Argininosuccinate synthase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

carbamoyl-phosphate synthase, putative

Species:

Leishmania braziliensis

UniProt:

A4H8I3_LEIBR

TriTrypDb:

LbrM.16.0600 , LBRM2903_160012300

Length:

1867

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4H8I3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006082	organic acid metabolic process	3	10
GO:0006139	nucleobase-containing compound metabolic process	3	10
GO:0006206	pyrimidine nucleobase metabolic process	5	10
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	7	10
GO:0006520	amino acid metabolic process	3	10
GO:0006525	arginine metabolic process	6	10
GO:0006526	arginine biosynthetic process	7	10
GO:0006541	glutamine metabolic process	6	10
GO:0006725	cellular aromatic compound metabolic process	3	10
GO:0006807	nitrogen compound metabolic process	2	10
GO:0008152	metabolic process	1	10
GO:0008652	amino acid biosynthetic process	4	10
GO:0009058	biosynthetic process	2	10
GO:0009064	glutamine family amino acid metabolic process	5	10
GO:0009084	glutamine family amino acid biosynthetic process	6	10
GO:0009112	nucleobase metabolic process	4	10
GO:0009987	cellular process	1	10
GO:0016053	organic acid biosynthetic process	4	10
GO:0018130	heterocycle biosynthetic process	4	10
GO:0019752	carboxylic acid metabolic process	5	10
GO:0019856	pyrimidine nucleobase biosynthetic process	6	10
GO:0034641	cellular nitrogen compound metabolic process	3	10
GO:0043436	oxoacid metabolic process	4	10
GO:0044237	cellular metabolic process	2	10
GO:0044238	primary metabolic process	2	10
GO:0044249	cellular biosynthetic process	3	10
GO:0044271	cellular nitrogen compound biosynthetic process	4	10
GO:0044281	small molecule metabolic process	2	10
GO:0044283	small molecule biosynthetic process	3	10
GO:0046112	nucleobase biosynthetic process	5	10
GO:0046394	carboxylic acid biosynthetic process	5	10
GO:0046483	heterocycle metabolic process	3	10
GO:0055086	nucleobase-containing small molecule metabolic process	3	10
GO:0071704	organic substance metabolic process	2	10
GO:0072527	pyrimidine-containing compound metabolic process	4	10
GO:0072528	pyrimidine-containing compound biosynthetic process	5	10
GO:1901360	organic cyclic compound metabolic process	3	10
GO:1901362	organic cyclic compound biosynthetic process	4	10
GO:1901564	organonitrogen compound metabolic process	3	10
GO:1901566	organonitrogen compound biosynthetic process	4	10
GO:1901576	organic substance biosynthetic process	3	10
GO:1901605	alpha-amino acid metabolic process	4	10
GO:1901607	alpha-amino acid biosynthetic process	5	10

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	10
GO:0003824	catalytic activity	1	10
GO:0004055	argininosuccinate synthase activity	4	10
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	5	10
GO:0005488	binding	1	10
GO:0005524	ATP binding	5	10
GO:0016874	ligase activity	2	10
GO:0016879	ligase activity, forming carbon-nitrogen bonds	3	10
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	4	10
GO:0017076	purine nucleotide binding	4	10
