XRN_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

XRN 5'-3' exonuclease N-terminus, putative

Species:

Leishmania braziliensis

UniProt:

A4H8G4_LEIBR

TriTrypDb:

LbrM.16.0400 , LBRM2903_160009500

Length:

993

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4H8G4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H8G4

Function

Biological processes
Term	Name	Level	Count
GO:0000956	nuclear-transcribed mRNA catabolic process	7	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006401	RNA catabolic process	5	1
GO:0006402	mRNA catabolic process	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009056	catabolic process	2	1
GO:0009057	macromolecule catabolic process	4	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0009987	cellular process	1	1
GO:0010468	regulation of gene expression	5	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0010629	negative regulation of gene expression	6	1
GO:0016070	RNA metabolic process	5	1
GO:0016071	mRNA metabolic process	6	1
GO:0019222	regulation of metabolic process	3	1
GO:0019439	aromatic compound catabolic process	4	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034655	nucleobase-containing compound catabolic process	4	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044248	cellular catabolic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044265	obsolete cellular macromolecule catabolic process	4	1
GO:0044270	cellular nitrogen compound catabolic process	4	1
GO:0046483	heterocycle metabolic process	3	1
GO:0046700	heterocycle catabolic process	4	1
GO:0048519	negative regulation of biological process	3	1
GO:0050789	regulation of biological process	2	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1901361	organic cyclic compound catabolic process	4	1
GO:1901575	organic substance catabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	9
GO:0003824	catalytic activity	1	9
GO:0004518	nuclease activity	4	9
GO:0004527	exonuclease activity	5	9
GO:0005488	binding	1	9
GO:0016787	hydrolase activity	2	9
GO:0016788	hydrolase activity, acting on ester bonds	3	9
GO:0097159	organic cyclic compound binding	2	9
GO:1901363	heterocyclic compound binding	2	9
GO:0003723	RNA binding	4	1
GO:0004532	RNA exonuclease activity	5	1
GO:0004534	5'-3' RNA exonuclease activity	7	1
GO:0004540	RNA nuclease activity	4	1
GO:0008409	5'-3' exonuclease activity	6	1
