BAH domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H8C6_LEIBR

TriTrypDb:

LbrM.15.1580 , LBRM2903_150022900

Length:

543

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H8C6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H8C6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	26	30	PF00656	0.377
CLV_C14_Caspase3-7	400	404	PF00656	0.620
CLV_NRD_NRD_1	217	219	PF00675	0.370
CLV_NRD_NRD_1	271	273	PF00675	0.544
CLV_NRD_NRD_1	374	376	PF00675	0.610
CLV_NRD_NRD_1	4	6	PF00675	0.571
CLV_NRD_NRD_1	84	86	PF00675	0.453
CLV_NRD_NRD_1	9	11	PF00675	0.511
CLV_PCSK_FUR_1	374	378	PF00082	0.584
CLV_PCSK_KEX2_1	217	219	PF00082	0.353
CLV_PCSK_KEX2_1	373	375	PF00082	0.604
CLV_PCSK_KEX2_1	376	378	PF00082	0.586
CLV_PCSK_KEX2_1	4	6	PF00082	0.563
CLV_PCSK_KEX2_1	418	420	PF00082	0.515
CLV_PCSK_KEX2_1	9	11	PF00082	0.518
CLV_PCSK_PC1ET2_1	376	378	PF00082	0.590
CLV_PCSK_PC1ET2_1	4	6	PF00082	0.592
CLV_PCSK_PC1ET2_1	418	420	PF00082	0.563
CLV_PCSK_PC7_1	414	420	PF00082	0.523
CLV_PCSK_PC7_1	5	11	PF00082	0.652
CLV_PCSK_SKI1_1	164	168	PF00082	0.424
CLV_PCSK_SKI1_1	243	247	PF00082	0.388
CLV_PCSK_SKI1_1	274	278	PF00082	0.514
CLV_PCSK_SKI1_1	414	418	PF00082	0.511
CLV_PCSK_SKI1_1	419	423	PF00082	0.482
CLV_PCSK_SKI1_1	437	441	PF00082	0.473
CLV_PCSK_SKI1_1	510	514	PF00082	0.690
DEG_ODPH_VHL_1	528	539	PF01847	0.501
DEG_SPOP_SBC_1	393	397	PF00917	0.503
DOC_CYCLIN_RxL_1	414	426	PF00134	0.573
DOC_CYCLIN_RxL_1	507	517	PF00134	0.626
DOC_CYCLIN_yCln2_LP_2	134	140	PF00134	0.400
DOC_MAPK_gen_1	272	279	PF00069	0.453
DOC_PP1_RVXF_1	119	126	PF00149	0.378
DOC_PP4_FxxP_1	141	144	PF00568	0.279
DOC_PP4_FxxP_1	70	73	PF00568	0.360
DOC_PP4_FxxP_1	76	79	PF00568	0.413
DOC_PP4_MxPP_1	71	74	PF00568	0.338
DOC_USP7_MATH_1	363	367	PF00917	0.701
DOC_USP7_MATH_1	391	395	PF00917	0.567
DOC_USP7_MATH_1	399	403	PF00917	0.710
DOC_USP7_UBL2_3	365	369	PF12436	0.542
DOC_USP7_UBL2_3	484	488	PF12436	0.643
DOC_WW_Pin1_4	367	372	PF00397	0.712
DOC_WW_Pin1_4	387	392	PF00397	0.452
DOC_WW_Pin1_4	43	48	PF00397	0.386
DOC_WW_Pin1_4	482	487	PF00397	0.706
DOC_WW_Pin1_4	491	496	PF00397	0.537
LIG_14-3-3_CanoR_1	101	105	PF00244	0.663
LIG_14-3-3_CanoR_1	431	439	PF00244	0.558
LIG_14-3-3_CanoR_1	533	539	PF00244	0.505
LIG_Actin_WH2_2	228	245	PF00022	0.507
LIG_eIF4E_1	55	61	PF01652	0.325
LIG_FHA_1	151	157	PF00498	0.421
LIG_FHA_1	48	54	PF00498	0.383
LIG_FHA_1	55	61	PF00498	0.274
LIG_FHA_2	222	228	PF00498	0.530
LIG_FHA_2	338	344	PF00498	0.750
LIG_FHA_2	465	471	PF00498	0.654