GO:0030554	adenyl nucleotide binding	5	10
GO:0032553	ribonucleotide binding	3	10
GO:0032555	purine ribonucleotide binding	4	10
GO:0032559	adenyl ribonucleotide binding	5	10
GO:0035639	purine ribonucleoside triphosphate binding	4	10
GO:0036094	small molecule binding	2	10
GO:0043167	ion binding	2	10
GO:0043168	anion binding	3	10
GO:0043169	cation binding	3	10
GO:0046872	metal ion binding	4	10
GO:0097159	organic cyclic compound binding	2	10
GO:0097367	carbohydrate derivative binding	2	10
GO:1901265	nucleoside phosphate binding	3	10
GO:1901363	heterocyclic compound binding	2	10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1336	1340	PF00656	0.374
CLV_C14_Caspase3-7	1389	1393	PF00656	0.457
CLV_C14_Caspase3-7	1533	1537	PF00656	0.363
CLV_C14_Caspase3-7	471	475	PF00656	0.372
CLV_MEL_PAP_1	797	803	PF00089	0.200
CLV_NRD_NRD_1	1259	1261	PF00675	0.405
CLV_NRD_NRD_1	1354	1356	PF00675	0.343
CLV_NRD_NRD_1	140	142	PF00675	0.284
CLV_NRD_NRD_1	1425	1427	PF00675	0.242
CLV_NRD_NRD_1	1439	1441	PF00675	0.145
CLV_NRD_NRD_1	1495	1497	PF00675	0.301
CLV_NRD_NRD_1	1652	1654	PF00675	0.261
CLV_NRD_NRD_1	1839	1841	PF00675	0.595
CLV_NRD_NRD_1	382	384	PF00675	0.407
CLV_NRD_NRD_1	397	399	PF00675	0.332
CLV_NRD_NRD_1	813	815	PF00675	0.163
CLV_NRD_NRD_1	903	905	PF00675	0.349
CLV_NRD_NRD_1	977	979	PF00675	0.314
CLV_PCSK_FUR_1	901	905	PF00082	0.343
CLV_PCSK_KEX2_1	1194	1196	PF00082	0.260
CLV_PCSK_KEX2_1	1269	1271	PF00082	0.377
CLV_PCSK_KEX2_1	1354	1356	PF00082	0.343
CLV_PCSK_KEX2_1	1419	1421	PF00082	0.266
CLV_PCSK_KEX2_1	1425	1427	PF00082	0.280
CLV_PCSK_KEX2_1	1439	1441	PF00082	0.208
CLV_PCSK_KEX2_1	1495	1497	PF00082	0.301
CLV_PCSK_KEX2_1	1839	1841	PF00082	0.511
CLV_PCSK_KEX2_1	382	384	PF00082	0.372
CLV_PCSK_KEX2_1	813	815	PF00082	0.337
CLV_PCSK_KEX2_1	903	905	PF00082	0.342
CLV_PCSK_KEX2_1	977	979	PF00082	0.314
CLV_PCSK_PC1ET2_1	1194	1196	PF00082	0.260
CLV_PCSK_PC1ET2_1	1269	1271	PF00082	0.401
CLV_PCSK_PC1ET2_1	1419	1421	PF00082	0.255
CLV_PCSK_SKI1_1	1123	1127	PF00082	0.260
CLV_PCSK_SKI1_1	1269	1273	PF00082	0.368
CLV_PCSK_SKI1_1	1318	1322	PF00082	0.329
CLV_PCSK_SKI1_1	1330	1334	PF00082	0.370
CLV_PCSK_SKI1_1	1355	1359	PF00082	0.338
CLV_PCSK_SKI1_1	1806	1810	PF00082	0.260
CLV_PCSK_SKI1_1	219	223	PF00082	0.243
CLV_PCSK_SKI1_1	265	269	PF00082	0.243
CLV_PCSK_SKI1_1	272	276	PF00082	0.243
CLV_PCSK_SKI1_1	382	386	PF00082	0.337
CLV_PCSK_SKI1_1	398	402	PF00082	0.353
CLV_PCSK_SKI1_1	519	523	PF00082	0.243
CLV_PCSK_SKI1_1	712	716	PF00082	0.243
CLV_PCSK_SKI1_1	717	721	PF00082	0.243
CLV_PCSK_SKI1_1	825	829	PF00082	0.312
CLV_PCSK_SKI1_1	844	848	PF00082	0.153
CLV_PCSK_SKI1_1	982	986	PF00082	0.356
CLV_Separin_Metazoa	607	611	PF03568	0.443
CLV_Separin_Metazoa	870	874	PF03568	0.543
DEG_APCC_DBOX_1	522	530	PF00400	0.443
DEG_APCC_DBOX_1	843	851	PF00400	0.514
DEG_APCC_DBOX_1	872	880	PF00400	0.494
DEG_APCC_DBOX_1	903	911	PF00400	0.484
DEG_Nend_Nbox_1	1	3	PF02207	0.392
DOC_AGCK_PIF_1	42	47	PF00069	0.460
DOC_CKS1_1	506	511	PF01111	0.360
DOC_CYCLIN_RxL_1	214	225	PF00134	0.483
DOC_CYCLIN_RxL_1	712	721	PF00134	0.443