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	1
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	6	1
GO:0140098	catalytic activity, acting on RNA	3	1
GO:0140640	catalytic activity, acting on a nucleic acid	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	946	950	PF00656	0.543
CLV_NRD_NRD_1	173	175	PF00675	0.255
CLV_NRD_NRD_1	303	305	PF00675	0.570
CLV_NRD_NRD_1	34	36	PF00675	0.583
CLV_NRD_NRD_1	407	409	PF00675	0.451
CLV_NRD_NRD_1	598	600	PF00675	0.569
CLV_NRD_NRD_1	6	8	PF00675	0.375
CLV_NRD_NRD_1	674	676	PF00675	0.591
CLV_NRD_NRD_1	76	78	PF00675	0.657
CLV_NRD_NRD_1	766	768	PF00675	0.592
CLV_NRD_NRD_1	788	790	PF00675	0.558
CLV_NRD_NRD_1	792	794	PF00675	0.549
CLV_NRD_NRD_1	813	815	PF00675	0.709
CLV_NRD_NRD_1	904	906	PF00675	0.804
CLV_NRD_NRD_1	940	942	PF00675	0.782
CLV_NRD_NRD_1	965	967	PF00675	0.591
CLV_NRD_NRD_1	987	989	PF00675	0.686
CLV_PCSK_FUR_1	170	174	PF00082	0.254
CLV_PCSK_FUR_1	672	676	PF00082	0.591
CLV_PCSK_FUR_1	937	941	PF00082	0.634
CLV_PCSK_FUR_1	963	967	PF00082	0.581
CLV_PCSK_KEX2_1	172	174	PF00082	0.254
CLV_PCSK_KEX2_1	33	35	PF00082	0.576
CLV_PCSK_KEX2_1	407	409	PF00082	0.357
CLV_PCSK_KEX2_1	597	599	PF00082	0.500
CLV_PCSK_KEX2_1	674	676	PF00082	0.594
CLV_PCSK_KEX2_1	740	742	PF00082	0.515
CLV_PCSK_KEX2_1	75	77	PF00082	0.661
CLV_PCSK_KEX2_1	766	768	PF00082	0.403
CLV_PCSK_KEX2_1	788	790	PF00082	0.558
CLV_PCSK_KEX2_1	792	794	PF00082	0.549
CLV_PCSK_KEX2_1	885	887	PF00082	0.609
CLV_PCSK_KEX2_1	904	906	PF00082	0.481
CLV_PCSK_KEX2_1	937	939	PF00082	0.623
CLV_PCSK_KEX2_1	940	942	PF00082	0.634
CLV_PCSK_KEX2_1	962	964	PF00082	0.595
CLV_PCSK_KEX2_1	965	967	PF00082	0.585
CLV_PCSK_KEX2_1	987	989	PF00082	0.692
CLV_PCSK_PC1ET2_1	33	35	PF00082	0.554
CLV_PCSK_PC1ET2_1	740	742	PF00082	0.505
CLV_PCSK_PC1ET2_1	885	887	PF00082	0.684
CLV_PCSK_PC1ET2_1	904	906	PF00082	0.482
CLV_PCSK_PC1ET2_1	962	964	PF00082	0.562
CLV_PCSK_PC1ET2_1	987	989	PF00082	0.692
CLV_PCSK_PC7_1	71	77	PF00082	0.671
CLV_PCSK_PC7_1	788	794	PF00082	0.611
CLV_PCSK_SKI1_1	216	220	PF00082	0.279
CLV_PCSK_SKI1_1	357	361	PF00082	0.479
CLV_PCSK_SKI1_1	366	370	PF00082	0.575
CLV_PCSK_SKI1_1	562	566	PF00082	0.462
CLV_PCSK_SKI1_1	583	587	PF00082	0.415
CLV_PCSK_SKI1_1	625	629	PF00082	0.465
CLV_PCSK_SKI1_1	77	81	PF00082	0.687
CLV_PCSK_SKI1_1	806	810	PF00082	0.599
CLV_PCSK_SKI1_1	886	890	PF00082	0.624
CLV_PCSK_SKI1_1	898	902	PF00082	0.613