LIG_LIR_Apic_2	139	144	PF02991	0.328
LIG_LIR_Apic_2	342	348	PF02991	0.695
LIG_LIR_Gen_1	204	215	PF02991	0.464
LIG_LIR_Gen_1	288	297	PF02991	0.479
LIG_LIR_Gen_1	426	434	PF02991	0.584
LIG_LIR_Gen_1	471	482	PF02991	0.622
LIG_LIR_Nem_3	130	135	PF02991	0.364
LIG_LIR_Nem_3	204	210	PF02991	0.498
LIG_LIR_Nem_3	248	253	PF02991	0.433
LIG_LIR_Nem_3	288	292	PF02991	0.396
LIG_LIR_Nem_3	426	432	PF02991	0.510
LIG_LIR_Nem_3	471	477	PF02991	0.543
LIG_MYND_1	495	499	PF01753	0.479
LIG_MYND_1	520	524	PF01753	0.493
LIG_PTB_Apo_2	64	71	PF02174	0.390
LIG_REV1ctd_RIR_1	437	446	PF16727	0.559
LIG_SH2_CRK	289	293	PF00017	0.345
LIG_SH2_CRK	294	298	PF00017	0.342
LIG_SH2_GRB2like	249	252	PF00017	0.492
LIG_SH2_PTP2	345	348	PF00017	0.680
LIG_SH2_SRC	345	348	PF00017	0.599
LIG_SH2_SRC	454	457	PF00017	0.537
LIG_SH2_STAP1	147	151	PF00017	0.453
LIG_SH2_STAP1	261	265	PF00017	0.314
LIG_SH2_STAP1	406	410	PF00017	0.525
LIG_SH2_STAT3	124	127	PF00017	0.357
LIG_SH2_STAT5	124	127	PF00017	0.363
LIG_SH2_STAT5	133	136	PF00017	0.375
LIG_SH2_STAT5	150	153	PF00017	0.339
LIG_SH2_STAT5	345	348	PF00017	0.687
LIG_SH2_STAT5	349	352	PF00017	0.707
LIG_SH2_STAT5	428	431	PF00017	0.574
LIG_SH3_1	345	351	PF00018	0.654
LIG_SH3_2	35	40	PF14604	0.411
LIG_SH3_3	172	178	PF00018	0.382
LIG_SH3_3	32	38	PF00018	0.393
LIG_SH3_3	345	351	PF00018	0.686
LIG_SH3_3	41	47	PF00018	0.387
LIG_SH3_3	492	498	PF00018	0.484
LIG_SUMO_SIM_anti_2	114	120	PF11976	0.483
LIG_SUMO_SIM_anti_2	177	183	PF11976	0.427
LIG_TRAF2_2	450	455	PF00917	0.714
LIG_TRFH_1	133	137	PF08558	0.392
LIG_TYR_ITIM	292	297	PF00017	0.345
MOD_CDC14_SPxK_1	485	488	PF00782	0.469
MOD_CDK_SPxK_1	367	373	PF00069	0.520
MOD_CDK_SPxK_1	482	488	PF00069	0.469
MOD_CDK_SPxxK_3	367	374	PF00069	0.520
MOD_CK1_1	100	106	PF00069	0.666
MOD_CK1_1	382	388	PF00069	0.592
MOD_CK1_1	389	395	PF00069	0.582
MOD_CK1_1	401	407	PF00069	0.528
MOD_CK1_1	430	436	PF00069	0.554
MOD_CK1_1	443	449	PF00069	0.610
MOD_CK1_1	506	512	PF00069	0.613
MOD_CK1_1	531	537	PF00069	0.743
MOD_CK2_1	221	227	PF00069	0.403
MOD_CK2_1	337	343	PF00069	0.659
MOD_CK2_1	354	360	PF00069	0.599
MOD_CK2_1	469	475	PF00069	0.534
MOD_Cter_Amidation	92	95	PF01082	0.402
MOD_GlcNHglycan	111	116	PF01048	0.576
MOD_GlcNHglycan	204	207	PF01048	0.457
MOD_GlcNHglycan	235	238	PF01048	0.464
MOD_GlcNHglycan	269	272	PF01048	0.430
MOD_GlcNHglycan	313	316	PF01048	0.523
MOD_GlcNHglycan	391	394	PF01048	0.578
MOD_GlcNHglycan	432	435	PF01048	0.564
MOD_GSK3_1	100	107	PF00069	0.520
MOD_GSK3_1	221	228	PF00069	0.409