DOC_CYCLIN_RxL_1	819	832	PF00134	0.543
DOC_CYCLIN_yCln2_LP_2	1545	1551	PF00134	0.483
DOC_CYCLIN_yCln2_LP_2	506	512	PF00134	0.438
DOC_MAPK_gen_1	1019	1027	PF00069	0.317
DOC_MAPK_gen_1	1064	1074	PF00069	0.443
DOC_MAPK_gen_1	1260	1268	PF00069	0.452
DOC_MAPK_gen_1	1310	1317	PF00069	0.344
DOC_MAPK_gen_1	1351	1359	PF00069	0.363
DOC_MAPK_gen_1	1405	1415	PF00069	0.463
DOC_MAPK_gen_1	141	151	PF00069	0.443
DOC_MAPK_gen_1	1495	1503	PF00069	0.368
DOC_MAPK_gen_1	353	362	PF00069	0.443
DOC_MAPK_gen_1	394	403	PF00069	0.392
DOC_MAPK_gen_1	470	478	PF00069	0.374
DOC_MAPK_gen_1	499	505	PF00069	0.318
DOC_MAPK_gen_1	579	586	PF00069	0.460
DOC_MAPK_gen_1	901	909	PF00069	0.343
DOC_MAPK_gen_1	977	985	PF00069	0.338
DOC_MAPK_HePTP_8	1403	1415	PF00069	0.460
DOC_MAPK_MEF2A_6	1021	1029	PF00069	0.314
DOC_MAPK_MEF2A_6	1406	1415	PF00069	0.443
DOC_MAPK_MEF2A_6	1495	1503	PF00069	0.368
DOC_MAPK_MEF2A_6	223	230	PF00069	0.443
DOC_MAPK_MEF2A_6	579	586	PF00069	0.444
DOC_MAPK_MEF2A_6	901	909	PF00069	0.372
DOC_PP1_RVXF_1	1000	1006	PF00149	0.385
DOC_PP1_RVXF_1	1328	1335	PF00149	0.433
DOC_PP1_RVXF_1	1579	1585	PF00149	0.514
DOC_PP1_RVXF_1	260	267	PF00149	0.514
DOC_PP1_RVXF_1	548	555	PF00149	0.514
DOC_PP1_SILK_1	495	500	PF00149	0.312
DOC_PP2B_LxvP_1	1072	1075	PF13499	0.421
DOC_PP2B_LxvP_1	1545	1548	PF13499	0.483
DOC_PP2B_LxvP_1	1684	1687	PF13499	0.514
DOC_PP2B_LxvP_1	2	5	PF13499	0.400
DOC_PP4_FxxP_1	1182	1185	PF00568	0.460
DOC_PP4_FxxP_1	1325	1328	PF00568	0.305
DOC_PP4_FxxP_1	1749	1752	PF00568	0.439
DOC_PP4_FxxP_1	179	182	PF00568	0.407
DOC_PP4_FxxP_1	795	798	PF00568	0.318
DOC_USP7_MATH_1	1239	1243	PF00917	0.443
DOC_USP7_MATH_1	1390	1394	PF00917	0.474
DOC_USP7_MATH_1	1541	1545	PF00917	0.543
DOC_USP7_MATH_1	1604	1608	PF00917	0.443
DOC_USP7_MATH_1	1685	1689	PF00917	0.543
DOC_USP7_MATH_1	189	193	PF00917	0.491
DOC_USP7_MATH_1	288	292	PF00917	0.430
DOC_USP7_MATH_1	356	360	PF00917	0.483
DOC_USP7_MATH_1	538	542	PF00917	0.443
DOC_USP7_MATH_1	696	700	PF00917	0.443
DOC_USP7_UBL2_3	1190	1194	PF12436	0.443
DOC_USP7_UBL2_3	1326	1330	PF12436	0.414
DOC_USP7_UBL2_3	1481	1485	PF12436	0.483
DOC_USP7_UBL2_3	1608	1612	PF12436	0.514
DOC_USP7_UBL2_3	1654	1658	PF12436	0.483
DOC_USP7_UBL2_3	390	394	PF12436	0.380
DOC_WW_Pin1_4	1430	1435	PF00397	0.397
DOC_WW_Pin1_4	1696	1701	PF00397	0.462
DOC_WW_Pin1_4	1718	1723	PF00397	0.460
DOC_WW_Pin1_4	505	510	PF00397	0.355
DOC_WW_Pin1_4	586	591	PF00397	0.460
DOC_WW_Pin1_4	81	86	PF00397	0.483
DOC_WW_Pin1_4	813	818	PF00397	0.443
LIG_14-3-3_CanoR_1	1233	1239	PF00244	0.443
LIG_14-3-3_CanoR_1	1515	1523	PF00244	0.396
LIG_14-3-3_CanoR_1	1598	1603	PF00244	0.461
LIG_14-3-3_CanoR_1	1806	1816	PF00244	0.483
LIG_14-3-3_CanoR_1	196	204	PF00244	0.414
LIG_14-3-3_CanoR_1	313	323	PF00244	0.483
LIG_14-3-3_CanoR_1	958	964	PF00244	0.310
LIG_Actin_WH2_2	1026	1044	PF00022	0.442
LIG_Actin_WH2_2	1211	1228	PF00022	0.443
LIG_Actin_WH2_2	1813	1831	PF00022	0.460
LIG_AP2alpha_2	676	678	PF02296	0.543
LIG_APCC_ABBA_1	1396	1401	PF00400	0.543
LIG_APCC_ABBA_1	1456	1461	PF00400	0.329
LIG_BIR_III_2	1719	1723	PF00653	0.363
LIG_BRCT_BRCA1_1	1236	1240	PF00533	0.443