CLV_PCSK_SKI1_1	905	909	PF00082	0.668
DEG_SCF_FBW7_1	513	519	PF00400	0.323
DOC_ANK_TNKS_1	34	41	PF00023	0.619
DOC_CKS1_1	513	518	PF01111	0.347
DOC_CKS1_1	782	787	PF01111	0.594
DOC_MAPK_gen_1	170	178	PF00069	0.479
DOC_MAPK_gen_1	309	318	PF00069	0.429
DOC_MAPK_gen_1	562	570	PF00069	0.451
DOC_MAPK_gen_1	764	771	PF00069	0.482
DOC_MAPK_MEF2A_6	150	157	PF00069	0.487
DOC_MAPK_MEF2A_6	380	388	PF00069	0.346
DOC_MAPK_RevD_3	161	175	PF00069	0.521
DOC_PP1_RVXF_1	240	247	PF00149	0.504
DOC_PP1_RVXF_1	378	384	PF00149	0.302
DOC_PP1_SILK_1	545	550	PF00149	0.504
DOC_PP2B_LxvP_1	19	22	PF13499	0.463
DOC_PP2B_PxIxI_1	376	382	PF00149	0.372
DOC_PP4_FxxP_1	157	160	PF00568	0.521
DOC_PP4_FxxP_1	585	588	PF00568	0.403
DOC_PP4_FxxP_1	649	652	PF00568	0.388
DOC_PP4_FxxP_1	782	785	PF00568	0.593
DOC_SPAK_OSR1_1	35	39	PF12202	0.443
DOC_USP7_MATH_1	149	153	PF00917	0.456
DOC_USP7_MATH_1	248	252	PF00917	0.492
DOC_USP7_MATH_1	312	316	PF00917	0.384
DOC_USP7_MATH_1	847	851	PF00917	0.662
DOC_WW_Pin1_4	258	263	PF00397	0.685
DOC_WW_Pin1_4	339	344	PF00397	0.398
DOC_WW_Pin1_4	366	371	PF00397	0.530
DOC_WW_Pin1_4	420	425	PF00397	0.430
DOC_WW_Pin1_4	512	517	PF00397	0.354
DOC_WW_Pin1_4	584	589	PF00397	0.439
DOC_WW_Pin1_4	709	714	PF00397	0.651
DOC_WW_Pin1_4	781	786	PF00397	0.603
DOC_WW_Pin1_4	838	843	PF00397	0.579
DOC_WW_Pin1_4	97	102	PF00397	0.468
LIG_14-3-3_CanoR_1	140	149	PF00244	0.521
LIG_14-3-3_CanoR_1	150	154	PF00244	0.521
LIG_14-3-3_CanoR_1	173	179	PF00244	0.479
LIG_14-3-3_CanoR_1	350	358	PF00244	0.462
LIG_14-3-3_CanoR_1	407	413	PF00244	0.345
LIG_14-3-3_CanoR_1	497	505	PF00244	0.451
LIG_14-3-3_CanoR_1	583	588	PF00244	0.501
LIG_14-3-3_CanoR_1	625	630	PF00244	0.568
LIG_14-3-3_CanoR_1	693	702	PF00244	0.774
LIG_14-3-3_CanoR_1	76	85	PF00244	0.686
LIG_14-3-3_CanoR_1	766	770	PF00244	0.583
LIG_14-3-3_CanoR_1	886	895	PF00244	0.512
LIG_Actin_WH2_2	344	362	PF00022	0.463
LIG_Actin_WH2_2	790	808	PF00022	0.515
LIG_BIR_III_2	839	843	PF00653	0.572
LIG_BRCT_BRCA1_1	153	157	PF00533	0.521
LIG_BRCT_BRCA1_1	331	335	PF00533	0.231
LIG_Clathr_ClatBox_1	197	201	PF01394	0.454
LIG_eIF4E_1	416	422	PF01652	0.476
LIG_FHA_1	14	20	PF00498	0.419
LIG_FHA_1	142	148	PF00498	0.465
LIG_FHA_1	166	172	PF00498	0.493
LIG_FHA_1	179	185	PF00498	0.479
LIG_FHA_1	187	193	PF00498	0.562
LIG_FHA_1	555	561	PF00498	0.484
LIG_FHA_1	584	590	PF00498	0.401
LIG_FHA_1	642	648	PF00498	0.517
LIG_FHA_1	766	772	PF00498	0.510
