1	699	702	PF00400	0.622
TRG_NES_CRM1_1	745	759	PF08389	0.522
TRG_NES_CRM1_1	86	101	PF08389	0.462
TRG_NES_CRM1_1	9	23	PF08389	0.402
TRG_NLS_MonoExtC_3	785	790	PF00514	0.309
TRG_NLS_MonoExtN_4	440	447	PF00514	0.587
TRG_NLS_MonoExtN_4	783	790	PF00514	0.331

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IJ04	Leishmania donovani	63%	100%
A4HWW7	Leishmania infantum	62%	100%
E9AQM9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	62%	100%
Q4QEU9	Leishmania major	60%	98%