LIG_BRCT_BRCA1_1	1703	1707	PF00533	0.465
LIG_BRCT_BRCA1_1	1759	1763	PF00533	0.363
LIG_BRCT_BRCA1_1	358	362	PF00533	0.483
LIG_BRCT_BRCA1_1	961	965	PF00533	0.312
LIG_Clathr_ClatBox_1	1218	1222	PF01394	0.363
LIG_CtBP_PxDLS_1	67	71	PF00389	0.460
LIG_deltaCOP1_diTrp_1	333	339	PF00928	0.441
LIG_deltaCOP1_diTrp_1	348	357	PF00928	0.447
LIG_EH1_1	1496	1504	PF00400	0.466
LIG_EH1_1	223	231	PF00400	0.543
LIG_eIF4E_1	75	81	PF01652	0.460
LIG_eIF4E_1	848	854	PF01652	0.543
LIG_FHA_1	1120	1126	PF00498	0.500
LIG_FHA_1	1178	1184	PF00498	0.443
LIG_FHA_1	12	18	PF00498	0.679
LIG_FHA_1	1242	1248	PF00498	0.443
LIG_FHA_1	1300	1306	PF00498	0.359
LIG_FHA_1	1340	1346	PF00498	0.367
LIG_FHA_1	1363	1369	PF00498	0.451
LIG_FHA_1	151	157	PF00498	0.443
LIG_FHA_1	1719	1725	PF00498	0.514
LIG_FHA_1	1807	1813	PF00498	0.460
LIG_FHA_1	182	188	PF00498	0.437
LIG_FHA_1	201	207	PF00498	0.371
LIG_FHA_1	225	231	PF00498	0.443
LIG_FHA_1	236	242	PF00498	0.443
LIG_FHA_1	327	333	PF00498	0.363
LIG_FHA_1	371	377	PF00498	0.443
LIG_FHA_1	432	438	PF00498	0.414
LIG_FHA_1	59	65	PF00498	0.443
LIG_FHA_1	858	864	PF00498	0.546
LIG_FHA_2	1010	1016	PF00498	0.357
LIG_FHA_2	1186	1192	PF00498	0.429
LIG_FHA_2	1642	1648	PF00498	0.493
LIG_FHA_2	1845	1851	PF00498	0.468
LIG_FHA_2	444	450	PF00498	0.387
LIG_FHA_2	538	544	PF00498	0.433
LIG_FHA_2	774	780	PF00498	0.345
LIG_FHA_2	894	900	PF00498	0.371
LIG_FHA_2	993	999	PF00498	0.377
LIG_HCF-1_HBM_1	452	455	PF13415	0.426
LIG_IRF3_LxIS_1	1241	1248	PF10401	0.443
LIG_LIR_Apic_2	1180	1185	PF02991	0.460
LIG_LIR_Apic_2	1444	1448	PF02991	0.514
LIG_LIR_Apic_2	176	182	PF02991	0.404
LIG_LIR_Apic_2	452	458	PF02991	0.362
LIG_LIR_Apic_2	793	798	PF02991	0.420
LIG_LIR_Gen_1	1063	1072	PF02991	0.363
LIG_LIR_Gen_1	1284	1293	PF02991	0.322
LIG_LIR_Gen_1	1407	1415	PF02991	0.439
LIG_LIR_Gen_1	1539	1549	PF02991	0.514
LIG_LIR_Gen_1	1561	1571	PF02991	0.445
LIG_LIR_Gen_1	1640	1649	PF02991	0.543
LIG_LIR_Gen_1	1699	1710	PF02991	0.460
LIG_LIR_Gen_1	1824	1833	PF02991	0.499
LIG_LIR_Gen_1	354	364	PF02991	0.443
LIG_LIR_Gen_1	603	613	PF02991	0.443
LIG_LIR_Gen_1	647	657	PF02991	0.443
LIG_LIR_Gen_1	679	689	PF02991	0.443
LIG_LIR_Gen_1	737	746	PF02991	0.318
LIG_LIR_Gen_1	751	760	PF02991	0.338
LIG_LIR_Gen_1	805	812	PF02991	0.353
LIG_LIR_Gen_1	946	957	PF02991	0.312
LIG_LIR_Nem_3	1094	1100	PF02991	0.516
LIG_LIR_Nem_3	1248	1252	PF02991	0.452
LIG_LIR_Nem_3	1284	1288	PF02991	0.315
LIG_LIR_Nem_3	1371	1375	PF02991	0.363
LIG_LIR_Nem_3	1407	1412	PF02991	0.439
LIG_LIR_Nem_3	1473	1478	PF02991	0.357
LIG_LIR_Nem_3	1524	1529	PF02991	0.507
LIG_LIR_Nem_3	1539	1545	PF02991	0.371
LIG_LIR_Nem_3	1561	1566	PF02991	0.445
LIG_LIR_Nem_3	1583	1587	PF02991	0.497
LIG_LIR_Nem_3	1640	1645	PF02991	0.543
LIG_LIR_Nem_3	1699	1705	PF02991	0.460
LIG_LIR_Nem_3	1775	1780	PF02991	0.461
LIG_LIR_Nem_3	1824	1830	PF02991	0.514
LIG_LIR_Nem_3	1861	1865	PF02991	0.403
LIG_LIR_Nem_3	239	245	PF02991	0.445
LIG_LIR_Nem_3	326	330	PF02991	0.448
LIG_LIR_Nem_3	333	338	PF02991	0.435
LIG_LIR_Nem_3	354	360	PF02991	0.453
LIG_LIR_Nem_3	374	380	PF02991	0.307
LIG_LIR_Nem_3	40	45	PF02991	0.443