LIG_FHA_1	930	936	PF00498	0.566
LIG_FHA_2	259	265	PF00498	0.758
LIG_FHA_2	513	519	PF00498	0.374
LIG_FHA_2	551	557	PF00498	0.497
LIG_FHA_2	574	580	PF00498	0.391
LIG_FHA_2	626	632	PF00498	0.535
LIG_FHA_2	643	649	PF00498	0.307
LIG_FHA_2	661	667	PF00498	0.492
LIG_FHA_2	850	856	PF00498	0.485
LIG_FHA_2	917	923	PF00498	0.634
LIG_FHA_2	944	950	PF00498	0.629
LIG_FHA_2	979	985	PF00498	0.603
LIG_Integrin_RGD_1	299	301	PF01839	0.494
LIG_LIR_Apic_2	154	160	PF02991	0.521
LIG_LIR_Apic_2	648	652	PF02991	0.371
LIG_LIR_Gen_1	332	343	PF02991	0.320
LIG_LIR_Gen_1	382	389	PF02991	0.303
LIG_LIR_Gen_1	473	482	PF02991	0.459
LIG_LIR_Gen_1	518	528	PF02991	0.407
LIG_LIR_Gen_1	644	653	PF02991	0.506
LIG_LIR_Nem_3	332	338	PF02991	0.314
LIG_LIR_Nem_3	353	359	PF02991	0.261
LIG_LIR_Nem_3	382	388	PF02991	0.308
LIG_LIR_Nem_3	39	44	PF02991	0.615
LIG_LIR_Nem_3	473	477	PF02991	0.395
LIG_LIR_Nem_3	518	523	PF02991	0.424
LIG_LIR_Nem_3	644	649	PF02991	0.479
LIG_LIR_Nem_3	955	961	PF02991	0.503
LIG_Pex14_2	383	387	PF04695	0.302
LIG_RPA_C_Fungi	403	415	PF08784	0.282
LIG_SH2_CRK	409	413	PF00017	0.352
LIG_SH2_CRK	474	478	PF00017	0.390
LIG_SH2_GRB2like	743	746	PF00017	0.549
LIG_SH2_NCK_1	42	46	PF00017	0.483
LIG_SH2_NCK_1	57	61	PF00017	0.467
LIG_SH2_NCK_1	653	657	PF00017	0.608
LIG_SH2_PTP2	520	523	PF00017	0.447
LIG_SH2_PTP2	635	638	PF00017	0.384
LIG_SH2_SRC	226	229	PF00017	0.377
LIG_SH2_SRC	42	45	PF00017	0.509
LIG_SH2_SRC	57	60	PF00017	0.567
LIG_SH2_SRC	635	638	PF00017	0.445
LIG_SH2_SRC	664	667	PF00017	0.544
LIG_SH2_STAP1	924	928	PF00017	0.661
LIG_SH2_STAT3	443	446	PF00017	0.328
LIG_SH2_STAT3	581	584	PF00017	0.318
LIG_SH2_STAT3	743	746	PF00017	0.567
LIG_SH2_STAT5	226	229	PF00017	0.377
LIG_SH2_STAT5	395	398	PF00017	0.424
LIG_SH2_STAT5	443	446	PF00017	0.409
LIG_SH2_STAT5	476	479	PF00017	0.464
LIG_SH2_STAT5	520	523	PF00017	0.443
LIG_SH2_STAT5	581	584	PF00017	0.450
LIG_SH2_STAT5	635	638	PF00017	0.445
LIG_SH2_STAT5	646	649	PF00017	0.397
LIG_SH2_STAT5	650	653	PF00017	0.403
LIG_SH2_STAT5	743	746	PF00017	0.567
LIG_SH3_1	939	945	PF00018	0.533
LIG_SH3_3	143	149	PF00018	0.291
LIG_SH3_3	367	373	PF00018	0.535
LIG_SH3_3	474	480	PF00018	0.480
LIG_SH3_3	510	516	PF00018	0.409
LIG_SH3_3	567	573	PF00018	0.463
LIG_SH3_3	590	596	PF00018	0.510
LIG_SH3_3	614	620	PF00018	0.461
LIG_SH3_3	633	639	PF00018	0.521
LIG_SH3_3	925	931	PF00018	0.503
LIG_SH3_3	939	945	PF00018	0.533
