LIM domain-binding protein 3

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H8E2_LEIBR

TriTrypDb:

LbrM.16.0160 , LBRM2903_160006800

Length:

348

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H8E2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H8E2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	25	29	PF00656	0.489
CLV_NRD_NRD_1	225	227	PF00675	0.628
CLV_NRD_NRD_1	261	263	PF00675	0.593
CLV_NRD_NRD_1	332	334	PF00675	0.370
CLV_PCSK_KEX2_1	132	134	PF00082	0.501
CLV_PCSK_KEX2_1	224	226	PF00082	0.629
CLV_PCSK_KEX2_1	260	262	PF00082	0.718
CLV_PCSK_KEX2_1	332	334	PF00082	0.582
CLV_PCSK_PC1ET2_1	132	134	PF00082	0.501
CLV_PCSK_PC7_1	257	263	PF00082	0.594
CLV_PCSK_SKI1_1	3	7	PF00082	0.427
CLV_PCSK_SKI1_1	51	55	PF00082	0.446
CLV_PCSK_SKI1_1	68	72	PF00082	0.377
DEG_Nend_UBRbox_4	1	3	PF02207	0.456
DEG_ODPH_VHL_1	118	131	PF01847	0.484
DEG_SCF_FBW7_1	207	214	PF00400	0.647
DOC_CKS1_1	20	25	PF01111	0.481
DOC_CYCLIN_RxL_1	62	72	PF00134	0.397
DOC_CYCLIN_yCln2_LP_2	73	79	PF00134	0.443
DOC_MAPK_DCC_7	101	110	PF00069	0.478
DOC_MAPK_gen_1	109	118	PF00069	0.476
DOC_MAPK_MEF2A_6	101	110	PF00069	0.478
DOC_MAPK_MEF2A_6	30	37	PF00069	0.479
DOC_MAPK_MEF2A_6	68	77	PF00069	0.424
DOC_PP2B_LxvP_1	73	76	PF13499	0.438
DOC_PP4_FxxP_1	161	164	PF00568	0.461
DOC_PP4_FxxP_1	71	74	PF00568	0.429
DOC_USP7_MATH_1	181	185	PF00917	0.487
DOC_USP7_MATH_1	193	197	PF00917	0.492
DOC_USP7_MATH_1	213	217	PF00917	0.582
DOC_USP7_MATH_1	283	287	PF00917	0.619
DOC_USP7_MATH_1	292	296	PF00917	0.727
DOC_USP7_MATH_1	342	346	PF00917	0.538
DOC_USP7_MATH_1	46	50	PF00917	0.468
DOC_WW_Pin1_4	111	116	PF00397	0.473
DOC_WW_Pin1_4	19	24	PF00397	0.456
DOC_WW_Pin1_4	205	210	PF00397	0.600
DOC_WW_Pin1_4	211	216	PF00397	0.535
DOC_WW_Pin1_4	251	256	PF00397	0.553
DOC_WW_Pin1_4	6	11	PF00397	0.439
LIG_14-3-3_CanoR_1	171	179	PF00244	0.465
LIG_14-3-3_CanoR_1	30	36	PF00244	0.482
LIG_14-3-3_CanoR_1	51	60	PF00244	0.437
LIG_14-3-3_CanoR_1	62	71	PF00244	0.376
LIG_CtBP_PxDLS_1	115	119	PF00389	0.468
LIG_FHA_1	105	111	PF00498	0.475
LIG_FHA_1	132	138	PF00498	0.500
LIG_FHA_1	32	38	PF00498	0.470
LIG_FHA_1	335	341	PF00498	0.526
LIG_FHA_2	23	29	PF00498	0.486
LIG_LIR_Apic_2	158	164	PF02991	0.455
LIG_LIR_Nem_3	150	156	PF02991	0.549
LIG_Pex14_2	322	326	PF04695	0.565
LIG_RPA_C_Fungi	25	37	PF08784	0.483
LIG_SH2_CRK	173	177	PF00017	0.606
LIG_SH2_STAP1	173	177	PF00017	0.606
LIG_SH3_3	11	17	PF00018	0.451
LIG_SH3_3	117	123	PF00018	0.462
LIG_SH3_3	160	166	PF00018	0.588
LIG_SH3_3	212	218	PF00018	0.635
LIG_SH3_3	271	277	PF00018	0.535
LIG_SH3_3	32	38	PF00018	0.470
LIG_SH3_3	75	81	PF00018	0.448
LIG_SH3_CIN85_PxpxPR_1	164	169	PF14604	0.504
LIG_TRAF2_1	218	221	PF00917	0.630
LIG_WRC_WIRS_1	194	199	PF05994	0.489
MOD_CDC14_SPxK_1	214	217	PF00782	0.639
MOD_CDK_SPxK_1	211	217	PF00069	0.641
MOD_CDK_SPxK_1	251	257	PF00069	0.550
MOD_CK1_1	114	120	PF00069	0.466
MOD_CK2_1	86	92	PF00069	0.478
MOD_GlcNHglycan	173	176	PF01048	0.540
MOD_GlcNHglycan	283	286	PF01048	0.570
MOD_GlcNHglycan	294	297	PF01048	0.612
MOD_GSK3_1	203	210	PF00069	0.623
MOD_GSK3_1	86	93	PF00069	0.499
MOD_N-GLC_1	171	176	PF02516	0.462
MOD_NEK2_1	86	91	PF00069	0.518
MOD_OFUCOSY	87	94	PF10250	0.478
MOD_PIKK_1	46	52	PF00454	0.464
MOD_PKA_2	46	52	PF00069	0.464
MOD_PKB_1	169	177	PF00069	0.521
MOD_Plk_1	171	177	PF00069	0.592
MOD_ProDKin_1	111	117	PF00069	0.472
MOD_ProDKin_1	19	25	PF00069	0.458
MOD_ProDKin_1	205	211	PF00069	0.599
MOD_ProDKin_1	251	257	PF00069	0.556
MOD_ProDKin_1	6	12	PF00069	0.441
MOD_SUMO_rev_2	150	156	PF00179	0.410
TRG_DiLeu_BaLyEn_6	120	125	PF01217	0.513
TRG_ENDOCYTIC_2	173	176	PF00928	0.604
TRG_ER_diArg_1	108	111	PF00400	0.482
TRG_ER_diArg_1	168	171	PF00400	0.525
TRG_ER_diArg_1	223	226	PF00400	0.623
TRG_ER_diArg_1	259	262	PF00400	0.551
TRG_ER_diArg_1	331	333	PF00400	0.368

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WTR0	Leishmania donovani	61%	100%
A4HWR4	Leishmania infantum	61%	100%
Q4QF05	Leishmania major	61%	92%