LIG_LIR_Nem_3	603	609	PF02991	0.443
LIG_LIR_Nem_3	647	652	PF02991	0.443
LIG_LIR_Nem_3	679	685	PF02991	0.443
LIG_LIR_Nem_3	737	743	PF02991	0.320
LIG_LIR_Nem_3	751	756	PF02991	0.334
LIG_LIR_Nem_3	789	795	PF02991	0.428
LIG_LIR_Nem_3	816	821	PF02991	0.488
LIG_LIR_Nem_3	843	848	PF02991	0.514
LIG_LIR_Nem_3	946	952	PF02991	0.316
LIG_LIR_Nem_3	964	970	PF02991	0.236
LIG_LYPXL_yS_3	1097	1100	PF13949	0.514
LIG_NRBOX	1688	1694	PF00104	0.363
LIG_NRBOX	217	223	PF00104	0.443
LIG_PCNA_PIPBox_1	839	848	PF02747	0.542
LIG_Pex14_1	335	339	PF04695	0.443
LIG_Pex14_2	1538	1542	PF04695	0.483
LIG_Pex14_2	323	327	PF04695	0.443
LIG_PTB_Apo_2	1557	1564	PF02174	0.474
LIG_PTB_Apo_2	643	650	PF02174	0.443
LIG_Rb_pABgroove_1	1759	1767	PF01858	0.460
LIG_REV1ctd_RIR_1	843	853	PF16727	0.443
LIG_SH2_CRK	1197	1201	PF00017	0.543
LIG_SH2_CRK	1372	1376	PF00017	0.439
LIG_SH2_CRK	1445	1449	PF00017	0.486
LIG_SH2_CRK	242	246	PF00017	0.443
LIG_SH2_CRK	90	94	PF00017	0.443
LIG_SH2_CRK	949	953	PF00017	0.316
LIG_SH2_CRK	967	971	PF00017	0.335
LIG_SH2_GRB2like	613	616	PF00017	0.460
LIG_SH2_GRB2like	864	867	PF00017	0.543
LIG_SH2_NCK_1	1197	1201	PF00017	0.460
LIG_SH2_PTP2	682	685	PF00017	0.443
LIG_SH2_PTP2	740	743	PF00017	0.317
LIG_SH2_SRC	1590	1593	PF00017	0.543
LIG_SH2_SRC	49	52	PF00017	0.483
LIG_SH2_SRC	930	933	PF00017	0.474
LIG_SH2_STAP1	1149	1153	PF00017	0.453
LIG_SH2_STAP1	1399	1403	PF00017	0.461
LIG_SH2_STAP1	1765	1769	PF00017	0.460
LIG_SH2_STAP1	1780	1784	PF00017	0.460
LIG_SH2_STAP1	49	53	PF00017	0.443
LIG_SH2_STAP1	613	617	PF00017	0.460
LIG_SH2_STAP1	864	868	PF00017	0.507
LIG_SH2_STAT3	123	126	PF00017	0.514
LIG_SH2_STAT3	501	504	PF00017	0.342
LIG_SH2_STAT3	75	78	PF00017	0.460
LIG_SH2_STAT3	935	938	PF00017	0.356
LIG_SH2_STAT5	1004	1007	PF00017	0.360
LIG_SH2_STAT5	105	108	PF00017	0.478
LIG_SH2_STAT5	1105	1108	PF00017	0.442
LIG_SH2_STAT5	1124	1127	PF00017	0.348
LIG_SH2_STAT5	123	126	PF00017	0.351
LIG_SH2_STAT5	1348	1351	PF00017	0.460
LIG_SH2_STAT5	1360	1363	PF00017	0.460
LIG_SH2_STAT5	1478	1481	PF00017	0.351
LIG_SH2_STAT5	1529	1532	PF00017	0.514
LIG_SH2_STAT5	1585	1588	PF00017	0.523
LIG_SH2_STAT5	1590	1593	PF00017	0.502
LIG_SH2_STAT5	1677	1680	PF00017	0.439
LIG_SH2_STAT5	338	341	PF00017	0.460
LIG_SH2_STAT5	375	378	PF00017	0.447
LIG_SH2_STAT5	380	383	PF00017	0.491
LIG_SH2_STAT5	455	458	PF00017	0.353
LIG_SH2_STAT5	562	565	PF00017	0.460
LIG_SH2_STAT5	682	685	PF00017	0.443
LIG_SH2_STAT5	740	743	PF00017	0.317
LIG_SH2_STAT5	792	795	PF00017	0.425
LIG_SH2_STAT5	875	878	PF00017	0.504
LIG_SH2_STAT5	930	933	PF00017	0.333
LIG_SH3_3	1071	1077	PF00018	0.443
LIG_SH3_3	1092	1098	PF00018	0.443
LIG_SH3_3	1206	1212	PF00018	0.443
LIG_SH3_3	1341	1347	PF00018	0.214
LIG_SH3_3	1830	1836	PF00018	0.392
LIG_SH3_3	1851	1857	PF00018	0.455
LIG_SH3_3	248	254	PF00018	0.443
LIG_SH3_3	61	67	PF00018	0.443
LIG_SH3_3	634	640	PF00018	0.443
LIG_SH3_3	740	746	PF00018	0.315
LIG_SH3_3	809	815	PF00018	0.207
LIG_SH3_5	736	740	PF00018	0.327
LIG_SUMO_SIM_anti_2	1009	1018	PF11976	0.380
LIG_SUMO_SIM_anti_2	1150	1155	PF11976	0.443
LIG_SUMO_SIM_anti_2	1205	1211	PF11976	0.437