LIG_SUMO_SIM_anti_2	313	320	PF11976	0.324
LIG_SUMO_SIM_anti_2	322	328	PF11976	0.322
LIG_SUMO_SIM_anti_2	518	527	PF11976	0.338
LIG_SUMO_SIM_par_1	188	193	PF11976	0.329
LIG_SUMO_SIM_par_1	198	203	PF11976	0.333
LIG_TRAF2_1	28	31	PF00917	0.678
LIG_TRAF2_1	663	666	PF00917	0.603
LIG_TYR_ITIM	354	359	PF00017	0.344
LIG_TYR_ITIM	633	638	PF00017	0.443
LIG_UBA3_1	3	8	PF00899	0.429
LIG_WW_3	594	598	PF00397	0.568
MOD_CDK_SPxxK_3	258	265	PF00069	0.539
MOD_CDK_SPxxK_3	781	788	PF00069	0.600
MOD_CK1_1	251	257	PF00069	0.614
MOD_CK1_1	295	301	PF00069	0.575
MOD_CK1_1	339	345	PF00069	0.416
MOD_CK1_1	441	447	PF00069	0.528
MOD_CK1_1	462	468	PF00069	0.339
MOD_CK1_1	540	546	PF00069	0.519
MOD_CK1_1	554	560	PF00069	0.475
MOD_CK1_1	677	683	PF00069	0.615
MOD_CK1_1	700	706	PF00069	0.718
MOD_CK1_1	717	723	PF00069	0.688
MOD_CK1_1	726	732	PF00069	0.741
MOD_CK1_1	83	89	PF00069	0.672
MOD_CK1_1	881	887	PF00069	0.545
MOD_CK2_1	21	27	PF00069	0.531
MOD_CK2_1	444	450	PF00069	0.487
MOD_CK2_1	512	518	PF00069	0.392
MOD_CK2_1	573	579	PF00069	0.394
MOD_CK2_1	598	604	PF00069	0.470
MOD_CK2_1	625	631	PF00069	0.529
MOD_CK2_1	660	666	PF00069	0.646
MOD_CK2_1	83	89	PF00069	0.703
MOD_CK2_1	849	855	PF00069	0.518
MOD_CK2_1	916	922	PF00069	0.572
MOD_CK2_1	978	984	PF00069	0.610
MOD_GlcNHglycan	250	253	PF01048	0.528
MOD_GlcNHglycan	269	272	PF01048	0.752
MOD_GlcNHglycan	294	297	PF01048	0.726
MOD_GlcNHglycan	426	429	PF01048	0.455
MOD_GlcNHglycan	457	460	PF01048	0.399
MOD_GlcNHglycan	52	55	PF01048	0.631
MOD_GlcNHglycan	570	573	PF01048	0.474
MOD_GlcNHglycan	676	679	PF01048	0.779
MOD_GlcNHglycan	702	705	PF01048	0.684
MOD_GlcNHglycan	71	74	PF01048	0.780
MOD_GlcNHglycan	716	719	PF01048	0.783
MOD_GlcNHglycan	759	762	PF01048	0.591
MOD_GlcNHglycan	772	775	PF01048	0.520
MOD_GlcNHglycan	801	804	PF01048	0.558
MOD_GlcNHglycan	85	88	PF01048	0.644
MOD_GlcNHglycan	871	874	PF01048	0.716
MOD_GlcNHglycan	875	878	PF01048	0.676
MOD_GlcNHglycan	89	92	PF01048	0.608
MOD_GlcNHglycan	975	978	PF01048	0.645
MOD_GSK3_1	120	127	PF00069	0.286
MOD_GSK3_1	174	181	PF00069	0.323
MOD_GSK3_1	186	193	PF00069	0.272
MOD_GSK3_1	251	258	PF00069	0.737
MOD_GSK3_1	325	332	PF00069	0.228
MOD_GSK3_1	342	349	PF00069	0.293
MOD_GSK3_1	362	369	PF00069	0.519
MOD_GSK3_1	371	378	PF00069	0.556
MOD_GSK3_1	416	423	PF00069	0.420
MOD_GSK3_1	441	448	PF00069	0.464
MOD_GSK3_1	451	458	PF00069	0.343
MOD_GSK3_1	508	515	PF00069	0.418