MOD_GSK3_1	363	370	PF00069	0.554
MOD_GSK3_1	382	389	PF00069	0.567
MOD_GSK3_1	391	398	PF00069	0.596
MOD_GSK3_1	43	50	PF00069	0.413
MOD_GSK3_1	459	466	PF00069	0.594
MOD_GSK3_1	528	535	PF00069	0.675
MOD_N-GLC_1	285	290	PF02516	0.512
MOD_N-GLC_1	317	322	PF02516	0.522
MOD_N-GLC_1	460	465	PF02516	0.508
MOD_N-GLC_1	55	60	PF02516	0.366
MOD_NEK2_1	267	272	PF00069	0.494
MOD_NEK2_1	285	290	PF00069	0.411
MOD_NEK2_1	440	445	PF00069	0.687
MOD_NEK2_1	54	59	PF00069	0.354
MOD_PIKK_1	225	231	PF00454	0.521
MOD_PIKK_1	440	446	PF00454	0.620
MOD_PIKK_1	448	454	PF00454	0.726
MOD_PK_1	379	385	PF00069	0.497
MOD_PKA_2	100	106	PF00069	0.609
MOD_PKA_2	430	436	PF00069	0.608
MOD_PKA_2	532	538	PF00069	0.577
MOD_PKB_1	377	385	PF00069	0.595
MOD_Plk_1	285	291	PF00069	0.459
MOD_Plk_1	317	323	PF00069	0.525
MOD_Plk_1	379	385	PF00069	0.588
MOD_Plk_1	460	466	PF00069	0.501
MOD_Plk_1	47	53	PF00069	0.502
MOD_Plk_1	55	61	PF00069	0.243
MOD_Plk_2-3	337	343	PF00069	0.666
MOD_Plk_2-3	354	360	PF00069	0.570
MOD_Plk_2-3	469	475	PF00069	0.475
MOD_Plk_4	100	106	PF00069	0.612
MOD_Plk_4	245	251	PF00069	0.501
MOD_Plk_4	382	388	PF00069	0.495
MOD_Plk_4	49	55	PF00069	0.410
MOD_Plk_4	56	62	PF00069	0.323
MOD_ProDKin_1	367	373	PF00069	0.712
MOD_ProDKin_1	387	393	PF00069	0.451
MOD_ProDKin_1	43	49	PF00069	0.393
MOD_ProDKin_1	482	488	PF00069	0.707
MOD_ProDKin_1	491	497	PF00069	0.538
MOD_SUMO_for_1	489	492	PF00179	0.707
MOD_SUMO_rev_2	258	267	PF00179	0.315
MOD_SUMO_rev_2	361	371	PF00179	0.515
MOD_SUMO_rev_2	89	96	PF00179	0.528
TRG_DiLeu_BaEn_4	262	268	PF01217	0.447
TRG_ENDOCYTIC_2	282	285	PF00928	0.381
TRG_ENDOCYTIC_2	289	292	PF00928	0.343
TRG_ENDOCYTIC_2	294	297	PF00928	0.349
TRG_ER_diArg_1	216	218	PF00400	0.337
TRG_ER_diArg_1	240	243	PF00400	0.464
TRG_ER_diArg_1	291	294	PF00400	0.342
TRG_ER_diArg_1	373	375	PF00400	0.597
TRG_ER_diArg_1	8	10	PF00400	0.555
TRG_NLS_MonoExtC_3	3	8	PF00514	0.572
TRG_NLS_MonoExtC_3	374	379	PF00514	0.599
TRG_NLS_MonoExtN_4	2	8	PF00514	0.585
TRG_NLS_MonoExtN_4	373	379	PF00514	0.530
TRG_Pf-PMV_PEXEL_1	419	424	PF00026	0.554

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P791	Leptomonas seymouri	66%	100%
A0A1X0NGQ9	Trypanosomatidae	42%	92%
A0A3R7L2Y6	Trypanosoma rangeli	42%	91%
A0A3S5H6W3	Leishmania donovani	79%	100%
A4HWP7	Leishmania infantum	79%	100%
C9ZTQ6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	87%
E9AQF5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%
Q4QF21	Leishmania major	77%	100%
V5DPP9	Trypanosoma cruzi	43%	92%