LIG_SUMO_SIM_anti_2	225	230	PF11976	0.444
LIG_SUMO_SIM_anti_2	508	514	PF11976	0.446
LIG_SUMO_SIM_par_1	1009	1018	PF11976	0.497
LIG_SUMO_SIM_par_1	1134	1140	PF11976	0.443
LIG_SUMO_SIM_par_1	1547	1553	PF11976	0.443
LIG_SUMO_SIM_par_1	1755	1760	PF11976	0.363
LIG_SUMO_SIM_par_1	1813	1819	PF11976	0.449
LIG_SUMO_SIM_par_1	205	210	PF11976	0.353
LIG_SUMO_SIM_par_1	457	462	PF11976	0.438
LIG_SUMO_SIM_par_1	511	518	PF11976	0.351
LIG_SUMO_SIM_par_1	78	84	PF11976	0.460
LIG_SxIP_EBH_1	864	873	PF03271	0.363
LIG_TRAF2_1	1847	1850	PF00917	0.499
LIG_TRAF2_1	541	544	PF00917	0.483
LIG_TRAF2_1	776	779	PF00917	0.328
LIG_TRAF2_1	832	835	PF00917	0.491
LIG_TRAF2_1	94	97	PF00917	0.439
LIG_TRAF2_2	1184	1189	PF00917	0.460
LIG_TRFH_1	673	677	PF08558	0.297
LIG_TYR_ITIM	1095	1100	PF00017	0.396
LIG_TYR_ITIM	604	609	PF00017	0.297
LIG_UBA3_1	1825	1829	PF00899	0.353
LIG_UBA3_1	206	214	PF00899	0.298
LIG_UBA3_1	719	728	PF00899	0.277
LIG_UBA3_1	876	880	PF00899	0.317
LIG_WRC_WIRS_1	1282	1287	PF05994	0.319
MOD_CDK_SPxK_1	813	819	PF00069	0.297
MOD_CK1_1	1009	1015	PF00069	0.354
MOD_CK1_1	1063	1069	PF00069	0.435
MOD_CK1_1	1081	1087	PF00069	0.383
MOD_CK1_1	1129	1135	PF00069	0.280
MOD_CK1_1	1234	1240	PF00069	0.297
MOD_CK1_1	1281	1287	PF00069	0.345
MOD_CK1_1	1580	1586	PF00069	0.396
MOD_CK1_1	1810	1816	PF00069	0.438
MOD_CK1_1	192	198	PF00069	0.453
MOD_CK1_1	692	698	PF00069	0.297
MOD_CK1_1	699	705	PF00069	0.297
MOD_CK1_1	857	863	PF00069	0.399
MOD_CK2_1	1298	1304	PF00069	0.357
MOD_CK2_1	1337	1343	PF00069	0.421
MOD_CK2_1	1465	1471	PF00069	0.433
MOD_CK2_1	1567	1573	PF00069	0.396
MOD_CK2_1	1797	1803	PF00069	0.333
MOD_CK2_1	1844	1850	PF00069	0.471
MOD_CK2_1	423	429	PF00069	0.516
MOD_CK2_1	443	449	PF00069	0.204
MOD_CK2_1	537	543	PF00069	0.296
MOD_CK2_1	642	648	PF00069	0.297
MOD_CK2_1	763	769	PF00069	0.367
MOD_CK2_1	773	779	PF00069	0.327
MOD_CK2_1	829	835	PF00069	0.321
MOD_GlcNHglycan	1043	1046	PF01048	0.477
MOD_GlcNHglycan	1080	1083	PF01048	0.396
MOD_GlcNHglycan	1107	1110	PF01048	0.283
MOD_GlcNHglycan	1131	1134	PF01048	0.315
MOD_GlcNHglycan	115	118	PF01048	0.297
MOD_GlcNHglycan	1175	1178	PF01048	0.297
MOD_GlcNHglycan	1254	1257	PF01048	0.319
MOD_GlcNHglycan	1386	1389	PF01048	0.340
MOD_GlcNHglycan	1560	1563	PF01048	0.421
MOD_GlcNHglycan	1569	1572	PF01048	0.360
MOD_GlcNHglycan	1695	1699	PF01048	0.412
MOD_GlcNHglycan	1708	1711	PF01048	0.317
MOD_GlcNHglycan	1770	1774	PF01048	0.326
MOD_GlcNHglycan	1799	1802	PF01048	0.344
MOD_GlcNHglycan	1811	1815	PF01048	0.321
MOD_GlcNHglycan	417	421	PF01048	0.360
MOD_GlcNHglycan	535	538	PF01048	0.333
MOD_GlcNHglycan	568	571	PF01048	0.297
MOD_GlcNHglycan	653	656	PF01048	0.321
MOD_GlcNHglycan	694	697	PF01048	0.297
MOD_GlcNHglycan	801	804	PF01048	0.200
MOD_GlcNHglycan	831	834	PF01048	0.438
MOD_GSK3_1	1037	1044	PF00069	0.497
MOD_GSK3_1	1101	1108	PF00069	0.295
MOD_GSK3_1	1173	1180	PF00069	0.288
MOD_GSK3_1	1185	1192	PF00069	0.254
MOD_GSK3_1	1241	1248	PF00069	0.297
MOD_GSK3_1	1333	1340	PF00069	0.427
MOD_GSK3_1	1380	1387	PF00069	0.325
MOD_GSK3_1	1765	1772	PF00069	0.336
MOD_GSK3_1	1778	1785	PF00069	0.335
MOD_GSK3_1	1791	1798	PF00069	0.348