MOD_GSK3_1	526	533	PF00069	0.498
MOD_GSK3_1	543	550	PF00069	0.488
MOD_GSK3_1	693	700	PF00069	0.701
MOD_GSK3_1	705	712	PF00069	0.668
MOD_GSK3_1	714	721	PF00069	0.719
MOD_GSK3_1	765	772	PF00069	0.407
MOD_GSK3_1	79	86	PF00069	0.654
MOD_GSK3_1	819	826	PF00069	0.490
MOD_GSK3_1	869	876	PF00069	0.725
MOD_GSK3_1	9	16	PF00069	0.401
MOD_GSK3_1	943	950	PF00069	0.622
MOD_GSK3_1	978	985	PF00069	0.709
MOD_LATS_1	896	902	PF00433	0.513
MOD_N-GLC_1	124	129	PF02516	0.331
MOD_N-GLC_1	292	297	PF02516	0.750
MOD_N-GLC_1	336	341	PF02516	0.425
MOD_N-GLC_1	424	429	PF02516	0.271
MOD_N-GLC_1	554	559	PF02516	0.455
MOD_N-GLC_1	642	647	PF02516	0.336
MOD_N-GLC_1	769	774	PF02516	0.482
MOD_N-GLC_1	916	921	PF02516	0.680
MOD_N-GLC_2	499	501	PF02516	0.335
MOD_NEK2_1	178	183	PF00069	0.291
MOD_NEK2_1	190	195	PF00069	0.291
MOD_NEK2_1	227	232	PF00069	0.291
MOD_NEK2_1	325	330	PF00069	0.308
MOD_NEK2_1	346	351	PF00069	0.491
MOD_NEK2_1	359	364	PF00069	0.543
MOD_NEK2_1	455	460	PF00069	0.319
MOD_NEK2_1	765	770	PF00069	0.472
MOD_NEK2_1	79	84	PF00069	0.795
MOD_NEK2_1	848	853	PF00069	0.519
MOD_NEK2_1	9	14	PF00069	0.412
MOD_NEK2_1	982	987	PF00069	0.516
MOD_NEK2_2	459	464	PF00069	0.317
MOD_OFUCOSY	112	117	PF10250	0.380
MOD_OFUCOSY	495	501	PF10250	0.312
MOD_OFUCOSY	93	99	PF10250	0.459
MOD_PIKK_1	165	171	PF00454	0.291
MOD_PIKK_1	371	377	PF00454	0.435
MOD_PIKK_1	508	514	PF00454	0.495
MOD_PK_1	408	414	PF00069	0.365
MOD_PKA_1	174	180	PF00069	0.325
MOD_PKA_1	598	604	PF00069	0.470
MOD_PKA_1	674	680	PF00069	0.542
MOD_PKA_1	878	884	PF00069	0.567
MOD_PKA_2	149	155	PF00069	0.385
MOD_PKA_2	349	355	PF00069	0.445
MOD_PKA_2	598	604	PF00069	0.470
MOD_PKA_2	674	680	PF00069	0.629
MOD_PKA_2	685	691	PF00069	0.776
MOD_PKA_2	697	703	PF00069	0.629
MOD_PKA_2	765	771	PF00069	0.513
MOD_PKB_1	172	180	PF00069	0.325
MOD_PKB_1	672	680	PF00069	0.543
MOD_PKB_1	691	699	PF00069	0.520
MOD_PKB_1	75	83	PF00069	0.643
MOD_PKB_1	941	949	PF00069	0.670
MOD_Plk_1	312	318	PF00069	0.341
MOD_Plk_1	336	342	PF00069	0.454
MOD_Plk_1	424	430	PF00069	0.274
MOD_Plk_1	526	532	PF00069	0.403
MOD_Plk_1	642	648	PF00069	0.328
MOD_Plk_2-3	949	955	PF00069	0.520
MOD_Plk_4	174	180	PF00069	0.325
MOD_Plk_4	193	199	PF00069	0.291
MOD_Plk_4	228	234	PF00069	0.325
MOD_Plk_4	312	318	PF00069	0.362
MOD_Plk_4	417	423	PF00069	0.466
MOD_Plk_4	451	457	PF00069	0.363
MOD_Plk_4	462	468	PF00069	0.353
MOD_Plk_4	516	522	PF00069	0.325