MOD_GSK3_1	1806	1813	PF00069	0.297
MOD_GSK3_1	256	263	PF00069	0.396
MOD_GSK3_1	339	346	PF00069	0.430
MOD_GSK3_1	533	540	PF00069	0.259
MOD_GSK3_1	638	645	PF00069	0.297
MOD_GSK3_1	692	699	PF00069	0.297
MOD_GSK3_1	759	766	PF00069	0.360
MOD_GSK3_1	769	776	PF00069	0.333
MOD_GSK3_1	854	861	PF00069	0.447
MOD_N-GLC_1	1506	1511	PF02516	0.400
MOD_N-GLC_1	1521	1526	PF02516	0.321
MOD_N-GLC_1	1858	1863	PF02516	0.413
MOD_N-GLC_2	1489	1491	PF02516	0.400
MOD_N-GLC_2	1622	1624	PF02516	0.185
MOD_NEK2_1	100	105	PF00069	0.107
MOD_NEK2_1	1037	1042	PF00069	0.491
MOD_NEK2_1	106	111	PF00069	0.297
MOD_NEK2_1	1091	1096	PF00069	0.362
MOD_NEK2_1	1107	1112	PF00069	0.197
MOD_NEK2_1	1245	1250	PF00069	0.297
MOD_NEK2_1	150	155	PF00069	0.382
MOD_NEK2_1	1501	1506	PF00069	0.378
MOD_NEK2_1	1521	1526	PF00069	0.107
MOD_NEK2_1	1757	1762	PF00069	0.326
MOD_NEK2_1	1769	1774	PF00069	0.207
MOD_NEK2_1	1828	1833	PF00069	0.388
MOD_NEK2_1	245	250	PF00069	0.297
MOD_NEK2_1	256	261	PF00069	0.297
MOD_NEK2_1	416	421	PF00069	0.357
MOD_NEK2_1	522	527	PF00069	0.438
MOD_NEK2_1	594	599	PF00069	0.297
MOD_NEK2_1	651	656	PF00069	0.297
MOD_NEK2_1	691	696	PF00069	0.297
MOD_NEK2_1	763	768	PF00069	0.380
MOD_NEK2_1	80	85	PF00069	0.297
MOD_NEK2_1	892	897	PF00069	0.491
MOD_NEK2_1	931	936	PF00069	0.332
MOD_NEK2_2	1177	1182	PF00069	0.321
MOD_NEK2_2	1278	1283	PF00069	0.350
MOD_NEK2_2	200	205	PF00069	0.435
MOD_NEK2_2	257	262	PF00069	0.396
MOD_NEK2_2	423	428	PF00069	0.476
MOD_NEK2_2	859	864	PF00069	0.438
MOD_PIKK_1	11	17	PF00454	0.452
MOD_PIKK_1	1337	1343	PF00454	0.463
MOD_PIKK_1	1514	1520	PF00454	0.432
MOD_PIKK_1	1782	1788	PF00454	0.367
MOD_PIKK_1	1795	1801	PF00454	0.250
MOD_PIKK_1	315	321	PF00454	0.297
MOD_PIKK_1	418	424	PF00454	0.372
MOD_PIKK_1	638	644	PF00454	0.297
MOD_PK_1	1598	1604	PF00069	0.438
MOD_PK_1	653	659	PF00069	0.321
MOD_PKA_1	1425	1431	PF00069	0.321
MOD_PKA_2	1101	1107	PF00069	0.297
MOD_PKA_2	1232	1238	PF00069	0.297
MOD_PKA_2	1425	1431	PF00069	0.321
MOD_PKA_2	1514	1520	PF00069	0.432
MOD_PKA_2	195	201	PF00069	0.426
MOD_PKA_2	522	528	PF00069	0.438
MOD_PKA_2	689	695	PF00069	0.297
MOD_PKA_2	799	805	PF00069	0.431
MOD_PKA_2	837	843	PF00069	0.325
MOD_PKB_1	1596	1604	PF00069	0.353
MOD_Plk_1	1009	1015	PF00069	0.354
MOD_Plk_1	1119	1125	PF00069	0.343
MOD_Plk_1	1126	1132	PF00069	0.295
MOD_Plk_1	1177	1183	PF00069	0.297
MOD_Plk_1	1521	1527	PF00069	0.353
MOD_Plk_1	1765	1771	PF00069	0.396
MOD_Plk_1	224	230	PF00069	0.297
MOD_Plk_1	49	55	PF00069	0.297
MOD_Plk_1	594	600	PF00069	0.297
MOD_Plk_2-3	1006	1012	PF00069	0.347
MOD_Plk_2-3	1641	1647	PF00069	0.396
MOD_Plk_4	1009	1015	PF00069	0.354
MOD_Plk_4	1101	1107	PF00069	0.312
MOD_Plk_4	1126	1132	PF00069	0.283
MOD_Plk_4	1177	1183	PF00069	0.297
MOD_Plk_4	1278	1284	PF00069	0.349
MOD_Plk_4	1451	1457	PF00069	0.429
MOD_Plk_4	1580	1586	PF00069	0.396
MOD_Plk_4	1598	1604	PF00069	0.150
MOD_Plk_4	1672	1678	PF00069	0.396
MOD_Plk_4	1685	1691	PF00069	0.396
MOD_Plk_4	224	230	PF00069	0.299
MOD_Plk_4	431	437	PF00069	0.382
MOD_Plk_4	508	514	PF00069	0.446
MOD_Plk_4	522	528	PF00069	0.396
MOD_Plk_4	632	638	PF00069	0.297
MOD_Plk_4	759	765	PF00069	0.348
MOD_Plk_4	859	865	PF00069	0.368
MOD_ProDKin_1	1430	1436	PF00069	0.232
MOD_ProDKin_1	1696	1702	PF00069	0.324
MOD_ProDKin_1	1718	1724	PF00069	0.321
MOD_ProDKin_1	505	511	PF00069	0.358
MOD_ProDKin_1	586	592	PF00069	0.321
MOD_ProDKin_1	81	87	PF00069	0.353
MOD_ProDKin_1	813	819	PF00069	0.297
MOD_SUMO_for_1	1404	1407	PF00179	0.377
MOD_SUMO_for_1	30	33	PF00179	0.562
TRG_DiLeu_BaEn_1	1407	1412	PF01217	0.326
TRG_DiLeu_BaEn_2	1802	1808	PF01217	0.355
TRG_DiLeu_BaLyEn_6	1445	1450	PF01217	0.396
TRG_DiLeu_BaLyEn_6	1719	1724	PF01217	0.396
TRG_DiLeu_BaLyEn_6	908	913	PF01217	0.439
TRG_ENDOCYTIC_2	1097	1100	PF00928	0.396
TRG_ENDOCYTIC_2	1197	1200	PF00928	0.438
TRG_ENDOCYTIC_2	1372	1375	PF00928	0.185
TRG_ENDOCYTIC_2	1483	1486	PF00928	0.341
TRG_ENDOCYTIC_2	242	245	PF00928	0.297
TRG_ENDOCYTIC_2	606	609	PF00928	0.297
TRG_ENDOCYTIC_2	682	685	PF00928	0.297
TRG_ENDOCYTIC_2	740	743	PF00928	0.317
TRG_ENDOCYTIC_2	792	795	PF00928	0.425
TRG_ENDOCYTIC_2	818	821	PF00928	0.367
TRG_ENDOCYTIC_2	949	952	PF00928	0.317
TRG_ENDOCYTIC_2	967	970	PF00928	0.334
TRG_ER_diArg_1	1353	1355	PF00400	0.438
TRG_ER_diArg_1	1424	1426	PF00400	0.317
TRG_ER_diArg_1	1438	1440	PF00400	0.257
TRG_ER_diArg_1	1494	1496	PF00400	0.293
TRG_ER_diArg_1	1595	1598	PF00400	0.396
TRG_ER_diArg_1	381	383	PF00400	0.256
TRG_ER_diArg_1	812	814	PF00400	0.185
TRG_ER_diArg_1	900	903	PF00400	0.341
TRG_ER_diArg_1	976	978	PF00400	0.312
TRG_NES_CRM1_1	1216	1229	PF08389	0.185
TRG_NES_CRM1_1	1543	1557	PF08389	0.436
TRG_NES_CRM1_1	162	176	PF08389	0.353
TRG_NES_CRM1_1	448	462	PF08389	0.359
TRG_NLS_MonoExtN_4	1267	1273	PF00514	0.396
TRG_Pf-PMV_PEXEL_1	1123	1127	PF00026	0.321
TRG_Pf-PMV_PEXEL_1	1439	1444	PF00026	0.297
TRG_Pf-PMV_PEXEL_1	1806	1811	PF00026	0.321
TRG_Pf-PMV_PEXEL_1	185	190	PF00026	0.451
TRG_Pf-PMV_PEXEL_1	205	210	PF00026	0.159
TRG_Pf-PMV_PEXEL_1	425	429	PF00026	0.396
TRG_Pf-PMV_PEXEL_1	519	524	PF00026	0.396
TRG_Pf-PMV_PEXEL_1	610	614	PF00026	0.297
TRG_Pf-PMV_PEXEL_1	717	721	PF00026	0.297
TRG_Pf-PMV_PEXEL_1	825	829	PF00026	0.353
TRG_Pf-PMV_PEXEL_1	887	891	PF00026	0.396

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I157	Leptomonas seymouri	86%	100%
A0A1X0NNV1	Trypanosomatidae	76%	100%
A0A3S5H6X3	Leishmania donovani	94%	100%
A0A422MVX7	Trypanosoma rangeli	74%	100%
A4HWV8	Leishmania infantum	94%	100%
B2RQC6	Mus musculus	49%	84%
C9ZPQ9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	100%
E9AQL8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
O93937	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	49%	82%
P05990	Drosophila melanogaster	50%	84%
P07259	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	49%	84%
P07756	Rattus norvegicus	48%	100%
P08955	Mesocricetus auratus	49%	84%
P20054	Dictyostelium discoideum	49%	84%
P27708	Homo sapiens	50%	84%
P31327	Homo sapiens	48%	100%
Q09794	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	48%	83%
Q18990	Caenorhabditis elegans	49%	85%
Q4QEW0	Leishmania major	94%	100%
Q8C196	Mus musculus	48%	100%
Q91293	Lithobates catesbeianus	48%	100%
Q91437	Squalus acanthias	49%	83%