MOD_Plk_4	543	549	PF00069	0.569
MOD_Plk_4	642	648	PF00069	0.401
MOD_Plk_4	697	703	PF00069	0.676
MOD_ProDKin_1	258	264	PF00069	0.687
MOD_ProDKin_1	339	345	PF00069	0.402
MOD_ProDKin_1	366	372	PF00069	0.517
MOD_ProDKin_1	420	426	PF00069	0.425
MOD_ProDKin_1	512	518	PF00069	0.355
MOD_ProDKin_1	584	590	PF00069	0.435
MOD_ProDKin_1	709	715	PF00069	0.652
MOD_ProDKin_1	781	787	PF00069	0.600
MOD_ProDKin_1	838	844	PF00069	0.581
MOD_ProDKin_1	97	103	PF00069	0.451
MOD_SUMO_for_1	828	831	PF00179	0.437
MOD_SUMO_rev_2	122	127	PF00179	0.347
MOD_SUMO_rev_2	235	241	PF00179	0.291
MOD_SUMO_rev_2	259	268	PF00179	0.541
MOD_SUMO_rev_2	751	761	PF00179	0.522
MOD_SUMO_rev_2	812	817	PF00179	0.668
MOD_SUMO_rev_2	821	830	PF00179	0.573
TRG_DiLeu_BaEn_2	830	836	PF01217	0.555
TRG_DiLeu_BaLyEn_6	14	19	PF01217	0.468
TRG_ENDOCYTIC_2	356	359	PF00928	0.356
TRG_ENDOCYTIC_2	409	412	PF00928	0.356
TRG_ENDOCYTIC_2	41	44	PF00928	0.627
TRG_ENDOCYTIC_2	474	477	PF00928	0.392
TRG_ENDOCYTIC_2	520	523	PF00928	0.477
TRG_ENDOCYTIC_2	635	638	PF00928	0.436
TRG_ENDOCYTIC_2	646	649	PF00928	0.427
TRG_ER_diArg_1	138	141	PF00400	0.325
TRG_ER_diArg_1	170	173	PF00400	0.291
TRG_ER_diArg_1	308	311	PF00400	0.533
TRG_ER_diArg_1	34	36	PF00400	0.588
TRG_ER_diArg_1	406	408	PF00400	0.454
TRG_ER_diArg_1	596	599	PF00400	0.592
TRG_ER_diArg_1	672	675	PF00400	0.595
TRG_ER_diArg_1	690	693	PF00400	0.557
TRG_ER_diArg_1	75	77	PF00400	0.675
TRG_ER_diArg_1	753	756	PF00400	0.674
TRG_ER_diArg_1	765	767	PF00400	0.554
TRG_ER_diArg_1	788	790	PF00400	0.560
TRG_ER_diArg_1	792	794	PF00400	0.552
TRG_ER_diArg_1	937	940	PF00400	0.632
TRG_ER_diArg_1	963	966	PF00400	0.603
TRG_ER_diArg_1	988	991	PF00400	0.673
TRG_NES_CRM1_1	130	145	PF08389	0.385
TRG_NES_CRM1_1	512	527	PF08389	0.455
TRG_NLS_MonoCore_2	961	966	PF00514	0.571
TRG_NLS_MonoCore_2	985	990	PF00514	0.673
TRG_NLS_MonoExtC_3	32	37	PF00514	0.576
TRG_NLS_MonoExtC_3	961	966	PF00514	0.573
TRG_NLS_MonoExtC_3	985	990	PF00514	0.673
TRG_NLS_MonoExtN_4	986	992	PF00514	0.670
TRG_Pf-PMV_PEXEL_1	140	145	PF00026	0.341

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IM29	Leptomonas seymouri	63%	100%
A0A1X0NZ48	Trypanosomatidae	44%	100%
A0A3S7WTU7	Leishmania donovani	77%	99%
A4HWT8	Leishmania infantum	77%	99%
C9ZPR7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	100%
E9AQJ6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	100%
Q4QEY1	Leishmania major	78%	99%